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  1. 1581

    Experimental Study on the Pore Structure of Middle- and Low-Rank Coal and Its Influence on Methane Adsorption by Gaini Jia, Ming Yang, Xuebo Zhang, Lei Liu

    Published 2022-01-01
    “…Further analysis shows that the order of the tortuosity of the coal sample is WZ>XJ>PDS, which means that the WZ sample has a large pore tortuosity, a long channel for methane molecules to diffuse into the internal pores of the coal sample, and large diffusion resistance. …”
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  2. 1582

    Influence of Sample Preparation on SERS Signal by Isabela Bianchi-Carvalho, Marcelo José dos Santos Oliveira, Cibely Silva Martin, Santiago Sánchez-Cortés, Carlos José Leopoldo Constantino

    Published 2025-01-01
    “…Carbendazim (MBC), a commonly used fungicide from the benzimidazole group, was applied in this study as a probe molecule to understand the influence of sample preparation on the SERS (surface-enhanced Raman scattering) signal. …”
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  3. 1583

    Levamisole, as a viral vaccine adjuvant, induces robust host defense through the modulation of innate and adaptive immune responses by Gang Sik Kim, Dong Yun Kwak, Hyeong Won Kim, Seokwon Shin, Mi-Kyeong Ko, Seong Yun Hwang, So Hui Park, Dong Hyeon Kim, Jong-Hyeon Park, Su-Mi Kim, Min Ja Lee

    Published 2025-01-01
    “…However, the currently used vaccines for FMD have several limitations, including induction of humoral rather than cellular immune responses.MethodsTo overcome these shortcomings, we assessed the efficacy of levamisole, a small-molecule immunomodulator, as an adjuvant for the FMD vaccine. …”
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  4. 1584

    STK3 Suppresses Ovarian Cancer Progression by Activating NF-κB Signaling to Recruit CD8+ T-Cells by Xiangyu Wang, Fengmian Wang, Zhi-Gang Zhang, Xiao-Mei Yang, Rong Zhang

    Published 2020-01-01
    “…Serine/threonine protein kinase-3 (STK3) is a critical molecule of the Hippo pathway but little is known about its biological functions in the ovarian cancer development. …”
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  5. 1585

    Plant Sources, Extraction Methods, and Uses of Squalene by M. Azalia Lozano-Grande, Shela Gorinstein, Eduardo Espitia-Rangel, Gloria Dávila-Ortiz, Alma Leticia Martínez-Ayala

    Published 2018-01-01
    “…Squalene (SQ) is a natural compound, a precursor of various hormones in animals and sterols in plants. It is considered a molecule with pharmacological, cosmetic, and nutritional potential. …”
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  6. 1586

    Robust methoxy-based covalent organic frameworks membranes enable efficient near-molecular-weight selectivity by Yanqing Xu, Jiaqi Xiong, Chenfei Lin, Yixiang Yu, Qite Qiu, Junbin Liao, Huimin Ruan, Arcadio Sotto, Jiangnan Shen

    Published 2025-01-01
    “…A three-stage cascade process was used to fractionate binary molecules with varying charges, achieving a separation factor of 26.7 for heterogeneous charge molecules. …”
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  7. 1587

    A study on blocking store-operated Ca2+ entry in pulmonary arterial smooth muscle cells with xyloketals from marine fungi by Zhou Jie-Bin, Sun Ying-Ying, Zheng Ying-Lin, Yu Chu-Qin, Lin Hua-Qing, Pang Ji-Yan

    Published 2017-12-01
    “…Moreover, the molecular docking study of xyloketal A with activation region of the stromal interaction molecule (STIM) 1 and the calcium release-activated calcium modulator (ORAI) 1 (STIM1-ORAI1) protein complex, the key domain of SOCE, revealed that xyloketal A exhibited a noncovalent interaction with the key residue lysine 363 (LYS363) in the identified cytosolic regions in STIM1-C. …”
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  8. 1588

    ENL mutation and AML: a new model that reveals oncogenic condensate's function in leukemogenesis by Zhong Fan, Yanan Jiang, Xiaotian Zhang

    Published 2025-01-01
    “…Furthermore, they show that small‐molecule inhibition of the acetyl‐binding activity displaces ENL mutant condensates from oncogenic target loci, and this inhibitor significantly impairs the onset and progression of AML driven by mutant ENL in vivo.…”
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  9. 1589

    Exploring the anticancer potential of Hewittia malabarica through phytochemical analysis and molecular docking study by Shiji Thozhukkad Moosaripparambil, Kannan Vadakkadath Meethal

    Published 2025-02-01
    “…The identification of the active molecule/s in the chloroform extract will serve as drug candidate for colorectal carcinoma. …”
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  10. 1590

    The Many Faces of Human Leukocyte Antigen-G: Relevance to the Fate of Pregnancy by Mette Dahl, Snezana Djurisic, Thomas Vauvert F. Hviid

    Published 2014-01-01
    “…HLA-G is primarily expressed in placenta and plays multifaceted roles during pregnancy, both as a soluble and a membrane-bound molecule. Its immunomodulatory functions involve interactions with different immune cells and possibly regulation of cell migration during placental development. …”
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  11. 1591

    Association between extracellular DNA levels, markers of inflammation and left ventricular mass index in children with chronic kidney disease by Ylva Tranæus Lindblad, Ľubomíra Tóthová, Peter Celec, Karolina Kublickiene, Peter Bárány, Milan Chromek

