Is a Single Low Dose of Intrathecal Morphine a Useful Adjunct to Patient-Controlled Analgesia for Postoperative Pain Control Following Lumbar Spine Surgery?... by David Yen, Kim Turner, David Mark

“…BACKGROUND: Several studies addressing intrathecal morphine (ITM) use following spine surgery have been published either involving the pediatric population, using mid- to high-dose ITM, or not in conjunction with morphine patient-controlled analgesia (PCA).…”
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Intranasal Pharmacokinetics of Morphine ARER, a Novel Abuse-Deterrent Formulation: Results from a Randomized, Double-Blind, Four-Way Crossover Study in Nondependent, Opioid-Experienced Subjects by Lynn R. Webster, Carmela Pantaleon, Matthew Iverson, Michael D. Smith, Eric R. Kinzler, Stefan Aigner

“…To investigate the pharmacokinetics (PK) of Morphine ARER, an extended-release (ER), abuse-deterrent formulation of morphine sulfate after oral and intranasal administration. …”
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Uluslararası Afyon Anlaşmalarında Osmanlı İmparatorluğu by Burak Çıtır

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Modification of Gene Expression Involved in Alkaloid Production in Opium Poppy by VIGS Combined With Pretreatment of Macerozyme Enzyme by Deniz Ece Özcan, Deniz Köm, Ozan Doğan, Semiha Erişen, Selma Onarici

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Continuous Intra-Incisional Bupivacaine for Postoperative Analgesia after Hip Nailing Surgery: A Randomized Clinical Trial by Arash Farbood, Sanaz Abbasi, Naeimehossadat Asmarian, Mahsa Banifatemi, Vida Naderi-boldaji, Zeinabsadat Fattahi Saravi

“…In the ward, all control group patients used the PCA morphine pump, while only 54% of the bupivacaine group self-administered morphine through the pump, with a significantly lower total morphine consumption (1 (0–2) vs. 10 (5–14) mg, P<0.001). …”
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Effects of Addition of Preoperative Intravenous Ibuprofen to Pregabalin on Postoperative Pain in Posterior Lumbar Interbody Fusion Surgery by Hüseyin Ulaş Pınar, Ömer Karaca, Fatma Karakoç, Rafi Doğan

“…Postoperative analgesia was obtained by morphine patient controlled analgesia (PCA) and 1 g i.v. paracetamol every six hours. …”
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Study on Main Drugs and Drug Combinations of Patient-Controlled Analgesia Based on Text Mining by Xing Jin, Ying Wu

“…The maximum frequent 1-itemset was {Morphine} and the maximum frequent 2-itemset was {Morphine, Ropivacaine}. …”
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Transversus Abdominis Plane Catheter Bolus Analgesia after Major Abdominal Surgery by Nils Bjerregaard, Lone Nikolajsen, Thomas Fichtner Bendtsen, Bodil Steen Rasmussen

“…Cumulative consumption of intravenous morphine was 28 (23–48) mg (median, IQR) within the first 48 postoperative hours. …”
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Lateral Quadratus Lumborum Block versus Transversus Abdominis Plane Block in Laparoscopic Surgery: A Randomized Controlled Study by Omar Sayed Fargaly, Maged Labib Boules, Mohamed Ahmed Hamed, Mohammed Abdel Aleem Abbas, Mohammed Ahmed Shawky

“…The first outcome was the growing morphine consumption on the 1st day postoperatively. …”
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Analgesic Efficacy of Combined Adductor Canal and Popliteal Plexus Blocks Versus Adductor Canal Block Alone in Arthroscopic Knee Surgery: A Prospective, Double-Blinded, Randomized... by Ghada Magdy Behery, Nadia Hassan Fattoh, Mohammad Ali Mohammad Abduallah, Shimaa Elsaied Ibrahim Shaban

“…Outcome parameters were 24-h morphine consumption, time-to-first rescue analgesia, and postoperative pain. …”
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Randomized controlled trial comparing quadratus Lumborum Block and Surgical Site Infiltration in Total Abdominal Hysterectomy: Efficacy Analysis by Sangeeta Dhanger, R L Jayavani, Bhavani Vaidiyanathan, Idhuyya Joseph Rajesh

“…The primary outcomes measured were the time to first request for analgesia and total morphine consumption within the first 24 h postoperatively. …”
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Single Dose Intravenous Paracetamol versus Placebo in Postorthognathic Surgery Pain: A Randomized Clinical Trial by Thunshuda Sumphaongern, Pornchai Jansisyanont

