Artemisia dracunculus essential oil: phytochemical study, pre-treatment and co-treatment effects on morphine withdrawal syndrome by Zahra Lorigooini, Fatemeh Heibati, Seyyed Matin Ahmadi, Sareh Mohammadi, Mahmoud Rafieian-Kopaei

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The Effects of Preoperative Oral Pregabalin and Perioperative Intravenous Lidocaine Infusion on Postoperative Morphine Requirement in Patients Undergoing Laparatomy by Senniye Ulgen Zengin, Ayten Saracoglu, Zeynep Eti, Tumay Umuroglu, Fevzi Yilmaz Gogus

“…OBJECTIVES: To evaluate and compare the effects of preoperative oral pregabalin and perioperative intravenous lidocaine infusion on postoperative morphine requirement, adverse effects, patients’ satisfaction, mobilization, time to first defecation and time to discharge in patients undergoing laparotomy.…”
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Rapid and easy determination of morphine in chafing dish condiments with colloidal gold labeling based lateral flow strips by Wei Chen, Xin-ni Li, Qian Wu, Li Yao, Jianguo Xu

“…In this research, a rapid, simple, and convenient method based on the classic immunochromatographic lateral flow strip (LFS) with gold nanoparticles (GNPs) labeling was developed for easy monitoring of morphine (MOP), an effective component of poppy shell. …”
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Disruption of the CRF1 receptor eliminates morphine-induced sociability deficits and firing of oxytocinergic neurons in male mice by Alessandro Piccin, Anne-Emilie Allain, Jérôme M Baufreton, Sandrine S Bertrand, Angelo Contarino

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Codeine 3-O-demethylase catalyzed biotransformation of morphinan alkaloids in Escherichia coli: site directed mutagenesis of terminal residues improves enzyme expression, stability... by Garrick W. K. Spencer, Xu Li, Kenny W. L. Lam, George Mutch, Fiona H. Fry, Sally L. Gras

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Effect of Nebulized Morphine on Dyspnea of Mustard Gas-Exposed Patients: A Double-Blind Randomized Clinical Trial Study by Majid Shohrati, Mostafa Ghanei, Asghar Amini Harandi, Soniya Foroghi, Ali Amini Harandi

“…We designed this study to evaluate effectiveness of nebulized morphine in such patients. Materials and Methods. In a double-blind clinical trial study, 40 patients with documented history of exposure to SM were allocated to two groups: group 1 who received 1 mg morphine sulfate diluted by 4 cc normal saline 0.5% using nebulizer once daily for 5 days and group 2 serving as control who received normal saline as placebo. …”
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Protocol to study the role of medial entorhinal cortex-basolateral amygdala circuit in context-induced retrieval of morphine withdrawal memory in mice by Yali Fu, Ting Ye, Ming Chen, Bin Lai, Ping Zheng

“…Summary: The medial entorhinal cortex (MEC) is crucial for context memory, yet its role in context-induced retrieval of morphine withdrawal memory remains to be investigated. …”
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Comparison of Clinical Efficacy of Intravenous Acetaminophen with Intravenous Morphine in Acute Renal Colic: A Randomized, Double-Blind, Controlled Trial by Kambiz Masoumi, Arash Forouzan, Ali Asgari Darian, Maryam Feli, Hassan Barzegari, Ali Khavanin

“…Then, one gram of intravenous acetaminophen or 0.1 mg/kg morphine was infused in 100 mL normal saline to either acetaminophen or morphine group. …”
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Morphine in Combination with Ketamine Improves Cervical Cancer Pain and Suppresses Immune Function via the JAK3/STAT5 Pathway by Yurong Jiang, Tong Li, Yi Qian, Xiaoming Zuo, Jinmei Liu

“…The role of ketamine as an adjuvant for morphine in the treatment of cancer pain and immune functions has been confirmed. …”
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Intravenous Oxycodone versus Intravenous Morphine in Cancer Pain: A Randomized, Open-Label, Parallel-Group, Active-Control Study by Kyung-Hee Lee, Jung-Hun Kang, Ho-Suk Oh, Moon-Ki Choi, Byoung-Yong Shim, Young-Jun Eum, Hye-Jeong Park, Jin-Hyong Kang

