Contemporary Results of Transcatheter Aortic Valve Replacement in Obese Patients by T. Owais, M. El Garhy, P. Lauten, M. Haensig, H. Lapp, P. C. Schulze, T. Kuntze

“…We found no differences in valve types and sizes among the different BMI categories. Our mortality rate during the 1-year follow-up period was 17.8% (287 patients). …”
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Characterization and comparison of gut microbiota in patients with acute pancreatitis by metagenomics and culturomics by Liang Gong, Xue Li, Li Ji, Guorong Chen, Ziying Han, Lei Su, Dong Wu

“…Acute pancreatitis (AP) is a common gastrointestinal disorder with a high mortality rate. This study sought to identify the microbial community structure in patients with AP using metagenomics and culturomics. …”
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Multiphoton imaging-based quantifiable collagen signatures for predicting outcomes in patients with pancreatic ductal adenocarcinoma by Xiwen Chen, Jikui Miao, Xingxin Huang, Xiahui Han, Liqin Zheng, Jianxin Chen, Linying Chen, Lianhuang Li

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) presents a clinical challenge due to its poor prognosis and high mortality rate. Here, we aimed to enhance the prognostic prediction of patients with PDAC by studying collagen features in tumor microenvironment using multiphoton microscopy (MPM) combining with image processing technique. …”
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Mortality-related risk factors of carbapenem-resistant Enterobacteriaceae infection with focus on antimicrobial regimens optimization: a real-world retrospective study in China by Sheng Deng, Jinglan Chen, Pengxiang Zhou, Qin Hu

“…Since patients with non-sepsis have a lower mortality rate from monotherapy, combination antibiotic treatment should not be routinely recommended. …”
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IL-6 and PD-1 antibody blockade combination therapy regulate inflammation and T lymphocyte apoptosis in murine model of sepsis by Song I Lee, Na Young Kim, Chaeuk Chung, Dongil Park, Da Hyun Kang, Duk Ki Kim, Min-Kyung Yeo, Pureum Sun, Jeong Eun Lee

“…Peripheral blood count, cytokine level, lymphocyte apoptosis in the spleen, neutrophil infiltration in the lungs and liver, and survival rate were measured. The mortality rate of the IL-6/PD-1 group was lower, though not statistically significant (p = 0.164), than that of CLP mice (75.0% vs. 91.7%). …”
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Global, regional and national epidemiological trends of multiple myeloma from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021 by Linmin Zhuge, Xiaowu Lin, Ziwei Fan, Mengxian Jia, Chaowei Lin, Minyu Zhu, Honglin Teng, Guoliang Chen

“…MM primarily affects older adults, with the highest incidence observed in the 70–74 age group and the highest mortality rate recorded in the same age range.ConclusionMM presents an escalating global health challenge. …”
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TransRAUNet: A Deep Neural Network with Reverse Attention Module Using HU Windowing Augmentation for Robust Liver Vessel Segmentation in Full Resolution of CT Images by Kyoung Yoon Lim, Jae Eun Ko, Yoo Na Hwang, Sang Goo Lee, Sung Min Kim

“…<b>Background:</b> Liver cancer has a high mortality rate worldwide, and clinicians segment liver vessels in CT images before surgical procedures. …”
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Telomerase and mitochondria inhibition promote apoptosis and TET2 and ANMT3a expression in triple negative breast cancer cell lines by Zeinab Mazloumi, Ali Rafat, Khadijeh Dizaji Asl, Mohammad Karimipour, Dariush Shanehbandi, Mehdi Talebi, Majid Montazer, Ali Akbar Movassaghpour, Alireza Dehnad, Raheleh Farahzadi, Hojjatollah Nozad Charoudeh

“…Introduction: High metastasis, resistance to common treatments, and high mortality rate, has made triple-negative breast cancer (TNBC) to be the most invasive type of breast cancer. …”
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Clinical characteristics and outcomes of children with COVID-19 in pediatric intensive care units during the Omicron wave in Taiwan by Jeng-Hung Wu, Ching-Chia Wang, Frank Leigh Lu, Shu-Chien Huang, Ting-Yu Yen, Chun-Yi Lu, Luan-Yin Chang, En-Ting Wu

“…Results: We enrolled 78 children with COVID-19, with a median length of stay (LOS) in PICU of 3 days and a 5% mortality rate. Patients admitted during the early stage had lower vaccination rates (7% vs. 50%), higher pediatric logistic organ dysfunction scores (2 vs. 0.1), and longer LOS in the PICU (6 vs. 2 days) than those admitted during the late stage. …”
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Sociodemographic factors associated with dental students knowledge and attitudes regarding disinfection as a control measure to reduce the spread of COVID-19 by Geanella Silva-Robles, Gissela Briceño-Vergel, Rosa Aroste-Andía, Emily Hernández-Huamaní, Marysela Ladera-Castañeda, Miriam Castro-Rojas, Percy Gavilán-Chávez, Luis Cervantes-Ganoza, César Cayo-Rojas

“…Abstract Despite maintaining a lower mortality rate and greater control of victims infected by COVID-19, the world’s population and science are still confronted with this coronavirus. …”
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Poor Glycemic Control in Carbapenem-Resistant Klebsiella pneumoniae Infections: Impact on Epidemiological Features, Mortality Risks, and Polymyxin Resistance by Wang Q, Yan T, Ma C, Teng X, Shen C, Wang N, Yu K, Chu W, Zhou Q, Liu Z

