MiRNA target enrichment analysis of co-expression network modules reveals important miRNAs and their roles in breast cancer progression by Bazyari Mohammad Javad, Aghaee-Bakhtiari Seyed Hamid

“…MicroRNAs are small RNA molecules that have pivotal roles in the regulation of gene expression and they control different properties in breast cancer such as progression. …”
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ER Stress and Iron Homeostasis: A New Frontier for the UPR by Susana J. Oliveira, Maria de Sousa, Jorge P. Pinto

“…Also due to the faulty assembly with β2m, HFE-C282Y molecules remain in the endoplasmic reticulum (ER) as aggregates that undergo proteasomal degradation and activate an Unfolded Protein Response (UPR). …”
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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM. by Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman

“…Herein, we developed biochemical and biophysical assays to enable the discovery of small molecules that perturb the interaction between the FCER1G p-ITAM and SYK-tSH2. …”
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Mycovirome of Diaporthe helianthi and D. gulyae, causal agents of Phomopsis stem canker of sunflower (Helianthus annuus L.) by Chien-Fu Wu, Elizabeth Regedanz, Febina Mathew, Ruchika Kashyap, Karthika Mohan, Shin-Yi Lee Marzano

“…Besides an understanding of virome diversity, the mycovirome survey provides the first clue of biological molecules that can be further developed for antifungal purposes.…”
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Alzheimer’s disease and infectious agents: a comprehensive review of pathogenic mechanisms and microRNA roles by Seyyed Sam Mehdi Hosseininasab, Rasoul Ebrahimi, Shirin Yaghoobpoor, Kiarash Kazemi, Yaser Khakpour, Ramtin Hajibeygi, Ashraf Mohamadkhani, Mobina Fathi, Kimia Vakili, Arian Tavasol, Zohreh Tutunchian, Tara Fazel, Mohammad Fathi, Mohammadreza Hajiesmaeili

“…In addition, microRNAs (miRNAs) might play a crucial role in the pathogenesis mechanisms of these pathogens since they are utilized to target various protein-coding genes, allowing for immune evasion, maintaining latency, and suppressing cellular signaling molecules. Also, they can regulate gene expression in human cells. …”
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An integrated method for taxonomic identif ication of microorganisms by Yu. E. Uvarova, A. V. Bryanskaya, A. S. Rozanov, V. N. Shlyakhtun, E. A. Demidov, K. V. Starostin, T. N. Goryachkovskaya, S. V. Shekhovtsov, N. M. Slynko, S. E. Peltek

“…For accurate species-level identification of microorganisms, researchers today increasingly use a combination of standard microbiological cultivation and visual observation methods with molecular biological and genetic techniques that help distinguish between species and strains of microorganisms at the level of DNA or RNA molecules. The aim of this work was to identify microorganisms from the ICG SB RAS Collection using an integrated approach that involves a combination of various phenotypic and genotypic characteristics. …”
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Comprehensive analysis of differential mRNA and circRNA profiles in primary and metastatic pancreatic neuroendocrine tumors by Gang Li, Jing Zhang, Bentuo Zhang, Dan Wang, Zequn Wang, Yan Pan, Lijie Ma

“…Understanding the characteristics of these tumors, particularly the key molecules involved in metastasis, is essential. To address this, we utilized mRNA expression data from human pNET and metastatic pancreatic tumor tissues available in the GEO database and integrated this data with bioinformatics analyses. …”
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Adipocytokine Associations with Insulin Resistance in British South Asians by D. R. Webb, K. Khunti, S. Chatterjee, J. Jarvis, M. J. Davies

“…We investigated adiponectin, leptin, and TNF-α and assessed the contribution of these molecules to insulin resistance in south Asians. Hypothesis. …”
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Electrochromism via reversible electrodeposition of solid iodine by Shanlin Li, Yingyu Chen, Zhen Wang, Mengmeng Wang, Xianglin Guo, Xueqing Tang, Xiaoyu Wang, Wende Lai, Meiyun Tong, Changhong Wang, Shan Cong, Fengxia Geng, Yong Chen, Zhigang Zhao

“…Since then, researchers have identified various electrochromic material systems, including transition metal oxides, polymer materials, and small molecules. However, the electrochromic phenomenon has rarely been observed in non-metallic elemental substances. …”
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Renal and Hematological Effects of CLCF-1, a B-Cell-Stimulating Cytokine of the IL-6 Family by Virginia J. Savin, Mukut Sharma, Jianping Zhou, David Gennochi, Timothy Fields, Ram Sharma, Ellen T. McCarthy, Tarak Srivastava, Jos Domen, Aurélie Tormo, Jean-François Gauchat

