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641
Coinfections increase the risk of HIV acquisition, AIDS progression, and therapy and prophylaxis failure: a review
Published 2024-08-01“…The immunologic insults stimulate increased C–C chemokine receptor type 5 co-expression with a cluster of differentiation 4 on monocytes and T cells, which is required for HIV infection and replication. …”
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642
Ways to promote the efficiency of herpetic stomatitis treatment
Published 2023-06-01“…The drug suppresses the synthesis of the virus due to the structure of inosinic acid in the polyribosomes of the cell affected by the virus, and also helps to eliminate the deficiency or dysfunction of immunity that occurred in the case of herpetic stomatitis, it affects the activity of T-cytotoxic lymphocytes and natural killers, enhances the action of neutrophil granulocytes, chemotaxis and phagocytosis of monocytes and macrophages, increases the synthesis of interleukins IL-1 and IL-2, affects the number of Ig G immunoglobulins. …”
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643
Effects of Thyme Extract Oils (from Thymus vulgaris, Thymus zygis, and Thymus hyemalis) on Cytokine Production and Gene Expression of oxLDL-Stimulated THP-1-Macrophages
Published 2012-01-01“…As a cellular model of inflammation/atherogenesis, we use human macrophages derived from THP-1 monocytes and activated by oxidized LDLs. These cells were incubated with the thyme fraction oils, and the productions and gene expressions of the inflammatory mediators TNF-α, IL-1B, IL-6, and IL-10 were determined. …”
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644
Modulation of Synovial Fluid-Derived Mesenchymal Stem Cells by Intra-Articular and Intraosseous Platelet Rich Plasma Administration
Published 2016-01-01“…The presence in the SF of mesenchymal stem cells (MSCs), monocytes, and lymphocytes was determined and quantified by flow cytometry. …”
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645
Influence of physicochemical factors on the interaction of metallic nanoparticles with immune system cells
Published 2025-01-01“…This paper reviews the reported biological effects of MNPs on various immune cell types, including B and T lymphocytes, neutrophils, monocytes, macrophages, dendritic cells, natural killer cells, mast cells, basophils, and eosinophils.…”
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646
Molecular Prevalence and Identification of Ehrlichia canis and Anaplasma platys from Dogs in Nay Pyi Taw Area, Myanmar
Published 2021-01-01“…Ticks are vectors of different types of viruses, protozoans, and other microorganisms, which include Gram-negative prokaryotes of the genera Rickettsiales, Ehrlichia, Anaplasma, and Borrelia. Canine monocytic ehrlichiosis caused by Ehrlichia canis and canine cyclic thrombocytopenia caused by Anaplasma platys are of veterinary importance worldwide. …”
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647
Evolutionary conserved regulation of TFEB stability by the E3 ubiquitin ligase WWP2 modulates response to stress in vivo
Published 2025-02-01“…Finally, we found that WWP2 is required for TFEB-dependent host response in human monocytes-derived macrophages upon infection. Overall, our work has identified an evolutionarily conserved regulation of TFEB by WWP2 and highlighted its role in modulating stress response.…”
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648
Identification of Macrophage Genotype and Key Biological Pathways in Circulating Angiogenic Cell Transcriptome
Published 2019-01-01“…Genes and pathways of interest were further evaluated using qPCR comparing CACiv versus CD14+ monocytic cells. The CACiv transcriptome strongly related to tissue macrophages, and more specifically to regulatory M2c macrophages. …”
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649
Triple-negative breast cancer modifies the systemic immune landscape and alters neutrophil functionality
Published 2025-01-01“…Chemotherapy-naïve mTNBC patients showed increased classical monocytes and neutrophils. Transcriptional, proteomic, and functional analyses revealed that neutrophils in mTNBC exhibited enhanced migratory capacity, elevated granule proteins, and higher ROS production. …”
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650
Iodine activates NLRP3 inflammasomes in PBMCs of patients with autoimmune thyroiditis and regulates Th1 and Th17 cell differentiation
