Suggested Topics within your search.
Suggested Topics within your search.
- Physics 1
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3961
Memristors Based on Ni(II)‐tetraaza[14]annulene Complexes: Toward an Unconventional Resistive Switching Mechanism
Published 2024-12-01“…Finding a unique case of filamentary‐type resistive switching involving redox reactions of stationary molecules within a molecular solid is postulated. Yet, the formation of these filaments is not related to any significant configurational changes at the atomic scale.…”
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3962
The Involvement of Notch1-RBP-Jk/Msx2 Signaling Pathway in Aortic Calcification of Diabetic Nephropathy Rats
Published 2017-01-01“…VSMC markers and osteogenic markers as well as target molecules in Notch1-RBP-Jk/Msx2 were determined by quantitative real-time polymerase chain reaction and immunohistochemical analysis. …”
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3963
New semisynthetic α-glucosidase inhibitor from a doubly-chemically engineered extract
Published 2025-01-01“…Abstract Chemically engineered extracts represent a promising source of new bioactive semi-synthetic molecules. Prepared through direct derivatization of natural extracts, they can include constituents enriched with elements and sub-structures that are less common in natural products compared to drugs. …”
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3964
The Influence of Air Flow Rates and Voltage on the Plasma Emission Spectra and the Concentrations of Nitrogen Oxides Produced by Gliding Arc Discharge Plasma
Published 2025-01-01“…It was observed that the reduction in the discharge frequency increased the intensity of the excited nitrogen molecules lines and reduced the nitric oxide (NO) and nitrogen dioxide (NO<sub>2</sub>) gas concentrations. …”
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3965
Extracecellulr vesicles (EVs) microRNAs (miRNAs) derived from mesenchymal stem cells (MSCs) in osteoarthritis (OA); detailed role in pathogenesis and possible therapeutics
Published 2025-02-01“…Further, attractive candidates for cell-free therapy for OA are MSC-derived extracecellulr vesicles (EVs) that convey bioactive molecules of the original cells, such as microRNAs. …”
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3966
Antioxidant Capacity and Radical Scavenging Effect of Polyphenol Rich Mallotus philippenensis Fruit Extract on Human Erythrocytes: An In Vitro Study
Published 2014-01-01“…Mallotus philippinensis is an important source of molecules with strong antioxidant activity widely used medicinal plant. …”
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3967
Mesenchymal stem cells and their extracellular vesicle therapy for neurological disorders: traumatic brain injury and beyond
Published 2025-02-01“…Studies indicate that MSCs can promote neurogenesis and angiogenesis through various mechanisms, including releasing bioactive molecules and extracellular vesicles (EVs), which help reduce neuroinflammation. …”
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3968
Molecular-genetic mechanisms underlying fruit and seed coloration in plants
Published 2015-12-01“…The genes encoding enzymes involved in step-bystep conversion of initial organic molecules to final pigmented compounds are referred to as structural genes, while regulatory genes are responsible for activation of the expression of structural genes and control the synthesis of pigments at certain times and in proper tissue. …”
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3969
Effects of Maillard reaction and its product AGEs on aging and age-related diseases
Published 2024-05-01“…Despite certain advantages based on Maillard reaction products (MRPs) found in some food for health and storage application have appeared, however, the MR occurring in human physiological environment can produce advanced glycation end products (AGEs) by non-enzymatic modif ication of macromolecules such as proteins, lipids and nucleic acid, which could change the structure and functional activity of the molecules themselves. In this review, we take AGEs as our main object, on the one hand, discuss physiologic aging, that is, age-dependent covalent cross-linking and modif ication of proteins such as collagen that occur in eyes and skin containing connective tissue. …”
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3970
Ruthenium(II) Lipid‐Mimics Drive Lipid Phase Separation to Arouse Autophagy‐Ferroptosis Cascade for Photoimmunotherapy
Published 2025-01-01“…This study presents an unprecedented discovery of small molecules capable of inducing and monitoring lipid phase separation, thereby eliciting robust immune responses in living cells. …”
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3971
Lipidomic Signature of Pregnant and Postpartum Females by Longitudinal and Transversal Evaluation: Putative Biomarkers Determined by UHPLC-QTOF-ESI<sup>+</sup>-MS
