Interactions of Self-Assembled <i>Bletilla Striata</i> Polysaccharide Nanoparticles with Bovine Serum Albumin and Biodistribution of Its Docetaxel-Loaded Nanoparticles by Guangyuan Zhang, Jin Qiao, Xin Liu, Yuran Liu, Ji Wu, Long Huang, Danyang Ji, Qingxiang Guan

“…Docetaxel was encapsulated in nanoparticles at the small molecules or had an amorphous status. The inhibitory capability of DTX-loaded BSPs-SA nanoparticles against 4T1 tumor cells was superior to that of Duopafei^®. …”
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Metal‐Mediated Chlorine Transfer for Molten Salt‐Driven Thermodynamic Change on Silicon Production by Minjun Je, Jin Chul Kim, Jiyeon Kim, Sungho Kim, Sunmin Ryu, Jaegeon Ryu, Sang Kyu Kwak, Soojin Park

“…Above its melting temperature (Tm ≈ 192 °C), three AlCl3 molecules coordinate with each metal (M) atom (e.g., conventional Al and Mg, or even thermodynamically unfeasible Zn) to form metal‐AlCl3 complexes, M(AlCl3)3. …”
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Exploring the exoproteome of the parasitic nematode Anisakis simplex (s. s.) and its impact on the human host – an in vitro cross-talk proteomic approach by Robert Stryiński, Robert Stryiński, Ewa Fiedorowicz, Jesús Mateos, Aneta Andronowska, Elżbieta Łopieńska-Biernat, Mónica Carrera

“…While many studies have explored nematode biology and host interactions, the role of extracellular vesicles (EVs) as signaling molecules in parasitic nematodes is less understood.Materials and methodsTherefore, the proteins present in the EVs of A. simplex (s. s.) …”
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Crop protection by RNA interference: a review of recent approaches, current state of developments and use as of 2013 by Kirsten Germing, Cecilia Andrea Díaz Navarrete, Andreas Schiermeyer, Udo Hommen, Luise Zühl, Sebastian Eilebrecht, Elke Eilebrecht

“…Due to the assumed beneficial properties of RNA molecules, such as degradability or target specificity, RNAi technology receives increasing attention in the development of plant protection products, as evidenced by a steadily increasing number of publications. …”
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The helper strategy in vector-transmission of plant viruses by Di Mattia, Jérémy, Zeddam, Jean-Louis, Uzest, Marilyne, Blanc, Stéphane

“…Because of the importance of HC molecules in the vector-transmission of plant viruses, we here propose an exhaustive review of the field, of its historical perspective and most recent development. …”
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Dredging and sediment discharge in a river with floodplain. Physicochemical and microbiological effects in Paraná river by Maria Josefina Gonzalez, Stella Maris Gonzalez, Aldo Raul Paira, Pablo Agustín Collins

“…The variables measured in sediment and water samples were limnological parameters (e.g. conductivity, pH, dissolved oxygen, among others), heavy metal concentration, presence of biocides, hydrocarbon molecules, nutrients, sediment granulometry, Escherichia coli, Enterococcus, total coliforms, and heterotrophic bacteria. …”
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Alternative buffer systems in biopharmaceutical formulations and their effect on protein stability by Lebar Blaž, Zidar Mitja, Mravljak Janez, Šink Roman, Žula Aleš, Pajk Stane

“…The efficacy of histidine buffers in combating light stress might be attributed to the light-absorbing properties of histidine molecules. Our findings demonstrate that the development of biopharmaceutical formulations should not be confined to conventional buffer systems, as numerous alternative options exhibit comparable or even superior performance.…”
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Development of sustained-release extemporaneous moxifloxacin loaded commercial soft hydrogel contact lenses by Duy Toan Pham, Pratthana Chomchalao, Kunasin Bunneramit, Phurichaya Kladcharoen, Rossukon Khotcharrat, Waree Tiyaboonchai

“…Isothermally, the moxifloxacin molecules were adsorbed onto the contact lenses surfaces via physical adsorptions by weak interactions of van der Waals forces, ionic bonding, and hydrophobic interactions. …”
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Development of a prognostic model based on four genes related to exhausted CD8+ T cell in triple-negative breast cancer patients: a comprehensive analysis integrating scRNA-seq and... by Yulin Shi, Yang Yu, Jiahan Zhao, Linan Huang, Qingyang Wang, Qi Sun, Lijuan Liu, Changgang Sun

“…The model demonstrated robust predictive capability in both the TCGA cohort and an external cohort, with the low-risk group exhibiting elevated expression of immunological checkpoint molecules and immune cell infiltration, as well as better responses to immunotherapy and chemotherapy. …”
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EIF4A3-induced circ_0022382 promotes breast cancer cell progression through the let-7a-5p/PI3K/AKT/mTOR signaling pathway and SLC7A11 axis by Wei Liu, Wei Liu, Jun Zhang, Jiawen Zhang, Yu Ye, Jianqin Zhu, Qiwen Yu, Tao Li, Tao Li, Xiaochun Sun, Huabiao Chen, Huabiao Chen

“…Consistently, knockdown of circ_0022382 inhibited the growth of breast cancer cells in vivo.DiscussionCirc_0022382 and its related molecules may be effective targets for diagnosis or targeted therapy of breast cancer.…”
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Perspectives on Structural, Physiological, Cellular, and Molecular Responses to Desiccation in Resurrection Plants by Yathisha Neeragunda Shivaraj, Plancot Barbara, Bruno Gugi, Maïté Vicré-Gibouin, Azeddine Driouich, Sharatchandra Ramasandra Govind, Akash Devaraja, Yogendra Kambalagere

