Identification of mitophagy-related biomarkers and immune infiltration in polycystic ovarian syndrome by bioinformatic study by Hongjuan Ye, Xicheng Wang, Zhiying He

“…Specifically, the hub gene GRN showed a positive correlation with monocytes and plasmacytoid dendritic cells, while hub gene NAPA was negatively correlated with gamma delta T cell. …”
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Single-cell transcriptome analysis reveals cellular reprogramming and changes of immune cell subsets following tetramethylpyrazine treatment in LPS-induced acute lung injury by Mingyan Wu, Shanmei Wang, Xiaolan Chen, Li Shen, Jurong Ding, Hongbin Jiang

“…However, TMP treatment in the LPS-induced ALI model significantly increased follicular helper T cells and reduced CD8+ naive T cells, Vcan-positive monocytes and Siva-positive NK cells. In addition, TMP treatment increased the number of basal epithelial cells and lymphatic endothelial cells (LECs), indicating its protective effects on these cell types. …”
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Blood leukocyte-based clusters in patients with traumatic brain injury by Ruoran Wang, Jianguo Xu, Min He

“…Blood levels of neutrophils, lymphocytes, monocytes, basophils, and eosinophils were collected by analyzing the first blood sample within 24 h since admission. …”
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Measurement of Several Hematological and Serological Parameters in Patients with Scabies by Mariam Y. Al-Fadhly, Wasan A. Al-Marsomy, Hiba H. Maqdasi .

“…There were also significant differences at the 0.001 level between the two groups of patients and the control group for white blood cells (WBC), lymphocytes, neutrophils, eosinophils, monocytes, and basophils. These were (11.09±0.20, 7.50 ±0.16), (5.05±0.16, 2.27 ±0.06), (8.23±0.10, 3.75±0.11), (0.828±0.7, 0.415±0.03), (0.498±0.02, 0.459±0.03), and (0.329±0.02, 0.102 ± 0.01), respectively. …”
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Investigation of the healing effects of Afyon Province hot spring waters on experimentally-induced fatty liver in mice by Bülent Elitok, Ibrahim Kişlalioğlu, Yavuz Ulusoy, Bahadır Kilinç

“…On day 21 of the experiment, the animals of the experimental group demonstrated a significant (p < 0.05) decrease in the total number of leukocytes, neutrophils, monocytes, as well as in the levels of aspartate aminostatesferase, alanine aminopenesferase, gamma-glutamyltransferase, low-density lipoproteins, total cholesterol, triglycerides. …”
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Exploration and Verification of Prognostic Value of Endothelial Cells in Glioblastoma by Hengchao MA, Yuyang LIU, Jun XU, Bingyan TAO, Jun ZHANG

“…Seven groups of cells were obtained after GBM single-cell sequencing analysis, including AC-like tumor cells, endothelial cells, monocytes/macrophages, NB-like tumor cells, neurons, OC-like tumor cells, and OPC-like tumor cells. …”
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CD226 Deficiency Alleviates Murine Allergic Rhinitis by Suppressing Group 2 Innate Lymphoid Cell Responses by Yang Xie, Yuan Zhang, Tianxiao Zhu, Jingchang Ma, Chujun Duan, Lu Yang, Tingting Wang, Ran Zhuang, Ka Bian, Lianjun Lu

“…CD226 is a costimulatory molecule associated with inflammatory response and is mainly expressed on T cells, natural killer cells, and monocytes. This study is aimed at elucidating the role of CD226 in allergic inflammatory responses in murine AR using global and CD4+ T cell-specific Cd226 knockout (KO) mice. …”
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The Prognostic Significance of TRs in Hepatocellular Carcinoma: Insights from TCGA and GEO Databases by Hao Zhou, Weijie Wang, Ruopeng Liang, Rongtao Zhu, Jiahui Cao, Chenguang Sun, Yuling Sun

“…Additionally, single-cell RNA sequencing revealed that THRB was primarily expressed in CD16+ monocytes within tumor tissues and was associated with a poor OS rate. …”
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Exploring the functional and immune landscape of E-β thalassemia patients through RNA sequencing of peripheral blood mononuclear cells by Nibedita Mitra, Prosanto Chowdhury, Anupam Basu

“…Deconvolution of the RNA-seq data revealed lower abundances of CD4 T cells and monocytes in thalassemia patients.Thus, immune-modulating drugs could be explored as alternative therapeutic options for the management of thalassemia.…”
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SIGLEC11 promotes M2 macrophage polarization through AKT–mTOR signaling and facilitates the progression of gastric cancer by Chen Li, Yang Lu, Yihao Liu, Minmin Shi, Zhenggang Zhu, Jingxin Yin, Qimeng Shi, Da Fu, Zhenqiang Wang

“…Our results showed that SIGLEC11 was predominantly expressed in monocytes and macrophages and selectively upregulated in tumor-associated macrophages. …”
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The profiles of immunosuppressive microenvironment in the Lauren intestinal-type gastric adenocarcinoma by Qingyuan Wang, Jia Chen, Yaohui Wang, Xiang Li, Xiaochun Ping, Jiajia Shen, Sheng Yang, Lizong Shen

