Biomarkers in Nasopharyngeal Carcinoma (NPC): Clinical relevance and prognostic potential by Madhan Krishnan, Shyamaladevi Babu

“…However, ongoing research has identified additional biomarkers, such as circulating tumor cells (CTCs), microRNAs, and immune-related molecules that provide further prognostic insights. …”
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Polysaccharide-based biomaterials for regenerative therapy in intervertebral disc degeneration by Xin Wang, Yixue Huang, Yilin Yang, Xin Tian, Yesheng Jin, Weimin Jiang, Hanliang He, Yong Xu, Yijie Liu

“…Furthermore, polysaccharide-based hydrogels have demonstrated the potential to deliver bioactive molecules, including growth factors, cytokines and anti-inflammatory drugs, directly to the degenerated disc environment, thereby enhancing therapeutic outcomes. …”
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Exploring corrosion protection of mild steel by ionic liquid functionalized graphene oxide: Gravimetric, electrochemical, and surface studies by M.Alharbi, Ruby Aslam, Ajahar Khan, Khalid A. Alamry, Mahmoud A. Hussein, Yas Al-Hadeethi, Elena Bekyarova, S. Alqahtani

“…The pronounced increases in polarization resistance (Rp) and reductions in corrosion current density (Icorr) indicated the strong adsorption of inhibitor molecules onto metal surface. In addition, the values of open circuit potential (OCP) and corrosion potential (Ecorr) were further evidence of a mixed inhibition mechanism. …”
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Role of Cox-2 in Vascular Inflammation: An Experimental Model of Metabolic Syndrome by Nicolás F. Renna, Emiliano R. Diez, Carina Lembo, Roberto M. Miatello

“…FFHR presented all variables of metabolic syndrome; there was also an increase in oxidative stress variables; vascular remodeling and left ventricular hypertrophy were evidenced along with a significant increase in the expression of the mentioned proinflammatory molecules and increased activity and expression of collagenase. …”
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Serum Oxidative Stress-related Biomarkers in Ocular Hypertension and Glaucoma by Mine Esen Baris, Onur Furundaoturan, Meltem Kocamanoğlu, Seray Sahin, Yasemin Akçay, Suzan Güven Yılmaz

“… Purpose: To evaluate the serum levels of oxidative stress-related molecules in patients with ocular hypertension (OHT) and primary open-angle glaucoma (POAG) compared with healthy controls. …”
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Cross-sectional study of proteomic differences between moderate and severe psoriasis by Lingling Wu, Chen Cen, Bibo Xie, Lihua Hu, Jia Huang, Ningning Shen, Qiang Dong

“…Our data identify Eighteen DEPs as biomarkers of disease severity, and are associated with IL − 17 signalling pathway, Neutrophil extracellular trap formation, NF − kappa B signalling pathway, and defence response to the bacterium. Targeting these molecules and measures to manage infection may improve psoriasis’s severity and therapeutic efficacy.…”
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Post-traumatic arthritis: overview on pathogenic mechanisms and role of inflammation by Roberta Ramonda, Leonardo Punzi, Anna Scanu, Francesca Oliviero, Roberto Luisetto, Paola Galozzi, Marta Favero

“…Human studies and experimental models have revealed that a series of inflammatory mediators are released in synovial fluid immediately after the joint trauma. These molecules have been proposed as markers of disease and as a potential target for the development of specific and preventative interventions. …”
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Semiclassical Estimates of Pressure-induced Line Widths for Infrared Absorption in Hot (Exo)planetary Atmospheres by Jeanna Buldyreva, Kathleen Stehlin, Sergei N. Yurchenko, Elizabeth R. Guest, Jonathan Tennyson

“…Because of elevated temperatures and high fluxes of stellar radiation irreproducible in laboratory conditions, molecules and molecular ions found or expected in exoplanetary atmospheres are generally poorly characterized from the viewpoint of their spectroscopic line-shape parameters; in many cases, there are no data at all. …”
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Mathematical Modelling of Acetaminophen Release in HPC/PAAm Hydrogel: Synthesis and Application by Abigail M. Díaz-Guerrero, Claudia A. Castillo-Miranda, Carlos F. Castro-Guerrero, Hernán Peraza-Vázquez, Ana B. Morales-Cepeda, Adrián F. Peña-Delgado

“…Hydrogels are commonly used as Drug Delivery Systems (DDS) as patches due to its ability to store drug molecules within their structures. The release can be activated under certain stimuli, such as temperature and pH. …”
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Electroacupuncture Improved Hippocampal Neurogenesis following Traumatic Brain Injury in Mice through Inhibition of TLR4 Signaling Pathway by Yuqin Ye, Yongxiang Yang, Chen Chen, Ze Li, Yanfeng Jia, Xinhong Su, Chaoxian Wang, Xiaosheng He

“…The hippocampal level of TLR4 and downstream molecules and inflammatory cytokines were, respectively, detected by Western blot and enzyme-linked immunosorbent assay. …”
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Nano-MIP based SPR sensor for tetracycline analysis in milk sample by Monireh Bakhshpour-Yücel, Melike Küçük, Elif Tümay Özer, Bilgen Osman

