A randomized, placebo-controlled trial of the BTK inhibitor zanubrutinib in hospitalized patients with COVID-19 respiratory distress: immune biomarker and clinical findings by Steven P. Treon, Camille N. Kotton, David J. Park, Giorgia Moranzoni, Camilla K. Lemvigh, Joseph C. Gathe, Tilly A. Varughese, Christopher F. Barnett, Johnny M. Belenchia, Nina M. Clark, Charles M. Farber, Muhammad Bilal Abid, Gulrayz Ahmed, Christopher J. Patterson, Maria L. Guerrera, Jacob D. Soumerai, Vipheaviny A. Chea, Isabel P. Carulli, Jackson Southard, Shuqiang Li, Catherine J. Wu, Kenneth J. Livak, Eric Holmgren, Pil Kim, Carrie Shi, Holly Lin, Vanitha Ramakrishnan, Ying Ou, Scott Olszewski, Lars Rønn Olsen, Derin B. Keskin, Derin B. Keskin, Zachary R. Hunter, Christopher Tankersley, Todd Zimmerman, Binod Dhakal

“…Lower levels of granulocyte colony-stimulating factor, interleukin (IL)-10, monocyte chemoattractant protein-1, IL-4, and IL-13 were observed in zanubrutinib-treated patients. …”
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Impaired inflammatory resolution with severe SARS-CoV-2 infection in leptin knock out obese hamster by Ren-Di Jiang, Yun-Zhe Luo, Hao-Feng Lin, Xiao-Shuang Zheng, Wen-Tao Zeng, Mei-Qin Liu, Hao-Hao Deng, Qi Wang, Ya-Na Lai, Ying Chen, Zi-Shuo Guo, Ya Zeng, Qian-Chun Gong, Chen Qiu, Mei Dong, Xi Wang, Zi-Yi Wang, Li-Na Ji, Pan-Pan Hou, Qian Li, Xu-Rui Shen, Bei Li, Yun Gao, Ai-Hua Zhang, Ting-Ting Jiang, Ai-Min Shi, Peng Zhou, Xin-Hua Lin, Zi-Qing Deng, Jian-Min Li, Zheng-Li Shi

“…Using single-cell transcriptomics on lung tissues pre- and post-infection, we found that monocyte-derived alveolar macrophages (MD-AM) play a key role in lung hyper-inflammation, including two unique MD-AM cell fate branches specific to Leptin−/− hamsters. …”
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Adenosine Inhibits the Release of Arachidonic Acid in Activated Human Peripheral Mononuclear Cells. A Proposed Model for Physiologic and Pathologic Regulation in Systemic Lupus Ery... by Sándor Sipka

“…The AA production of monocytes mainly depends on two (IV and VI) types of PLA2 enzymes. …”
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The Expression and Clinical Significance of Different Forms of Mer Receptor Tyrosine Kinase in Systemic Lupus Erythematosus by Huaqun Zhu, Xiaolin Sun, Lei Zhu, Fanlei Hu, Lianjie Shi, Zhanguo Li, Yin Su

“…The expression of mMer on the surfaces of CD14+ monocytes/macrophages was evaluated by flow cytometry (FCM). …”
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The Macrophage Inflammatory Proteins MIP1α (CCL3) and MIP2α (CXCL2) in Implant-Associated Osteomyelitis: Linking Inflammation to Bone Degradation by Ulrike Dapunt, Susanne Maurer, Thomas Giese, Matthias Martin Gaida, Gertrud Maria Hänsch

“…MIPs were expressed predominantly at osteolytic sites, in close correlation with CD14 which was used as marker for monocytes/macrophages. Colocalisation of MIPs with monocytic cells could be confirmed by histology. …”
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Increased TNF-α Initiates Cytoplasmic Vacuolization in Whole Blood Coculture with Dengue Virus by Rahmat Dani Satria, Tzu-Wen Huang, Ming-Kai Jhan, Ting-Jing Shen, Po-Chun Tseng, Yun-Ting Wang, Zhen-Yu Yang, Chung-Hsi Hsing, Chiou-Feng Lin

“…Notably, DENV exposure caused significant vacuolization in monocytic phagocytes. With a minor change in the complete blood cell count, except for a minor increase in neutrophils and a significant decrease in monocytes, the immune profiling assay identified several changes, particularly a significant reduction in CD14-positive monocytes as well as CD11c-positive dendritic cells. …”
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The Numerical Predominance and Large Transcriptome Differences of Neutrophils in Peripheral Blood Together Inevitably Account for a Reported Pulmonary Tuberculosis Signature by Kang Wu, Ka-Wing Wong, Wang-Long Deng, Hao Zhang, Jing Li, Douglas B. Lowrie, Xiao-Yong Fan

“…By extending the analysis to the entire 393 transcripts of PTBsig and by switching the cell proportions between separated monocytes, CD4+ T cells, CD8+ T cells, and neutrophils, we create putative PTBsig for whole blood (pPTBsig) in which CD4+ or CD8+ T cells or monocytes predominated or in which the cell proportions were unchanged. …”
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3-(5-Hydroxyphenyl)-5-Phenyl-2-Pyrazolines as Toll-Like Receptor 7 Agonists by Ji Hwan Kim, Seunghyun Ahn, Dongsoo Koh, Young Han Lee, Yoongho Lim, Soon Young Shin

“…Treatment with compound 6 rapidly induced phosphorylation of IRAK4, IKKα/β, IκBα, and p65/RelA in THP1 monocytic cells. In addition, it increased the expression of NF-κB-regulated innate cytokines, such as TNFα and IL1β, in THP1 monocytic cells. …”
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Changes in Eicosanoid and Tumour Necrosis Factor-α Production by Rat Peritoneal Macrophages During Carrageenin-Induced Peritonitis by W. M. Pruimboom, A. Verdoold, C. J. A. M. Tak, A. P. M. van Dijk, M. van Batenburg, J. H. P. Wilson, F. J. Zijlstra