“…Methods include measurement of the effect of CLCF-1 on phosphorylation of target molecules of the JAK/STAT pathway, on cytoskeleton and cell morphology in cultured podocytes, on albumin permeability of isolated rat glomeruli, and on tissue phosphorylation and urine albumin after acute or chronic CLCF-1 injection. …”
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Designing Gold Nanoparticle-Ensembles as Surface Enhanced Raman Scattering Tags inside Human Retinal Cells by Sanda Boca, Dumitrita Rugina, Adela Pintea, Nicolae Leopold, Simion Astilean

“…Typically, SERS tags are hybrid nanoconstructs consisting in a unique plasmonic nanoobject encoded with specific reporter molecules and enveloped in a protective shell that provides both biocompatibility and targeting function. …”
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Proteomics study of Mongolian medicine warm acupuncture in the treatment of p-chlorophenylalanine-induced insomnia in rats by Yanan Xu, Jianxun Wen, Wenyan Han, Gula A, Xiulan Su

“…Mongolian medical warm acupuncture (MMWA) therapy is a traditional external therapy method that has a definite clinical effect in the treatment of insomnia, but research on its underlying neural mechanisms remains limited. iTRAQ-based quantitative proteomics was used to identify proteins that are potential neural molecules involved in the treatment of insomnia by MMWA. …”
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Immunological Aspects of Fulminant Type 1 Diabetes in Chinese by Zhen Wang, Ying Zheng, Yiting Tu, Zhijie Dai, Jian Lin, Zhiguang Zhou

“…The mRNA levels of several related cytokines and molecules, such as IFN-γ, IL-4, RORC, and IL-17 in PBMCs from FT1D patients were analyzed by qRT-PCR. …”
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An emerging trend in Novel Psychoactive Substances (NPSs): designer THC by Cristian Caprari, Elena Ferri, Maria Angela Vandelli, Cinzia Citti, Giuseppe Cannazza

“…Despite the aim to encompass all known THC-like molecules, new species emerge on the drug users’ pipeline each month. …”
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Curcumin Protects Neonatal Rat Cardiomyocytes against High Glucose-Induced Apoptosis via PI3K/Akt Signalling Pathway by Wei Yu, Wenliang Zha, Zhiqiang Ke, Qing Min, Cairong Li, Huirong Sun, Chao Liu

“…Cell viability, apoptosis, superoxide formation, the expression of NADPH oxidase subunits, and potential regulatory molecules, Akt and GSK-3β, were assessed in cardiomyocytes. …”
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Graphene/TiO₂ Heterostructure Integrated with a Micro-Lightplate for Low-Power NO₂ Gas Detection by Paniz Vafaei, Margus Kodu, Harry Alles, Valter Kiisk, Olga Casals, Joan Daniel Prades, Raivo Jaaniso

“…The gas response amplitudes remained nearly constant over the studied light intensity range (1–150 mW/cm²) owing to the balance between the photoinduced adsorption and desorption processes of the gas molecules. The rates of both processes followed an approximately square-root dependence on light intensity, plausibly because the electron–hole recombination of photoinduced charge carriers is the primary rate-limiting factor. …”
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Inhibition of Ceramide De Novo Synthesis Ameliorates Diet Induced Skeletal Muscles Insulin Resistance by Krzysztof Kurek, Agnieszka Mikłosz, Bartłomiej Łukaszuk, Adrian Chabowski, Jan Górski, Małgorzata Żendzian-Piotrowska

“…Many researches indicate lipids, especially the one from the sphingolipids class, as the group of molecules heavily implicated in the progress of insulin resistance in skeletal muscle. …”
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Programming scheduled self-assembly of circadian materials by Gregor Leech, Lauren Melcher, Michelle Chiu, Maya Nugent, Shirlaine Juliano, Lily Burton, Janet Kang, Soo Ji Kim, Sourav Roy, Leila Farhadi, Jennifer L. Ross, Moumita Das, Michael J. Rust, Rae M. Robertson-Anderson

“…Abstract Active biological molecules present a powerful, yet largely untapped, opportunity to impart autonomous regulation of materials. …”
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Discovering natural products as potential inhibitors of SARS-CoV-2 spike proteins by Muhammad Alqaaf, Ahmad Kamal Nasution, Mohammad Bozlul Karim, Mahfujul Islam Rumman, Muhammad Hendrick Sedayu, Retno Supriyanti, Naoaki Ono, Md. Altaf-Ul-Amin, Shigehiko Kanaya

“…We subsequently identified 33,722 binding molecules (BMs) by matching them with the sequences of 204 S-glycoproteins and compared them with 52,107 secondary metabolites (SMs) from the KNApSAcK database to identify potential inhibitors. …”
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Targeting the epigenome with advanced delivery strategies for epigenetic modulators by Sonia Guha, Yogeswaran Jagadeesan, Murali Monohar Pandey, Anupama Mittal, Deepak Chitkara

“…Currently, a considerable amount of research is focused on discovering new drug molecules to combat the existing research gap in epigenetic drug therapy. …”
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