On the Resistance-Harary Index of Graphs Given Cut Edges by Hongzhuan Wang, Hongbo Hua, Libing Zhang, Shu Wen

“…Each vertex in the graph represents the molecule and each edge represents the bond between the atoms. …”
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HSV-1 Encephalitis in an Elderly Man Receiving Ibrutinib for Waldenstrom’s Macroglobulinemia by Mark R. Wallace

“…Though ibrutinib has proven to be a revolutionary new small molecule agent, and has relatively minimal toxicity as compared to traditional chemotherapy, infections have emerged as a major complication of therapy. …”
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Capture réglementaire en temps de pandémie by Samira Guennif

“…In the midst of the covid-19 pandemic, the Food and Drug Administration (FDA) published in March the orphan drug status granted to remdesivir, a molecule patented by Gilead as a treatment for the new coronavirus. …”
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Theoretical Study of CO Adsorption on Perfect and Defective Gold Surfaces by Yingying Wang, Bing Xu, Wanyi Shen

“…The results clearly show that the activity of Au surfaces towards CO adsorption is attributable to the presence of low-coordinated gold atoms to which the molecule binds. The results may enrich the understanding of CO adsorption on Au surfaces.…”
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Clinical Perspectives - Biologics in IBD: What's All the Fuss? by Hillary Steinhart

“…This article examines the evidence behind the use of biologic therapies such as anti-tumour necrosis factor-alpha, interleukin-10, interleukin-11, anti-integrin antibody and antisense intercellular adhesion molecule-1 oligonucleotide.…”
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Endometriosis, Angiogenesis and Tissue Factor by Graciela Krikun

“…We have employed a novel immunoconjugate molecule known as Icon and were able to eradicate endometrial lesions in a mouse model of endometriosis without affecting fertility. …”
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Methyl 2-amino-4-(morpholin-4-yl)benzo[d]thiazole-6-carboxylate tetartohydrate by Erik Uran, Andrej Emanuel Cotman, Matic Lozinšek

“…The title compound, C13H15N3O3S·0.25H2O, crystallizes in the triclinic space group P1 and features four organic molecules in the asymmetric unit alongside one water molecule. …”
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Augmentation of NKT and NK cell-mediated cytotoxicity by peptidoglycan monomer linked with zinc by Ines Mrakovcic-Šutic, Biserka Radoševic-Stašic, Marija Šimin, Damir Muhvic, Daniel Rukavina

“…Background: Peptidoglycan monomer (PGM), which was originally prepared by biosynthesis from culture fluids of penicillin-treated Brevibacterium divaricatum, is an immunostimulator, the activities of which might be improved by addition of zinc (Zn) to the basic molecule.…”
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Synthesis of Novel Peptide Dendrimers PDL-GB2 and PDL-G2 by Lin Yunzhu, Weng Lingling, Qi Qingrong

“…In this paper, novel peptide dendrimers PDL-GB2 and PDL-G2 were prepared according to divergent procedure with four-orientation molecule as the core and L-lysine as the branch unit. …”
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Blastocyst-Derived Lactate as a Key Facilitator of Implantation by Kathryn H. Gurner, David K. Gardner

“…While historically perceived as a metabolic waste product, lactate serves as a signaling molecule which facilitates the invasion of surrounding tissues by cancers and promotes blood vessel formation during wound healing. …”
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Febuxostat and Increased Dialysis as a Treatment for Severe Tophaceous Gout in a Hemodialysis Patient by Lynda Ann Frassetto, Suzanne Gibson

“…Uric acid is also a small non-protein-bound molecule and therefore easily dialyzable. Here, we present the case of an anuric hemodialysis patient with severe tophaceous gout who regained some renal function and whose gout burden significantly decreased resulting in marked improvement in functional status using a new gout medication, febuxostat, and increased frequency of dialysis.…”
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Synthesis of High-Thermal Stable Titanium Dioxide Nanoparticles by M. Rashidzadeh

“…The final products were characterized by N2 adsorption, X-ray diffraction, FT-IR, and TEM and tested in a photoreactor using fluorescien as model molecule. For thermal stability investigation, the sample prepared at 300∘C was heated up to 800, 850, and 900∘C, the XRD results showed that the synthesized anatase phase was stable up to 850∘C. …”
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Theoretical Analysis of Superphenalene Using Different Kinds of VDB Indices by K. Julietraja, Ammar Alsinai, Abdu Alameri

