Comprehensive analysis of the multi-rings mitochondrial genome of Populus tomentosa by Kai Gao, Ting Guo, Xinmin An

“…This genome has a complex structure composed of four circular molecules ranging from 153,004 to 330,873 base pairs (bp). …”
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Influence of polyester fabric with infrared emissive additives on cell metabolism by He Peng Fei, Veerakumar Arumugam, Aleksander Góra, Vitali Lipik

“…Moreover, spectral emissivity of fabrics with additives are relatively high at peak human IR emission wavelength (8-14 µm). As a key signal molecule that is involved in certain physiological pathways, nitric oxide (NO) generation was assessed by co-culturing with human skeletal muscle cells (HMSCs). …”
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Unravelling the Methylene Blue Adsorption Mechanism on Doped and Nondoped Polyaniline: A Combined Molecular Modeling and Experimental Investigation by Souad Djellali, Amani Touati, Abderrahmane Semmeq, Maya Kebaili, Michael Badawi, Adrián Bonilla-Petriciolet

“…Equilibrium adsorption studies with nondoped PANI revealed a fast removal of the dye molecules where the equilibrium adsorption was reached after 45 minutes. …”
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Essential oils modulate virulence phenotypes in a multidrug-resistant pyomelanogenic Pseudomonas aeruginosa clinical isolate by Jayalekshmi Haripriyan, Christy Rose Binu, Nitasha D Menon, Muralidharan Vanuopadath, Malavika B. Hari, N Namitha, Kesiya Binoy, Anil Kumar, Bipin G. Nair, Victor Nizet, Geetha B. Kumar

“…Additionally, downregulation of the expression of virulence genes regulated by quorum sensing (QS) and a decrease in levels of the QS signaling molecule, C12-HSL, were also observed. The EO treatment inhibited the survival of U804 in human blood and increased survival of C. elegans, a whole animal model of pathogenesis. …”
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Hemoglobin I from Lucina pectinata on Collagen Scaffold: A Prospective Hydrogen Sulfide Scavenger by Jennifer Vargas Santiago, Anibal Quintana Cheeseborough, Juan López-Garriga

“…Hydrogen sulfide (H2S), independently of being a toxic gas with a characteristic smell of rotten eggs, is a crucial signaling molecule with significant physiological functions. …”
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Acinetobacter baumannii Lipopolysaccharide Influences Adipokine Expression in 3T3-L1 Adipocytes by Yuka Unno, Yoshinori Sato, Satoshi Nishida, Akiyo Nakano, Ryuichi Nakano, Tsuneyuki Ubagai, Yasuo Ono

“…This study suggests that A. baumannii-derived LPS functions as a signaling molecule that impacts the inflammatory function of white adipose tissue on the level of gene expression.…”
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Maternal Serum Fractalkine Concentrations in Pregnancies Complicated by Fetal Growth Restriction by Ecem Berfun Toprak Sager, Ibrahim Kale, Hakan Sager, Aysegul Ozel, Murat Muhcu

“…The role of the fractalkine molecule in the development of fetal growth restriction remains to be clarified in future studies with larger series. …”
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Real-world assessment of effectiveness and safety of filgotinib in 286 patients with ulcerative colitis in 9 UK centres by David Young, Sohail Rahmany, Deborah Taylor, Emma Davis, Michael Colwill, Sonia Kalyanji Mehta, Roisin Campbell, Karl Hazel, Karishma Sethi-Arora, Susan Ritchie, Ashley I Heinson, Helen Moyses, Keith Bodger, Emma Johnston, Lucy Hicks, Anjan Dhar, Jimmy Limdi, Rachel Cooney, John Paul Seenan, Kamal Patel, Alissa Walsh, Fraser Cummings

“…The median age at filgotinib initiation was 38 (IQR 27–51) years, 64% were men and median disease duration was 5.1 (IQR 1.9–10.5) years; 56% had previous exposure to advanced therapies (biologics and small molecule) and 6% previously received tofacitinib. At the post-induction review, clinical response and remission were achieved in 65% and 51% of patients, respectively. …”
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Serum Levels of Irisin and Omentin-1 in Breast Neoplasms and Their Association with Tumor Histology by Grigorios Panagiotou, Sofia Triantafyllidou, Basil C. Tarlatzis, Eleni Papakonstantinou

“…When combined with omentin-1, irisin concentration was associated with the presence of breast malignancy. This molecule’s role as a potential diagnostic and/or prognostic agent in breast malignancies warrants further investigation in larger prospective studies.…”
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Determination of Tributyltin in Seafood Based on Magnetic Molecularly Imprinted Polymers Coupled with High-Performance Liquid Chromatography-Inductively Coupled Plasma Mass Spectro... by Hua Yang, Huien Zhang, Xiao Yan Zhu, Shi Da Chen, Lijun Liu, Daodong Pan

