The real-world safety of Ofatumumab: a pharmacovigilance analysis based on the FDA adverse event reporting system by Yue Zhou, Yutong Wu, Xiao Zhao, Lingxu Xu, Mingguang Sun, Zhaoyou Meng

“…BackgroundOfatumumab is a humanized monoclonal antibody that targets CD20-positive B cells. …”
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Azithromycin Inhibits Mucus Hypersecretion from Airway Epithelial Cells by Takeshi Shimizu, Shino Shimizu

“…Mucus secretion was evaluated by enzyme-linked immunosorbent assay using an anti-MUC5AC monoclonal antibody. AZM or CAM significantly inhibited tumor necrosis factor-α (TNF-α) (20 ng/mL)-induced MUC5AC secretion from NCI-H292 cells at 10−6–10−7 M, whereas JM or ABPC showed no effect. …”
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Identification of Type VI Collagen Synthesizing Cells in Human Diabetic Glomerulosclerosis Using Renal Biopsy Sections by Mohammed Shawkat Razzaque, Takehiko Koji, Takashi Harada, Takashi Taguchi

“…Type VI collagen‐specific oligonucleotide probes and monoclonal antibody were used to assess the relative expression of mRNA for \alpha1 (VI) chain and its translated protein in paraffin‐embedded renal biopsy sections of DN. …”
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Bioinformatic Analysis of PTTG Family and Prognosis and Immune Cell Infiltration in Gastric Cancer by Xiao Li, Yanghao Tai, Shuying Liu, Yating Gao, Kaining Zhang, Jierong Yin, Huijuan Zhang, Xia Wang, Xiaofei Li, Dongfeng Zhang

“…Adaptive cell therapy, cancer vaccines, gene therapy, and monoclonal antibody therapy have all been used in gastric cancer with some initial success. …”
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Chemotherapy in the Setting of Severe Liver Dysfunction in Patients with Metastatic Colorectal Cancer by Pashtoon Murtaza Kasi, Gita Thanarajasingam, Heidi D. Finnes, Jose C. Villasboas Bisneto, Joleen M. Hubbard, Axel Grothey

“…If we were to focus on just the metabolism of the different drugs and biologic agents available to treat mCRC, both 5-fluorouracil and oxaliplatin alone or in combination with a monoclonal antibody are reasonable choices. Specifically, FOLFOX is a feasible and safe option in patients with mCRC with severe liver dysfunction. …”
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Lyophilised protein formulations as a patient-centric dosage form: A contribution toward sustainability paradigm by Žiberna Maja Bjelošević, Grabnar Pegi Ahlin, Gašperlin Mirjana, Matjaž Mirjam Gosenca

“…To gain further knowledge and fill the gaps in the already constructed data platform for the development of monoclonal antibody formulations, we designed a study that examines small model proteins, i.e., bovine serum albumin. …”
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Approach to Management of Thrombotic Thrombocytopenic Purpura at University of Cincinnati by N. Abdel Karim, S. Haider, C. Siegrist, N. Ahmad, A. Zarzour, J. Ying, Z. Yasin, R. Sacher

“…Plasma exchange (PE) is the main stay of treatment in combination with steroids and immunosuppressive therapies. The monoclonal antibody against CD20 Rituximab decreases the production of antibodies from B lymphocytes and it is used for antibodies-mediated diseases including TTP. …”
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Bevacizumab Demonstrates Prolonged Disease Stabilization in Patients with Heavily Pretreated Metastatic Renal Cell Carcinoma: A Case Series and Review of the Literature by Nicole M. Agostino, Rebecca Gingrich, Joseph J. Drabick

“…Bevacizumab, a monoclonal antibody directed against the ligand, VEGF, has shown activity against RCC as a single agent in patients who had failed prior cytokine therapy and as first line therapy in combination with interferon. …”
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BlockingαVβ3 Integrin Ligand Occupancy Inhibits the Progression of Albuminuria in Diabetic Rats by Laura A. Maile, Katherine Gollahon, Christine Wai, Paul Dunbar, Walker Busby, David Clemmons

“…Diabetic rats were treated with either vehicle or a monoclonal antibody that binds the β3 subunit of the αVβ3 integrin. …”
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Effectiveness of Palivizumab in Preventing RSV Hospitalization in High Risk Children: A Real-World Perspective by Nusrat Homaira, William Rawlinson, Thomas L. Snelling, Adam Jaffe

