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- Physics 1
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4141
The bile acid chenodeoxycholic acid associates with reduced stroke in humans and mice
Published 2025-01-01“…Bile acids are liver-derived signaling molecules that can be found in the brain, but their role there remains largely unknown. …”
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4142
Molecular Mechanisms Underlying Neuroinflammation Intervention with Medicinal Plants: A Critical and Narrative Review of the Current Literature
Published 2025-01-01“…Neuroinflammation is a key factor in the progression of neurodegenerative diseases, driven by the dysregulation of molecular pathways and activation of the brain’s immune system, resulting in the release of pro-inflammatory and oxidative molecules. This chronic inflammation is exacerbated by peripheral leukocyte infiltration into the central nervous system. …”
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4143
Development of a Duplex PCR-NALFIA Assay for the Simultaneous Detection of <i>Macrophomina phaseolina</i> and <i>Verticillium dahliae</i> Causal Agents of Crown and Root Rot of Str...
Published 2025-01-01“…In this work, we developed a duplex PCR-NALFIA assay using two pairs of species-specific primers labeled at the 5′ end with different molecules for the simultaneous identification of <i>Mp</i> and <i>Vd</i>. …”
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4144
Development and Characterisation of a Novel NF-κB Reporter Cell Line for Investigation of Neuroinflammation
Published 2017-01-01“…Thus, we developed a stable neural NF-κB-reporter cell line to assess the potency of proinflammatory molecules and peptides, as well as anti-inflammatory pharmaceuticals. …”
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4145
The plastid and mitochondrial genomes of <i>Vavilovia Formosa</i> (Stev.) Fed. and the phylogeny of related legume genera
Published 2020-01-01“…The organellar genomes were circular DNA molecules; the genome of mitochondria was represented by two circular chromosomes. …”
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4146
Effects of Quorum Sensing Systems on Regulatory T Cells in Catheter-Related Pseudomonas aeruginosa Biofilm Infection Rat Models
Published 2016-01-01“…Recent studies have found that the QS molecules had complex effects on the host immune systems. …”
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4147
TREM-2 Receptor Expression Increases with 25(OH)D Vitamin Serum Levels in Patients with Pulmonary Sarcoidosis
Published 2015-01-01“…TREM-1 and TREM-2 molecules are members of the TREM transmembrane glycoproteins. …”
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4148
Molecular Signatures of Humic Acids from Different Sources as Revealed by Ultrahigh Resolution Mass Spectrometry
Published 2020-01-01“…Regardless of unsaturation, molecules of River HA have a homogeneous molecular mass distribution and contain many plant-derived lignin- and tannin-like compounds, which are more stable than lipid and more labile than condensed aromatics. …”
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4149
Adsorption of Mo and O at S-vacancy on ReS2 surface of ReS2/MoTe2 vdW heterointerface
Published 2025-06-01“…Therefore, determining the role of defect-induced states and the adsorption of atoms/molecules on surfaces is crucial. Moreover, a detailed theoretical study to determine surface properties and relative energetic stability of the vdW heterostructures is carried out. …”
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4150
Combinations of TLR Ligands: A Promising Approach in Cancer Immunotherapy
Published 2013-01-01“…Toll-like receptors (TLRs), a family of pattern recognition receptors recognizing molecules expressed by pathogens, are typically expressed by immune cells. …”
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4151
Activatable Sulfur Dioxide Nanosonosensitizer Enables Precisely Controllable Sono‐Gaseous Checkpoint Trimodal Therapy for Orthotopic Hepatocellular Carcinoma
Published 2025-02-01“…This “activatable SO2 nanosonosensitizer,” Aza‐DNBS nanoparticles (NPs), are established by self‐assembling Aza‐boron‐dipyrromethene based sonosensitizer molecules and 2,4‐dinitrobenzenesulfonate (DNBS)‐caged SO2 prodrug. …”
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4152
FFAR4 (GPR120) Signaling Is Not Required for Anti-Inflammatory and Insulin-Sensitizing Effects of Omega-3 Fatty Acids
Published 2016-01-01“…Moreover, ω3-PUFA fed mice had increased circulating protein levels of the anti-inflammatory adipokine, adiponectin, decreased fasting insulin levels, and decreased mRNA expression of several proinflammatory molecules within visceral adipose tissue. In conclusion, we find that FFAR4 signaling is not required for the reported anti-inflammatory and insulin-sensitizing effects mediated by ω3-PUFAs.…”
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4153
Highly corrosion-resistant and photocatalytic hybrid coating on AZ31 Mg alloy via plasma electrolytic oxidation with organic-inorganic integration
Published 2025-01-01“…Potassium hydroxide (KOH) was used to adjust the pH, improving the interaction and solubility between the organic molecules and the PEO coating. The hybrid coating exhibited unique twig-like surface structures that contributed to forming a multifunctional coating with high corrosion resistance and superior photocatalytic activity. …”
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4154
Deletion of IRS-1 leads to growth failure and insulin resistance with downregulation of liver and muscle insulin signaling in rats
Published 2025-01-01“…Abstract Insulin receptor substrate (IRS)-1 and IRS-2 are major molecules that transduce signals from insulin and insulin-like growth factor-I receptors. …”
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4155
Molecular Structure and Electronic Properties of Porphyrin-Thiophene-Perylene Using Quantum Chemical Calculation
Published 2010-01-01“…The structural and electronic properties of the molecules, and the effects of mono- and di-substituents R on C3 and R′ on C4 of the thiophene ring were investigated using a quantum calculation approach. …”
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4156
Polysulfur-based bulking of dynamin-related protein 1 prevents ischemic sulfide catabolism and heart failure in mice
Published 2025-01-01“…Abstract The presence of redox-active molecules containing catenated sulfur atoms (supersulfides) in living organisms has led to a review of the concepts of redox biology and its translational strategy. …”
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4157
Experimental study on the drag reduction performance of sodium alginate in saline solutions
Published 2024-12-01“…However, during the initial stage of turbulence, a small amount of salt facilitates the unfolding of sodium alginate molecules, thereby enhancing the drag reduction effect (ε > 100%). …”
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4158
The solvent effect, preferential solvation of metformin hydrochloride in binary mixed solvents of methanol/ethanol + water mixtures from 278.15 K to 323.15 K
Published 2025-04-01“…This enhanced solvation by water may be attributed to the disordered structure of the alcohol molecules surrounding the polar regions of MET-HCl. …”
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4159
Laboratory Measurement of CH317OH Transitions in the Frequency Range from 216 to 264 GHz for Astronomical Application
Published 2025-01-01“…Methanol is one of the most abundant complex organic molecules in interstellar environments. Molecular lines of its rare isotopologues ^12 CH _3 ^17 OH and ^12 CH _3 ^18 OH therefore play a crucial role in examining the column density of ^12 CH _3 ^16 OH, which serves as a reference for organic molecular chemistry in interstellar clouds. …”
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4160
COVID‐19 in early 2023: Structure, replication mechanism, variants of SARS‐CoV‐2, diagnostic tests, and vaccine & drug development studies
Published 2023-04-01“…Drug studies, therapeutic targets, various immunomodulators, and antiviral molecules applied to patients with COVID‐19 have been reviewed.…”
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