Mannose-Binding Lectin Promoter Polymorphisms and Gene Variants in Pulmonary Tuberculosis Patients from Cantabria (Northern Spain) by J.-Gonzalo Ocejo-Vinyals, Lucía Lavín-Alconero, Pablo Sánchez-Velasco, M.-Ángeles Guerrero-Alonso, Fernando Ausín, M.-Carmen Fariñas, Francisco Leyva-Cobián

“…Mannose-binding lectin is a central molecule of the innate immune system. Mannose-binding lectin 2 promoter polymorphisms and structural variants have been associated with susceptibility to tuberculosis. …”
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Interleukin-17 prevents oxidative stress from damaging osteoblast formation by inhibiting autophagic degradation of metallothionein-2 by Xueyan Ling, Cuixia Wang, Qin Feng, Tao Zhang

“…Metallothionein-2 (MT-2), as an important reactive oxygen species (ROS)-scavenging molecule, prevents oxidative stress from damaging osteoblast formation. …”
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Hydrogen Sulfide Increases Nitric Oxide Production and Subsequent S-Nitrosylation in Endothelial Cells by Ping-Ho Chen, Yaw-Syan Fu, Yun-Ming Wang, Kun-Han Yang, Danny Ling Wang, Bin Huang

“…Hydrogen sulfide (H2S) and nitric oxide (NO), two endogenous gaseous molecules in endothelial cells, got increased attention with respect to their protective roles in the cardiovascular system. …”
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Scoulerine promotes cytotoxicity and attenuates stemness in ovarian cancer by targeting PI3K/AKT/mTOR axis by Wang Fang, Zhang Yang, Pang Rui, Shi Shaohong, Wang Ran

“…Scoulerine is a potential anticancer agent against ovarian cancer and can be considered as a lead molecule for this malignancy, provided further investigations are performed.…”
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Systematic Study of the Immune Components after Ischemic Stroke Using CyTOF Techniques by Yaning Li, Yan Wang, Yang Yao, Brian B. Griffiths, Liangshu Feng, Tao Tao, Feng Wang, Baohui Xu, Creed M. Stary, Heng Zhao

“…Interestingly, CD62L, a key adhesion molecule, regulates the migration of leukocytes from blood vessels into secondary lymphoid tissues and peripheral tissues. (3) A strong leukocyte network across the brain and peripheral immune organs was identified using the R program at day 1 after ischemia, suggesting that the peripheral immune cells dramatically migrated into the ischemic areas after stroke. …”
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Atorvastatin Improves Inflammatory Response in Atherosclerosis by Upregulating the Expression of GARP by Xiaoqi Zhao, Yuzhou Liu, Yucheng Zhong, Bo Liu, Kunwu Yu, Huairui Shi, Ruirui Zhu, Kai Meng, Wei Zhang, Bangwei Wu, Qiutang Zeng

“…GARP is a newly biological membrane molecule existed on activated Tregs, which is related to the release of TGF-β. …”
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Interventional real-time molecular MRI for targeting early myocardial injury in a pig model by Timo Heidt, Simon Reiss, Julien Thielmann, Christian Weber, Alexander Maier, Thomas Lottner, Heidi R. Cristina-Schmitz, Timon Bühler, Diana Chiang, Claus Jülicher, Carolin Wadle, Ingo Hilgendorf, Dennis Wolf, Gavin Tumlinson, Luis Hortells, Dirk Westermann, Michael Bock, Constantin von zur Mühlen

“…Here, we assessed ischemic cardiac lesions non-invasively directly after ischemia/reperfusion (I/R) in a porcine model by advanced MRI techniques and molecular imaging, targeting the cell adhesion molecule P-selectin functionalized with microparticles of iron oxide (MPIO). …”
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Structural and Theoretical Studies of 2-amino-3-nitropyridine by N. S. Al-Hokbany, A. A. Dahya, I. Kh. Warad, N. M. Abd El-Salam, S. T. Akriche, M. Rzaiguib, U. Karamac, R. M. Mahfouzc

“…The calculated HOMO and LUMO energies show that charge transfer occurs within the molecule.…”
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Safety and Phosphate‐Binding Capacity of Oxylanthanum Carbonate in Healthy Volunteers by Pablo E. Pergola, Melanie S. Joy, Armando Garsd, Steve J. Hasal, Atul Khare, Guru Reddy, Pramod Gupta, William F. Finn

“…Oxylanthanum carbonate is a new molecule yielding the same phosphate‐binding capacity as lanthanum carbonate, but in a much smaller drug volume and tablet size. …”
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New derivatives of sulfonylhydrazone as potential antitumor agents: Design, synthesis and cheminformatics evaluation by Sabbah Dima A., Al-Azaideh Bara’a A., Talib Wamidh H., Hajjo Rima, Sweidan Kamal, Al-Zuheiri Aya M., Sheikha Ghassan Abu, Shraim Sawsan