“…The relationship between Tc molecules and the SPR sensor was analyzed at 0.5–20 mg/L Tc concentrations (pH 5.0). …”
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LEGO-Lipophosphonoxin membrane activity is enhanced by presence of phosphatidylethanolamine but hindered by outer membrane by Hana Brzobohatá, Milica Dugić, Viktor Mojr, Nitjawan Sahatsapan, Ivana Kóšiová, Tomáš Křížek, Tereza Dolejšová, Petra Lišková, Lukasz Cwiklik, Dominik Rejman, Radovan Fišer, Gabriela Mikušová

“…The proposed mechanism stems from an electrostatic repulsion between highly positively charged LEGO-1 molecules and positively charged amino groups of phosphatidylethanolamine which destabilizes the membrane. …”
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Extracellular Cold-Inducible RNA-Binding Protein and Hemorrhagic Shock: Mechanisms and Therapeutics by Naureen Rashid, Zhijian Hu, Asha Jacob, Ping Wang

“…Hypoxia and hypoperfusion lead to the release of molecules that act as danger signals known as damage-associated molecular patterns (DAMPs). …”
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Effect of miR-223-3p and miR-328a-3p Knockdown on Allergic Airway Inflammation in Rat Precision-Cut Lung Slices by Joanna Nowakowska, Maria Kachel, Wojciech Langwiński, Kamil Ziarniak, Aleksandra Szczepankiewicz

“…One of the asthma research models is precision-cut lung slices (PCLSs), and among the therapeutic options, miRNA molecules are of great interest. The aim of our study was to investigate whether inhibition of miR-223-3p and miR328a-3p affects the inflammatory response in PCLSs derived from a rat with HDM-induced allergic inflammation and a control rat. …”
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Targeting the CLK2/SRSF9 splicing axis in prostate cancer leads to decreased ARV7 expression by Jasper Van Goubergen, Miroslav Peřina, Florian Handle, Elisa Morales, Anika Kremer, Oliver Schmidt, Glen Kristiansen, Marcus V. Cronauer, Frédéric R. Santer

“…Inhibition of the Cdc2‐like kinase (CLK) family by the small molecules cirtuvivint or lorecivivint results in the decreased expression of ARV7. …”
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Low-Intensity Pulsed Ultrasound Modulates RhoA/ROCK Signaling of Rat Mandibular Bone Marrow Mesenchymal Stem Cells to Rescue Their Damaged Cytoskeletal Organization and Cell Biolog... by Rong Zhang, Zhaoling Wang, Guoxiong Zhu, Gaoyi Wu, Qingyuan Guo, Hongchen Liu, Lei Chen

“…More importantly, it could reverse the aberrant expression of the key molecules induced by radiation. Inhibition of RhoA/ROCK signaling remarkably aggravated the inhibitory effect of radiation and attenuated the therapeutic effect of LIPUS. …”
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Synthesis and characterization of citrate-capped gold nanoparticles and their application in selective detection of creatinine (A kidney biomarker) by Akriti Tirkey, Punuri Jayasekhar Babu

“…The principle of this method is based on the aggregation of C-AuNPs induced by the creatinine molecules which has been successfully employed for the colorimetric detection of creatinine ranging from 0.3 to 0.8 μg/100 μl (3–8 ppm). …”
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Expression Profiling Using a cDNA Array and Immunohistochemistry for the Extracellular Matrix Genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in Colorectal Carcinoma Progression and D... by Suzana Angelica Silva Lustosa, Luciano de Souza Viana, Renato José Affonso, Sandra Regina Morini Silva, Marcos Vinicius Araujo Denadai, Silvia Regina Caminada de Toledo, Indhira Dias Oliveira, Delcio Matos

“…The expression associations between ECM molecules and selected epithelial markers EGFR, VEGF, Bcl2, P53, and KI-67 have also been examined in 114 patients with colorectal cancer who underwent primary tumor resection. …”
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Effect of Pea Resistant Starch on Emulsion Gel Properties and in Vitro Digestibility of Myofibrillar Proteins by CHEN Jinyu, HU Fangyang, JI Zhirui, WU Zijian

“…The chemical force results showed that the addition of pea RS3 led to enhanced hydrophobic interaction and disulfide bonding between MP molecules. Low field-nuclear magnetic resonance (LF-NMR) confirmed that pea RS3 addition facilitated the migration of free water to immobilized water. …”
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One-pot green synthesis of BSA-capped O-CQDs as an effective fluorescent sensing platform for sensitive and selective detection of promethazine drug by S. Viji, A. Dinesh, K. Radhakrishnan, L. Srimathi Priya, C. Sivasankari, Madhappan Santhamoorthy, Manikandan Ayyar, V. Mohanavel, Mohamed Hashem, Hassan Fouad, G. Ramachandran, S. Santhoshkumar

“…Reliability in biosensing technologies is crucial for the accurate detection and measurement of target molecules, prompting strategies to minimise non-specific binding events that may result in inaccurate findings. …”
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