Adsorption of n-Alkanes in Faujasite Zeolites: Molecular Simulation Study and Experimental Measurements by Aurélie Wender, Alain Barreau, Catherine Lefebvre, Angela Di Lella, Anne Boutin, Philippe Ungerer, Alain H. Fuchs

“…In order to extend this force field from siliceous to cationic zeolites, it is proposed that account be taken of the polarization component of the zeolite-molecule interaction energy. A first-order polarization term is explicitly considered for this purpose, using standard molecular polarizabilities. …”
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The Improvement of Natural Thai Bentonite Modified with Cationic Surfactants on Hexavalent Chromium Adsorption from an Aqueous Solution by Nikom Srikacha, Manop Sriuttha, Lamyai Neeratanaphan, Chatree Saiyasombat, Bundit Tengjaroensakul

“…They demonstrated that the complete intercalation of surfactant molecules on bentonite structures supported Cr(VI) adsorption. …”
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Exendin-4 Protects MIN6 Cells from t-BHP-Induced Apoptosis via IRE1-JNK-Caspase-3 Signaling by Wen-Jia Chen, Lin-Xi Wang, Yan-Ping Wang, Zhou Chen, Xiao-Ying Liu, Xiao-Hong Liu, Li-Bin Liu

“…Exendin-4 also inhibited the endoplasmic reticulum transmembrane protein IRE1, the apoptosis-related signaling molecule JNK, and c-Jun activation. Conclusions. Our findings suggest that exendin-4 ultimately reduces t-BHP-induced β-cell apoptosis. …”
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Neutrophil membrane biomimetic delivery system (Ptdser‐NM‐Lipo/Fer‐1) designed for targeting atherosclerosis therapy by Wei Li, Chang Liu, Sichuan Wang, Naifeng Liu

“…Based on the interaction of adhesion molecules, such as vascular cell adhesion molecule 1, ICAM‐1, P‐selectin, E‐selectin, and chemokines released in the inflamed site, the aorta in NM‐Lipo‐treated mice displayed 1.3‐fold greater radiant efficiency than platelet membrane‐Lipo‐treated mice. …”
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Discovering broad-spectrum inhibitors for SARS-CoV-2 variants: a cheminformatics and biophysical approach targeting the main protease by Safar M. Alqahtani

“…Accordingly, three drug molecules (BBB-26580140, BDE-32007849, and LAS-51378804) are highlighted as the best binding molecules to the main protease S1 pocket. …”
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Integrative bioinformatics and machine learning approach unveils potential biomarkers linking coronary atherosclerosis and fatty acid metabolism-associated gene by Hong Li, Yongyun Xu, Aiting Wang, Chuanxin Zhao, Man Zheng, Chunyan Xiang

“…Analysis of their biological functions underscored their significant involvement in critical processes such as fatty acid metabolism, small molecule catabolism, and nucleoside bisphosphate metabolism. …”
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Vascular Contractility Relies on Integrity of Progranulin Pathway: Insights Into Mitochondrial Function by Shubhnita Singh, Ariane Bruder, Rafael M. Costa, Juliano V. Alves, Sivakama Bharathi, Eric S. Goetzman, Thiago Bruder‐Nascimento

“…The progranulin gene (GRN) encodes glycoprotein PGRN (progranulin), a ubiquitous molecule with known anti‐inflammatory property. However, the role of PGRN in cardiovascular disease remains undefined. …”
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Assessment of the Vanillin Anti-Inflammatory and Regenerative Potentials in Inflamed Primary Human Gingival Fibroblast by Erica Costantini, Bruna Sinjari, Katia Falasca, Marcella Reale, Sergio Caputi, Srinivas Jagarlapodii, Giovanna Murmura

“…Therefore, Vanillin shows a potential therapeutic interest as an inflammatory modulator molecule with novel application in periodontal regeneration and oral health.…”
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The Response of Tissue Mast Cells to TLR3 Ligand Poly(I:C) Treatment by Piotr Witczak, Ewa Brzezińska-Błaszczyk, Justyna Agier

“…Moreover, those cells can recognize invading pathogens through a range of surface molecules known as pathogen recognition receptors (PRRs), mainly Toll-like receptors (TLRs). …”
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Podocyte-related biomarkers' role in evaluating renal toxic effects of silver nanoparticles with the possible ameliorative role of resveratrol in adult male albino rats by Eman El-Sayed Khayal, Mona G. Elhadidy, Sulaiman Mohammed Alnasser, Manal Mohammad Morsy, Azza I. Farag, Samah A. El-Nagdy

“…Ag NPs group displayed a reduction in kidney weight ( absolute and relative), excess in urinary levels of kidney injury molecule, neutrophil gelatinase-associated lipocalin, cystatin, and blood kidney biomarkers (creatinine, urea, and potassium), increases in oxidative stress markers with the reduction in antioxidant markers, and decreases in serum sirtuin 1(SIRT1) level. …”
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Thymic Stromal Lymphopoietin Is Implicated in the Pathogenesis of Bullous Pemphigoid by Dendritic Cells by Si-Zhe Li, Xin-Xing Jin, Xiao-Lei Ge, Ya-Gang Zuo, Hong-Zhong Jin