“…Current progress in “-omic” technologies has enabled quantitative monitoring of the plethora of biological molecules in a high throughput routine, making it possible to compare their levels between desiccation-sensitive and DT species. …”
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The search for microRNAs potentially involved in the selfrenewal maintaining of laboratory rat pluripotent stem cells by V. V. Sherstyuk, S. P. Medvedev, M. T. Ri, Y. V. Vyatkin, O. V. Saik, D. N. Shtokalo, S. M. Zakian

“…However, involvement of this class of noncoding RNAs and functions of individual molecules are poorly studied. The goal of this study was the search for the miRNAs potentially involved in the pluripotency maintaining and reprogramming of Rattus norvegicus cells. …”
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Quantitative fluorescent nanoparticle tracking analysis and nano‐flow cytometry enable advanced characterization of single extracellular vesicles by Danilo Mladenović, Joseph Brealey, Ben Peacock, Kairi Koort, Nataša Zarovni

“…The NTA's and nFCM's limits of detection (LoD) were evaluated at 21 and 9 Alexa Fluor 488 (AF488) molecules, respectively. To complement the limited quantification of markers expressed in a few copies per single EV, in‐line bulk fluorescence measurements with a plate reader were performed. …”
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<i>Tribulus terrestris</i> Fruit Extract: Bioactive Compounds, ADMET Analysis, and Molecular Docking with Penicillin-Binding Protein 2a Transpeptidase of Methicillin-Resistant <i>S... by Khalid J. Alzahrani

“…<i>Tribulus terrestris</i> is a rich source of bioactive molecules and thrives in Mediterranean and desert climate regions worldwide. …”
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Probiotic Bacterium-Derived p40, p75, and HM0539 Proteins as Novel Postbiotics and Gut-Associated Immune System (GAIS) Modulation: Postbiotic-Gut-Health Axis by Feray Gençer Bingöl, Duygu Ağagündüz, Ferenc Budán

“…Postbiotics are bioactive metabolites such as organic acids, peptides/proteins, cell wall components, functional enzymes, short-chain fatty acids, vitamins, and phenols. These molecules mediate many positive effects such as immunomodulatory, antimicrobial, and antioxidant effects. …”
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Fabrication of highly efficient quartz crystal microbalance ammonia sensor based on Cu-BTC nanocomposites by Kobra Vazirinezhad, Fatemeh Shariatmadar Tehrani, Sedigheh Zeinali, Maryam Tohidi

“…Metal-organic frameworks (MOFs), as a type of nanoporous material, have attracted great attention in the field of gas sensing due to their unique properties, such as high adsorption sites for gas molecules compared to other conventional sensing materials. …”
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Exploring target selectivity in designing and identifying PI3Kα inhibitors for triple negative breast cancer with fragment-based and bioisosteric replacement approach by Debojyoti Halder, Shreya Mukherjee, R. S. Jeyaprakash

“…Further induced fit docking (IFD) analysis, DFT analysis, and MD simulation were employed to establish that – Djh1 and Djh2 could act as potential hit molecules for selective inhibition of PI3Kα. Further bioisosteric replacement, docking analysis, and target selectivity analysis were performed with the bioisosteres. …”
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Preliminary characterisation of the spatial immune and vascular environment in triple negative basal breast carcinomas using multiplex fluorescent immunohistochemistry. by Elena A Takano, Metta K Jana, Luis E Lara Gonzalez, Jia-Min B Pang, Roberto Salgado, Sherene Loi, Stephen B Fox

“…In silico analysis confirmed higher numbers of tumour-infiltrating lymphocytes in basal breast cancers and that higher numbers were significantly associated with endothelial cell activation molecules, co-clustering with upregulated ICAM-1 and VCAM-1 amongst others. …”
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EGF-R is Expressed and AP-1 and NF-κ:B Are Activated in Stromal Myofibroblasts Surrounding Colon Adenocarcinomas Paralleling Expression of COX-2 and VEGF by Panagiotis A. Konstantinopoulos, Gerasimos P. Vandoros, Michalis V. Karamouzis, Maria Gkermpesi, Georgia Sotiropoulou-Bonikou, Athanasios G. Papavassiliou

“…Double immunostaining with a-smooth muscle actin and each antibody was done to verify the expression of these molecules in stromal myofibroblasts. Results: VEGF, p-Iκ:B-α, NF-κ:B, c-FOS, p-c-JUN, EGF-R and COX-2 were expressed in stromal myofibroblasts surrounding colon adenocarcinomas in the majority of cases. …”
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Comprehensive analysis of ceRNA Networks in UCEC: Prognostic and therapeutic implications. by Li Fan, Mengqiu Lan, Xiaohua Wei, Lili Wei, Liuhong Yang, Liuying Nong, Jiajia Wei, Jingjing Li, Wenjie Huang

“…Differential expression analysis was conducted using the DESeq2 package, identifying differentially expressed lncRNAs, miRNAs, and mRNAs (DElncRNAs, DEmiRNAs, and DEmRNAs). Key molecules were screened using LASSO regression, and a ceRNA network was constructed by predicting lncRNA-miRNA and miRNA-mRNA interaction, which were visualized with Cytoscape. …”
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