“…They also exhibited an increased mortality rate. Logistic regression analysis identified age, glycosylated hemoglobin (HbA1c) ≥ 7%, CKD, tumor, mechanical ventilation, and sepsis as independent risk factors for death associated with CRKP infection. …”
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Changes in anaphylaxis trends and characteristics in emergency department admissions in Türkiye: From 2015 to 2021 based on the Ministry of Health database by Elif Soyak Aytekin, MD, Seda Şirin, MD, Esra Kıratlı Nalbant, MD, Naim Ata, MD, Ahmet Sertçelik, MD, Mustafa Mahir Ülgü, MD, Şuayip Birinci, MD, Koray Harmancı, MD, Zülfikar Akelma, MD

“…The frequency of intensive care unit (ICU) hospitalization increased 6.0-fold from 2015 to 2021, and age-adjusted average-weighted mortality rate for anaphylaxis was 0.66 per million. Older age, presence of asthma, and ICU hospitalization were found to be significantly associated with fatal anaphylaxis (p < 0.001 for all). …”
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Exploring the anti-metastatic potential of sunitinib and novel analogs in colorectal cancer: insights into HIF-1α mediated metastasis by Fatemeh B. Rassouli, Maryam M. Matin, Maryam M. Matin, Farzin Hadizadeh, Farzin Hadizadeh, Masoud Nejabat, Hossein Allahverdizadeh, Hamidreza Jamali, Shahin Gharedaghi, Halimeh Hassanzadeh

“…IntroductionColorectal cancer (CRC) is a prevalent malignancy worldwide with high mortality rate. Metastasis, the primary cause of cancer-related deaths, is attributed to various factors including tumor hypoxia. …”
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Characteristics and Outcomes of Elderly Patients Refused to ICU by María-Consuelo Pintado, Patricia Villa, Natalia González-García, Jimena Luján, Rocío Molina, María Trascasa, Esther López-Ramos, Cristina Martínez, José-Andrés Cambronero, Raúl de Pablo

“…Patients refused because they were “too ill to benefit” had more comorbidity and worse functional and mental situation than those admitted to ICU; there were no differences in illness severity. Hospital mortality rate of the whole study cohort was 36.3%, higher in patients “too ill to benefit” (55.6% versus 35.8%, P<0.01), which also have higher 1-year mortality (73.7% versus 42.5%, P<0.01). …”
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Noncoding RNAs in sepsis-associated acute liver injury: Roles, mechanisms, and therapeutic applications by Jialian Wang, Xingyu Tao, Zhengyang Liu, Yuan Yan, Peifeng Cheng, Bin Liu, Huimin Du, Bailin Niu

“…In intensive care units (ICUs), the mortality rate of patients with SA-ALI remains high, mostly due to the absence of effective early diagnostic markers and suitable therapeutic strategies. …”
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Toxic Assessment of Heavily Traffic-related Fine Particulate Matter Using an in-vivo Wild-type Caenorhabditis elegans Model by Meng-Ching Chung, Kuo-Lin Huang, Japheth L. Avelino, Lemmuel L. Tayo, Chih-Chung Lin, Ming-Hsien Tsai, Sheng-Lun Lin, Wan Nurdiyana Wan Mansor, Ching-Kai Su, Sen-Ting Huang

“…Abstract In association with the mortality rate due to air pollution, vehicular emitted fine particles (PM2.5) are a threat to public health. …”
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Pathogenicity and Whole Genome Sequence Analysis of a Pseudorabies Virus Strain FJ-2012 Isolated from Fujian, Southern China by Xue-min Wu, Qiu-yong Chen, Ru-jing Chen, Yong-liang Che, Long-bai Wang, Chen-yan Wang, Shan Yan, Yu-tao Liu, Jin-sheng Xiu, Lun-jiang Zhou

“…FJ-2012-infected piglets developed symptoms like high body temperature and central nervous system disorders and had high mortality rate. In addition, we identified typical micropathological changes such as multiple gross lesions in infected piglets through pathological analysis and conclude that the FJ-2012 genome is significantly different from known pseudorabies viruses, in which insertions, deletions, and substitutions are observed in multiple immune and virulence genes. …”
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Vitamin D supplementation during intensive care unit stay is associated with improved outcomes in critically Ill patients with sepsis: a cohort study by Caifeng Li, Ke Zhao, Qian Ren, Lin Chen, Ying Zhang, Guolin Wang, Keliang Xie

“…In PSM analysis, the 28-day all-cause mortality rate was 14.04% (250/1780) in the vitamin D group and 22.31% (1546/6930) in the no vitamin D group. …”
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Mortality and Morbidity of Beef Calves in Free-Range Farms in Alentejo, Portugal—A Preliminary Study by Rute Santos, Ana Cachapa, Graça P. Carvalho, Carolina B. Silva, Laura Hernández, Lina Costa, Luísa S. Pereira, Miguel Minas, Helena Vala

“…The percent of live births that resulted in weaned calves averaged 94.3%, which led to the assumption of a 5.7% calf mortality rate from birth to weaning. In the previous 12 months, 78.8% of the farms identified at least one case of calf diarrhea, 60.7% identified at least one case of respiratory disease, and 82.1% had at least one sudden, unexplained calf death. …”
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Profile of Egyptian pediatrics with COVID-19: insights from healthcare providers in Egypt by Salma ZEl Houchi, Hanaa I. Rady, Iman Iskander, Tamer Abdel Hamid, Salma Abdelrehim Seddik, Amira Aly Hegazy, Ahmed Taha Aboushady, Mohamed Eissa, Sherine Khamis Hussein, Dina Hanoura, Miriam Magdy Aziz, Remon Magdy, Heba Ahmed ElAwady, Esraa A. Elmazzahy

“…The severity of the disease varied, with infants under one year of age having the highest percentage of severe and critical cases, with a 15% the mortality rate, when compared to other age groups. Conclusion COVID-19 has a wide clinical spectrum of diseases ranging from asymptomatic to severe and critical. …”
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