Biosynthesis inhibition of miR-142-5p in a N 6-methyladenosine-dependent manner induces neuropathic pain through CDK5/TRPV1 signaling by Jinshi Li, Yang Guo, Chen Zhu, Dongxu Wang, Yuan Li, Xiaotong Hao, Linyan Cao, Yiting Fan, Bo Fang

“…According to database predictions, miR-142-5p, identified as a shared upstream molecule of TRPV1 and CDK5, exhibited downregulation following induction by NP. …”
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Label-free determination of diffusion coefficients at the nanoscale through modelling of the Surface Plasmon Resonance signal. by Gabriele Antonio Zingale, Irene Pandino, Damiano Calcagno, Maria Luisa Perina, Nunzio Tuccitto, Giuseppe Grasso

“…Surface plasmon resonance (SPR) is normally used to measure the kinetic parameters of biomolecular interactions between a molecule immobilized on a gold surface and another one flowing in a microfluidic channel above the surface. …”
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La mercatique transatlantique d’un végétal psychoactif : le guaraná entre remède et aliment (1840-1921) by Bastien Beaufort

“…During this period the plant became the object of a strong scientific interest on the other side of the Atlantic, especially in France and Germany, with the identification of its active molecule, the guaranine. Once isolated this alkaloid was largely distributed as a remedy thanks to the support of numerous scientists and merchants in the European drugstore network. …”
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Immune Regulation and Antitumor Effect of TIM-1 by Peng Du, Ruihua Xiong, Xiaodong Li, Jingting Jiang

“…T cells play an important role in antitumor immunity, and the T cell immunoglobulin domain and the mucin domain protein-1 (TIM-1) on its surface, as a costimulatory molecule, has a strong regulatory effect on T cells. …”
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Photodegradation of Lincomycin in Aqueous Solution

“…The mineralization of the molecule led to the formation of sulfate, ammonium, and nitrate ions.…”
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Molecular-Dynamics Simulation of Self-Diffusion of Molecular Hydrogen in X-Type Zeolite by Xiaoming Du

“…The self-diffusion coefficients decrease with increasing pressure due to packing of sorbate-sorbate molecules which causes frequent collusion among hydrogen molecules in pores and increase with increasing temperature because increasing the kinetic energy of the gas molecules enlarges the mean free path of gas molecule. …”
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The Role of RaxST, a Prokaryotic Sulfotransferase, and RaxABC, a Putative Type I Secretion System, in Activation of the Rice XA21-Mediated Immune Response by Pamela C. Ronald

“…These observations suggest a model where RaxST sulfates a molecule that contains a leader peptide, which is cleaved by the peptidase domain of the RaxB protein and secreted outside the bacterial cell by the RaxABC T1SS.…”
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Sugar Alcohols, Caries Incidence, and Remineralization of Caries Lesions: A Literature Review by Kauko K. Mäkinen

“…Based on known molecular parameters of simple dietary alditols, it is conceivable to predict that their efficacy in caries prevention will follow the homologous series, that is, that the number of OH-groups present in the alditol molecule will determine the efficacy as follows: erythritol≥xylitol>sorbitol. …”
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High-throughput Identification of Phage-derived Imaging Agents by Kimberly A. Kelly, Paul A. Clemons, Amy M. Yu, Ralph Weissleder

“…The new methodology should be useful in identifying phage hits and is extendable to other library screening methods such as small-molecule and nanoparticle libraries.…”
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Local Molecular Reactivity of the Colored Dansylglycine in Water and Dioxane Studied through Conceptual DFT by Juan Frau, Daniel Glossman-Mitnik

“…The study confirmed the results from previous works showing that the MN12SX density functional is the most appropriate in predicting the chemical reactivity of this molecule in both solvents.…”
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On the Adsorption of Chiral Propylene Oxide onto Pd(111): A DFT Study by A. Gil-Rebaza, D. Linares, G. Zgrablich

