Reconciling predicted and measured viscosity parameters in high concentration therapeutic antibody solutions by Georgina Bethany Armstrong, Aisling Roche, William Lewis, Zahra Rattray

“…Monoclonal antibody (mAb) solution viscosity in ultra-high concentration formulations is a key developability consideration in mAb development risk mitigation strategies that has implications for downstream processing and patient safety. …”
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Clinical Implications for the Timely Diagnosis of Mycobacterium marinum in the Age of Biologic Therapy: A Case Report and Review of the Literature by Chris J. Lata, Kelle Edgar, Stephen Vaughan

“…Initiation of chronic immunosuppressant therapy including biologic monoclonal antibodies resulted in the exacerbation of initially localized disease to broadly disseminated lymphatic, joint, and myotendinous granulomatous disease and led to delay in the correct diagnosis. …”
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Affordable mRNA Novel Proteins, Recombinant Protein Conversions, and Biosimilars—Advice to Developers and Regulatory Agencies by Sarfaraz K. Niazi

“…We anticipate that mRNA technology will make protein drugs, such as natural and engineered proteins, monoclonal antibodies, and vaccines, accessible to billions of patients worldwide.…”
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CHIMERIC ANTIGEN RECEPTOR T CELLS FOR THE TREATMENT OF MULTIPLE MYELOMA by Ugo Testa, Elvira Pelosi, Germana Castelli

“…Various immunotherapy strategies have emerged as an efficacious approach for the treatment of MM, including monoclonal antibodies, antibody-drug conjugates, bispecific antibodies, and chimeric antigen receptor T (CAR-T) cells. …”
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Occupationally Acquired American Cutaneous Leishmaniasis by Maria Edileuza Felinto de Brito, Maria Sandra Andrade, Éricka Lima de Almeida, Ângela Cristina Rapela Medeiros, Roberto Pereira Werkhäuser, Ana Isabele Freitas de Araújo, Sinval Pinto Brandão-Filho, Alzira Maria Paiva de Almeida, Eduardo Henrique Gomes Rodrigues

“…One isolate was obtained by culture (from patient 2 biopsy samples) and characterized as Leishmania (Viannia) naiffi through an indirect immunofluorescence assay (IFA) with species-specific monoclonal antibodies (mAbs) and by multilocus enzyme electrophoresis (MLEE). …”
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New Concepts in the Diagnosis and Pathogenesis of Trichomonas vaginalis by Renuka Bhatt, Mary Abraham, Dino Petrin, Gary E Garber

“…The application of monoclonal antibodies, either singly or in a group that recognizes a common antigen, along with methods such as detection of common DNA fragment from clinical specimens, may have a promising future in the laboratory diagnosis of trichomoniasis.…”
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Cost and supply considerations for antibody therapeutics by Chun Chen, Zoe Garcia, David Chen, Hong Liu, Piper Trelstad

“…Monoclonal antibodies (mAbs) and mAb-derived biologics have achieved substantial success across various therapeutic areas over recent decades. …”
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Isolation and function of a human endothelial cell C1q receptor by M. R. Daha, L. Dunn, R. van den Berg, Y. Muizert-de Lange, A. Gerritsen, L. A. van Es

“…Both monoclonal antibodies increased the binding of 125I-C1q to endothelial cells but F(ab')2 anti-C1qR mAb inhibited the binding of a125I-C1q to EC in a dosedependent manner. …”
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Identification of Specific Cell Surface Markers on Immune Cells of Squirrel Monkeys (Saimiri sciureus) by Bharti P. Nehete, Ashley DeLise, Pramod N. Nehete

“…We established cross-reactivity of commercial mouse antihuman monoclonal antibodies (mAbs), with these various immune cell surface markers. …”
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Inhibitory effect of interferon-beta on mouse spleen-derived mast cells by S. Konno, M. Adachi, K. Asano, K. Okamoto, T. Takahashi

“…The suppressive effect of Mu-rIFNs on IC-2 cells was selectively abolished by monoclonal antibodies against Mu-rIFN-β and −γ.…”
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Review of the clinical status of cardiotoxicity of HER-2 positive breast cancer targeted therapeutic drugs by Xiang Zhang, Yulian Yin, Qiuting Yu, Xinlin Chen, Yiqin Cheng

