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  1. 141

    Discovery of the bacterial HslV protease activators as lead molecules with novel mode of action by Aurangzeb Sana, Aurongzeb Muhammad, Shamim Shahbaz, Rashid Yasmeen, Khan Khalid Mohammed, Aziz Tariq, Alharbi Metab, Alasmari Abdullah F.

    Published 2025-02-01
    “…This study not only presents more potent small non-peptide activators of the HslV protease but also enhances the understanding regarding the mechanism of HslVU complex activation via small non-peptidic molecules.…”
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    Role of Toll-Like Receptors and Their Downstream Molecules in the Development of Nonalcoholic Fatty Liver Disease by Kouichi Miura, Ekihiro Seki, Hirohide Ohnishi, David A. Brenner

    Published 2010-01-01
    “…This paper will highlight the recent progress on the study of TLR signaling and their downstream molecules in the development of NAFLD.…”
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    Cell adhesion molecules involved in the leukocyte recruitment induced by venom of the snake Bothrops jararaca by Stella R. Zamuner, Catarina F. P. Teixeira

    Published 2002-01-01
    “…Therefore, the role of the adhesion molecules intercellular adhesion molecule-1 (ICAM-1), LECAM-1, CD18, leukocyte function-associated antigen-1 (LFA-1) and platelet endothelial cell adhesion molecule-1 (PECAM-1) on the BjV-induced neutrophil accumulation and the correlation with release of LTB4, TXA2, tumor necrosis factor-α, interleukin (IL)-1 and IL-6 have been investigated. …”
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  8. 148

    Surface Heterogeneity at the Solid-Gas Interface of Hydrophilic Solids Modified by Water-Repellent Molecules by F. Villiéras, M. Chamerois, J. Yvon, J.M. Cases

    Published 2007-10-01
    “…The surface heterogeneity of a hydrophilic calcium carbonate (calcite) at the solid-gas interface was studied before and after modification by the adsorption of different amounts of a water-repellent molecule (WRM). The surface heterogeneity was analysed using nitrogen, argon and water as molecular probes. …”
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  9. 149

    Identification of a binding site for small molecule inhibitors targeting human TRPM4 by Babatunde Ekundayo, Prakash Arullampalam, Christian E. Gerber, Anne-Flore Hämmerli, Sabrina Guichard, Mey Boukenna, Daniela Ross-Kaschitza, Martin Lochner, Jean-Sebastien Rougier, Henning Stahlberg, Hugues Abriel, Dongchun Ni

    Published 2025-01-01
    “…We found that the small molecules NBA and IBA were bound in a pocket formed between the S3, S4, and TRP helices and the S4-S5 linker of TRPM4. …”
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    Traffic Control of Bacteria-Derived Molecules: A New System of Host-Bacterial Crosstalk by Hiroaki Konishi, Mikihiro Fujiya, Yutaka Kohgo

    Published 2013-01-01
    “…This paper highlights the intestinal trafficking systems of bacteria-derived molecules that affect the bacterial functions and modulate epithelial signaling cascades. …”
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  12. 152

    High-throughput single-molecule quantification of individual base stacking energies in nucleic acids by Jibin Abraham Punnoose, Kevin J. Thomas, Arun Richard Chandrasekaran, Javier Vilcapoma, Andrew Hayden, Kacey Kilpatrick, Sweta Vangaveti, Alan Chen, Thomas Banco, Ken Halvorsen

    Published 2023-02-01
    “…Here, we use a Centrifuge Force Microscope for high-throughput single molecule experiments to measure stacking energies between adjacent bases. …”
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  13. 153

    A White-Light-Emitting Small Molecule: Synthesis, Crystal Structure, and Optical Properties by Sin-Kai Fang, Hsing-Yang Tsai, Jiun-Wei Hu, Kew-Yu Chen

    Published 2014-01-01
    “…A white-light-emitting small molecule (1) was synthesized and characterized by single-crystal X-ray diffraction. …”
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  14. 154

    Polyamines Interaction with Gaseous Signaling Molecules for Resilience Against Drought and Heat Stress in Plants by Nidhi, Noushina Iqbal, Nafees A. Khan

    Published 2025-01-01
    “…The key regulators of plant stress responses include polyamines (PAs) and gaseous signaling molecules (GSM), such as hydrogen sulfide (H<sub>2</sub>S), nitric oxide (NO), methane (CH<sub>4</sub>), carbon monoxide (CO), carbon dioxide (CO<sub>2</sub>), and ethylene (ET). …”
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    Single-cell morphological tracking of cell states to identify small-molecule modulators of liver differentiation by Rebecca E. Graham, Runshi Zheng, Jesko Wagner, Asier Unciti-Broceta, David C. Hay, Stuart J. Forbes, Victoria L. Gadd, Neil O. Carragher

    Published 2025-02-01
    “…These findings could significantly advance research on liver cell regeneration mechanisms and facilitate the development of cell-based and small-molecule therapies.…”
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