Tag7 (PGLYRP1) Can Induce an Emergence of the CD3+CD4+CD25+CD127+ Cells with Antitumor Activity by T. N. Sharapova, E. A. Romanova, L. P. Sashchenko, D. V. Yashin

“…These cells can induce lysis of HLA-negative tumor cell lines. The Hsp70 stress molecule on the surface of the tumor cells is used as a recognition target, while the Tag7 protein on the lymphocyte membrane acts as a receptor for Hsp70. …”
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Role of CEACAM1, ECM, and Mesenchymal Stem Cells in an Orthotopic Model of Human Breast Cancer by Sridhar Samineni, Carlotta Glackin, John E. Shively

“…Carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) is a morphogen in an in vitro model for lumen formation and plays a similar role in breast epithelial cells implanted in humanized mammary fat pads in NOD-SCID mice. …”
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Characterization of the Complete Mitochondrial Genome of Kaloula mediolineata (Microhylidae, Anura) and Its Phylogenetic Analysis by Thu-Thao Thi Huynh, Minh Trong Quang, Hoang Danh Nguyen

“…Results: The mitochondrial genome of K. mediolineata is a circular DNA molecule of 16,812 base pairs, encoding 37 genes, including 13 protein-coding genes, 22 transfer RNA genes, 2 ribosomal RNA genes, and a control region. …”
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A Recent Overview of 1,2,3-Triazole-Containing Hybrids as Novel Antifungal Agents: Focusing on Synthesis, Mechanism of Action, and Structure-Activity Relationship (SAR) by Mahrokh Marzi, Mojtaba Farjam, Zahra Kazeminejad, Abolfazl Shiroudi, Amin Kouhpayeh, Elham Zarenezhad

“…The bioactive compounds demonstrated antitubercular, antibacterial, anti-inflammatory, anticancer, antioxidant, antiviral, and antidiabetic properties. This heterocycle molecule, in particular, with one or more 1,2,3-triazole cores has been found to have the most powerful antifungal effects. …”
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RHEOLOGICAL PROPERTIES OF INDOLIC ALKALOIDS OBTAINED FROM NATURAL PRODUCTS by Ana-Maria Neculai, Anamaria Niculescu, Iuliana Cristea

“…The foul-smelling indole molecule is the building block for various natural and chemical products. …”
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Melatonin in Hypoxic-Ischemic Brain Injury in Term and Preterm Babies by Justyna Paprocka, Marek Kijonka, Beata Rzepka, Maria Sokół

“…Melatonin efficacy, low toxicity, and ability to readily cross through the blood-brain barrier make it a promising molecule. A very interesting thing is the difference between the half-life of melatonin in preterm neonates (15 hours) and adults (45-60 minutes). …”
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Role of neuroimmunomodulation by vagus nerve stimulation in rheumatoid arthritis: Are we heading towards a drug-free era? by Prasan Deep Rath, Swetal Pandey, Rahul Bisaralli

“…Another mechanism is the neural inflammatory reflex that regulates innate and adaptive immune responses and also inhibits the production of a vital inflammatory therapeutic target molecule, known as tumor necrosis factor, for RA. This review discusses the multifactorial and multidimensional interactions between neurons and immune cells, the mechanisms of the nervous system which are responsible for the regulation of inflammation, the impact of cholinergic pathways on inflammation, and the evidence supporting the role of various bioelectronic devices in vagus nerve stimulation.…”
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Development of an Environmentally Friendly Resist-Removal Process Using Wet Ozone by Hideo Horibe, Yousuke Goto

“…Using TOF-SIMS, we clarified that the molecule of cresol novolak resin was destroyed and carbonized by ion implantation.…”
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The Role of 5-Lipoxygenase and Leukotrienes in Shock and Ischemia-Reperfusion Injury by Antonietta Rossi, Carlo Pergola, Salvatore Cuzzocrea, Lidia Sautebin

“…In particular, several data indicate that LTs regulate neutrophil trafficking in damaged tissue in shock and ischemia-reperfusion, mainly through the modulation of adhesion molecule expression. This concept may provide new insights into the interpretation of the protective effect of 5-LO inhibition, which may be useful in the therapy of pathological conditions associated with septic and nonseptic shock and ischemia-reperfusion injury.…”
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Singlet spin order in spin pairs coupled via non-bonded interactions by Giuseppe Pileio, Dolnapa Yamano, Craig D. Eccles, Graham J. Tizzard, Sam Thompson

