-
901
DLAT is involved in ovarian cancer progression by modulating lipid metabolism through the JAK2/STAT5A/SREBP1 signaling pathway
Published 2025-01-01“…Abstract Background Ovarian cancer (OC) remains a lethal gynecological malignancy with an alarming mortality rate, primarily attributed to delayed diagnosis and a lack of effective treatment modalities. …”
Get full text
Article -
902
Parametric modeling of under-5 children survival among 30 African countries: Lognormal accelerated failure time gamma shared frailty model.
Published 2025-01-01“…<h4>Result</h4>The overall under-five child mortality rate in Africa was 37.55 per 1,000 live births (95% CI: 37.35, 37.74. …”
Get full text
Article -
903
Retrospective cohort study based on the MIMIC-IV database: analysis of factors influencing all-cause mortality at 30 days, 90 days, 1 year, and 3 years in patients with different t...
Published 2025-01-01“…Random forest and gradient boosting tree models were employed for data analysis to assess mortality risk.ResultsKaplan–Meier survival analysis showed that ischemic stroke patients had the highest 30-day mortality rate at 8.5%, with only 20% 1-year survival. …”
Get full text
Article -
904
Quantifying uncertainty in anthropogenic causes of injury and mortality for an endangered baleen whale
Published 2024-12-01“…The model results also suggested that despite vessel strikes causing a lower average rate of severe injuries, the higher mortality rate conditional on injury results in significant total mortality risk, particularly for females resting from a recent calving event. …”
Get full text
Article -
905
Cardiovascular toxicity of tisagenlecleucel in children and adolescents: analysis of spontaneous reports submitted to FAERS
Published 2025-01-01“…Patients who developed shock had the highest mortality rate (66.67%). Concomitant use of medication for a neurological disorder was an independent risk factor for CVAEs, and concomitant use of medication for a respiratory disease was an independent risk factor for fatal CVAEs. …”
Get full text
Article -
906
Use of isavuconazole in mucormycosis: a systematic review
Published 2025-01-01“…A total of 31 articles, which included four case series, 24 case reports, one open-label trial, one randomized controlled trial, and one non-interventional registry study, were included in the final analysis. 135 adult patients and 14 children were treated with isavuconazole as primary monotherapy, primary combination therapy, nonprimary monotherapy, or nonprimary combination therapy. The mortality rate following LAmB monotherapy, amphotericin B plus azole, amphotericin B followed with azole, posaconazole only and isavuconazole only was 32%, 6.6%, 13.7%, 17.2% and 24.6%, respectively. …”
Get full text
Article -
907
Evaluation of the Antitumor Effects of Platinum-Based [Pt(η1-C2H4-OR)(DMSO)(phen)]+ (R = Me, Et) Cationic Organometallic Complexes on Chemoresistant Pancreatic Cancer Cell Lines...
Published 2023-01-01“…Pancreatic cancer is one of the most lethal malignancies with an increasing incidence and a high mortality rate, due to its rapid progression, invasiveness, and resistance to anticancer therapies. …”
Get full text
Article -
908
Diagnostic performance of the DISQVER metagenomic sequencing tool for the identification of pathogens in febrile neutropenic patients: the ADNEMIA trial
Published 2025-01-01“…Considering that without an identified pathogen, a 10% mortality rate can ensue, documentation is essential to the optimisation of antibiotic therapy. …”
Get full text
Article -
909
Activities of daily living after surgery among older patients with gastrointestinal and hepatobiliary-pancreatic cancers: a retrospective observational study using nationwide healt...
Published 2023-05-01“…The postoperative mortality rate was <3% (<10 cases) across all ages and cancer types.Conclusions In ESD/EMR, postoperative ADL decline was almost the same between older and younger patients. …”
Get full text
Article -
910
Prognostic Value of Endothelial Progenitor Cells in Acute Myocardial Infarction Patients
Published 2023-01-01“…In the univariate analysis, it was observed that the 28-days mortality rate was associated with the several factors, including the APACHEⅡscore (P=0.00), vasoactive inotropic score (P=0.03), GAP (P=0.00), HCY (P=0.00), creatinine (P=0.00), C-reactive protein (P=0.00), HbAlc (P=0.00), CI (P=0.01), quartiles of CD34+/CD133+ cells (P=0.00), and quartiles of CD34+/CD133+/KDR+ cells (P=0.00). …”
Get full text
Article -
911
Clinical features and factors associated with short-term prognosis in patients with pulmonary embolism
Published 2021-07-01“…Conclusions. There is a high mortality rate within 30 days (13.3 %) in hospitalized patients with acute PE, including 26 % of high-risk patients and 10.3 % of intermediate-high risk. …”
Get full text
Article -
912
Reproductive Health Services and Quality of Health Status of Woman in Kyanamira Sub-County Kabale District.
