Resveratrol, Acetyl-Resveratrol, and Polydatin Exhibit Antigrowth Activity against 3D Cell Aggregates of the SKOV-3 and OVCAR-8 Ovarian Cancer Cell Lines by Simon J. Hogg, Kenny Chitcholtan, Wafaa Hassan, Peter H. Sykes, Ashley Garrill

“…This study demonstrates that resveratrol and its derivatives may inhibit growth of 3D cell aggregates of ovarian cancer cell lines via different signalling molecules. Resveratrol and its derivatives, therefore, warrant further in vivo evaluation to assess their potential clinical utility.…”
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Deciphering the Transcriptional Metabolic Profile of Adipose-Derived Stem Cells During Osteogenic Differentiation and Epigenetic Drug Treatment by Giulia Gerini, Alice Traversa, Fabrizio Cece, Matteo Cassandri, Paola Pontecorvi, Simona Camero, Giulia Nannini, Enrico Romano, Francesco Marampon, Mary Anna Venneri, Simona Ceccarelli, Antonio Angeloni, Amedeo Amedei, Cinzia Marchese, Francesca Megiorni

“…In this study, we employed the NanoString nCounter technology, an advanced multiplexed digital counting method of RNA molecules, to comprehensively characterize differentially expressed transcripts involved in metabolic pathways at distinct time points in osteogenically differentiating ASCs treated with or without the pan-DNMT inhibitor RG108. …”
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The Multifaceted Roles of MicroRNA-181 in Stem Cell Differentiation and Cancer Stem Cell Plasticity by Chun Yang, Rui Wang, Pierre Hardy

“…Stem cell differentiation and the generation of cancer stem cells are regulated by numerous molecules, including microRNAs (miRNAs). These miRNAs, particularly through the modulation of EMT-associated factors, play major roles in controlling the stemness of cancer stem cells. …”
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The Roles of MicroRNAs in the Regulation of Rice–Pathogen Interactions by Yanfeng Jia, Kai Wei, Jiawang Qin, Wenxue Zhai, Quanlin Li, Yalan Li

“…Among these strategies, plant microRNAs (miRNAs), endogenous single-stranded short non-coding RNA molecules, have emerged as promising candidates in coordinating plant–pathogen interactions. …”
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Guest-Host Interactions in Symmetrical Carboxy Heptamethine Cyanine Dyes-Titanium Dioxide Systems: Synthesis, Theoretical Calculations, Aggregation Properties, and Application in D... by Rodrigo da Costa Duarte, Matheus Costa de Oliveira, Josene Maria Toldo, Paulo Fernando Bruno Gonçalves, Marcos José Leite Santos, Fabiano Severo Rodembusch

“…Different approaches have been tested, aimed at reducing the H-aggregation and minimizing the competition between cyanine molecules and DCA for active sites of the host, thus improving solar cell efficiency. …”
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Phenotypic and Functional Changes in Peripheral Blood Natural Killer Cells in Crohn Disease Patients by Suzanne Samarani, Patrick Sagala, Prevost Jantchou, Guy Grimard, Christophe Faure, Colette Deslandres, Devendra K. Amre, Ali Ahmad

“…NK cells from the patients also expressed increased levels of different gut-homing integrin molecules and showed a history of increased recent degranulation events both constitutively and in response to their in vitro stimulation. …”
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First insight into temporal variation of digestive enzyme activities in flathead grey mullet (Mugil cephalus) during the ongrowing phase by Silvia Natale, Andrea Bertini, Enric Gisbert, Karl B. Andree, Elisa Benini, Dario Vallainc, Pier Paolo Gatta, Alessio Bonaldo, Luca Parma

“…Digestive enzymes break down the complex nutrients of food into easily absorbable molecules. Understanding their temporal variation during food transit through the gastrointestinal tract is crucial for developing effective nutritional strategies. …”
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Effects of Delta-Like Noncanonical Notch Ligand 1 Expression of Human Fetal Liver Hepatoblasts on Hematopoietic Progenitors by Jörg C. Gerlach, Robert L. Thompson, Bruno Gridelli, Eva Schmelzer

“…Dlk1- cells were cultured either without Dlk1+ hepatoblasts, in direct contact with hepatoblasts, or separated from hepatoblasts by a porous membrane in inserts to inhibit cell contact but allow free exchange of molecules. Expression of the hepatic and hematopoietic genes, colony forming unit potential of various hematopoietic progenitors, and cell numbers and types were investigated. …”
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Soybean and avocado unsaponifiables: a review of their potential use in the treatment of osteoarthritis by Ana Sabucedo-Suárez, Ana Sabucedo-Suárez, Mónica López-Peña, Mónica López-Peña, María Permuy, María Permuy, Fernando Muñóz, Fernando Muñóz

“…According to in vitro research, ASU affect the regulation of molecules related to OA, increasing structural elements like collagen and aggrecan and decreasing pro-inflammatory mediators. …”
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Adsorptive Removal of Rhodamine B Using Novel Adsorbent-Based Surfactant-Modified Alpha Alumina Nanoparticles by Thi Hai Yen Doan, Thi Phuong Minh Chu, Thi Diu Dinh, Thi Hang Nguyen, Thi Cam Tu Vo, Nhat Minh Nguyen, Bao Huy Nguyen, The An Nguyen, Tien Duc Pham

“…The electrostatic attraction between positive RhB molecules and negatively charged M1 surface controlled the adsorption that was evaluated by the surface charge change with zeta potential and adsorption isotherms. …”
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Hybridization of Aminoadamantanes with Cinnamic Acid Analogues and Elucidation of Their Antioxidant Profile by Maya Chochkova, Almira Georgieva, Tsvetelina Ilieva, Madlena Andreeva, Georgi Pramatarov, Nejc Petek, Petranka Petrova, Martin Štícha, Yavor Mitrev, Jurij Svete

