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  1. 4201

    Identification of Key Genes and Pathways Associated with Age-Related Macular Degeneration by Junyu Zhang, Yu Zhou

    Published 2020-01-01
    “…As expected, several ophthalmic disease-related molecules, including RHO, PDE6A, 3′,5′-cyclic-GMP phosphodiesterase, and G protein alpha, were in the central nodes of disease network. …”
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  2. 4202

    Clinical Manifestation and Phylogenetic Analysis of Peste des Petits Ruminants in Local Iraqi Breed Sheep in Al-Diwaniyah Province by Khalefa A. Mansour, Muthanna H. Hussain, Saad H. Al-Husseiny, Asaad J. Abid, Qassim H. Kshash

    Published 2024-01-01
    “…Steric hindrance or protein shape change from Valine’s extended side chain may impact folding, stability, functionality, and interactions with other molecules. Furthermore, phylogenetic analysis showed that the Nigerian strain (MN271586) was most similar to our Iraqi strain, with 100% identity and coverage. …”
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  3. 4203

    Fluorescence Imaging Analysis of Upstream Regulators and Downstream Targets of STAT3 in Melanoma Precursor Lesions Obtained from Patients Before and After Systemic Low-Dose Interfe... by Amanda Pfaff Smith, John M. Kirkwood, Howard D. Edington, Drazen M. Jukic, Daniel L. Farkas, Dorothea Becker

    Published 2003-01-01
    “…To determine possible changes in the level of expression of these molecules in atypical nevi, excised before and after 3 months of systemic low-dose IFN-α treatment, newly designed optical imaging software was used to quantitate the captured fluorescent hybridization signals on a cell-by-cell basis and across an entire nevus section. …”
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  4. 4204

    Advances in therapies using mesenchymal stem cells and their exosomes for treatment of peripheral nerve injury: state of the art and future perspectives by Fatima Aldali, Chunchu Deng, Mingbo Nie, Hong Chen

    Published 2025-11-01
    “…The latter are nano-sized extracellular vesicles containing bioactive molecules such as proteins, microRNA, and messenger RNA derived from parent mesenchymal stem cells. …”
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  5. 4205

    Physiological and metabolome characterization of Amaranthus hybridus L. grown under cypermethrin stress: an insight of Jasmonic acid treatment by Arun Kumar, Pradeep Kumar Yadav, Anita Singh

    Published 2025-02-01
    “…CYP at R1 dose induced hormesis, while R2 was toxic, elevating the production of ROS molecules (H2O2, SOR, MDA). JA application upregulated the antioxidant activity of SOD, POD, APX, GST, DHAR, GSH, and proline to alleviate oxidative stress and improve growth indicators, including shoot length, leaf area, chlorophyll content, Fv/Fm ratio, and biomass. …”
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  6. 4206
  7. 4207

    Antioxidant Peptide Derived from Spirulina maxima Suppresses HIF1α-Induced Invasive Migration of HT1080 Fibrosarcoma Cells by Won Suk Kim, Won Kyo Jung, Sun Joo Park

    Published 2015-01-01
    “…Moreover, CoCl2-induced HIF1α expression was associated with an increase in the expression of molecules downstream of β-integrin, such as N-cadherin, vimentin, and β-catenin. …”
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  8. 4208

    Carotenoids Inhibit Fructose-Induced Inflammatory Response in Human Endothelial Cells and Monocytes by Ping Lin, Qian Ren, Qin Wang, Jiali Wu

    Published 2020-01-01
    “…We examined the monocyte adhesion to endothelial cells (ECs) and relevant endothelial adhesion molecules. Chemokine and proinflammatory cytokine production as well as intracellular oxidative stress were also assessed in fructose-stimulated ECs and monocytes. …”
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  9. 4209

    B-doped nano-hydroxyapatite facilitates proliferation and differentiation of osteoblasts by Qiao Kang, Wenhao Wang, Shengtao Wu, Ganggang Hu

    Published 2025-01-01
    “…B-nHAp significantly upregulated the expressions of marker molecules related to hBMSC proliferation and differentiation. …”
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  10. 4210

    Effect of Dietary Cholesterol, Phytosterol, and Docosahexaenoic Acid on Astaxanthin Absorption and Retention in Rainbow Trout by Yang Jin, Keshuai Li, Jon Olav Vik, Marie Hillestad, Rolf Erik Olsen

    Published 2024-01-01
    “…As a hydrophobic carotenoid, the absorption of Ax can be modulated by other lipid molecules in the diet. The present study explored the effect of three lipids, cholesterol (CH), phytosterol (PS), and docosahexaenoic acid (DHA) on Ax absorption, transport, and retention in rainbow trout. …”
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  11. 4211

    Diagnostic Test to Identify Parkinson’s Disease from the Blood Sera of Chinese Population: A Cross-Sectional Study by Guangan Tong, Pingping Zhang, Wenbin Hu, Kun Zhang, Xianwen Chen

