Investigation of the anti-aging effects of active components of Artemia franciscana loaded in hyalurosome by Mona Sadat Mirtaleb, Mahvash Khodabandeh Shahraky, Abdolkhaleg Deezagi, Danial Shafiee

“…In conclusion, hyalurosomes fabricated with Artemia franciscana extract and its diverse active molecules successfully achieved enhanced loading and penetration into the deeper layers of the skin, and it can be a suitable candidate for the treatment of skin aging and rejuvenation.…”
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A novel strategy for biomarker discovery: Neutral loss-dependent acquisition of circulating extracellular vesicles for the detection of phosphopeptides by Dong Wei, Hao Zhang, Mingyang Li, Liuxi Chu

“…Circulating extracellular vehicles (EVs) play a crucial role in intercellular communication by transporting a diverse array of biological signaling molecules. Growing evidence indicates that phosphoproteins within these EVs hold promise as biomarkers for diagnostic and prognostic assessments, particularly in oncology. …”
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AMPK: An energy sensor for non-small cell lung cancer progression and treatment by Zhi-Ting Zhong, Xu-Yan Wang, Ying Pan, Ke Zhou, Jing-Hui Chen, Yu-Qi Gao, Bo Dai, Zhi-Ling Zhou, Rui-Qi Wang

“…This review aims to examine the manifestations and mechanisms by which AMPK and its associated signalling molecules influence NSCLC progression and treatment. …”
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Advances in Drug Targeting, Drug Delivery, and Nanotechnology Applications: Therapeutic Significance in Cancer Treatment by Fatih Ciftci, Ali Can Özarslan, İmran Cagri Kantarci, Aslihan Yelkenci, Ozlem Tavukcuoglu, Mansour Ghorbanpour

“…The nanocarrier-based drug delivery method involves encapsulating target-specific drug molecules into polymeric or vesicular systems. Various drug delivery systems (DDS) were investigated and discussed in this review article. …”
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Genetics of Myasthenia Gravis: A Case-Control Association Study in the Hellenic Population by Zoi Zagoriti, Marianthi Georgitsi, Olga Giannakopoulou, Fotios Ntellos, Socrates J. Tzartos, George P. Patrinos, Konstantinos Poulas

“…These are interferon regulatory factor 5 (IRF-5), TNFα-induced protein 3 (TNFAIP3), also known as A20, and interleukin-10 (IL-10), key molecules in the regulation of immune function. A statistical trend of association (P=0.068) between IL-10 promoter single nucleotide polymorphisms (SNPs) and the subgroups of early and late-onset MG patients was revealed. …”
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CO Adsorption Properties of Activated Carbon Fibres under Ambient Conditions by Yoshitaka Nakahigashi, Hirofumi Kanoh, Tomonori Ohba, Masumi Baba, Yoshiyuki Hattori, Naoya Inoue, Masafumi Morimoto

“…By establishing the temperature dependence of CO 2 adsorptivity and using Dubinin–Radushkevich analysis, we characterized the interaction energy between pores and CO 2 molecules. Our results shed light on the fundamental aspects of CO 2 adsorption of ACFs, moving them towards being a viable CCS.…”
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Effect of non-starch polysaccharides and butterfly pea flower on the in vitro digestibility of glutinous rice by Jamie Xiu Qing Siah, Teck Ann Ong, Oni Yuliarti, Joshua Ding Wei Teo

“…The findings suggest that C5 and BPF influenced the digestibility and textural properties of GR through their interactions with starch molecules and ability to form a protective layer around the rice grains. …”
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NCOA4 linked to endothelial cell ferritinophagy and ferroptosis:a key regulator aggravate aortic endothelial inflammation and atherosclerosis by Li Zhu, Zijian Liu, Jiahui Liu, Zhenglong Li, Youli Bao, Xin Sun, Wenchen Zhao, An Zhou, Hongfei Wu

“…Collectively, our results provide evidence of a connection between NCOA4-mediated promotion of AS and suggest that targeting upstream molecules regulating NCOA4 could be a potential therapy for AS.…”
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Magnesium hydride protects against acetaminophen-induced acute kidney injury by inhibiting TXNIP/NLRP3/nf-κb pathway by Yachen Si, Lulu Liu, Yinyin Zhang, Hongxia Li, Tingting Zhao, Su Liu, Xuejun Sun, Jin Cheng, Hongtao Lu

“…Furthermore, the expressions of molecules related to TXNIP/NLRP3/NF-κB pathway (TXNIP, NLRP3, NF-κB p65 and p-NF-κB p65) in renal tissues and HK-2 cells were enhanced by APAP overdose, which were reduced by MgH2 administration. …”
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Dye-Sensitized Nanocrystalline ZnO Solar Cells Based on Ruthenium(II) Phendione Complexes by Hashem Shahroosvand, Parisa Abbasi, Mohsen Ameri, Mohammad Reza Riahi Dehkordi

“…FT-IR and absorption spectra showed the favorable interfacial binding between the dye-molecules and ZnO surface. The surface analysis and size of adsorbed dye on nanostructure ZnO were further examined with AFM and SEM. …”
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Characterization and potential use of olive pies from different extractions and industries in ruminant feeding by F. A. Rizzo, J. Schafhäuser Jr., A. C. Fluck, R. B. Scheibler, J. L. Nörnberg, D. P. Vargas, O. A. D. Costa, L. A. Lourenço, G. O. Suzin