“…Overall, the results suggest that the hybrids (4b2, 4c6, and 4a6) consisting of a caffeoyl moiety and lipophilic adamantane core endow the molecules with the higher antioxidant activity than their parent compound (caffeic acid), especially against LP. …”
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Antitumor activity of edible fishes (Channa striata and Anabas testudineus) and gastropods (Helix aspersa and Pila virens) rudimentary mucus against HT-29 cell line and its biochem... by Elumalai Devan, Hemavathi Maduraiveeran, Kavitha Raja, Arulvasu Chinnasamy, Govindan Sivalingam, Sathya Balaji, Vinoth Neelakandan, Sharon Agnita, Murugan Rajaram

“…Abstract Background The mucus from fish and gastropods contains a wide range of bioactive molecules with biomedical properties. The fish and gastropods were collected from Oragadam lake, Kanchipuram district, Tamil Nadu, India. …”
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Effects of asiaticoside on the model of gestational diabetes mellitus in HTR-8/svneo cells via PI3K/AKT pathway by Zhilan Hu, Ya Long, Xiangyue Li, Zhiqin Jia, Mingyan Wang, Xuemei Huang, Xiaolan Yu

“…The mRNA levels of PI3K, AKT2, mTORC1, and GLUT4 in PI3K/AKT signalling pathway were measured by RT-PCR, and the protein expressions of these signalling molecules were monitored by western blot.Results AS showed a promotion effect on the cell proliferation rate of HTR-8/Svneo cells, and 80 μmol/L AS with a treatment time of 48 h had no cytotoxicity. …”
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Conditioned Medium from Adipose-Derived Stem Cell Inhibits Jurkat Cell Proliferation through TGF-β1 and p38/MAPK Pathway by Xiuxia Wang, Yinmin Wang, Xianyu Zhou, Fei Liu

“…Western blotting was performed to identify potential signaling molecules involved in the ADSC-CM-induced inhibition of Jurkat cell proliferation. …”
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A Cornflower Extract Containing N-Feruloylserotonin Reduces Inflammation in Human Skin by Neutralizing CCL17 and CCL22 and Inhibiting COX-2 and 5-LOX by Christophe Carola, Andrew Salazar, Christin Rakers, Franck Himbert, Quoc-Tuan Do, Philippe Bernard, Joerg von Hagen

“…Thus, an in silico molecular modeling and a generic screening assay were developed to screen natural molecules binding and blocking these two chemokines. …”
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Physical, Physicochemical, Mechanical, and Sensory Properties of Bioplastics from Phosphate Acetylated Arenga Starches by Abdul Rahim, Safitri Dombus, Syahraeni Kadir, Muhardi Hasanuddin, Syamsuddin Laude, Jusman Aditya, Steivie Karouw

“…The PAAS bioplastics were characterized by FTIR, which confirmed the acetylation and crosslinking between the arenga starch molecules. Generally, the elongation at break of the PAAS bioplastics was higher than that of the NAS bioplastic, color of the PAAS bioplastics was more transparent and texture of the PAAS bioplastics surface was smoother than of the NAS bioplastic.…”
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Discovery of conserved peptide-MHC epitopes for directly alloreactive CD8+ T cells by Alexandra E. Hill, Eric T. Son, Moumita Paul-Heng, Chuanmin Wang, Shivanjali Ratnaseelan, Martina Denkova, Pouya Faridi, Asolina Braun, Anthony W. Purcell, Nicole A. Mifsud, Alexandra F. Sharland

“…Mass Spectrometry allied with in-vivo generation of activated alloreactive T cell populations and tetramer screening facilitates the identification of endogenous peptides that are directly recognised in complex with allogeneic Major Histocompatibility class I (MHC I) molecules by alloreactive CD8+ T cells. We had previously used this approach for the discovery of immunogenic self-peptides presented by the allomorph H-2Kb (Kb). …”
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Universal Synthesis of Core–Shell‐Structured Ordered Mesoporous Transition Metal Dichalcogenides/Metal Oxides Heterostructures with Active Edge Sites by Zhenliang Li, Yujian Rao, Zhehan Wang, Tuo Zhang, Guodong Wu, Litao Sun, Yuan Ren, Li Tao

“…Theoretical study reveals that the strong adsorption capacity of WS2/WO3 heterostructure and edge sites of WS2 for NO2 molecules and the high charge transfer between them contribute to high selectivity and sensitivity of the sensor. …”
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Effect of treated palm fibers on the mechanical properties of compressed earth bricks stabilized by alkali‐activated binder‐based natural pozzolan by Rolande Aurelie Tchouateu Kamwa, Joseph Bikoun Mousi, Sylvain Tome, Juvenal Giogetti Deutou Nemaleu, Martine Gérard, Marie‐Annie Etoh, Jacques Etame

“…The Fourier transform infrared spectra revealed the effectiveness of the fibers in sorption water molecules. Moreover, optical examination reveals that the binder utilized completely wraps the fibers. …”
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Innovative epitopes in Staphylococcal Protein-A an immuno-informatics approach to combat MDR-MRSA infections by Pengjun Zhou, Pengjun Zhou, Xing Shi, Jinquan Xia, Yifei Wang, Shaowei Dong

“…Predicted epitopes underwent docking studies with HLA molecules to evaluate binding properties. In-silico analyses confirmed the antigenicity, promiscuity, and non-glycosylated nature of the selected epitopes.ResultsSeveral T and B cell epitopes within SpA were identified, showcasing high binding affinities and extensive population coverage. …”
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