“…This form of order, which, in this example molecule, is more than an order of magnitude longer than longitudinal order, has the potential to be useful in magnetic resonance imaging and molecular tracing experiments, because of the lack of endogenous fluorine in the human body and the high sensitivity achievable in 19F NMR.…”
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Inhibitory Effects of Antimicrobial Peptides on Lipopolysaccharide-Induced Inflammation by Yue Sun, Dejing Shang

“…Antimicrobial peptides (AMPs) are usually small molecule peptides, which display broad-spectrum antimicrobial activity, high efficiency, and stability. …”
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Structural and Optoelectronic Properties of CdSe Tetrapod Nanocrystals for Bulk Heterojunction Solar Cell Applications by Nguyen Tam Nguyen Truong, Thao Phuong Ngoc Nguyen, Chinho Park

“…The surface capping molecule, octylphosphonic acid, was replaced with butylamine after the particle synthesis. …”
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Complete mitochondrial genome and phylogenetic analysis of the Atrato slider, Trachemys medemi (Testudines, Emydidae) by Sebastián Cuadrado-Ríos, Mario Vargas-Ramírez, Christian Kehlmaier, Uwe Fritz

“…The mitochondrial genome is a circular DNA molecule of 16,711–16,810 bp in size, with 60.9% AT content. …”
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In Vivo Molecular Imaging in Retinal Disease by Fang Xie, Wenting Luo, Zhongyu Zhang, Dawei Sun

“…To detect endothelial injury at the early and reversible stage of adhesion molecule upregulation, some novel imaging agents that target retinal endothelial molecules were generated. …”
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On the Nature of Interplay among Major Flexibility Channels in Molecular Rotors by M. S. A. Abdel-Mottaleb

“…Such a study may give information on how the molecule could be externally modified/fixed to yield a desired effect, i.e., more fluorescence or more nonradiative decay.…”
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Influence of Polymorphism on Glycosylation of Serum Amyloid A4 Protein by Toshiyuki Yamada, Jyunji Sato, Kazuhiko Kotani, Masafumi Tanaka

“…These findings suggest that the changes in protein structures alter the efficiency of glycosylation in the SAA4 molecule. The functional implication of this should be of interest.…”
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Ceramic-Supported Alginate Adsorbent for the Removal of Heavy Metal Ions by Chrysoula P. Athanasekou, George E. Romanos, Andreas A. Sapalidis, Nick K. Kanellopoulos

“…In this context, the aim was to develop hybrid sorbents with an enhanced stability and adsorption capacity obtained by grafting the bio-molecule onto the substrate. Such chemical modification included grafting two different types of silanes onto the external surface and pores of γ-alumina, followed by chemical bonding of the alginate with the characteristic groups of the silane molecules involved. …”
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GSK-3β at the Intersection of Neuronal Plasticity and Neurodegeneration by Tomasz Jaworski, Ewa Banach-Kasper, Katarzyna Gralec

“…Mouse models with neuron-selective expression or deletion of GSK-3β present behavioral and cognitive abnormalities, positioning this protein kinase as a key signaling molecule in normal brain functioning. Furthermore, mouse models with defective GSK-3β activity display distinct structural and behavioral abnormalities, which model some aspects of different neurological and neuropsychiatric disorders. …”
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Carboxylic Acid Bioisosteres in Medicinal Chemistry: Synthesis and Properties by Kato Bredael, Silke Geurs, Dorien Clarisse, Karolien De Bosscher, Matthias D’hooghe

“…Despite its common use as a key functionality in drugs, its presence in a lead molecule is often associated with poor pharmacokinetic properties and toxicity. …”
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The known unknowns of the Hsp90 chaperone by Laura-Marie Silbermann, Benjamin Vermeer, Sonja Schmid, Katarzyna Tych

“…We highlight three fundamental open questions, reviewing the current state of the field for each, and discuss new opportunities, including single-molecule technologies, to answer the known unknowns of the Hsp90 chaperone.…”
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