lncRNA HOTTIP Recruits EZH2 to Inhibit PTEN Expression and Participates in IM Resistance in Chronic Myeloid Leukemia by Jing Liu, Lin Yang, Xiaojun Liu, Lu Liu, Menghan Liu, Xuefeng Feng, Jianmin Luo

“…Seventy-one cases of bone marrow monocytes diagnosed with CML in the Second Hospital of Hebei Medical University from 2018 to 2021 were selected. …”
Get full text

Common biomarkers of idiopathic pulmonary fibrosis and systemic sclerosis based on WGCNA and machine learning by Ning Shan, Yu Shang, Yaowu He, Zhe Wen, Shangwei Ning, Hong Chen

“…Single-cell RNA sequencing (sc-RNAseq) revealed a significant difference in CCL2 expression in alveolar epithelial type 1/2 cells, mast cells, ciliated cells, club cells, fibroblasts, M1/M2 macrophages, monocytes and plasma cells between IPF patients and healthy donors. …”
Get full text

The role of histone lactylation genes in hepatocellular carcinoma prognostic models and their immune cell infiltration features: a comprehensive analysis of single-cell, spatial tr... by Shanjie Luan

“…Mendelian randomization results showed that TBNK and monocytes were the main risk factors. qRT-PCR validation results indicated that the expression of multiple genes in Huh7 cells was significantly higher than in LO2 cells. …”
Get full text

Construction of a Cuprotosis-Related Gene-Based Model to Improve the Prognostic Evaluation of Patients with Gastric Cancer by Chunyan Han, Kai Zhang, XinKai Mo

“…Results. The plasma cells, monocytes, and mast cells in GC tissue were significantly less than those in adjacent tissue (p<0.05), while T cell CD4 memory activated macrophage M0, macrophage M1, and macrophages in GC tissue. …”
Get full text

Development of Asthma Mouse Model By Dermal Sensitization by Isameldin Abdalla, Amir A. Bashir

“…In the TDI group, a significant increase was seen in the BALF, neutrophils, lymphocytes, and basophils; the increase in eosinophils and monocytes was nonsignificant. Besides, lung-related histopathological changes in the TDI group were hyperemia, leukocytic infiltration, thickening of bronchoalveolar walls, and damage of respiratory epithelium. …”
Get full text

Effectiveness of kepok banana stem extract (Musa Acuminata) on the immune response of catfish (Clarias gariepinus) infected with Aeromonas hydrophila by Hany Handajani, Anis Zubaidah, Dina Izzah Kamila

“…Leukocyte differential observation showed that kepok banana stem extract had a significant effect on eosinophils, lymphocytes, and neutrophils but no significant effect on monocytes. In analyzing fish blood, the optimal values were 7.64±0.190a cells/mm3 for leukocytes, 3.60±0.116d cells/mm3 for erythrocytes, 65±6.028b mg/dl for glucose, 74.67±0.577d% for lymphocytes, 5.67±0.577a% for neutrophils, and 0±0a% for eosinophils. …”
Get full text

Sex-Related Differences in Hematological Parameters and Organosomatic Indices of Oreochromis niloticus Exposed to Aflatoxin B1 Diet by Esther Marijani, Johnson Nasimolo, Emmanuel Kigadye, Gbemenou Joselin Benoit Gnonlonfin, Sheila Okoth

“…No sex-related differences in RBC, WBC, lymphocytes, monocytes, and neutrophils levels were observed. However, hemoglobin and hematocrit values for female O. niloticus were significantly lower than those for male O. niloticus. …”
Get full text

Cardiac-Restricted IGF-1Ea Overexpression Reduces the Early Accumulation of Inflammatory Myeloid Cells and Mediates Expression of Extracellular Matrix Remodelling Genes after Myoca... by Enrique Gallego-Colon, Robert D. Sampson, Susanne Sattler, Michael D. Schneider, Nadia Rosenthal, Joanne Tonkin

“…Infiltration of inflammatory cells, which direct the remodelling process, was also altered; in particular there was a notable reduction in inflammatory Ly6C+ monocytes at day 3 and an increase in anti-inflammatory CD206+ macrophages at day 7. …”
Get full text

In Vivo Imaging of Peripheral Benzodiazepine Receptors in Mouse Lungs: A Biomarker of Inflammation by Matthew J. Hardwick, Ming-Kai Chen, Kwamena Baidoo, Martin G. Pomper, Tomás R. Guilarte

“…Peripheral benzodiazepine receptors (PBR) are present in monocytes and neutrophils as well as in lung tissue. …”
Get full text

ANORECTAL PATHOLOGIES IN THE COURSE OF ACUTE LEUKAEMIAS: PREDICTIVE PARAMETERS by Fatma Yılmaz, Bugra Saglam, Ufuk Gorduk, Ugur Kalan, Hacer Berna Afacan Öztürk, Ahmet Kursad Gunes, Murat Albayrak

“…In the group of patients with anorectal pathology, WBC, lymphocytes, monocytes, LDH were significantly (p<0.05) higher and platelets, MPV, PCT were significantly (p<0.05) lower. …”
Get full text

