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Oxygenase Enzyme Activity and Compound Profile in Hydrocarbon Bioremediation by Pseudomonas aeruginosa and Rhodococcus erythropolis Consortium
Published 2023-12-01“…The results showed that the monooxygenase enzyme has activity between 0.257 and 3.859 U/mL. …”
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22
3-Hydroxyanthranic acid inhibits growth of oral squamous carcinoma cells through growth arrest and DNA damage inducible alpha
Published 2025-02-01“…Higher expression of kynurenine 3-monooxygenase (KMO) and kynureninase (KYNU), which can increase the content of 3-HAA, was associated with poorer prognosis of OSCC patients. …”
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23
Identification and functional characterization of AsWRKY9, a WRKY transcription factor modulating alliin biosynthesis in garlic (Allium sativum L.)
Published 2025-01-01“…In transgenic callus overexpressing AsWRKY9, the transcription level of the key enzyme flavin-containing monooxygenase gene (AsFMO1) significantly higher, as did its enzymatic activity compared with the control. …”
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Combined induction by Cu(II) and veratrole enhances the degradation of high molecular weight polyaromatic hydrocarbons by Fusarium dlaminii ZH-H2
Published 2025-02-01“…These included cytochrome P450 monooxygenase (EC:1.–.-.-) and downstream PAH converting enzymes such as aldehyde dehydrogenase (EC:1.2.1.3), NADP-dependent ethanol dehydrogenase (EC:1.1.1.2), ethanol dehydrogenase (EC:1.1.1.156], tryptophan 2,3 dioxygenase (EC:1.13.11.52), gentisate 1,2-dioxygenase (EC:1.13.11.5), salicylate hydroxylase (EC:.14.13.1) β-hexokinase (EC:3.2.1.52), and glutathione transferase (EC: 2.5.1.18). …”
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Diversity and distribution of nitrifying bacteria play an important role in the nitrogen cycle in mangrove sediments
Published 2024-10-01“…In carrying out changes in nitrogen compounds, nitrifying bacteria use functional genes from different steps of the nitrification process, such as nitrogenase, ammonia monooxygenase subunit A, nitrite oxidoreductase alpha subunit, nitrate reductase alpha chain, nitrite reductase, nitric oxide reductase, nitrous oxide reductase, hydrazine synthase, hydrazine oxidoreductase and hydroxylamine oxidoreductase genes. …”
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Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress...
Published 2025-01-01“…Plasma metabolite levels are generally consistent with those of urine: antioxidant KYNs, 5-hydroxyindoleacetic acid, and indole-3-acetic acid levels were lower; enzyme activities in KATs, kynureninase, and monoamine oxidase/aldehyde dehydrogenase were lower, but kynurenine 3-monooxygenase was higher; and oxidative stress and excitotoxicity indices were higher. …”
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27
Epithelial NSD2 maintains FMO‐mediated taurine biosynthesis to prevent intestinal barrier disruption
Published 2024-12-01“…Mechanistically, NSD2 loss led to downregulation of H3K36me2 and flavin‐containing monooxygenase (FMO) (taurine‐synthesis enzyme) mRNA, resulting in decreased taurine biosynthesis in IECs. …”
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28
Transcriptomic resources for Bagrada hilaris (Burmeister), a widespread invasive pest of Brassicales.
Published 2024-01-01“…Three gene families involved in xenobiotic detoxification-glutathione S-transferases, carboxylesterases and cytochrome P450 monooxygenases-were phylogenetically characterized. These data were also qualitatively compared with previously published results for two closely related pentatomid species-the brown marmorated stink bug, Halyomorpha halys (Stål), and the harlequin bug, Murgantia histrionica (Hahn)-to elucidate shared enzymatic components of terpene-based sex pheromone biosynthetic pathways. …”
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29
Accelerated aging modulates the toxicological properties of the diazo tattoo pigment PO13
Published 2025-01-01“…DCBP was found to activate CYP450 monooxygenases known to be involved in the metabolism of xenobiotics. …”
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Enzymatic functionalization of bacterial nanocellulose: current approaches and future prospects
Published 2025-02-01“…., utilizing a laccase/TEMPO catalytic system or lytic polysaccharide monooxygenases) and esterification catalyzed by lipases; or an indirect procedure involving the application of bacterial nanocellulose as a matrix for enzyme immobilization (e.g., laccase, glucose oxidase, horseradish peroxidase, lysozyme, bromelain, lipase, papain), thus creating a specific catalytic system. …”
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31
Saprotrophic Wood Decay Ability and Plant Cell Wall Degrading Enzyme System of the White Rot Fungus <i>Crucibulum laeve</i>: Secretome, Metabolome and Genome Investigations
Published 2024-12-01“…<i>C. laeve</i> produces a unique repertoire of proteins for the saccharification of the plant biomass, including predominantly oxidative enzymes such as laccases (family AA1_1 CAZymes), GMC oxidoreductases (family AA3_2 CAZymes), FAD-oligosaccharide oxidase (family AA7 CAZymes) and lytic polysaccharide monooxygenases (family LPMO X325), as well as accompanying acetyl esterases and loosenine-like expansins. …”
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Differential detoxification enzyme profiles in C-corn strain and R-rice strain of Spodoptera frugiperda by comparative genomic analysis: insights into host adaptation
Published 2025-01-01“…Results A total of 1,995 detoxification-related genes, including cytochrome P450 monooxygenases (CYPs), carboxylesterases (COEs), glutathione S-transferases (GSTs), UDP-glucuronosyltransferases (UGTs), and ATP-binding cassette transporters (ABCs), were identified across the genus Spodoptera, including S. littoralis, S. litura, S. picta, S. exigua, and both FAW strains. …”
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THE BIOSYNTHESIS REGULATION OF POTATO STEROIDAL GLYCOALKALOIDS
Published 2018-03-01“…As a promising target for reducing SGA levels in tubers, the genes encoding PGA enzymes (belonging to the CYP72 subfamily cytochrome-P450-dependent monooxygenases catalyzing the conversion of hydrocholesterol to trihydrocholesterol) and SGT (SGA glycosyltransferases that catalyze the conversion of solanidine to its toxic glycosylated derivatives α-solanine and α-chaconine) are considered. …”
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A common mechanism of detoxification for lambda-cyhalothrin and abamectin in Cydia pomonella
Published 2023-11-01“…To validate whether similar mechanisms were involved in the detoxification process of lambda-cyhalothrin (LCT) and abamectin (AM) at sublethal doses (specifically LD10 and LD30), cytochrome P450 monooxygenases (P450), glutathione S-transferases (GST), and carboxylesterases (CarE) activities were evaluated after insecticides exposure; synergistic experiments were conducted using piperonyl butoxide (PBO), diethyl maleate (DEM), and triphenyl phosphate (TPP) as inhibitors of P450, GST, and CarE respectively. …”
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First genome-scale insights into the virulence of the snow mold causal fungus Microdochium nivale
Published 2023-01-01“…In addition to disclosing plant-metabolite-upregulated M. nivale functional gene groups (including those related to host plant protein destruction and amino acid metabolism, xenobiotic detoxication (including phytoalexins benzoxazinoids), cellulose destruction (cellulose monooxygenases), iron transport, etc.), the performed analysis pointed to a crucial role of host plant lipid destruction and fungal lipid metabolism modulation in plant-M. nivale interactions.…”
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