“…Superphenalene is a large polycyclic aromatic hydrocarbon molecule which has been quickly gaining importance as a building block for alternate energy providers due to its photovoltaic properties. …”
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Determining interaction directionality in complex biochemical networks from stationary measurements by N. Leibovich

“…We introduce a method to infer the directionality within this network only from a “snapshot” of the abundances of the relevant molecules. We examine the validity of the approach for different properties of the system and the data recorded, such as the molecule’s level variability, the effect of sampling and measurement errors. …”
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The promising role of nanopore sequencing in cancer diagnostics and treatment by Xinming Su, Qingyuan Lin, Bin Liu, Chuntao Zhou, Liuyi Lu, Zihao Lin, Jiahua Si, Yuemin Ding, Shiwei Duan

“…The utilization of nanopore sequencing offers a powerful means of detecting these alterations due to its unique capacity for long single-molecule sequencing. In the context of DNA analysis, nanopore sequencing excels in identifying structural variations (SVs), copy number variations (CNVs), gene fusions within SVs, and mutations in specific genes, including those involving DNA modifications and DNA adducts. …”
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Activated Growth Factor From Platelets as Treatment for Diabetic Retinopathy Through Antioxidant-Oxidative Stress Pathway by Amin R, Hidayat R, Maritska Z, Putri TW

“…Advanced glycation end products (AGEs), p38 mitogen activated protein kinase (p38 MAPK), nuclear factor-κβ (NF-κβ), reactive oxygen species (ROS), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), superoxide dismutase (SOD) and vascular endothelial growth factor (VEGF) was assessed using enzyme linked immunoassay (ELISA). …”
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Synthesis and structural characterization of s-triazine derivatives and their photophysical properties by Hessa H. Al-Rasheed, Sizwe J. Zamisa, Ihab Shawish, Assem Barakat, Ayman El-Faham, Beatriz G. de la Torre, Fernando Albericio, Anamika Sharma

“…In 2 and 3, intermolecular N—H…O were observed between the H7 atom of the amine group and O4 atom of the methanol molecule. In 4, the same intramolecular C—H…N hydrogen bonds mentioned in 2 and 3 were found. …”
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Acute and chronic effects of physical exercise on atherosclerosis, kynurenine pathway, endothelial function and inflammation in patients with coronary artery disease: a clinical tr... by Eliete Bouskela, Gabriela Andrade Paz, Marcus VDS Rangel, Caio Luan Farias, André Luiz Conveniente Soares, Erica Langner, Tatiana Teixeira, Patrícia M L Dutra, Paulo Farinatti, Maria das Graças C Souza, Juliana P Borges

“…Levels of KP metabolites (TRP, KYN, kynurenic acid and quinolinic acid), inflammatory cytokines (interleukin-6, tumour necrosis factor-alpha and interferon-gamma), T-cell subpopulations and soluble adhesion molecules (soluble P-selectin, soluble vascular cell adhesion molecule-1 and soluble intercellular adhesion molecule-1) will be assessed via ELISA, flow cytometry and multiplex assays, respectively. …”
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IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential by Feiya Sheng, Mi Li, Jia-Mei Yu, Si-Yu Yang, Liang Zou, Guan-Jun Yang, Le-Le Zhang, Le-Le Zhang

“…While most cytokines are actively synthesized within cells, IL-33 is produced passively in response to tissue damage or cell necrosis, indicating its role as a signaling molecule following cellular infection, stress, or trauma. …”
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<i>Pseudomonas aeruginosa pqs</i> Quorum Sensing Mediates Interaction with <i>Mycobacterium abscessus</i> In Vitro by Yun Long, Zhi Li, Menglu Li, Peiyi Lu, Yujia Deng, Pengyao Wu, Xue Li, Gangjian Qin, Jiamin Huang, Wenying Gao, Guobao Li, Tianyuan Jia, Liang Yang

“…Our study suggests that the <i>P. aeruginosa</i> PQS can serve as an interspecies signaling molecule to communicate with <i>Mycobacterium</i> and affect their physiology and virulence.…”
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