“…First, the functional monomer (methacrylic acid, MAA) was modified on the surface of Fe3O4, which was then polymerized with the template molecule (tributyltin, TBT), cross linking agent (ethylene glycol dimethacrylate, EGDMA), and porogen (acetonitrile), hereby successfully preparing Fe3O4@MIPs prone to specifically identify TBT. …”
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CD226 Deficiency Alleviates Murine Allergic Rhinitis by Suppressing Group 2 Innate Lymphoid Cell Responses by Yang Xie, Yuan Zhang, Tianxiao Zhu, Jingchang Ma, Chujun Duan, Lu Yang, Tingting Wang, Ran Zhuang, Ka Bian, Lianjun Lu

“…CD226 is a costimulatory molecule associated with inflammatory response and is mainly expressed on T cells, natural killer cells, and monocytes. …”
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Structural Alteration, Hydration Stability, Heavy Metal Removal Efficiency, and Montmorillonite Porosity Fate by Coupling the Soil Solution pH and a Thermal Gradient by Chadha Mejri, Walid Oueslati, Abdesslem Ben Haj Amara

“…Thermal analysis allowed us to develop theoretical models describing the decrease of the water molecule amounts as a function of the increase in temperature and soil solution pH. …”
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Synthesis, Structural Characterization, and Electrochemical Studies of New Oxovanadium(V) Complexes Derived from 2-Furanoylhydrazon Derivatives by Rahman Bikas, Hassan Hosseini-Monfared, Erwann Jeanneau, Behrouz Shaabani

“…The oxo group and one methanol molecule occupy the apical sites. In the complexes 1, 2, and 3 the conformation of 2-furanyl oxygen atom relative to the carbohydrazide oxygen atom is s-anti, s-anti/s-syn, and s-syn at 293 K, respectively. …”
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TransLeish: Identification of membrane transporters essential for survival of intracellular Leishmania parasites in a systematic gene deletion screen by Andreia Albuquerque-Wendt, Ciaran McCoy, Rachel Neish, Ulrich Dobramysl, Çağla Alagöz, Tom Beneke, Sally A. Cowley, Kathryn Crouch, Richard J. Wheeler, Jeremy C. Mottram, Eva Gluenz

“…A total of 312 protein components of small molecule carriers, ion channels and pumps were identified and targeted in a CRISPR-Cas9 gene deletion screen in the promastigote form, yielding 188 viable null mutants. …”
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Impact of Endurance Exercise Training on Biomarkers of Aortic Endothelial Damage in Diabetic Rats by Mahtab Fouladi, Maryam Mahmoudabady, Zahra Gholamnezhad, Sadegh Shabab, Saeed Niazmand, Hossein Salmani

“…After 6 weeks, biochemical parameters in serum and oxidative stress markers and mRNA expression of endothelial nitric oxide synthase (eNOS), lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), and intercellular adhesion molecule-1 (ICAM-1) in aorta tissue were assessed. …”
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E-Selectin/AAV Gene Therapy Promotes Myogenesis and Skeletal Muscle Recovery in a Mouse Hindlimb Ischemia Model by Antoine J. Ribieras, Yulexi Y. Ortiz, Yan Li, Nga T. Le, Carlos T. Huerta, Francesca A. Voza, Hongwei Shao, Roberto I. Vazquez-Padron, Zhao-Jun Liu, Omaida C. Velazquez

“…E-selectin is an adhesion molecule that mediates cell recruitment during neovascularization. …”
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Metastatic brain tumors: from development to cutting‐edge treatment by Guilong Tanzhu, Liu Chen, Jiaoyang Ning, Wenxiang Xue, Ce Wang, Gang Xiao, Jie Yang, Rongrong Zhou

“…Moreover, preclinical agents often need to cross the blood–brain barrier to achieve high intracranial concentrations, including small‐molecule inhibitors, nanoparticles, and peptide drugs. …”
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Structures of Astaxanthin and Their Consequences for Therapeutic Application by Tatas Hardo Panintingjati Brotosudarmo, Leenawaty Limantara, Edi Setiyono, Heriyanto

“…We highlight the effect of structural modification of astaxanthin molecules on the bioavailability and biological activity. …”
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Carbon Nanomaterials in the Treatment of Infectious Bone Defects and Wound Scars after Wushu Fractures by Shenghui Wei, Lei Zou, Xu Hu, Qiuming Li

“…In this paper, carbon nanofibers containing doxycycline, a small molecule protease inhibitor, were prepared by simple blending. …”
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Orphan nuclear receptor NR2E3 is a new molecular vulnerability in solid tumors by activating p53 by Yidan Wang, Todd G. Kroll, Linhui Hao, Zhi Wen

“…Moreover, we show that the small-molecule agonist of NR2E3, 11a, penetrates tumor mass of uterine cancer patients and increases p53 activation. …”
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