“…The adsorption energy varies over a wide range of values spanning the range from ca. 10–20 kcal/mol for both the inclination of the molecule with respect to the surface and the coverage.…”
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Adsorption of Tributyl Phosphate on Silica Gel by V.F. Sazonova, M.A. Kojemyak, O.V. Perlova

“…The increase in entropy was explained in terms of the mobility of the TBP molecules in the adsorptive layer arising from their replacement on the silica gel surface by water molecules derived from the aqueous medium.…”
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Design and synthesis of phenylthiophosphoryl dichloride derivatives and evaluation of their antitumour and anti-inflammatory activities by Chunyun Xu, Na Yang, Haichun Yu, Xiaojing Wang

“…Tumours and inflammation are serious risks to human health and are importantly regulated by the gas signalling molecule hydrogen sulphide. In this work, we report the rational design and synthesis of H2S donor molecules based on phenylthiophosphoryl dichloride nuclei and assess their efficacy against tumours and inflammation. …”
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Spectral Characterization and Crystal Structure of 1,2-Bis-(1H-benzimidazol-2-yl)-ethane Dihydrochloride by Aydin Tavman, Cigdem Sayil

“…Owing to the anti conformations of –CH2– groups, the entire molecule is relatively flat. H1-NMR spectra of 1 show AA′XX′ system characteristics.…”
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Bacterial Glycosulphatases and Sulphomucin Degradation by Anthony M Roberton, Damian P Wright

“…At present this term can only be qualitatively related to the percentage of sulphate in the mucin molecule, which makes the term difficult to use in a biochemical and functional sense. …”
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M5-brane prongs, string soliton bound states and wall-crossing by Varun Gupta, K. Narayan

“…Then we impose boundary conditions on the scalars near the string soliton cores. This leads to a molecule-like equilibrium structure of two non-parallel string solitons at fixed transverse separations, with the M5-brane "prong" deformations comprising two "spikes", each shaped like a ridge. …”
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RP105-Negative B Cells in Systemic Lupus Erythematosus by Syuichi Koarada, Yoshifumi Tada

“…RP105 (CD180), the toll-like receptor- (TLR-) associated molecule, is expressed on normal B cells. However, RP105-negative B cells increase in peripheral blood from patients with active SLE. …”
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Fabrication of submicrosized imprinted spheres attached polypropylene membrane using “” molecular imprinting method for targeted separation by Minjia Meng, Yonghai Feng, Yan Liu, Xiaohui Dai, Jianming Pan, Yongsheng Yan

“…The submicrosized imprinted polypropylene microfiltration membrane (SIPM) for salicylic acid (SA) was prepared by water-in-oil emulsion polymerization method and two-dimensional imprinting method based on polypropylene microfiltration membrane with salicylic acid as template molecule, 4-vinyl pyridine as functional monomer, Span 80 as emulsifier, toluene as the oil phase, ethyleneglycol dimethacrylate as cross-linking agent, and 2,2′-azobis (2-methylpropionitrile) as initiator. …”
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Recent Status on Lactate Monitoring in Sweat Using Biosensors: Can This Approach Be an Alternative to Blood Detection? by Leonardo Messina, Maria Teresa Giardi

“…Recent studies have shown that lactate is a molecule that plays an indispensable role in various physiological cellular processes, such as energy metabolism and signal transductions related to immune and inflammatory processes. …”
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Study on the Interaction of Serum Albumin and Micromolecule Compounds by Rui Huang, Zhi-Ning Xia, Min Yi, Bo-Lin Liu

“…Fluorescence spectrometry is a classical and conventional technique widely used in interaction investigation, which takes serum albumin as the fluorescence source while micro-molecule compound as the quencher. With analyzing the properties of serum albumin and its amino acids, deficiencies in the conventional fluorescence spectrometry became obvious: information expressed by the conventional technique was not sufficient to represent the entire interaction. …”
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