“…Palivizumab, a humanized monoclonal antibody, has been recommended for high risk infants to prevent severe RSV-associated respiratory illness. …”
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In Vivo 3T Magnetic Resonance Imaging Using a Biologically Specific Contrast Agent for Prostate Cancer: A Nude Mouse Model by Christopher Brian Abraham, Prashant Jani, Roxanne Turuba, Michael Campbell, Ingeborg Zehbe, Laura Curiel

“…The agent was developed by conjugating Molday ION™ carboxyl-6 (MIC6), with a deimmunized mouse monoclonal antibody (muJ591) targeting prostate-specific membrane antigen (PSMA). …”
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Efficacy and safety of ustekinumab in the treatment of moderate to severe plaque psoriasis in Singapore by Wai Sze Agnes Chan, Yisheng Wong, Hazel Hwee Boon Oon, Colin Thiam Seng Theng, Wei-Sheng Chong

“…Introduction: Ustekinumab is a human monoclonal antibody that binds to the p40 subunit of both interleukin (IL)-12 and IL-23, and it is approved for the treatment of moderate to severe plaque psoriasis. …”
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Cytokine profiles in early rejection following OKT3 treatment in liver transplant patients by Sasan Roayaie, Patricia A. Sheiner, Sukru Emre, Steven Guy, Myron E. Schwartz, Peter Boros, Charles M. Miller

“…OKT3, a murine monoclonal antibody specific to the human CD3 complex, induces immunosuppression by depletion of T cells. …”
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The Role of PAM4 in the Management of Pancreatic Cancer: Diagnosis, Radioimmunodetection, and Radioimmunotherapy by Suxia Han, Guihua Jin, Lijuan Wang, Meng Li, Chenchen He, Xijing Guo, Qing Zhu

“…PAM4, a new monoclonal antibody (MAb) known as clivatuzumab, is highly reactive with pancreatic cancer and precursor lesions. …”
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A Rare Case of Immunotactoid Glomerulopathy Associated with Hodgkin Lymphoma by Keiki Nagaharu, Yuka Sugimoto, Keiki Kawakami

“…The existence of a monoclonal antibody itself might not be a sufficient factor for ITG in some cases, and an additive trigger is necessary for development.…”
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An Association between Bevacizumab and Recurrent Posterior Reversible Encephalopathy Syndrome in a Patient Presenting with Deep Vein Thrombosis: A Case Report and Review of the Lit... by Mark Lazarus, Stanley Amundson, Rajesh Belani

“…Causes of PRES include preeclampsia/eclampsia, hypertension, and recently bevacizumab, a monoclonal antibody vascular endothelial growth factor (VEGF) inhibitor. …”
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The dawn of preventing respiratory syncytial virus lower respiratory tract infections in children by Z Dangor, S A Madhi, H Zar, D Demopoulos

“…Recently, two new RSV prevention strategies have emerged: nirsevimab, a long-acting monoclonal antibody, and a maternal RSV vaccine. Both strategies have shown high efficacy in reducing RSV-LRTI hospitalisation in infants and are being considered for licensure in SA. …”
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Invasive Aspergillosis in a Patient with Stage III (or 3a or 3b) Non-Small-Cell Lung Cancer Treated with Durvalumab by Ashish Gupta, Aung Tun, Katy Ticona, Aam Baqui, Elizabeth Guevara

“…Durvalumab is a therapeutic monoclonal antibody that blocks the checkpoint inhibitor, programmed death ligand 1 (PD-L1), resulting in T-cell activation and an antitumor response. …”
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Tuberculosis of the tongue in a patient under treatment with adalimumab by Cintia Mussi Milani, Rafaela Arana, Rafaela Sávio Melzer, Antônio Adilson Soares Lima, Maria Angela Naval Machado, Liliane Roskamp

“…Among the predisposing factors to the disease, adalimumab, a monoclonal antibody used as an effective therapy in patients with rheumatic disorders, including psoriatic arthritis, increases the risk of active tuberculosis development. …”
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Neutrophilic Cell-Free Exudate Induces Antinociception Mediate by the Protein S100A9 by Rosana L. Pagano, Mario Mariano, Renata Giorgi

“…The transference of exudates also induced antinociceptive effect, and neutralization of S100A9 activity by anti-S100A9 monoclonal antibody totally reverted this response. This effect was not observed when experiments were made 24 or 48 hours after glycogen injection. …”
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