Published 2025-01-01“…Flow cytometry was employed to examine NLRP3 expression on CD14+ monocytes and Th1 and Th17 cell percentages in the groups. …”
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651
Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators
Published 2025-01-01“…Apheresis also led to a decrease in the proportion of monocytes, an increase in the proportion of T cells (n=29 patients with MS or NMOSD) and moderate transcriptome changes (nmax=4 MS patients). …”
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652
Macrophage Polarisation in the Tumour Microenvironment: Recent Research Advances and Therapeutic Potential of Different Macrophage Reprogramming
Published 2025-01-01“…Background Macrophages are a critical component of the innate immune system, derived from monocytes, with significant roles in anti-inflammatory and anti-tumour activities. …”
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653
The Transcriptional Network Structure of a Myeloid Cell: A Computational Approach
Published 2017-01-01“…Here, we built a transcription factor network for human monocytic THP-1 myeloid cells based on the experimentally curated FANTOM4 database where nodes are genes and the experimental interactions correspond to links. …”
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654
Serum Calprotectin Level in Type 2 Diabetic Patients with and without Diabetic Peripheral Neuropathy: A Comparison Study
Published 2024-12-01“…Calprotectin (CLP) is a heterodimer protein found in the membranes of monocytes and other inflammatory cells and the cytosol of neutrophils and released from them up to activation. …”
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655
TLR10 overexpression modulates immune response in A549 lung epithelial cells challenged with SARS-CoV-2 S and N proteins
Published 2025-01-01“…The results showed that overexpression of TLR10 in A549 lung epithelial cells, immunostimulated with SARS-CoV-2 proteins S and N mainly downregulated proinflammatory cytokines and interferons and affected gene expression in the cocultured THP-1 monocytes. Our results suggest that TLR10 could mediate the extent of SARS-CoV-2 infection by downregulating the release of inflammatory cytokines and chemokines such as CXCL10, IL6, IL8, and IFNβ. …”
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656
Role of Fractalkine/CX3CL1 and Its Receptor in the Pathogenesis of Inflammatory and Malignant Diseases with Emphasis on B Cell Malignancies
Published 2014-01-01“…The biological activities of CX3CL1 are mediated by CX3CR1, that is expressed on different cell types such as NK cells, CD14+ monocytes, cytotoxic effector T cells, B cells, neurons, microglia, smooth muscle cells, and tumor cells. …”
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657
HLA-G Dimers in the Prolongation of Kidney Allograft Survival
Published 2014-01-01“…Our study showed that a high level of HLA-G dimers in plasma and increased expression of the membrane-bound form of HLA-G on monocytes are associated with prolongation of kidney allograft survival. …”
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658
HFE-Related Hemochromatosis: The Haptoglobin 2-2 Type Has a Significant but Limited Influence on Phenotypic Expression of the Predominant p.C282Y Homozygous Genotype
Published 2009-01-01“…Hp2-2 favors endocytosis of hemoglobin iron in monocytes/macrophages, resulting in partial iron retention and increased intracellular ferritin levels. …”
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659
Human Liver Stem Cells Suppress T-Cell Proliferation, NK Activity, and Dendritic Cell Differentiation
Published 2016-01-01“…When tested on DC generation from monocytes, HLSCs were found to impair DC differentiation and DCs ability to induce T-cell proliferation through PGE2. …”
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660
Mononuclear Aluminum–Fluoride Ions, AlF<i><sub>x</sub></i><sup>(+/−)</sup>—Study of Plausible Frameworks of Complexes with Biomolecules and Their In Vitro Toxicity
Published 2025-01-01“…The effects of varying concentrations of fluoride, aluminum and AlF<i><sub>x</sub></i>—from micromolar to millimolar levels—on the viability and apoptosis rate of THP-1 monocytes were investigated using phosphate buffer solution as a culture media to simulate physiological conditions. …”
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