Molecular surface descriptors to predict antibody developability: sensitivity to parameters, structure models, and conformational sampling by Eliott Park, Saeed Izadi

“…Based on our benchmarking analysis, we propose six in silico developability risk flags and assess their effectiveness in predicting potential developability issues for a set of case study molecules.…”
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In Vivo Method to Monitor Changes in HER2 Expression Using Near-Infrared Fluorescence Imaging by Moinuddin Hassan, Victor Chernomordik, Rafal Zielinski, Yasaman Ardeshirpour, Jacek Capala, Amir Gandjbakhche

“…We used albumin binding domain–fused HER2-specific Affibody molecules, labeled with Alexa Fluor750 dye, to characterize HER2 expression in vivo. …”
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Inflammasomes, Autophagy, and Cell Death: The Trinity of Innate Host Defense against Intracellular Bacteria by Teresa Krakauer

“…Common downstream signaling molecules of inflammasomes, autophagy, and cell death pathways interact to initiate appropriate measures against pathogens and determine host survival as well as pathological consequences of infection. …”
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Altered microbiome and metabolome profiling in fearful companion dogs: An exploratory study. by Luigi Sacchettino, Michele Costanzo, Iolanda Veneruso, Valeria D'Argenio, Maria Mayer, Francesco Napolitano, Danila d'Angelo

“…Moreover, serum metabolomics documented significant alterations of molecules associated to GABA and glutamate neurotransmission in the patients, as well as bile acids metabolism. …”
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Colour Removal from Dye Wastewater Using Sugar Cane Dust as an Adsorbent by S.D. Khattri, M.K. Singh

“…The equilibrium data obey the requirements of the Langmuir adsorption model, demonstrating the formation of a monolayer of dye molecules on the outer surface of the adsorbent. The variation in the extent of removal with pH has been explained on the basis of surface ionisation and complexation. …”
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Chloramphenicol and gentamicin reduce the evolution of resistance to phage ΦX174 by suppressing a subset of E. coli LPS mutants. by Lavisha Parab, Jordan Romeyer Dherbey, Norma Rivera, Michael Schwarz, Jenna Gallie, Frederic Bertels

“…Bacteriophages infect gram-negative bacteria by attaching to molecules present on the bacterial surface, often lipopolysaccharides (LPS). …”
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Adenosine A2A Receptors Modulate Acute Injury and Neuroinflammation in Brain Ischemia by Felicita Pedata, Anna Maria Pugliese, Elisabetta Coppi, Ilaria Dettori, Giovanna Maraula, Lucrezia Cellai, Alessia Melani

“…Proinflammatory cytokines, which upregulate cell adhesion molecules, exert an important role in promoting recruitment of leukocytes that in turn promote expansion of the inflammatory response in ischemic tissue. …”
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Total Electrosynthesis of N, N‐Dimethylformamide From CO2 and NO3− by Shuai Yan, Shuai Chen, Morgan McKee, Alexandre Terry, Ralf Weisbarth, Nikolay Kornienko

“…Abstract Electrochemical C−N coupling presents a promising strategy for converting abundant small molecules like CO2 and NO3− to produce low‐carbon‐intensity chemicals in a potentially more sustainable route. …”
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Urinary Levels of IL-1β and GDNF in Preterm Neonates as Potential Biomarkers of Motor Development: A Prospective Study by Rafael Coelho Magalhães, Janaina Matos Moreira, Érica Leandro Marciano Vieira, Natália Pessoa Rocha, Débora Marques Miranda, Ana Cristina Simões e Silva

“…Maternal age, plasma, and urinary concentrations of inflammatory molecules and neurotrophic factors were significantly different between groups with normal versus lower than expected motor development. …”
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Mechanism of Repeat-Associated MicroRNAs in Fragile X Syndrome by Karen Kelley, Shin-Ju E. Chang, Shi-Lung Lin

“…After transcription, the trinucleotide repeats can fold into RNA hairpins and are further processed by Dicer endoribonuclases to form microRNA (miRNA)-like molecules that are capable of triggering targeted gene-silencing effects in the TREDs. …”
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Effect of flowrate on the size segregation of magnetic nanoparticles by using continuous flow magnetic separator by Khew Chung Wei, Ng Wei Ming, Leong Sim Siong, Wong Ling Yong, Toh Pey Yi

