Characterization and evaluation of the cytotoxic, antioxidant, and anti-human lung cancer properties of copper nanoparticles green-synthesized by fennel extract following the PI3K/... by Tao Huang, KaiLi Ma, Yihua Wang

“…There was plenty of evidence that CuNPs had anti-cancer potential; this has been shown by the effect of the molecules on the PI3K/AKT/mTOR pathway, which was one of the pathways crucial for cancer survival. …”
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Hsa_circ_0000190 Promotes NSCLC Cell Resistance to Cisplatin via the Modulation of the miR-1253/IL-6 Axis by Hua He, Tian Li

“…Interactions between different RNA molecules were assessed using both RNA immunoprecipitation and dual-luciferase reporter assays. …”
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Thiophene-fused aromatic belts by Hiroki Shudo, Philipp Wiesener, Elena Kolodzeiski, Kiichi Mizukami, Daiki Imoto, Harry Mönig, Saeed Amirjalayer, Hirotoshi Sakamoto, Henning Klaasen, Bart Jan Ravoo, Nobuo Kimizuka, Akiko Yagi, Kenichiro Itami

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Identification and Characterization of a Novel Rat MAVS Variant Modulating NFκB Signaling by Ihsan Nalkiran, Hatice Sevim Nalkiran

“…The seven-amino-acid deletion in MAVS500 induces significant conformational rearrangements, reducing helical turns and altering structural dynamics, which may impact its interactions with downstream signaling molecules in the innate immune pathway. The identification of MAVS500 enhances our understanding of MAVS regulation and its role in the innate immune response, providing valuable insights into alternative splicing as a mechanism for diversifying protein function.…”
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Complexation with pre-formed “empty” V-type starch for encapsulation of aroma compounds by Jingyi Zhou, Lingyan Kong

“…Aroma compounds are low-molecular-weight organic volatile molecules and are broadly utilized in the food industry. …”
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Construction of a Multicellular Communication Network Model for Cell Co-Culture Technology and Evaluation of Its Simulation Capability by Yuan-Yuan Geng, Chao Wei, Guo-Fei Chen, Bai-Xia Zhang

“…Through the correspondence and location information of signal molecules and receptors, type-specific networks of single cells were connected and a multicellular network of smooth muscle cells, neurons, and vascular endothelial cells was constructed. …”
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The Effect of Geometrical Shape of Surface Texture on the Rheology and Tribology of Confined Lubricants by Fankai Peng, Ahmad Jabbarzadeh

“…The squaretooth patterns exhibit the lowest viscosities due to the nematic order in crystalline bridges with molecules aligned in the shearing direction. The sinusoidal wave-patterned surface shows intermediary viscosity with disordered crystalline bridge groups formed with random molecular orientation. …”
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Advancements in single-cell RNA sequencing and spatial transcriptomics: transforming biomedical research by Getnet Molla Desta, Getnet Molla Desta, Alemayehu Godana Birhanu

“…Spatial transcriptomics is a pivotal advancement in medical biotechnology, facilitating the identification of molecules such as RNA in their original spatial context within tissue sections at the single-cell level. …”
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Correlation of Vitamin B12 Levels with Clinical and Laboratory Features in Patients of Dengue Fever by Asma Abdul Razzak

“…The creation of DNA, the genetic information-carrying molecules found inside cells, as well as the metabolism of cells, neuron function, and red blood cell development all depend on vitamin B-12.6 Measurements of serum or plasma vitamin B12 levels are commonly used to determine vitamin B12 status. …”
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Separation of Some Anionic Dyes Using Reverse Micelles of CTAB and SDS as Efficient Surfactants Adsorbents from Aqueous Medium by Heba M. El Refay, Nagwa Badawy, Amina Hamada, El Shimaa Hassen

“…Recovery of the solvent and the reuse of dyes and surfactants after extraction of dye molecules from reverse micelles surfactant core considered are very important from an economic point of view. …”
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MicroRNAs in atrial fibrillation – have we discovered the Holy Grail or opened a Pandora’s box? by Alkora Ioana Balan, Alina Scridon