Integrated Bioinformatics Identifies FREM1 as a Diagnostic Gene Signature for Heart Failure by Chenyang Jiang, Weidong Jiang

“…Immune cell subtypes of tissue specimens found T cell CD8, mast cell resting, T cell CD4 memory resting, T cell regulation (Tregs), monocytes, macrophages M2, T cell CD4 naive, macrophages M0, and neutrophils are associated with HF. …”
Get full text

The Diagnostic and Predictive Significance of Immune-Related Genes and Immune Characteristics in the Occurrence and Progression of IgA Nephropathy by Jian-Bo Qing, Wen-Zhu Song, Chang-Qun Li, Ya-Feng Li

“…A higher macrophage ratio and lower CD4+ T cell ratio in IgAN compared to controls were observed, and the correlation between macrophages and monocytes in the glomeruli of IgAN patients was inverse compared to controls. …”
Get full text

To describe the subsets of malignant epithelial cells in gastric cancer, their developmental trajectories and drug resistance characteristics by Tingting Xu, Tianying Zhang, Yan Sun, Sijia Wu

“…This study employed single-cell RNA sequencing, using the 10 × Genomics platform, to analyze 262,532 cells from gastric cancer samples, identifying 32 distinct clusters and 10 major cell types, including immune cells (e.g., T cells, monocytes) and epithelial subpopulations. Among 27 epithelial subgroups, five malignant subpopulations were identified, each defined by unique marker gene expressions and playing diverse roles in tumor progression. …”
Get full text

Some haematological values in the healthy hamdani (hareki-harki) sheep by Mursayettin Eksen, Z. Tevfik Ağaoğlu, Ercan Keskin

“…On the other hand, the lymphocytes, neutrophils, monocytes and eosin ophils were determined as 53.6 %, 39.0 %, 4.6 % and 2.8 % in the female sheep, whereas these values found to be 49.2%, 44.0%, 4.4% and 2.4% in male sheep respectively.…”
Get full text

Risk Factors Analysis of Cutaneous Adverse Drug Reactions Caused by Targeted Therapy and Immunotherapy Drugs for Oncology and Establishment of a Prediction Model by Zimin Zhang, Mingyang Zhu, Weiwei Jiang

“…Nine risk factors were eventually identified: age, treatment modality, cancer types, history of allergies, age‐corrected Charlson comorbidity index, percentage of eosinophils, absolute number of monocytes, Eastern Cooperative Oncology Group Performance Status, and C‐reactive protein. …”
Get full text

Design and Optimization of the Circulatory Cell-Driven Drug Delivery Platform by Pengyu Gao, Dan Zou, Ansha Zhao, Ping Yang

“…This review specifically covers (a) the properties of red blood cells, monocytes, macrophages, neutrophils, natural killer cells, T lymphocytes, and mesenchymal stem cells; (b) the loading strategies to balance cargo amounts and cell function balance; (c) the cascade strategies to improve cell-driven targeting delivery efficiency; and (d) the features and applications of cell membranes, artificial cells, and extracellular vesicles in cancer treatment.…”
Get full text

Therapeutic anti-inflammatory immune potentials of some seaweeds extracts on chemically induced liver injury in mice by Eman Bases, Mostafa M. El-Sheekh, Shimaa M. El Shafay, Rania El-shenody, Mohamed Nassef

“…Pre-treatment and post-treatment of P. pavonia and J. rubens extracts in CCL4/mice increased WBCs count and lymphocytes relative numbers and reduced the neutrophils and monocytes relative numbers. Pre-treatment and post-treatment of CCL4/mice with P. pavonia and J. rubens extracts significantly reduced the release amounts of pro-inflammatory cytokines TNF-α and IL-6 and significantly inhibited the increased CRP level. …”
Get full text

A systematic in vitro study of the effect of normoglycaemic and hyperglycaemic conditions on the biochemical and cellular interactions of clinically-available wound dressings with... by Shirin Saberianpour, Gianluca Melotto, Rachel Forss, Lucy Redhead, Susan Sandeman, Nadia Terrazzini, Dipak Sarker, Matteo Santin

“…Dressings presenting absorbent layers made of synthetic, non-woven fibres supported the adhesion of monocytes macrophages and stimulate the release of factors known to play a role in the chronic inflammation. …”
Get full text

Adipose-Derived Mesenchymal Stem Cells Promote M2 Macrophage Phenotype through Exosomes by June Seok Heo, Youjeong Choi, Hyun Ok Kim

“…In this study, adipose-derived MSCs (AdMSCs) and human peripheral blood monocytes (PBMCs) were isolated and cultured to examine the effects of MSC-induced macrophages (iMΦ) on inflammation and immune modulation. …”
Get full text

GGT5 Is an Independent Prognostic Biomarker in Stomach Adenocarcinoma by Yong Huang, HaiLang Zhou, Junwei Zou, Dong Wang

“…The high-expression GGT5 group had higher concentrations of M2 macrophages, T cell regulators, and monocytes, but the contents of plasma cells and M1 macrophages were higher in the low-expression GGT5 group. …”
Get full text