Sirtuin 1 and Aging Theory for Chronic Obstructive Pulmonary Disease by V. Conti, G. Corbi, V. Manzo, G. Pelaia, A. Filippelli, A. Vatrella

“…Recently it was suggested that Sirtuin 1 (SIRT1), an antiaging molecule involved in the response to oxidative stress and chronic inflammation, is implicated in both development and progression of COPD. …”
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Role of Fractalkine/CX3CL1 and Its Receptor in the Pathogenesis of Inflammatory and Malignant Diseases with Emphasis on B Cell Malignancies by Elisa Ferretti, Vito Pistoia, Anna Corcione

“…Fractalkine/CX3CL1, the only member of the CX3C chemokine family, exists as a membrane-anchored molecule as well as in soluble form, each mediating different biological activities. …”
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Nutritional Ketosis and Mitohormesis: Potential Implications for Mitochondrial Function and Human Health by Vincent J. Miller, Frederick A. Villamena, Jeff S. Volek

“…Furthermore, the ketone β-hydroxybutyrate (BHB), which is elevated during nutritional ketosis to levels no greater than those resulting from fasting, acts as a signaling molecule in addition to its traditionally known role as an energy substrate. …”
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Implication of Fructans in Health: Immunomodulatory and Antioxidant Mechanisms by Elena Franco-Robles, Mercedes G. López

“…Fructans are nonreducing carbohydrates composed of fructosyl units and terminated by a single glucose molecule. These carbohydrates may be straight or branched with varying degrees of polymerization. …”
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Prediction of influence of helical structure on shape memory behavior of thermosetting resin useing molecular dynamics simulation by Shuaijiang Ma, Qi Zhang, Xuyan Li, Jilei Xu, Ping Chen

“…We propose introducing helical structure molecules into thermosetting resin matrix to investigate the influence of helical structure molecules on the shape memory properties of the resin matrix. …”
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The role of short-chain fatty acid in metabolic syndrome and its complications: focusing on immunity and inflammation by Wenqian Yu, Wenqian Yu, Siyuan Sun, Siyuan Sun, Qiang Fu

“…Short-chain fatty acid (SCFA), an organismal energy donor, has recently been demonstrated in an increasing number of studies to be an important molecule in ameliorating immuno-inflammation, an important causative factor of Mets, and to improve lipid distribution, blood glucose, and body weight levels in animal models of Mets. …”
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Corrosion Inhibition of Mild Steel in HCl by Isolated Compounds of Riccinus Communis (L.) by Rinki Goel, W. A. Siddiqi, Bahar Ahmed, J. Hussan

“…The inhibition was assumed to occur via adsorption of the inhibitor molecule on the metal surface. In the 298- 308 K temperature range, the C1, C2 and C3 adsorption follows Langmuir isotherm model. …”
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Using Protein Painting Mass Spectrometry to Define Ligand Receptor Interaction Sites for Acetylcholine Binding Protein by Alexandru Graur, Natalie Erickson, Nadine Kabbani

“…We describe how the use of small molecule dyes can be optimized to uncover contact sites for ligand–protein interactions based on MS detection. …”
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2-Cys Peroxiredoxins: Emerging Hubs Determining Redox Dependency of Mammalian Signaling Networks by Jinah Park, Sunmi Lee, Sanghyuk Lee, Sang Won Kang

“…However, recent evidence demonstrates that typical 2-Cys peroxiredoxins play key signal regulatory roles in the various signaling networks by interacting with or residing near a specific redox-sensitive molecule. These discoveries help reveal the redox signaling landscape in mammalian cells and may further provide a new paradigm of therapeutic approaches based on redox signaling.…”
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Stigmasterol Modulates Allergic Airway Inflammation in Guinea Pig Model of Ovalbumin-Induced Asthma by Aaron Opoku Antwi, David Darko Obiri, Newman Osafo

“…Overexpression of serum vascular cell adhesion molecule-1 (VCAM-1) and ovalbumin-specific immunoglobulin E (OVA sIgE) elicited by ovalbumin sensitization and challenge was significantly controlled with stigmasterol. …”
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Gigantomastia and Macroprolactinemia Responding to Cabergoline Treatment: A Case Report and Minireview of the Literature by Fatma Dilek Dellal, Didem Ozdemir, Cevdet Aydin, Gulfem Kaya, Reyhan Ersoy, Bekir Cakir