“…The production capacity of the peripheral blood monocytes was not similar to that of the peritoneal Mϕ.…”
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Exploiting gasdermin-mediated pyroptosis for enhanced antimicrobial activity of phage endolysin against Pseudomonas aeruginosa by Dorota Kuc-Ciepluch, Karol Ciepluch, Daria Augustyniak, Grzegorz Guła, Barbara Maciejewska, Artur Kowalik, Ewelina Jop, Zuzanna Drulis-Kawa, Michał Arabski

“…LPS-induced pyroptosis in monocytes led to GSDMD cleavage and the release of interleukins, regardless of the nature/origin of the LPS used. …”
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Cancer-specific innate and adaptive immune rewiring drives resistance to PD-1 blockade in classic Hodgkin lymphoma by Julia Paczkowska, Ming Tang, Kyle T. Wright, Li Song, Kelsey Luu, Vignesh Shanmugam, Emma L. Welsh, Jason L. Weirather, Naomi Besson, Harrison Olszewski, Billie A. Porter, Kathleen L. Pfaff, Robert A. Redd, Fathima Zumla Cader, Elisa Mandato, Jing Ouyang, Eleonora Calabretta, Gali Bai, Lee N. Lawton, Philippe Armand, Scott J. Rodig, Xiaole Shirley Liu, Margaret A. Shipp

“…Importantly, a population of circulating and tumor-infiltrating IL1β+ monocytes/macrophages is detectable in patients with cHL but not healthy donors, and a proinflammatory, tumor-promoting signature of these circulating IL1β+ monocytes is associated with resistance to PD-1 blockade in cHL. …”
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Deviations in Circulating TNFα Levels and TNFα Production by Mononuclear Cells in Healthy Human Populations by T. Mózes, I. Baráth, K. Gornicsar, A. Grosz, Ta. Mózes, Cs. Göndöcs, P. Széphalmi, K. Gaál, E. Madarász

“…The serum-level of TNFα and the production of TNFα by lympho/monocytes, however, seem to show high individual variations. …”
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Efek Suplementasi Selenium terhadap Marker Darah Pasca Cedera Kontusio by Mariel Daba, Hanna Goenawan, Vita Murniati Tarawan, Aziis Mardanarian Rosdianto, Ronny Lesmana

“…Examination of markers such as White Blood cells (WBC), lymphocytes, monocytes, and neutrophils was carried out on day three after treatment. …”
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The determination of alpha naphthyl acetate esterase (anae) positivity in peripheral blood leukocytes of kyrgyzstan?s mountain yaks (bos grinniens) by Nariste Kadıralieva, Emrah Sur, Yasemin Öznurlu, Tuğba Özaydın

“…<b>Aim:</b> A lysosomal enzyme, alpha naphthyl acetate esterase (ANAE), has been used to differentiate T and B lymphocytes, and monocytes in various species in peripheral blood smears. …”
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Receptors That Inhibit Macrophage Activation: Mechanisms and Signals of Regulation and Tolerance by Ranferi Ocaña-Guzman, Luis Vázquez-Bolaños, Isabel Sada-Ovalle

“…We chose the receptors TIM-3, PD-1, CD32b, and CD200R because these molecules have distinct functional characteristics that provide examples of the different regulating mechanisms in monocytes and macrophages.…”
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Mixed Phenotype Acute Leukemia Presenting as Leukemia Cutis by Geetha Narayanan, M. T. Sugeeth, Lali V. Soman

“…Skin biopsy showed leukemic infiltration and bone marrow aspiration showed MPAL of the T/myeloid with monocytic differentiation lineage. This is the first report of an adult patient with MPAL of the T/myeloid with monocytic differentiation type presenting with leukemia cutis. …”
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Haematological Features of White Rats (Rattus norvegicus) Infected with S. pyogenes and Administered with Probiotics (Yogurt) by Novina Rahmawati, Maimun Syukri, Darmawi Darmawi, Indra Zachreini, Utari Zulfiani, Muhammad Yusuf, Rinaldi Idroes

“…Haematological analysis of the rats’ blood was performed on the following parameters: platelets, leukocytes, lymphocytes, neutrophils, and monocytes, where the data were further processed using ANOVA and Duncan’s test with a confidence level of 95% (0.05). …”
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Influence of Vanadium 4+ and 5+ Ions on the Differentiation and Activation of Human Osteoclasts by Matthias A. König, Oliver P. Gautschi, Hans-Peter Simmen, Luis Filgueira, Dieter Cadosch

“…In addition, the influence of V ions on the activation and function of in vitro generated OC was observed. Methods. Human monocytes and osteoclasts were isolated from peripheral blood monocytic cells (PBMCs). …”
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Listeria monocytogenes use multiple mechanisms to disseminate from the intestinal lamina propria to the mesenteric lymph nodes by Joshua S. Nowacki, Grant S. Jones, Sarah E. F. D'Orazio

“…We show here that CCR2−/− mice had a significant reduction in Ly6Chi monocytes in the MLN but no change in bacterial burden following foodborne infection; thus, dissemination of L. monocytogenes associated with monocytes is not required for colonization of the MLN. …”
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Hematological profile and its correlation with reverse transcription–polymerase chain reaction-based serial quantitative detection of BCR-ABL in chronic myeloid leukemia patients a... by Vanita Pandey, Tamojit Chaudhuri, Amitabh Upadhyay, Somshankar Chowdhury, Sujata Mitra

“…Mean neutrophils, lymphocytes, monocytes, basophils, and platelets were normal. The eosinophil count was raised. …”
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