“…To produce MNPs that are monodispersed, firstly, MNPs undergo functionalization with the polyelectrolyte, poly (sodium 4-styrene sulfonate) (PSS), to enhance colloidal stability. Employing PSS molecules as splicing agents effectively inhibits MNP aggregation. …”
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Protection against the Phytotoxic Effect of Mercury Chloride by Catechin and Quercetin by Yedda M. L. S. de Matos, Daniel L. M. Vasconcelos, Antonio C. H. Barreto, Janaína E. Rocha, José B. de Araújo-Neto, Fábia F. Campina, Maria Milene C. da Silva, Tássia T. Al Yafawi, Celestina E. Sobral-Souza, Jacqueline C. A. Pinheiro, Saulo R. Tintino, Amanda K. Sousa, Raimundo N. P. Teixeira, Juan C. Alvarez-Pizarro, João H. da Silva, Abolghasem Siyadatpanah, Bonglee Kim, Henrique D. M. Coutinho

“…Plants when exposed to toxic levels of metals can suffer morphological or physiological damage because toxic metals can interact with several vital molecules in the plant. One possibility to remove these contaminants from the environment is through the phytoremediation technique, since secondary metabolites produced by plants can reverse these damages. …”
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Interleukin-1 signaling and CD4+ T cells control B cell recruitment to the lungs in chronic beryllium disease by Joseph M. Gaballa, Caley Valdez, Douglas G. Mack, Faiz Minhajuddin, Masoom Raza, Tabrez A. Mohammad, Allison K. Martin, Andrew Getahun, Charles A. Dinarello, Andrew P. Fontenot, Shaikh M. Atif

“…However, the mechanisms by which innate molecules influence the recruitment of B cells and B cell-mediated protection in CBD are poorly understood. …”
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Synthesis and Structural Insight into the Bioactivity of Imines with 1,5-Dimethyl-2-Phenyl-1H-Pyrazol-3(2H)-One Structural Unit Derived from Phenolic Aldehydes by Muamer Dizdar, Anela Topčagić, Monia Avdić, Danijela Vidic, Milka Maksimović

“…This comprehensive analysis demonstrates the significant potential of these synthesised imines as bioactive molecules, offering insights into how structural modifications can enhance their biological functions.…”
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Polarization of ILC2s in Peripheral Blood Might Contribute to Immunosuppressive Microenvironment in Patients with Gastric Cancer by Qingli Bie, Pan Zhang, Zhaoliang Su, Dong Zheng, Xinyu Ying, Yumin Wu, Huijian Yang, Deyu Chen, Shengjun Wang, Huaxi Xu

“…In this study, the ILC2s related genes or molecules in PBMC from patients with gastric cancer were measured, and the potential correlation between them was analyzed. …”
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Aronia melanocarpa Leaves as a Source of Chlorogenic Acids, Anthocyanins, and Sorbitol, and Their Anti-Inflammatory Activity by Agnieszka Zielińska, Dorota Bryk, Katarzyna Paradowska, Iwona Wawer

“…Both extracts suppressed TNF-α-induced surface expression of ICAM-1 and VCAM-1 molecules, and exhibited anti-adhesive and anti-inflammatory properties. …”
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Dynamics of Proteins by Thermal Decay of Free Radicals Induced by Ultraviolet Irradiation by Rasim B. Aslanov, Leman M. Dashdemirova, Oktay Z. Alekperov, Azad R. Abdurahimov, Oktay K. Gasymov

“…The thermal transitions at 205 K and 279 K are weakly and strongly, respectively, coupled to water molecules. Nature of the free radicals participated in these transitions was identified. …”
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Targeted Photodynamic Therapy: A Novel Approach to Abolition of Human Cancer Stem Cells by Anine Crous, Elvin Chizenga, Natasha Hodgkinson, Heidi Abrahamse

“…Currently, PDT is being investigated as a target specific treatment for CSCs by the addition of carrier molecules and antibody conjugates bound to the PS. …”
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Development of Active CO2 Emission Control for Diesel Engine Exhaust Using Amine-Based Adsorption and Absorption Technique by Solomon Jenoris Muthiya, L. Natrayan, L. Yuvaraj, Mohankumar Subramaniam, Joshuva Arockia Dhanraj, Wubishet Degife Mammo

“…An amine-based liquid is used to adsorb the CO2 molecules first and absorb over the amines from the diesel engine exhaust. …”
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Antioxidant and cytotoxic activities of 2-oxo-1,2,3,4-tetrahydropyrimidines by Sarosh Iqbal, Shahida Perveen, M. Iqbal Choudhary, Musarrat Jabeen, Shumaila Kiran, Faiza Qayyum, Khalid Mohammed Khan

“…It contributes to the onset and progression of chronic inflammation, cancers, diabetes mellitus, atherosclerosis, Alzheimer’s disease, ocular disease, nephropathy, and premature aging. The molecules known as antioxidants contribute significantly to both the prevention and exaggeration of ailments. …”
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