“…Furthermore, TNFRSF12A + cancer-associated fibroblasts (CAFs), CTSB + macrophages, and SOD2 + monocytes were found to be involved in maintaining the immunosuppressive milieu. …”
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Anti-inflammatory and antioxidant properties of oleuropein in human keratinocytes characterized by bottom-up proteomics by Huifang Li, Ni Deng, Jiayi Yang, Yang Zhao, Xiaoxuan Jin, Ang Cai, Navindra P. Seeram, Hang Ma, Dongli Li, Huilan Yang, Chang Liu, Chang Liu

“…In a cell-based inflammasome model with human monocytes (THP-1 cells), oleuropein (12–200 µM) reduced proinflammatory cytokine interleukin (IL)-6 by 38.8%–45.5%, respectively. …”
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Haematobiochemical alterations and lesion characterization induced by haemonchosis in slaughtered sheep at Gondar ELFORA abattoir, Ethiopia by Birhan Anagaw Malede, Mersha Chanie Kebede, Asnakew Mulaw Berihun, Muluken Yayeh Mekonnen, Mohammed Yesuf, Tadegegn Mitiku, Mastewal Birhan, Ambaye Kenubih, Abraham Belete Temesgen

“…However, white blood cells, monocytes, neutrophils, and eosinophils were significantly higher in the infected group. …”
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Single-cell transcriptomics identify a novel macrophage population associated with bone invasion in pituitary neuroendocrine tumors by Xinzhi Wu, Xueshuai Han, Haibo Zhu, Mingxuan Li, Lei Gong, Sicheng Jing, Weiyan Xie, Zhaoqi Liu, Chuzhong Li, Yazhuo Zhang

“…TNF-α+ TAMs, in turn, communicate with CD14 + monocytes to promote their differentiation into osteoclasts and leading to bone invasion. …”
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Downregulation of MerTK in circulating T cells of patients with non-proliferative diabetic retinopathy by Shimiao Bu, Shimiao Bu, Jiang-Yue Ling, Jiang-Yue Ling, Xiaojun Wu, Xiaojun Wu, Liting Zhang, Liting Zhang, Xiangyu Shi, Lang Huang, Zheng Zhao, Ying Yang, Zongqin Xiang, Yong U. Liu, Yong U. Liu, Yufeng Liu, Yuehong Zhang, Yuehong Zhang

“…Through flow cytometry, we assessed the protein levels and cellular distribution of MerTK, finding a predominant expression in monocytes and myeloid-derived suppressor cells (MDSCs), with a marked reduction in CD4+ and CD8+ T cells, as well as in natural killer T (NKT) cells. …”
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Single-cell RNA sequencing of circulating immune cells supports inhibition of TNFAIP3 and NFKBIA translation as psoriatic arthritis biomarkers by Ameth N. Garrido, Rohan Machhar, Omar F. Cruz-Correa, Darshini Ganatra, Sarah Q. Crome, Sarah Q. Crome, Joan Wither, Joan Wither, Joan Wither, Igor Jurisica, Igor Jurisica, Igor Jurisica, Dafna D. Gladman, Dafna D. Gladman, Dafna D. Gladman

“…Differentially expressed genes (DEGs) identified through scRNA-seq were validated on classical monocytes, and CD4+ and CD8+ T cell subsets derived from an independent cohort of patients using the NanoString nCounter® platform. …”
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Early and delayed STAT1-dependent responses drive local trained immunity of macrophages in the spleen by Aryeh Solomon, Noa Bossel Ben-Moshe, Dotan Hoffman, Sébastien Trzebanski, Dror Yehezkel, Leia Vainman, Mihai G Netea, Roi Avraham

“…Early inhibition of STAT1 activation, using specific JAK-STAT inhibitors, reduces both RPM loss and recruitment of trained monocytes. Our study suggests a temporal window soon after BCG vaccination, in which STAT1-dependent activation of long-lived resident cells in the tissue mediates localized protection.…”
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Single cell and spatial analysis of immune-hot and immune-cold tumours identifies fibroblast subtypes associated with distinct immunological niches and positive immunotherapy respo... by Benjamin H. Jenkins, Ian Tracy, Maria Fernanda S. D. Rodrigues, Melanie J. L. Smith, Begoña R. Martinez, Mark Edmond, Sangeetha Mahadevan, Anjali Rao, Hailing Zong, Kai Liu, Abhishek Aggarwal, Li Li, Lauri Diehl, Emma V. King, Jamie G. Bates, Christopher J. Hanley, Gareth J. Thomas

“…IL-11 + iCAF were spatially associated with inflammatory monocytes and regulated in vitro through synergistic activation of canonical NF-κB signalling by IL-1β and TNF-α. …”
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The SIRT5-JIP4 interaction promotes osteoclastogenesis by modulating RANKL-induced signaling transduction by Kecheng Zhu, Chunxiang Sheng, Linlin Zhang, Yuying Yang, Xiaojing Chen, Tao Jiang, Jiaxi Song, Deng Zhang, Xiao Wang, Hongyan Zhao, Lihao Sun, Libin Zhou, Bei Tao, Jianmin Liu

“…Mice with global or conditional monocytic lineage knockout of SIRT5 had increased bone mass and reduced osteoclast numbers. …”
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Targeting immune cellular populations and transcription factors: unraveling the therapeutic potential of JQF for NAFLD by Lijuan Zhou, Jingyi Zhao, Kaile Ma, Rui Hao, Chensi Yao, Xiaowen Gou, Chuanxi Tian, Li Wan, Min Li, Xiaolin Tong

“…Furthermore, significant changes were observed in the immune cells including monocytes, macrophages, and T cells in the livers of NAFLD mice. …”
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