“…Infiltration of DCs, marked by DC-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN), and its relationship with TSLP and TSLP receptors was evaluated by immunofluorescence staining. …”
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Structural Features of Surface Layers of Bifunctional Polysiloxane Xerogels Containing 3-Aminopropyl Groups and 3-Mercaptopropyl Groups by Yuriy L. Zub, Inna V. Melnyk, Mark G. White, Bruno Alonso

“…When this ratio is about 1:1, the amino group forms a hydrogen bond with the silanol group associated with the water molecule. Re-organization of the surface layer is observed when the amount of water decreases, the amino groups forming hydrogen bonds between themselves. …”
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Ameliorative Effects of Polygonatum kingianum Polysaccharides on Lipid Metabolism Disorders and Brain Function Impairments in Obese Mice by XU Yuncong, YAN Qiaojuan, ZHU Chunhua, YANG Shaoqing, LI Houjiang, JIANG Zhengqiang

“…Furthermore, PKP reduced the expression levels of ionized calcium binding adaptor molecule 1 in the hippocampus and cerebral cortex by 16.0% and 28.6%, respectively, and inhibited structural damages of the hippocampus and cerebral cortex. …”
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Proinflammatory Responses of Heme in Alveolar Macrophages: Repercussion in Lung Hemorrhagic Episodes by Rafael L. Simões, Maria Augusta Arruda, Cláudio Canetti, Carlos H. Serezani, Iolanda M. Fierro, Christina Barja-Fidalgo

“…Taken together, the data support a dual role for heme in the inflammatory response associated with lung hemorrhage, acting as a proinflammatory molecule that can either act as both an adjuvant of the innate immunity and as an amplifier of the inflammatory response, leading tissue injury. …”
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Crotalaria madurensis flavonol glycosides’ antibacterial activity against Staphylococcus aureus by Hala Sh. Mohammed, Salwa A. Abu El Wafa, Mona H. Ibrahim, Rasha Mohammad Fathy, Noha A. Seif-Eldein

“…Molecular docking studies suggested that metabolite 1 exhibited the highest antioxidant and anti-MRSA activity, with strong binding scores like the ligand, indicating an effective interaction and high affinity between metabolite 1 and the target molecule.…”
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Development of a Bipolar Radio-frequency Power Supply for Structures of Lossless Ion Manipulations by Qing LIU, Run-ze XU, Yun-jing ZHANG, Ling-feng LI, Peng LI

“…On a lab-built instrument platform based on traveling wave-based structures for lossless ion manipulations (TW-SLIM), the influence of the RF voltage amplitude and frequency on the transport efficiency of small molecule ions was investigated using dimethyl methylphosphonate (DMMP) as an analyte. …”
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Single-Round Patterned DNA Library Microarray Aptamer Lead Identification by Jennifer A. Martin, Peter A. Mirau, Yaroslav Chushak, Jorge L. Chávez, Rajesh R. Naik, Joshua A. Hagen, Nancy Kelley-Loughnane

“…The sequence demonstrating the highest fluorescence intensity upon target addition was confirmed to bind the target molecule thrombin with specificity by surface plasmon resonance, and a novel imino proton NMR/2D NOESY combination was used to screen the structure for G-quartet formation. …”
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Therapeutic Potential of Stem Cells Strategy for Cardiovascular Diseases by Chang Youn Lee, Ran Kim, Onju Ham, Jihyun Lee, Pilseog Kim, Seokyeon Lee, Sekyung Oh, Hojin Lee, Minyoung Lee, Jongmin Kim, Woochul Chang

“…Various studies have recently reported increased therapeutic potential of transplantation of microRNA- (miRNA-) overexpressing stem cells or small-molecule-treated cells. In addition to treatment with drugs or overexpressed miRNA in stem cells, stem cell-derived extracellular vesicles also have therapeutic potential because they can deliver the stem cell-specific RNA and protein into the host cell, thereby improving cell viability. …”
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The effect of tumour necrosis factor-α (TNF-α) muteins on human neutrophils in vitro by H. Tchorzewski, K. Zeman, J. Kantorski, E. Paleolog, M. Kahan, M. Feldmann, M. Kwinkowski, P. Guga, B. Szymanska, P. Parniewski, A. Wilk, J. Jarosz

“…To verify the suggestion that the receptor binding domain includes the region close to the N-terminus of the TNF-α molecule, four TNF-α derivatives termed muteins were constructed, using a synthetic cDNA fragment substituting the N-terminal 3–7 selected hydrophilic or hydrophobic amino acids in the original TNF-α genomic DNA. …”
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Chemical reactivity of alliin and its molecular interactions with the M proteasepro of SARS-CoV-2 by López-Orozco Wendolyne, Mendoza-Huizar Humberto Luis, Álvarez-Romero Giaan Arturo, Torres-Valencia Jesús Martín, Sanchez-Zavala Maricruz

“…Last result suggests that this molecule is a potential candidate for further in vitro evaluation as a drug for the treatment of the major protease-based SARS-CoV-2 virus.…”
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