Characteristics and multi-omics analysis of spontaneous spondyloarthritis in non-human primates: Case report by Lei Cai, Qing Lv, Ronghua Ma, Wei Liu, Yalun Guan, Zhongqiang Huang, Qingyu Liu, Yunfeng Li, Shuhua Liu, Ge Li, Yu Zhang

“…MRI imaging further confirmed inflammatory changes in the spine and facet joints of these monkeys, along with inflammation and bone destruction in peripheral joints. …”
Get full text

Characterization of LY3324954 a long-acting glucagon-receptor agonist by William Roell, Tamer Coskun, Teayoun Kim, Libbey O’Farrell, Jennifer A. Martin, Shelly Nason, Jasmin Hernandez-Alamillo, Saidharshana Dhantu, Daniel J. Drucker, Kyle W. Sloop, James P. Steele, Jorge Alsina-Fernandez, Kirk M. Habegger

“…Methods: LY3324954 was administered to DIO mice, rats, dogs, and monkeys to evaluate pharmacokinetic (PK) profile. …”
Get full text

Nonclinical Similarity of the Biosimilar Candidate ABP 938 with Aflibercept Reference Product by Neungseon Seo, Scott Kuhns, Dina A. Andrews, Alexander Colbert, Vincent Chow, Jennifer Liu

“…Safety was assessed in a 1-month IVT study in cynomolgus monkeys. Results SPR results demonstrated that ABP 938 is similar to aflibercept RP in binding kinetics and affinity for VEGF-A111, VEGF-A121, VEGF-A165, VEGF-A189, PlGF-1, and PlGF-2 isoforms. …”
Get full text

奇异的松鼠猴 by 华惠伦

“…名貌不符根据松鼠猴分布地区的不同和毛色的差异,动物分类学家把它分为普通松鼠猴,巴拿马松鼠猴、巴西松鼠猴和太平洋松鼠猴四种,种下又分为十五个亚种。松鼠猴一名,从英文 Sguirrl Monkeys 翻译而…”
Get full text

The evolution of primate vocal communication: a social route by Alban Lemasson, Camille Coye, Nancy Rebout, Florence Levréro

“…We first addressed this topic in two sympatric guenons, Diana monkeys and Campbell’s monkeys. Interspecies competition, and the niche specialisations this creates, appeared to be a key evolutionary driver of their repertoires. …”
Get full text

Effects of Immediate or Delayed Estradiol on Behavior in Old Menopausal Macaques on Obesogenic Diet by Kristine Coleman, Nicola D. Robertson, Adriane Maier, Cynthia L. Bethea

“…The DE-treated monkeys were not different from placebo-controls in these 2 outcomes. …”
Get full text

Chloroquine and Rapamycin Augment Interleukin-37 Expression via the LC3, ERK, and AP-1 Axis in the Presence of Lipopolysaccharides by Xiaoyi Shi, Chunhui Lai, Lianyu Zhao, Mingying Zhang, Xi Liu, Shanqin Peng, Weizhong Guo, Qiuying Xu, Song Chen, Guang-xing Chen

“…Healthy human peripheral blood mononuclear cells were treated similarly to confirm our results. Four rhesus monkeys were also administered chloroquine to evaluate IL-37 induction in vivo and its bioactivity on CD4 proliferation and activation. …”
Get full text

FORCE platform overcomes barriers of oligonucleotide delivery to muscle and corrects myotonic dystrophy features in preclinical models by Timothy Weeden, Tyler Picariello, Brendan Quinn, Sean Spring, Pei-Yi Shen, Qifeng Qiu, Benjamin F. Vieira, Lydia Schlaefke, Ryan J. Russo, Ya-An Chang, Jin Cui, Monica Yao, Aiyun Wen, Nelson Hsia, Tama Evron, Katy Ovington, Pei-Ni Tsai, Nicholas Yoder, Bo Lan, Reshmii Venkatesan, John Hall, Cody A. Desjardins, Mo Qatanani, Scott Hilderbrand, John Najim, Zhenzhi Tang, Matthew K. Tanner, Romesh Subramanian, Charles A. Thornton, Oxana Ibraghimov-Beskrovnaya, Stefano Zanotti

“…Low monthly dosing of DYNE-101 in TfR1 hu/mu ;DMSXL WT/Tg mice or cynomolgus monkeys leads to a profound reduction of DMPK expression in muscle. …”
Get full text

Bright night sleeping environment induces diabetes and impaired glucose tolerance in non-human primates by Shuxing Wang, Zhenyi Chen, Zihao Liang, Qiang Xu, Jiankai Zhang

“…This study aims to address these questions in monkeys.MethodsIn a reduced daytime bright condition resembling human living rooms, 197 Cynomolgus (130 male, 67 female) were exposed to three distinct light intensities (13, 35, 75Lux) at night for consecutive ten months. …”
Get full text

Le complexe des trois singes. Sur un certain journalisme primatologique by Etienne Bimbenet

“…The latter attitude is what I call the “three monkeys’ complex.”This project will analyse a series of “scoops” supposed to teach us that “language,” “self-consciousness,” or “tools” are no longer exclusively human. …”
Get full text