Published 2025-01-01“…Our results revealed significant metabolic differences between pregnant and postpartum women, with lipid molecules such as estrogen derivatives, fatty acids, and ceramides showing strong potential as biomarkers. …”
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3972
Tissue- and Cell Type-Specific Expression of the Long Noncoding RNA Klhl14-AS in Mouse
Published 2017-01-01“…The extreme heterogeneity in the mechanisms of action of these molecules, however, makes them very difficult to study, especially regarding their molecular function. …”
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3973
BMP4 Cooperates with Retinoic Acid to Induce the Expression of Differentiation Markers in Cultured Mouse Spermatogonia
Published 2016-01-01“…Spermatogenesis is sustained by the proliferation and differentiation of spermatogonial stem cells (SSCs). However, the molecules controlling these processes remain largely unknown. …”
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3974
Spectroscopic aspects of underwater digital holography of plankton
Published 2025-01-01“…By constructing the analogies based on the spectroscopy of atoms and molecules the paper shows the bioindication capabilities of the Fourier spectra of the plankton ecosystem function, built during monitoring measurements using a submersible digital holographic camera. …”
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3975
Hydrothermal Synthesis of Modified Hydrophobic Zn–Al-Layered Double Hydroxides Using Structure-Directing Agents and Their Enhanced Adsorption Capacity for -Nitrophenol
Published 2014-05-01“…A possible formation mechanism of the special three-dimensional nanostructures from the primary LDH nanosheet building units is proposed on the basis of the interaction between SS molecules and LDH crystals. The size of the channel height is approximately equal to the diameter of the intercalated anion SDBS, indicating that SDBS is in a vertical single-layer arrangement. using p -nitrophenol as model pollutant, the effects of initial concentration of p -nitrophenol and contact time on the adsorption of p -nitrophenol using various ZnAl–LDHs were investigated by performing a series of experiments. …”
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3976
Impact of Peritoneal Dialysis Treatment on Arterial Stiffness and Vascular Changes in Diabetic Type 2 and Nondiabetic Patients with End-Stage Renal Disease
Published 2013-01-01“…PD treatment, with the regulation of these vasoactive molecules and other vascular risk factors, significantly contributes to vascular remodeling, especially in DM patients.…”
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3977
The Synthesis Followed by Spectral and Calorimetric Evaluation of Stability of Human Milk Fat Substitutes Obtained from Thistle Milk and Lard
Published 2019-01-01“…Although PDSC curves showed lower oxidative stability of newly synthesized fats as compared to both starting materials separately, they can be considered adequate substitutes of human fat milk fat, as distribution of fatty acids in triacylglycerol molecules of substitutes obtained is much alike human milk fat itself, as resulted from analysis of GC data collected. …”
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3978
First two mitochondrial genomes for the order Filobasidiales reveal novel gene rearrangements and intron dynamics of Tremellomycetes
Published 2022-05-01“…The mitogenomes of F. wieringae and F. globisporum both comprised circular DNA molecules, with sizes of 27,861 bp and 71,783 bp, respectively. …”
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3979
Lipid metabolic remodeling delays senescence of T cells to potentiate their immunity against solid tumors
Published 2025-01-01“…Systemic administration of surface-engineered T cells resulted in superior infiltration in solid tumors and improved antitumor efficacy by enhancing the secretion of cytotoxic molecules, thereby prolonging the survival of mice bearing colorectal carcinoma and melanoma xenografts.Conclusions Lipid-metabolically remodeled T cells with delayed senescence increase efficacy in tumor microenvironment, highlighting a novel strategy for solid tumor immunotherapy.…”
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3980
Deregulation mechanisms and therapeutic opportunities of p53-responsive microRNAs in diffuse large B-cell lymphoma
Published 2025-01-01“…The starting point is a brief description of the classical microRNA biogenesis pathway and the role of p53 in regulating the expression of these molecules. We analyze various molecular mechanisms leading to this dysregulation, including mutations in the TP53 gene, DNA methylation, changes in host-genes expression or microRNA gene copy number, mutations in microRNA and microRNA biogenesis genes.…”
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