“…Although macroprolactin is considered as a biologically inactive molecule, some authorities suggest treatment in symptomatic cases. …”
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Optical Energy Transfer Mechanisms: From Naphthalene to Biacetyl in Liquids and from Pyrazine to Biacetyl by Fuat Bayrakceken, Korkut Yegin, Erdal Korkmaz, Yakup Bakis, Bayram Unal

“…Biacetyl is the simplest molecule among a wide range of -dicarbonyl compounds, which is important for photophysics and photochemistry applications.…”
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GSK-3𝜷: A Bifunctional Role in Cell Death Pathways by Keith M. Jacobs, Sandeep R. Bhave, Daniel J. Ferraro, Jerry J. Jaboin, Dennis E. Hallahan, Dinesh Thotala

“…Secondary to the role of GSK-3β in various diseases including Alzheimer’s disease, inflammation, diabetes, and cancer, small molecule inhibitors of GSK-3β are gaining significant attention. …”
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Variation of gene ratios in mock communities constructed with purified 16S rRNA during processing by Georges Mikhael Nammoura Neto, René Peter Schneider

“…The RT reaction yielded one copy of cDNA per rRNA molecule for Pa, Bc and Sa but only 2/3 of the expected cDNA from 16S rRNAs of Bs and Kp. …”
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Pharmacological targeting of caspase-8/c-FLIPL heterodimer enhances complex II assembly and elimination of pancreatic cancer cells by Corinna König, Nikita V. Ivanisenko, Vladimir A. Ivanisenko, Dagmar Kulms, Inna N. Lavrik

“…Recently, we have developed the first-in class small molecule, FLIPinB, which specifically targets the key regulator of extrinsic apoptosis, the protein c-FLIPL, in the caspase-8/c-FLIPL heterodimer. …”
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Low‐rank and sparse reconstruction for fast diffusion nuclear magnetic resonance spectroscopy by Di Guo, Jiaying Zhan, Yirong Zhou, Zhangren Tu, Zifei Zhang, Zhong Chen, Xiaobo Qu

“…Abstract Nuclear magnetic resonance with diffusion‐ordered spectroscopy (DOSY) serves as an important analytical tool to non‐destructively separate a molecule from a compound in medicine and chemistry. …”
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Study of Millimeter-Wave Rotational Spectra ofTrioxane in Ground, v(A), v1(E) = 1 and v2(E) = 1 States by Masoud Motamedi, Najmehalsadat Khademi

“…The millimeter-wave rotational spectra of the ground and excited vibrational states v(A), v1 (E) =1 and v2 (E ) =1 of the oblate symmetric top molecule, (CH2O)3, have been analyzed again. The B0 = 5273.25747MHz, D J = 1.334547 kHz, D Jk = -2.0206 kHz, H J (-1.01 mHz), H JK (-3.80 mHz), and HKJ (4.1 mHz) have been determined for ground state. …”
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Decarburization of ferrochrome and high alloy steels with optimized gas and slag phases towards improved Cr retention by Wang H., Nzotta M.M., Teng L., Seetharaman S.

“…The kinetic analysis showed that the mass transfer is effective due to the production of 2CO gas molecules from one CO2 molecule during the reaction which will improve the stirring of the bath. …”
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A DAG Scheduling Scheme on Heterogeneous Computing Systems Using Tuple-Based Chemical Reaction Optimization by Yuyi Jiang, Zhiqing Shao, Yi Guo

“…TMSCRO also applies the concept of constrained critical paths (CCPs), constrained-critical-path directed acyclic graph (CCPDAG) and super molecule for accelerating convergence. In this paper, we have also conducted simulation experiments to verify the effectiveness and efficiency of TMSCRO upon a large set of randomly generated graphs and the graphs for real world problems.…”
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Both Maturation and Survival of Human Dendritic Cells are Impaired in the Presence of Anergic/Suppressor T Cells by L. Frasca, C. Scottà, G. Lombardi, E. Piccolella

“…Indeed, MHC and costimulatory molecule up-regulation was inhibited in immature DC, whereas apoptotic phenomena were favored in mature DC and consequently in responder T cells. …”
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