Spontaneous, naturally occurring cancers in non-human primates as a translational model for cancer immunotherapy by Maurizio Ceppi, Bruno Gomes, Simon Deycmar, Jehad Charo, J Mark Cline

“…Thus, these tumor-bearing monkeys (TBMs) have the potential to bridge the experimental gap between early preclinical cancer models and patients with human cancer.This review presents our current knowledge of NHP immunology, the incidence and features of naturally-occurring cancers in NHP, and recent TBM trials investigating CIT to provide a scientific rationale for this unique model for human cancer.…”
Get full text

Distinct role of primate DLPFC and LIP in hierarchical control of learned saccade sequences by Qingjun Wang, Binchao Shi, Jing Jia, Jingyu Hu, Haoran Li, Xin Jin, Aihua Chen

“…Summary: Learned action sequences are suggested to be organized hierarchically, but how the various hierarchical levels are processed by different cortical regions remains largely unknown. By training monkeys to perform heterogeneous saccade sequences, we investigated the role of the dorsolateral prefrontal cortex (DLPFC) and the lateral intraparietal cortex (LIP) in sequence planning and execution. …”
Get full text

Facial Anthropometry and Self-expressed Behaviours: A Systematic Review by Ankit Srivastava, Vilas Chimurkar, Nisha Mani Pandey, Anand Bihari

“…The identified titles and abstracts were screened independently by two authors and studies that mentioned facial anthropometry in relation to self-expressed behaviour or personality in humans and monkeys were included. Results: This review describes the statistical results and conclusions of 17 studies regarding different behaviours and their relation to facial anthropometry. …”
Get full text

Babuinare by Joana Antunes

“…Based on this affinity, we will seek to identify and, whenever possible, interpret some of the most significant representations of monkeys in medieval marginalia in Portugal during the 14th century, of which two unpublished case studies stand out.…”
Get full text

Figs Are More Than Fallback Foods: The Relationship between Ficus and Cebus in a Tropical Dry Forest by Nigel A. Parr, Amanda D. Melin, Linda Marie Fedigan

“…However, for white-faced capuchin monkeys (Cebus capucinus) living in northwestern Costa Rica, figs are a consistently important resource and may increase groupwide energy intake. …”
Get full text

Prefrontal cortex contribution in transitive inference task through the interplay of beta and gamma oscillations by Fabio Di Bello, Valentina Mione, Pierpaolo Pani, Emiliano Brunamonti, Stefano Ferraina

“…To dig into the neural substrate driving TI cognitive processes, we examine the role of beta and gamma local field potential bands in the prefrontal cortex of 2 monkeys. During the inferential problem-solving period, we discover a tight link between beta and gamma bands modulation and TI complexity. …”
Get full text

Contribution à la ré-évaluation de l’aire de répartition du singe à queue de soleil (Cercopithecus solatus) by Peggy Motsch, Guillaume Le Flohic, Jeremy Leclercq, Jean-Paul Gonzalez

“…The sun-tailed monkeys (Cercopithecus solatus) is an endemic species of Gabon, where it was first observed in 1984 by Mike Harrison and described in 1988. …”
Get full text

To what extent are call combinations in chimpanzees comparable to syntax in humans? by Maël Leroux

“…However, evidence for combinatorial capacities in a wide variety of species, such as birds and monkeys, has challenged this assumption. Nevertheless, a contentious debate surrounding the evolutionary origins of syntax remains, specifically whether the combinatorial capacities displayed in animals merely illustrate a case of convergent evolution or whether it could also represent, within the primate lineage, a homologous trait to syntax in humans. …”
Get full text

Lipopolysaccharide Increases Immune Activation and Alters T Cell Homeostasis in SHIVB’WHU Chronically Infected Chinese Rhesus Macaque by Gao-Hong Zhang, Run-Dong Wu, Hong-Yi Zheng, Xiao-Liang Zhang, Ming-Xu Zhang, Ren-Rong Tian, Guang-Ming Liu, Wei Pang, Yong-Tang Zheng

“…The downregulated effector memory cells are associated with a lower frequency of monofunctional and polyfunctional cells, and an upregulated programmed cell death-1 (PD-1) expression on CD4+ and CD8+ T cells was observed in monkeys after LPS stimulation. Our data provide new insights into the function of LPS in the immune activation in SHIV/HIV infection.…”
Get full text

The multifaceted role of the inferior colliculus in sensory prediction, reward processing, and decision-making by Xinyu Du, Haoxuan Xu, Peirun Song, Yuying Zhai, Hangting Ye, Xuehui Bao, Qianyue Huang, Hisashi Tanigawa, Zhiyi Tu, Pei Chen, Xuan Zhao, Josef P Rauschecker, Xiongjie Yu

“…Through extracellular recordings in monkeys engaged in a sound duration-based deviation detection task, we observed a 'climbing effect' in neuronal firing rates, indicative of an enhanced response over sound sequences linked to sensory prediction rather than reward anticipation. …”
Get full text