Successful Desensitization of a Patient with Rituximab Hypersensitivity by Pinar Ataca, Erden Atilla, Resat Kendir, Sevim Bavbek, Muhit Ozcan

“…Rituximab is a monoclonal antibody which targets CD20 in B cells that is used for the treatment of CD20 positive oncologic and hematologic malignancies. …”
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Non-diffuse Large B-cell Lymphoma. Case Presentation by Miguel Ángel Serra Valdés, Yasniel Borrego Moreno, Marleny Viera García

“…Clinical studies, imaging, aspiration cytology, medullogram and spinal biopsy and lymph node biopsy allowed diagnosis and staging to begin treatment with cyclophosphamide, doxorubicin, vincristine and prednisone plus the monoclonal antibody rituximab according to the protocol for these tumors. …”
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Longstanding Eosinophilic Gastroenteritis of More Than 20 Years by Hugh J Freeman

“…In the future, treatment of EGE may involve monoclonal antibody agents that target the specific biological effects of the eosino-phil, apparently central to this unusual inflammatory process.…”
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Ipilimumab: A First-in-Class  T-Cell Potentiator for Metastatic Melanoma by Bartosz Chmielowski

“…Ipilimumab, a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody that potentiates antitumor T-cell responses, has demonstrated improved survival in previously treated and treatment-naïve patients with unresectable stage III/IV melanoma. …”
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Treatment of Shiga-Toxin Hus with Severe Neurologic Features with Eculizumab by Jacob H. Umscheid, Collin Nevil, Rhythm Vasudeva, Mohammed Farhan Ali, Nisha Agasthya

“…Current literature supports use of eculizumab, a monoclonal antibody that blocks complement activation, in atypical HUS (aHUS). …”
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Effects of Macrofungal Polysaccharides Combined with Vemurafenib on Melanoma and Its Associated Mechanism by Wenya Wu, Zhigang Su, Shasha Fan

“…In this study, a melanoma mouse model was constructed, and a macrofungal polysaccharide (MFPS) extracted from Pleurotus ostreatus combined with Vemurafenib monoclonal antibody was used to study their effects against melanoma and its antitumor mechanism by using the lactate dehydrogenase release assay, enzyme-linked immunosorbent assay, and flow typing assay. …”
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Trastuzumab Resistance: Role for Notch Signaling by Kinnari Mehta, Clodia Osipo

“…Trastuzumab, the humanized, monoclonal antibody directed against ErbB-2 has shown tremendous efficacy and improved overall survival for women when combined with a taxane-based chemotherapy. …”
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Anti-CD20 Treatment of Autoimmune Hemolytic Anemia Refractory to Corticosteroids and Azathioprine: A Pediatric Case Report and Mini Review by Alexandros Makis, Zoi Kanta, Dimitrios Kalogeropoulos, Nikoloaos Chaliasos

“…Another second-line option is rituximab, an anti-CD20 monoclonal antibody, which has been used as an off-label agent with encouraging results from small limited studies or case reports. …”
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Posttranslational Modifications and the Immunogenicity of Biotherapeutics by Roy Jefferis

“…The individual is naturally tolerant to molecular forms of self-molecules but nonself variants can provoke an immune response with the generation of anti-drug antibodies (ADA); aggregated forms can exhibit enhanced immunogenicity and QC procedures are developed to avoid or remove them. Monoclonal antibody therapeutics (mAbs) are a special case because their purpose is to bind the target, with the formation of immune complexes (ICs), a particular form of aggregate. …”
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Long Term Safety of Infliximab by Thomas F Schaible

“…Infliximab is a chimeric anti-tumour necrosis factor-alpha monoclonal antibody that has been studied for the treatment of Crohn’s disease and rheumatoid arthritis. …”
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Denosumab as the Treatment of Recalcitrant Tuberculous Pleural Effusion-Associated Hypercalcemia by Afdhal Afiq Abd Jalil, Sharifah Faradila Wan Muhamad Hatta, Aimi Fadilah Mohamad, Mohammed Fauzi Abdul Rani

