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- Physics 1
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1581
Experimental Study on the Pore Structure of Middle- and Low-Rank Coal and Its Influence on Methane Adsorption
Published 2022-01-01“…Further analysis shows that the order of the tortuosity of the coal sample is WZ>XJ>PDS, which means that the WZ sample has a large pore tortuosity, a long channel for methane molecules to diffuse into the internal pores of the coal sample, and large diffusion resistance. …”
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1582
Influence of Sample Preparation on SERS Signal
Published 2025-01-01“…Carbendazim (MBC), a commonly used fungicide from the benzimidazole group, was applied in this study as a probe molecule to understand the influence of sample preparation on the SERS (surface-enhanced Raman scattering) signal. …”
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1583
Levamisole, as a viral vaccine adjuvant, induces robust host defense through the modulation of innate and adaptive immune responses
Published 2025-01-01“…However, the currently used vaccines for FMD have several limitations, including induction of humoral rather than cellular immune responses.MethodsTo overcome these shortcomings, we assessed the efficacy of levamisole, a small-molecule immunomodulator, as an adjuvant for the FMD vaccine. …”
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1584
STK3 Suppresses Ovarian Cancer Progression by Activating NF-κB Signaling to Recruit CD8+ T-Cells
Published 2020-01-01“…Serine/threonine protein kinase-3 (STK3) is a critical molecule of the Hippo pathway but little is known about its biological functions in the ovarian cancer development. …”
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1585
Plant Sources, Extraction Methods, and Uses of Squalene
Published 2018-01-01“…Squalene (SQ) is a natural compound, a precursor of various hormones in animals and sterols in plants. It is considered a molecule with pharmacological, cosmetic, and nutritional potential. …”
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1586
Robust methoxy-based covalent organic frameworks membranes enable efficient near-molecular-weight selectivity
Published 2025-01-01“…A three-stage cascade process was used to fractionate binary molecules with varying charges, achieving a separation factor of 26.7 for heterogeneous charge molecules. …”
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1587
A study on blocking store-operated Ca2+ entry in pulmonary arterial smooth muscle cells with xyloketals from marine fungi
Published 2017-12-01“…Moreover, the molecular docking study of xyloketal A with activation region of the stromal interaction molecule (STIM) 1 and the calcium release-activated calcium modulator (ORAI) 1 (STIM1-ORAI1) protein complex, the key domain of SOCE, revealed that xyloketal A exhibited a noncovalent interaction with the key residue lysine 363 (LYS363) in the identified cytosolic regions in STIM1-C. …”
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1588
ENL mutation and AML: a new model that reveals oncogenic condensate's function in leukemogenesis
Published 2025-01-01“…Furthermore, they show that small‐molecule inhibition of the acetyl‐binding activity displaces ENL mutant condensates from oncogenic target loci, and this inhibitor significantly impairs the onset and progression of AML driven by mutant ENL in vivo.…”
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1589
Exploring the anticancer potential of Hewittia malabarica through phytochemical analysis and molecular docking study
Published 2025-02-01“…The identification of the active molecule/s in the chloroform extract will serve as drug candidate for colorectal carcinoma. …”
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1590
The Many Faces of Human Leukocyte Antigen-G: Relevance to the Fate of Pregnancy
Published 2014-01-01“…HLA-G is primarily expressed in placenta and plays multifaceted roles during pregnancy, both as a soluble and a membrane-bound molecule. Its immunomodulatory functions involve interactions with different immune cells and possibly regulation of cell migration during placental development. …”
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1591
Association between extracellular DNA levels, markers of inflammation and left ventricular mass index in children with chronic kidney disease
Published 2025-01-01“…In univariate analysis, levels of interleukin-6 (IL-6), antimicrobial peptide cathelicidin (LL-37), soluble vascular cell adhesion molecule-1 (VCAM-1) and left ventricular mass index (LVMI) were positively correlated with total exDNA and nc_exDNA concentrations. …”
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1592
Solvent solutions: comparing extraction methods for edible oils and proteins in a changing regulatory landscape. Part 1: Physical-properties☆
Published 2024-01-01“…Due to their hydroxyl group, alcohols (methanol, ethanol, isopropanol) exhibit only a modest affinity for non-polar lipids, though this affinity increases with the number of carbon atoms in the alcohol molecule. They demonstrate a higher efficacy in extracting polar lipids; however, this extraction process also extends to numerous non-lipidic molecules. …”
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1593
Insights into the mechanisms, regulation, and therapeutic implications of extracellular matrix stiffness in cancer
Published 2025-01-01“…The extracellular matrix (ECM) is a significant tumor component that serves various functions, including mechanical support, TME regulation, and signal molecule generation. The quantity and cross‐linking status of ECM components are crucial factors in tumor development, as they determine tissue stiffness and the interaction between stiff TME and cancer cells, resulting in aberrant mechanotransduction, proliferation, migration, invasion, angiogenesis, immune evasion, and treatment resistance. …”
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1594
Sensitization to nsLTP: A Retrospective Study in An Italian Pediatric Population over the Last Decade
Published 2023-01-01“…About 52% of the test population was sensitized to at least one LTP molecule. For all the LTPs analyzed, sensitization increased over time. …”
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1595
Triterpenoids from Chios Mastiha Resin Against MASLD—A Molecular Docking Survey
Published 2025-01-01“…The combination of active compounds from Chios mastiha rather than a single molecule may have a superior ability to control the intertwined MASLD metabolic pathways.…”
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1596
Inference of a three-gene network underpinning epidermal stem cell development in Caenorhabditis elegans
Published 2025-02-01“…Here, we integrate experimental data, mathematical modeling, and statistical inference to investigate this network, focusing on three core transcription factors (TFs), namely ELT-1, EGL-18, and CEH-16. We use single-molecule FISH to quantify TF mRNA levels in single seam cells of wild-type and mutant backgrounds across four early larval stages. …”
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1597
Adsorption removing various basic nitrogen compounds from model diesel over allochroic silica gel
Published 2018-12-01“…The N–Co bond between Co in allochroic silica gel and N atom in the basic nitrogen compounds molecule played a significant role. Furthermore, the allochroic silica gel could be easily regenerated by its adsorption denitrogenation performance for quinoline and pyridine by using calcination once or several times, except aniline. …”
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1598
Elevation of Glucose 6-Phosphate Dehydrogenase Activity Induced by Amplified Insulin Response in Low Glutathione Levels in Rat Liver
Published 2016-01-01“…These findings indicated that elevation of the G6PD activity in low GSH levels was caused by amplified insulin response for expression of the enzyme and accelerated turnover rate of the enzyme molecule.…”
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1599
Assembly of oleosin during efficient extraction: Altering the sequence of defatting solvents
Published 2025-01-01“…Oleosin consisted of two district types, with oleosin-H (16–17 kDa) being the part of the molecule with limited water solubility, while oleosin-L (13–14 kDa) constituted the non-soluble part. …”
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1600
Effect of Isopropanol on Microstructure and Activity of TiO2 Films with Dominant {001} Facets for Photocatalytic Degradation of Bezafibrate
Published 2014-01-01“…Photoluminescence (PL) technique was used for the detection of produced hydroxyl radicals (•OH) on the surface of UV-illuminated TiO2 using terephthalic acid as probe molecule. The photocatalytic degradation intermediates of bezafibrate were analyzed by an ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), and accordingly the degradation pathways were proposed.…”
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