    Published 2025-01-01
    “…In univariate analysis, levels of interleukin-6 (IL-6), antimicrobial peptide cathelicidin (LL-37), soluble vascular cell adhesion molecule-1 (VCAM-1) and left ventricular mass index (LVMI) were positively correlated with total exDNA and nc_exDNA concentrations. …”
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  12. 1592

    Solvent solutions: comparing extraction methods for edible oils and proteins in a changing regulatory landscape. Part 1: Physical-properties☆ by Carré Patrick, Berthold Sebastian, Piofczyk Thomas, Bothe Sarah, Hadjiali Sara

    Published 2024-01-01
    “…Due to their hydroxyl group, alcohols (methanol, ethanol, isopropanol) exhibit only a modest affinity for non-polar lipids, though this affinity increases with the number of carbon atoms in the alcohol molecule. They demonstrate a higher efficacy in extracting polar lipids; however, this extraction process also extends to numerous non-lipidic molecules. …”
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  13. 1593

    Insights into the mechanisms, regulation, and therapeutic implications of extracellular matrix stiffness in cancer by Ximo Zhang, Abdullah Al‐Danakh, Xinqing Zhu, Dan Feng, Linlin Yang, Haotian Wu, Yingying Li, Shujing Wang, Qiwei Chen, Deyong Yang

    Published 2025-01-01
    “…The extracellular matrix (ECM) is a significant tumor component that serves various functions, including mechanical support, TME regulation, and signal molecule generation. The quantity and cross‐linking status of ECM components are crucial factors in tumor development, as they determine tissue stiffness and the interaction between stiff TME and cancer cells, resulting in aberrant mechanotransduction, proliferation, migration, invasion, angiogenesis, immune evasion, and treatment resistance. …”
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  14. 1594

    Sensitization to nsLTP: A Retrospective Study in An Italian Pediatric Population over the Last Decade by Cristiana Indolfi, Giulio Dinardo, Angela Klain, Marcella Contieri, Giuseppina Rosaria Umano, Fabio Decimo, Salvatore Abbadessa, Carolina Vitulano, Giorgio Ciprandi, Michele Miraglia del Giudice

    Published 2023-01-01
    “…About 52% of the test population was sensitized to at least one LTP molecule. For all the LTPs analyzed, sensitization increased over time. …”
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  15. 1595

    Triterpenoids from Chios Mastiha Resin Against MASLD—A Molecular Docking Survey by Nataša Milošević, Maja Milanović, Milica Medić Stojanoska, Varomyalin Tipmanee, Ilias Smyrnioudis, George V. Dedoussis, Nataša Milić

    Published 2025-01-01
    “…The combination of active compounds from Chios mastiha rather than a single molecule may have a superior ability to control the intertwined MASLD metabolic pathways.…”
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  16. 1596

    Inference of a three-gene network underpinning epidermal stem cell development in Caenorhabditis elegans by Alicja Brożek, Arianna Ceccarelli, Andreas Christ Sølvsten Jørgensen, Mark Hintze, Vahid Shahrezaei, Michalis Barkoulas

    Published 2025-02-01
    “…Here, we integrate experimental data, mathematical modeling, and statistical inference to investigate this network, focusing on three core transcription factors (TFs), namely ELT-1, EGL-18, and CEH-16. We use single-molecule FISH to quantify TF mRNA levels in single seam cells of wild-type and mutant backgrounds across four early larval stages. …”
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  17. 1597

    Adsorption removing various basic nitrogen compounds from model diesel over allochroic silica gel by Xin Hong, Yunhe Li, Chang Gao, Yonghua Zhao, Ke Tang

    Published 2018-12-01
    “…The N–Co bond between Co in allochroic silica gel and N atom in the basic nitrogen compounds molecule played a significant role. Furthermore, the allochroic silica gel could be easily regenerated by its adsorption denitrogenation performance for quinoline and pyridine by using calcination once or several times, except aniline. …”
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  18. 1598

    Elevation of Glucose 6-Phosphate Dehydrogenase Activity Induced by Amplified Insulin Response in Low Glutathione Levels in Rat Liver by Misako Taniguchi, Nobuko Mori, Chizuru Iramina, Akira Yasutake

    Published 2016-01-01
    “…These findings indicated that elevation of the G6PD activity in low GSH levels was caused by amplified insulin response for expression of the enzyme and accelerated turnover rate of the enzyme molecule.…”
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  19. 1599

    Assembly of oleosin during efficient extraction: Altering the sequence of defatting solvents by Yu Li, Yuqian Qiao, Yuxuan Zhu, Wangyang Shen, Weiping Jin, Dengfeng Peng, Qingrong Huang

    Published 2025-01-01
    “…Oleosin consisted of two district types, with oleosin-H (16–17 kDa) being the part of the molecule with limited water solubility, while oleosin-L (13–14 kDa) constituted the non-soluble part. …”
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  20. 1600

    Effect of Isopropanol on Microstructure and Activity of TiO2 Films with Dominant {001} Facets for Photocatalytic Degradation of Bezafibrate by Murtaza Sayed, Fu Pingfeng, Hasan M. Khan, Pengyi Zhang

    Published 2014-01-01
    “…Photoluminescence (PL) technique was used for the detection of produced hydroxyl radicals (•OH) on the surface of UV-illuminated TiO2 using terephthalic acid as probe molecule. The photocatalytic degradation intermediates of bezafibrate were analyzed by an ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), and accordingly the degradation pathways were proposed.…”
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