Published 2024“…Community sensitization on how to review some of the counseling and testing procedures so as to encourage reproductive mothers to test on before giving birth and there is need for government intervention on reproductive health care services among adolescent mothers and quality of health status with in Kyanamira sub-county Kabale district and people should join in the fight against sexual transmitted diseases by not cooperate with ignorance or primitive mothers on individuals and officials basis, Basing on study objectives, the study included that there were the importance of reproductive health services and quality of health status of Women in Kyanamira sub-county Kabale district as they included: health care quality, increased mortality rate, hospital committee, early detection, behavioral change, age of an individual, famil y influence, stigma and cervical education with, were chal enges faced by reproductive health care services by women in Kyanamira sub-county Kabale district as they included; poverty, trust, culture, care, lack of government concern, ignorance, family size and lack of access to informa t ion and possible ways in which Reproductive health services and quality of health status of women can be strengthen its services in Kyanamira sub-county Kabale district as they included; palative care, clinical care, spiritual care, social care, psychological support, government concern and community sensitization.…”
Get full text
Thesis -
913
Application of a deep learning algorithm for the diagnosis of HCC
Published 2025-01-01“…Background & Aims: Hepatocellular carcinoma (HCC) is characterized by a high mortality rate. The Liver Imaging Reporting and Data System (LI-RADS) results in a considerable number of indeterminate observations, rendering an accurate diagnosis difficult. …”
Get full text
Article -
914
Effects of low-flux and high-flux hemodialysis on the survival of elderly maintenance hemodialysis patients
Published 2024-12-01“…High-flux hemodialysis did not improve all-cause mortality rate. Differences in urea distribution volume, blood flow, and systemic differences in solute clearance by dialyzers were not further analyzed, which are the limitations of this study.…”
Get full text
Article -
915
The Role of Pentacyclic Triterpenoids in Non-Small Cell Lung Cancer: The Mechanisms of Action and Therapeutic Potential
Published 2024-12-01“…Lung cancer remains a major global health problem because of its high cancer-related mortality rate despite advances in therapeutic approaches. …”
Get full text
Article -
916
Implications of the availability and distribution of birth weight on addressing neonatal mortality: population-based assessment from Bihar state of India
Published 2022-06-01“…We report on birth weight availability, LBW prevalence, neonatal mortality rate (NMR) by birth weight and perceptions of mothers on LBW implications.Setting Bihar state, India.Participants Women with live birth between October 2018 and September 2019.Results A total of 5021 (83.5%) live births participated, and 3939 (78.4%) were weighed at birth. …”
Get full text
Article -
917
Antiviral Activity of Plant‐Based Additives Against African Swine Fever Virus (ASFV) in Feed Ingredients
Published 2024-11-01“…ABSTRACT Background African swine fever (ASF) is one of the deadliest swine diseases with haemorrhagic symptoms and a high mortality rate. Plant‐derived additives are potential antiviral agents against viruses due to their environmental and user‐friendly properties. …”
Get full text
Article -
918
Major Aortopulmonary Collateral Arteries and Their Effects on Perioperative Parameters and Mortality of Children with Tetralogy of Fallot: A Case-control Study
Published 2024-12-01“…Besides, perioperative parameters and mortality rates of our TOF patients with and without MAPCA were compared. …”
Get full text
Article -
919
Comparative Analysis of <i>In Vivo</i> and <i>In Vitro</i> Virulence Among Foodborne and Clinical <i>Listeria monocytogenes</i> Strains
Published 2025-01-01“…There were significant differences among isolates in terms of their mortality rate in <i>Galleria mellonella</i>, cytotoxicity to JEG-3 cells, hemolytic activity, and expression of important virulence genes. …”
Get full text
Article -
920
Peroxiredoxin 6 Attenuates Alloxan-Induced Type 1 Diabetes Mellitus in Mice and Cytokine-Induced Cytotoxicity in RIN-m5F Beta Cells
Published 2020-01-01“…It was shown that PRDX6 prevented hyperglycemia, lowered the mortality rate, restored the plasma cytokine profile, reversed the splenic cell apoptosis, and reduced the β cell destruction in Langerhans islets in mice with a severe form of alloxan-induced diabetes. …”
Get full text
Article