    Published 2022-01-01
    “…The investigation revealed that serum and CSF exosomal miRNA molecules are definitive biomarkers for PD with proper specificity and sensitivity. …”
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  12. 4212

    Hydrogen reaction rate modeling based on convolutional neural network for large eddy simulation by Quentin Malé, Corentin J. Lapeyre, Nicolas Noiray

    Published 2025-01-01
    “…This is particularly challenging since $ {\mathrm{H}}_2 $ molecules diffuse much faster than heat, leading to large variations in burning rates, thermodiffusive instabilities at the subfilter scale, and complex turbulence-chemistry interactions. …”
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  13. 4213

    Effects of feeding different proportions of steam-flaked corn-based starter on growth performance, immunity and serum metabolism of pre-weaned Simmental calves by Kangyu Yao, Yu Gao, Liang Yang, Min Yang, Xiuyu Wu, Xinyu Zhang, Zhengke Lv, Wei Shao, Yong Wei, Wanping Ren

    Published 2025-01-01
    “…Compared to control, 31 metabolites differed in SFC33 group, mostly up-regulated, including glycerophospholipids, linoleic/arachidonic acid metabolism, cholesterol pathway molecules, L-glutamine in multiple pathways, and mannose in fructose/mannose metabolism.DiscussionIn summary, feeding 33% steam-flaked corn-based starter can improve the growth performance, enhance immunity, and improve sugars, lipids, and proteins metabolism of pre-weaned Simmental calves.…”
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  14. 4214

    Tratamiento farmacológico de la obesidad. Situación actual y nuevos tratamientos by Julio Sagredo Pérez, Gonzalo Allo Miguel

    Published 2025-01-01
    “…The high potency and safety of these drugs has revolutionized the pharmacological treatment of obesity.New molecules will soon be marketed that will expand the treatment possibilities, which will also be reviewed in this article.…”
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  15. 4215

    Association of killer immunoglobulin-like receptor genotypes and haplotypes with acute lymphoblastic leukemia risk by Jameel Al-Tamimi, Suliman Alomar, Ali Aljuaimlani, Lamjed Mansour

    Published 2025-01-01
    “…Background Killer immunoglobulin-like receptors (KIRs) are key molecules used by natural killer (NK) cells to interact with target cells. …”
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  16. 4216

    Study on the Correlation between Interleukin-27 and CXCL10 in Pulmonary Tuberculosis by Jiahui Fan, Yefeng Yang, Liang Wang, Xiaoqian Shang, Li Zhang, Hu Sun, Yujie Ma, Ying Li, Jing Wang, Xiumin Ma

    Published 2022-01-01
    “…Both immunohistochemical staining and qRT-PCR indicated that the expressions of IL-27, CXCL9, CXCL10, and CXCL11 were significantly increased in tuberculosis patients, and IL-27 was significantly correlated with CXCL10 (r=0.68). Key molecules such as has-let-7b-5p, has-miR-30a-3p, and has-miR-320b were screened out. …”
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  17. 4217

    The Role of Dll4/Notch Signaling in Normal and Pathological Ocular Angiogenesis: Dll4 Controls Blood Vessel Sprouting and Vessel Remodeling in Normal and Pathological Conditions by Ivan Lobov, Natalia Mikhailova

    Published 2018-01-01
    “…Several genetic approaches and therapeutic molecules were tested to evaluate the biological and therapeutic effects of acute and prolonged Dll4 inhibition in the eye and oncology. …”
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  18. 4218

    DETECTION OF CAMPYLOBACTER SPP. WITH REAL-TIME POLYMERASE CHAIN REACTION by G. S. Skitovich, K. V. Serova, N. B. Shadrova, O. V. Pruntova

    Published 2019-12-01
    “…The method sensitivity was 40 target molecules. The said method was used for testing 76 samples of raw materials of animal origin. …”
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  19. 4219

    Exerkines and Sarcopenia: Unveiling the Mechanism Behind Exercise-Induced Mitochondrial Homeostasis by Jiayin Wang, Dandan Jia, Zhiwang Zhang, Dan Wang

    Published 2025-01-01
    “…., adipokines, myokines, hepatokines, and osteokines), signaling molecules released in response to exercise training, may potentially contribute to skeletal muscle metabolism through ameliorating mitochondrial homeostasis, reducing inflammation, and regulating protein synthesis as a defense against sarcopenia. …”
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  20. 4220

    Investigation and Identification of let-7a Related Functional Proteins in Gastric Carcinoma by Proteomics by Yimin Zhu, Xingyuan Xiao, Lairong Dong, Zhiming Liu

    Published 2012-01-01
    “…MicroRNAs are small noncoding RNA molecules that control expression of target genes. …”
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