“…A Pandora’s box might thus have opened with the advent of these sophisticated molecules. In this paper, we provide a critical analysis of the clinical and experimental, epidemiological and mechanistic data linking miRNAs to AF, we discuss the most promising miRNA therapeutic approaches, we emphasize a number of questions that remain to be answered, and we identify hotspots for future research.…”
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Circular RNAs as a novel class of potential therapeutic and diagnostic biomarkers in reproductive biology/diseases by Wanyu Song, Xiuli Chen, Haiying Wu, Neda Rahimian

“…Due to the progress made in high-speed gene sequencing, a large amount of circRNA molecules have been detected, revealing their significant functions in diverse biological functions like enhancing testicular development, preserving the differentiation and renewal of spermatogonial cells, and controlling spermatocyte meiosis. …”
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Influence of the Branched Structure of Polyoxyethylene Units in Nonionic Surfactants on the Wettability of Anthracite: A Combined Modeling and Experimental Study by Xuanlai Chen, Guochao Yan, Guang Xu, Xianglin Yang, Jiajun Li, Xuyang Bai

“…The network structure formed by C12(EO)20 is denser. Water molecules have a higher aggregation degree near Tween 20 and stronger permeability, and more hydrogen bonds are formed. …”
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Bundle sheath cell-dependent chloroplast movement in mesophyll cells of C4 plants analyzed using live leaf-section imaging by Yuta Kato, Takao Oi, Yoshikatsu Sato, Mitsutaka Taniguchi

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Epithelial to Mesenchymal Transition Relevant Subtypes with Distinct Prognosis and Responses to Chemo- or Immunotherapies in Osteosarcoma by Yang Zhou, Gai Li, Hu Li, Fuchong Lai, Pingguo Duan, Ming Cheng

“…Our goal was to classify osteosarcoma patients into clinical/biological subtypes based on EMT molecules. Methods. This study retrospectively curated the RNA expression profiling of osteosarcoma patients from the TARGET and GSE21257 cohorts. …”
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Self-Centered Function of Adaptive Immunity in Regulation of Immune Responses and in Tolerance by Silvana Balzar

“…., the context of MHC molecules. Therefore, not only repertoire selection and maintenance but also the T/B cell activation and function are self-centered. …”
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Superconductivity of electron-doped chalcohydrides under high pressure by Yu Du, Zefang Wang, Hanyu Liu, Guoji Liu, Xin Zhong

“…Notably, metallic LiSH_{7} and Li_{2}SH_{6} exhibit a layered structure where the covalent bond between sulfur and hydrogen breaks up and the hydrogen atoms are released to recombine into molecules confined into the interlayer. Furthermore, our electron-phonon simulations reveal that the estimated superconducting transition temperature (T_{c}) of Li_{2}SH_{6} (46 K) is lower than that (77 K) of Li_{2}SeH_{6} at 200 GPa, which contrasts with the general belief that the light-weight elemental compound (high Debye temperature) has higher superconductivity. …”
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Bile acids regulation of cellular stress responses in liver physiology and diseases by Tiangang Li, Mohammad Nazmul Hasan, Lijie Gu

“…Bile acids are physiological detergents and signalling molecules that are critically implicated in liver health and diseases. …”
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Astragaloside IV Inhibits NF-κB Activation and Inflammatory Gene Expression in LPS-Treated Mice by Wei-Jian Zhang, Balz Frei

“…Lung mRNA levels of cellular adhesion molecules, MCP-1, TNFα, IL-6, and TLR4 were significantly attenuated, and lung neutrophil infiltration and activation were strongly inhibited, as reflected by decreased myeloperoxidase content, when the mice were pretreated with AS-IV. …”
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AI-driven prediction of drug activity against Toxoplasma gondii: Data augmentation and deep neural networks for limited datasets by Natalia V. Karimova, Ravithree D. Senanayake

“…Finally, the model was applied to screen FDA-approved drugs after filtering out molecules that did not align with the characteristics of the training dataset. …”
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