“…Hence, our results emphasized the importance of electron-withdrawing groups and hydrogen bond-acceptors in the rational design of small-molecule chemical ligands targeting PI3Kα. These results agreed with the induced-fit docking against PI3Kα, highlighting the role of p-substituted aromatic rings in guiding the ligand-PI3Kα complex formation, by targeting a hydrophobic pocket in the ligand-binding site and forming π-stacking interactions with a nearby tryptophan residue.…”
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Bicarbonates for the Prevention of Postoperative Renal Failure in Endovascular Aortic Aneurysm Repair: A Randomized Pilot Trial by Véronique Brulotte, François A. Leblond, Stéphane Elkouri, Éric Thérasse, Vincent Pichette, Pierre Beaulieu

“…Biomarkers of renal injury from urine (interleukin-18 (IL-18), neutrophil gelatinase-associated lipocalin (NGAL), N-acetyl-β-D-glucosaminidase (NAG), and kidney injury molecule 1 (KIM-1)) and blood (NGAL, cystatin C) were measured at baseline and 3, 24, and 48 h postoperatively. …”
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Myo-inositol increases respiratory burst, cellular proliferation, and phagocytosis of cultured leukocytes from Nile tilapia by Edgar Junio Damasceno Rodrigues, Pedro Luiz Pucci Figueiredo de Carvalho, Vitor Fernandes Silva, Delbert M. Gatlin, III, Margarida Maria Barros

“…Myo-inositol (MI) is a functional nutrient known to positively affect growth and health parameters when supplemented in appropriate concentrations. This bioactive molecule plays an essential role by modulating several signaling pathways including those related to some immunological responses. …”
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Dexmedetomidine alleviates acute kidney injury in a rat model of veno‐arterial extracorporeal membrane oxygenation by Min Yu, Shilin Wei, Xueyang Shen, Junjie Ying, Dezhi Mu, Xiangyang Wu, Yongnan Li

“…The levels of Kidney Injury Molecule-1 (KIM-1) and N-acetyl-β-D-glucosaminidase (NAG) were also significantly reduced. …”
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Syntheses and crystal structures of the cerium-based coordination polymers poly[(acetic acid)bis(μ-5-carboxythiophene-2-carboxylato)bis(μ-thiophene-2,5-dicarboxylato)dicerium(III)]... by Niklas Ruser, Christian Näther, Norbert Stock

“…Compound 2 has an asymmetric unit composed of one CeIII cation, one TDC2− dianion, one acetate anion and one water molecule in general positions. The cerium atom is eightfold coordinated by oxygen atoms. …”
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A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy by Gerhard Frey, Ana Paula G. Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J. Boyle, Jay M. Short

“…Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein that plays several roles in cancer biology. …”
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Soluble fibres modulate dough rheology and gluten structure via hydrogen bond density and Flory-Huggins water interaction parameter by Stefano Renzetti, Lisa Lambertini, Helene C.M. Mocking-Bode, Ruud G.M. van der Sman

“…Plasticizing properties depend on the effective number of hydrogen bonding sites available in the fibre molecule (NOH,s). Humectant properties are related to the water interaction parameter derived from analysis of the sorption behaviour. …”
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Effect and curative effect of Sanqitongshu capsule combined with argatroban on neurological deficits elderly patients with acute ischemic stroke by Fang Hu, Yunping Liu, Jia Li, Hui Xuan, Huijuan Wang, Xuehai Lv

“…[Objective] To explore the effects of Sanqitongshu capsule combined with argatroban on neurological deficits and peripheral blood endothelin-1 (ET-1), CD41, CD62P and soluble intercellular adhesion molecule-1 (sICAM-1) expressions in elderly patients with acute ischemic stroke. …”
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Closer look at circulating nitric oxide levels and their association with polycystic ovary syndrome: A meta-analytical exploration by Seyed Sobhan Bahreiny, Akram Ahangarpour, Elnaz Harooni, Mahdi Amraei, Mojtaba Aghaei, Reza Mohammadpour Fard

“…In addition, nitric oxide (NO) stands out as a pivotal signaling molecule, orchestrating a symphony of physiological processes. …”
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Synthetic Method and Oil Displacement Capacity of Nano-MoS2 by Liang Zhang, Fujian Zhou, Guofa Lei, Bingyu Ge, Yuan Li, Guolin Yu, Longhao Zhao, Bojun Li, Erdong Yao

“…Due to the steric hindrance effect of the CATB molecule, the size and interlayer gap of MoS2 nanosheets increased slightly after modification. …”
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Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn by Johannes Reusch, Jan Terje Andersen, Ulrich Rant, Tilman Schlothauer

“…While prior research has mainly investigated IgG-FcRn binding kinetics with a focus on single affinity values, it has been shown that each IgG molecule can engage two FcRn molecules throughout an endosomal pH gradient. …”
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