“…In this paper, we classify them into three categories: monoclonal antibodies (mAbs), small-molecule tyrosine kinase inhibitors (TKIs), and antibody-drug conjugate (ADCs). …”
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Soy 11S Globulin Acid Subunits as the Novel Food Polymer Carrier by Lei Chen, Dahai Liu, Guohua Wu, Yuanyuan Ma

“…Aflatoxins were conjugated with soy 11S globulins acid subunits and the hapten-specific monoclonal antibodies (McAbs) cross-reactive with four major aflatoxins were achieved using indirect competitive ELISA screening procedure. …”
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Analysis of KRAS Mutations of Exon 2 Codons 12 and 13 by SNaPshot Analysis in Comparison to Common DNA Sequencing by Rica Zinsky, Servet Bölükbas, Holger Bartsch, Joachim Schirren, Annette Fisseler-Eckhoff

“…Due to the call for fast KRAS mutation status analysis for treatment of patients with monoclonal antibodies for metastatic colorectal cancer, sensitive, economic, and easily feasible methods are required. …”
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The Association Between Human Cytomegalovirus and Salivary Gland Cancer: An Analytical Study and Literature Review by Hagir Abd Rahman Mahmoud, Ahmed Mohamed Suleiman, Elwaleed Mohamed Elamin, Sawsan Abdel Rahim Mohammed

“…Immunohistochemical staining for CMV was performed using monoclonal antibodies to detect the presence of the virus among the studied group. …”
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A pivotal decade for bispecific antibodies? by Marlena Surowka, Christian Klein

“…Bispecific antibodies (bsAbs) are a class of antibodies that can mediate novel mechanisms of action compared to monospecific monoclonal antibodies (mAbs). Since the discovery of mAbs and their adoption as therapeutic agents in the 1980s and 1990s, the development of bsAbs has held substantial appeal. …”
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Plasmapheresis for Pembrolizumab-Induced Hepatitis in a Patient with Squamous Cell Carcinoma and Prior Orthotopic Liver Transplantation by Sanaa Al-Nattah, Kusum Lata Sharma, Matthew Caldis, Erin Spengler, William N. Rose

“…Checkpoint inhibitor therapy with monoclonal antibodies against programmed cell death protein 1 (PD1) has been implemented in the treatment of numerous malignancies. …”
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New Antibody Conjugates in Cancer Therapy by Serengulam V. Govindan, David M. Goldenberg

“…Targeting of radiation, drugs, and protein toxins to cancers selectively with monoclonal antibodies (MAbs) has been a topic of considerable interest and an area of continued development. …”
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Serum Interleukin-6 Expression Level and Its Clinical Significance in Patients with Dermatomyositis by Min Yang, Xiaomin Cen, Qibing Xie, Chuan Zuo, Guixiu Shi, Geng Yin

“…IL-6 plays a less important role in DM than in RA. IL-6 monoclonal antibodies may have poor effect in patients with DM.…”
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A novel label-free method to determine equilibrium dissociation constants of antibodies binding to cell surface proteins by Eilyn R. Lacy, Rupesh Nanjunda, Scott L. Klakamp, Deborah Kwok, Jennifer F. Nemeth, Gordon D. Powers, H. Hugo Caicedo, Steven A. Jacobs

“…MSD-CAT was used to evaluate the binding of monoclonal antibodies, Fab fragments, and bispecific antibodies targeting the cell-surface receptor interleukin 3 receptor alpha (CD123) and the results were compared to data obtained using surface plasmon resonance (SPR). …”
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Development and Characterization of Anti-Nitr9 Antibodies by Radhika N. Shah, Ivan Rodriguez-Nunez, Donna D. Eason, Robert N. Haire, Julien Y. Bertrand, Valērie Wittamer, David Traver, Shila K. Nordone, Gary W. Litman, Jeffrey A. Yoder

“…In an effort to better understand the role of NITRs in zebrafish immunity, anti-Nitr9 monoclonal antibodies were generated and evaluated for the ability to recognize the three Nitr9 isoforms. …”
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