“…These results demonstrate that the byproduct represents a potential source of lipids and phenolic compounds that can be used to adjust diets as well as the aggregation of functional molecules in meat and milk products. The care in obtaining and preserving the product is important because the material obtained 48 hours after the processing showed losses in the contents of CHO, CNF, FT and TT, which can impair its nutritional value and the potential of use. …”
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A Refined Nomenclature System to Better Discriminate Endo- and Exo-Type Fructanases and Glucanases by Laura Leaerts, Jaime Ricardo Porras-Domínguez, Maxime Versluys, Wim Van den Ende

“…Our refined nomenclature system will advance enzyme structure–function research and support the production and application of fructan and glucan oligosaccharides as prebiotics, priming agents, and potential signaling molecules in microbe–microbe and plant–microbe interactions. …”
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Magnetic and pH sensitive nanocomposite microspheres for controlled temozolomide delivery in glioblastoma cells by Meysam Ahmadi, Muhammad Hossein Ashoub, Kamran Heydaryan, Sanaz Abolghasemi, Elmuez A. Dawi, Ghazal khajouei, Mahnaz Amiri

“…The release percentage of temozolomide molecules in the presence of 100 Hz reached a maximum in 90 min. …”
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Exploring the Structural Diversity and Biotechnological Potential of the Rhodophyte Phycolectome by Éllen F. Rodrigues, Flavia Alves Verza, Felipe Garcia Nishimura, Renê Oliveira Beleboni, Cedric Hermans, Kaat Janssens, Maarten Lieven De Mol, Paco Hulpiau, Mozart Marins

“…Moreover, their diversity enables biotechnological exploration as biomarkers, biosensors, drug-delivery platforms, and lead molecules for anticancer, antidiabetic, and antimicrobial drugs. …”
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A cGAMP‐Containing Hydrogel for Prolonged SARS‐CoV‐2 Receptor‐Binding Domain Subunit Vaccine Exposure Induces a Broad and Potent Humoral Response by Volker Böhnert, Emily C. Gale, Lauren J. Lahey, Jerry Yan, Abigail E. Powell, Ben S. Ou, Jacqueline A. Carozza, Lingyin Li, Eric A. Appel

“…To overcome these limitations, it is sought to create an artificial immunological niche enabling the slow release of cGAMP and RBD to mimic natural infections in which immune‐activating molecules are colocalized with antigen. Specifically, through coencapsulation of cGAMP and RBD in an injectable polymer‐nanoparticle (PNP) hydrogel, the cGAMP‐adjuvanted hydrogel vaccine elicits more potent, durable, and broad antibody responses with improved neutralization as compared to dose‐matched bolus controls and hydrogel‐based vaccines lacking cGAMP. …”
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New Insights in the Pathogenesis of HPV Infection and the Associated Carcinogenic Processes: The Role of Chronic Inflammation and Oxidative Stress by Simona Roxana Georgescu, Cristina Iulia Mitran, Madalina Irina Mitran, Constantin Caruntu, Maria Isabela Sarbu, Clara Matei, Ilinca Nicolae, Sandra Milena Tocut, Mircea Ioan Popa, Mircea Tampa

“…Chronic inflammation induces OS, which in turn promotes the perpetuation of the inflammatory process resulting in the release of numerous molecules which cause cell damage. Reactive oxygen species exert a harmful effect on proteins, lipids, and nucleic acids. …”
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Attempted Depletion of Passenger Leukocytes by Irradiation in Pigs by Hao-Chih Tai, Xiaocheng Zhu, Yih Jyh Lin, Hidetaka Hara, Mohamed Ezzelarab, Michael Epperley, Mubina A. Quader, David K. C. Cooper

“…The lack of effect may have been related to (i) inadequate depletion of passenger leukocytes, thus not preventing a direct T cell response, (ii) the presence of dead or dying leukocytes (antigens), thus not preventing an indirect T cell response, or (iii) constitutive expression of MHC class II and B7 molecules on the porcine vascular endothelium, activating recipient T cells.…”
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The Importance of Ubiquitination and Deubiquitination in Cellular Reprogramming by Bharathi Suresh, Junwon Lee, Kye-Seong Kim, Suresh Ramakrishna

“…There are two switches: an E3 ubiquitin ligase enzyme that tags ubiquitin molecules to the target proteins for proteolysis and a second enzyme, the deubiquitinating enzyme (DUBs), that performs the opposite action, thereby preventing proteolysis. …”
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Flow Cytometric Detection of p38 MAPK Phosphorylation and Intracellular Cytokine Expression in Peripheral Blood Subpopulations from Patients with Autoimmune Rheumatic Diseases by Athanasios Mavropoulos, Dimitrios P. Bogdanos, Christos Liaskos, Timoklia Orfanidou, Theodora Simopoulou, Efterpi Zafiriou, Lazaros I. Sakkas, Eirini I. Rigopoulou

“…We have also tested surface markers of costimulatory molecules, such as CD27. We have successfully determined simultaneous expression of IFN-γ, as well as IL-10, and phosphorylated p38 in cell subsets. …”
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MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations by Athanasia Tsaousi, Ellen Witte, Katrin Witte, Hans-Joachim Röwert-Huber, Hans-Dieter Volk, Wolfram Sterry, Kerstin Wolk, Sylke Schneider-Burrus, Robert Sabat

“…Here, we demonstrate that one of the most highly upregulated molecules in AI lesions is matrix metalloproteinase 8 (MMP8), an enzyme specialized in the degradation of extracellular matrix components and the HDL component apolipoprotein A-I. …”
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