“…Denosumab is a human monoclonal antibody that binds to RANKL (receptor activator of nuclear factor-kappa B ligand). …”
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Outside-in engineering of cadherin endocytosis using a conformation strengthening antibody by Bin Xie, Shipeng Xu, Sanjeevi Sivasankar

“…We show that the anti-cancer drug delivery monoclonal antibody CQY684, traps P-cadherin in an X-dimer conformation and strengthens this adhesive structure. …”
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Pembrolizumab-Induced Mobitz Type 2 Second-Degree Atrioventricular Block by Alisha Khan, Sana Riaz, Robert Carhart

“…Pembrolizumab is a monoclonal antibody directed towards programmed cell death protein 1 (PD-1) and is an antineoplastic drug which has a growing variety of oncologic uses. …”
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Small cell lymphocytic lymphoma of eye annexes. Case presentation by Icilany Villares Álvarez, Julio Dámaso Fernández Águila, María de los A. García Dueñas, Alejandro Pérez Capote

“…The patient was considered a stage IIIAE of Ann Arbor and treated with six cycles of cyclophosphamide, vincristine, doxorubicin and prednisone, plus the Cuban monoclonal antibody anti-CD20 CIMABior®. The complete response was reached, state in which the disease remains so far.…”
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Atezolizumab neutralizing assay development: a novel way of evaluating assay cutpoint after sample pretreatment by Rachel Melendez, Jane Ruppel, Cecilia Leddy, Jenny Yang, Ann Brady, Yenny Webb-Vargas, Jochen Brumm, Lynn Kamen, Yuan Song

“…Abstract Atezolizumab, a biotherapeutic monoclonal antibody directed against PD-L1, has been shown to be efficacious in multiple oncology indications. …”
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Recalcitrant Dermatomyositis Treated With Anifrolumab by Shivang Chaudhary, Meghan Baumer, Laura Upton, Samantha Ong, Kristin Smith, Daniel West, Adam Kilian

“…We present a case of a 38‐year‐old man with recalcitrant dermatomyositis who was successfully treated with the interferon α receptor 1‐inhibiting monoclonal antibody anifrolumab. Many studies have shown a correlation between dermatomyositis disease activity and the type 1 interferon pathway activity. …”
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Successful treatment of severe acrodermatitis continua of hallopeau with Bimekizumab: A case report by Lily Xu, Kaiyang Li, Eric Mutter, Annie Langley

“…Treatment with Bimekizumab, a monoclonal antibody that inhibits interleukin-17, led to 50% improvement by 2 months, and complete normal regrowth of all fingernails by 1 year. …”
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CC-Chemokine CCL15 Expression and Possible Implications for the Pathogenesis of IgE-Related Severe Asthma by Yasuo Shimizu, Kunio Dobashi

“…Omalizumab is a monoclonal antibody directed against immunoglobulin E, and its blocking of IgE signaling not only reduces inflammatory cell infiltration mediated by the Th2 immune response but also inhibits other immune responses. …”
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New Possibilities for the Treatment of Crohn’s Disease by Z. A. Mamieva, E. A. Poluektova, O. S. Shifrin

“…Ustekinumab is a fully human monoclonal antibody of the IgG1k class to the p40 subunit of IL-12 and IL-23. …”
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Isatuximab for Delayed Red Cell Engraftment after Allogeneic Hematopoietic Cell Transplantation by Mary Nauffal, Stephen Eng, Andrew Lin, Alexander Chan, Kathryn Mazzerella, Sergio Giralt, Miguel-Angel Perales, Boglarka Gyurkocza

“…Isatuximab is an IgG1κ-derived monoclonal antibody against CD38 approved for the treatment of adult patients with multiple myeloma. …”
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