“…To compare efficacy and safety of intravenous continuous infusion of oxycodone with morphine in patients with cancer pain. Methods. A 5-day, randomized, open-label, exploratory study at 6 sites in the Republic of Korea. …”
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Deep brain stimulation of the anterior cingulate cortex reduces opioid addiction in preclinical studies by Mahdi Fatemizadeh, Esmail Riahi, Gholamreza Hassanzadeh, Anahita Torkaman-Boutorabi, Forough Radfar, Maryam Farahmandfar

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Jack London and White Fang: a lost struggle by Zilberstein, Gleb, Zilberstein, Svetlana, Rocco, Richard M., Righetti, Pier Giorgio

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Cocktail of Ropivacaine, Morphine, and Diprospan Reduces Pain and Prolongs Analgesic Effects after Total Knee Arthroplasty: A Prospective Randomized Controlled Trial by Zhenyu Luo, Weinan Zeng, Xi Chen, Qiang Xiao, Anjing Chen, Jiali Chen, Haoyang Wang, Zongke Zhou

“…Group B (LIA group, 50 patients) received an LIA cocktail of ropivacaine, morphine, and Diprospan (80 ml, 0.25% ropivacaine, 0.125 mg/ml morphine, and 62.5 μg/ml compound betamethasone). …”
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Assessing the Subjective and Physiological Effects of Intranasally Administered Crushed Extended-Release Morphine Formulations with and without a Sequestered Naltrexone Core in Recreational Opioid Users by Beatrice Setnik, Veeraindar Goli, Naama Levy-Cooperman, Catherine Mills, Megan Shram, Ira Smith

“…OBJECTIVE: To evaluate the pharmacodynamic (PD) effects of morphine sulfate and naltrexone hydrochloride extended-release (MSN) capsules compared with controlled-release morphine sulfate (MS) and placebo when crushed and administered intranasally.…”
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Perioperative Intravenous Patient-Controlled Analgesic Efficacy of Morphine with Combined Nefopam and Parecoxib versus Parecoxib in Gynecologic Surgery: A Randomized, Double-Blind Study by Varinee Lekprasert, Lapuskorn Yapanan, Wichai Ittichaikulthol, Rungrawan Buachai, Phimol Soisod, Areepan Sophonsritsuk

“…Intravenous patient-controlled analgesia with morphine was given for breakthrough pain within 24 h. …”
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Is a Single Low Dose of Intrathecal Morphine a Useful Adjunct to Patient-Controlled Analgesia for Postoperative Pain Control Following Lumbar Spine Surgery?... by David Yen, Kim Turner, David Mark

“…BACKGROUND: Several studies addressing intrathecal morphine (ITM) use following spine surgery have been published either involving the pediatric population, using mid- to high-dose ITM, or not in conjunction with morphine patient-controlled analgesia (PCA).…”
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Intranasal Pharmacokinetics of Morphine ARER, a Novel Abuse-Deterrent Formulation: Results from a Randomized, Double-Blind, Four-Way Crossover Study in Nondependent, Opioid-Experienced Subjects by Lynn R. Webster, Carmela Pantaleon, Matthew Iverson, Michael D. Smith, Eric R. Kinzler, Stefan Aigner

“…To investigate the pharmacokinetics (PK) of Morphine ARER, an extended-release (ER), abuse-deterrent formulation of morphine sulfate after oral and intranasal administration. …”
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Modification of Gene Expression Involved in Alkaloid Production in Opium Poppy by VIGS Combined With Pretreatment of Macerozyme Enzyme by Deniz Ece Özcan, Deniz Köm, Ozan Doğan, Semiha Erişen, Selma Onarici

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Continuous Intra-Incisional Bupivacaine for Postoperative Analgesia after Hip Nailing Surgery: A Randomized Clinical Trial by Arash Farbood, Sanaz Abbasi, Naeimehossadat Asmarian, Mahsa Banifatemi, Vida Naderi-boldaji, Zeinabsadat Fattahi Saravi

“…In the ward, all control group patients used the PCA morphine pump, while only 54% of the bupivacaine group self-administered morphine through the pump, with a significantly lower total morphine consumption (1 (0–2) vs. 10 (5–14) mg, P<0.001). …”
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Effects of Addition of Preoperative Intravenous Ibuprofen to Pregabalin on Postoperative Pain in Posterior Lumbar Interbody Fusion Surgery by Hüseyin Ulaş Pınar, Ömer Karaca, Fatma Karakoç, Rafi Doğan

“…Postoperative analgesia was obtained by morphine patient controlled analgesia (PCA) and 1 g i.v. paracetamol every six hours. …”
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