“…The visual analogue pain scale (VAS) at 1-, 4-, 8-, 12-, 16-, 20-, and 24 -h postoperatively, morphine consumption, side effects from morphine, and patient satisfaction were analyzed. …”
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Post operatory analgesia in caesarean surgery. by Bárbara Lucía Cabezas Poblet, Guyen Cuellar Chang, Rolando T. Espín González, María Antonia Cabezas Poblet

“…<strong><br />Conclusion: </strong>The administration of peridural liophilized morphine in elective caesarean sections is a reliable, sure and useful method in our environment.…”
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Psychotropes et hystérie à la Salpêtrière, le cas de Célina Marcil (1870-1879) by Zoë Dubus

“…In order to relieve her and to keep the ward calm, the hospital’s alienists were in the habit of generously providing sedatives such as ether or morphine to their patients. Her doctors therefore administered high doses of psychotropic drugs which in fact exacerbated her erotic delusions, meticulously transcribed in her case study. …”
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Role of bilevel erector spinae with high thoracic block vs conventional unilevel block in analgesia and reduction of pain in axilla in breast cancer surgeries: a randomized control... by Walaa Y. Elsabeeny, Reham M. Fahmy, Fatma H. Elshamy, Nahla N. Shehab, Sayed M. Abed, Walid S. Taha, Mostafa A. Ibrahim, Ahmed F. Gad

“…The primary outcome was total postoperative morphine consumption. Results:. Total postoperative morphine consumption was higher for the control group compared with the bilevel and unilevel groups (5.5 ± 1.8 vs 3.0 ± 0.0 and 4.3 ± 1.6 mg, P = 0.038). …”
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New methods of treatment for severe and moderate postoperative pain syndrome in patients with cancer by D.V. Dmytriiev, M.M. Barsa

“…After 48, 96, and 120 hours, pain levels did not differ between the groups. Morphine consumption differed significantly between the experimental and control groups on the first postoperative day (0 [0; 10] mg vs. 10.0 [0; 10] mg, respectively, p < 0.05). …”
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Comparison of the Postoperative Analgesic Effects between Ultrasound-Guided Transmuscular Quadratus Lumborum Block and Thoracic Paravertebral Block in Laparoscopic Partial Nephrect... by Jin Wang, Xulei Cui, Liying Ren, Xu Li, Yuelun Zhang, Yi Xie, Zhigang Ji, Yuguang Huang

“…The postoperative 48-hour cumulative morphine consumption was 10.60 ± 5.28 mg in the TMQLB group and 6.40 ± 3.40 mg in the PVB group. …”
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Peritoneal Nebulization of Ropivacaine during Laparoscopic Cholecystectomy: Dose Finding and Pharmacokinetic Study by Massimo Allegri, Martina Ornaghi, Catherine E. Ferland, Dario Bugada, Yash Meghani, Serena Calcinati, Manuela De Gregori, Federica Lovisari, Krishnaprabha Radhakrishnan, Maria Cusato, Stefano Scalia Catenacci, Marta Somaini, Guido Fanelli, Pablo Ingelmo

“…Nebulization of 50 mg of ropivacaine had the same effect of 100 or 150 mg in terms of postoperative morphine consumption, shoulder pain, postoperative nausea and vomiting, activity resumption, and hospital discharge timing (>0.05). …”
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Analgesic Efficacy of Intravenous Ibuprofen in the Treatment of Postoperative Acute Pain: A Phase III Multicenter Randomized Placebo-ControlledDouble-Blind Clinical Trial by Hong-Su Zhou, Ting-Ting Li, Yu Pi, Ting-Hua Wang, Fei Liu, Liu-Lin Xiong

“…Intermittent IV administration of ibuprofen 400 mg or 800 mg within 24 h after surgery in patients undergoing abdominal and orthopedic surgery significantly decreased morphine consumption and relieved pain, without increasing the incidence of AEs.…”
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Minimum effective concentration 90 (EC90) of ropivacaine for Femoral nerve block: A biased-coin up-and-down sequential method study by Ahmed M. Taha, Manjusha Mohanan, Sebastian Orduna, Ahmed F. Alalwi, Mohamed I. Badr, Ahmed M. Abd-Elmaksoud

“…The quadriceps motor power and morphine requirement were also recorded. Results: The recommended analgesic ropivacaine EC90 was 0.05% w/v. …”
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