He-Plasma Jet Generation and Its Application for E. coli Sterilization by Tiejian Liu, Yuxuan Zeng, Xin Xue, Yinyi Sui, Yingying Liang, Fushan Wang, Fada Feng

“…The optic emission spectra suggest that active species such as excited molecules, ions, and radicals were produced in the He-APPJ. …”
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Molecular dynamics-guided reaction discovery reveals endoperoxide-to-alkoxy radical isomerization as key branching point in α-pinene ozonolysis by Huan Yang, Umberto Raucci, Siddharth Iyer, Galib Hasan, Thomas Golin Almeida, Shawon Barua, Anni Savolainen, Juha Kangasluoma, Matti Rissanen, Hanna Vehkamäki, Theo Kurtén

“…Although the oxidation of volatile organic compounds (VOCs) has been recognized as the major contributor to the atmospheric SOA budget, the mechanisms by which this process produces SOA-forming highly oxygenated organic molecules (HOMs) remain unclear. A major challenge is navigating the complex chemical landscape of these transformations, which traditional hypothesis-driven methods fail to thoroughly investigate. …”
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RBP-Tar – a searchable database for experimental RBP binding sites [version 3; peer review: 1 approved, 2 approved with reservations] by Panagiotis Alexiou, David Cechak, Radka Svobodova, Tomas Racek, Vlastimil Martinek, Katarina Gresova

“…Background RNA-binding proteins (RBPs) play a critical role in regulating gene expression by binding to specific sites on RNA molecules. Identifying these binding sites is crucial for understanding the many functions of RBPs in cellular function, development and disease. …”
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Prebiotic Geochemical Automata at the Intersection of Radiolytic Chemistry, Physical Complexity, and Systems Biology by Zachary R. Adam, Albert C. Fahrenbach, Betul Kacar, Masashi Aono

“…In this paper, we map out stratified relationships between physical components that drive the production of key prebiotic molecules starting from radiolysis of a small number of abundant molecular species. …”
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Highly Porous Carbon Materials from Biomass by Chemical and Carbonization Method: A Comparison Study by Wan Nor Roslam Wan Isahak, Mohamed Wahab Mahamed Hisham, Mohd Ambar Yarmo

“…At room temperature (without heating), treatment of H2SO4 removed all the water molecules in the biomass and left the porous carbon without emitting any gaseous byproducts. …”
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Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow Colostrum by Lunbo Tan, Ting Wei, Anwen Yuan, Jun He, Jinhui Liu, Daojun Xu, Qing Yang

“…Colostrum is the main external resource providing piglets with nutrients and maternal immune molecules. Astragalus polysaccharides (APS) have been used as immunopotentiators in vitro and several animal models. …”
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Wettability of Polar and Apolar Liquids on Metal Surfaces by Mohanad Khairi, Zoltán Erdélyi, Peter Baumli

“…The intermolecular interactions between oil molecules and the metal surface primarily influence the wetting of a metal surface by different types of oil. …”
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Induction of tyrosine aminotransferase in mice is inhibited by activated metabolites of ortho- aminoazotoluene by V. I. Kaledin, S. I. Ilnitskaya, N. A. Popova, O. A. Koval, I. A. Pyshnaya, L. F. Gulyaeva

“…The results unequivocally confirm that glucocorticoid induction of TAT activity in mouse liver is inhibited by activated metabolite(s) of OAT rather than by its intact molecules. In contrast, nonspecific genotoxic agents such as cyclophosphamide and cisplatin exert no effect on TAT induction by glucocorticoids. …”
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Encapsulated LyeTx III Peptide: Cytotoxic Agent Isolated from <i>Lycosa erythrognatha</i> Spider Venom by Daniel Moreira dos Santos, Livia Ramos Santiago, Nayara Araújo dos Santos, Wanderson Romão, Jarbas Magalhães Resende, Maria Elena de Lima, Márcia Helena Borges, Rosy Iara Maciel de Azambuja Ribeiro

“…Antimicrobial peptides are an interesting class of molecules for this endeavor. In this context, the LyeTx III, a new peptide extracted from the venom of the <i>Lycosa erythrognatha</i> spider, stands out. …”
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Design of double oxygen vacancy-rich Bi2O2S0.8F0.4/BiOBr S-scheme heterojunction via tuning band structure for CO2 photoreduction by Xifeng Hou, Chenbin Ai, Songyu Yang, Jianjun Zhang, Yanfeng Zhang, Jingze Liu

“…Moreover, the presence of dual oxygen vacancies on the interfacial surface of Bi2O2S0.8F0.4/BiOBr heterojunction facilitates the adsorption and activation of CO2 and H2O molecules. The work focuses on the combined impact of the S-scheme band structure and oxygen vacancy on the property of photocatalytic reduction of CO2. …”
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Creating burdock polysaccharide-oleanolic acid-ursolic acid nanoparticles to deliver enhanced anti-inflammatory effects: fabrication, structural characterization and property evalu... by Shanshan Zhu, Zhichang Qiu, Xuguang Qiao, Geoffrey I.N. Waterhouse, Wenqing Zhu, Wenting Zhao, Qiuxia He, Zhenjia Zheng

“…Therefore, ALP-based nanoparticles are natural and anti-inflammatory carriers for hydrophobic bioactive molecules.…”
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Adherent junctions: Physiology, role in hydrocephalus and potential therapeutic targets by Zhiye Chen, Jian He, Yating Guo, Yue Hao, Wentao Lv, Zexin Chen, Junqiang Wang, Yijian Yang, Kaiyue Wang, Zhikun Liu, Qian Ouyang, Zhangjie Su, Pingsheng Hu, Gelei Xiao

“…At present, the researches on the pathogenesis of hydrocephalus are mainly focused on the development of ependymal cells and cilia, while less attention has been paid to molecules such as AJs, which play an important role in maintaining the polarity of ependymal cells. …”
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Viroids and Retrozymes: Plant Circular RNAs Capable of Autonomous Replication by Alexander A. Lezzhov, Anastasia K. Atabekova, Denis A. Chergintsev, Ekaterina A. Lazareva, Andrey G. Solovyev, Sergey Y. Morozov

“…Among the long non-coding RNAs that are currently recognized as important regulatory molecules influencing a plethora of processes in eukaryotic cells, circular RNAs (circRNAs) represent a distinct class of RNAs that are predominantly produced by back-splicing of pre-mRNA. …”
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The role of the interplay between macrophage glycolytic reprogramming and NLRP3 inflammasome activation in acute lung injury/acute respiratory distress syndrome by Lan Luo, Xiaoli Zhuang, Lin Fu, Ziyuan Dong, Shuyuan Yi, Kan Wang, Yu Jiang, Ju Zhao, Xiaofang Yang, Feilong Hei

“…This activation drives pulmonary inflammation by releasing inflammatory signalling molecules and is linked to metabolic reprogramming, marked by increased glycolysis and reduced oxidative phosphorylation. …”
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A machine learning based classifier for topological quantum materials by Ashiqur Rasul, Md Shafayat Hossain, Ankan Ghosh Dastider, Himaddri Roy, M. Zahid Hasan, Quazi D. M. Khosru

“…The incorporation of the graph neural network encodes the underlying relation between the atoms into the model based on their crystalline structures and thus proved to be an effective method to represent and process non-Euclidean data like molecules with a relatively shallow network. The persistent homology pipeline in the proposed neural network integrates a topological analysis of crystal structures into the deep learning model, enhancing both robustness and performance. …”
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The Oxytocin-Oxytocin Receptor System and Its Antagonists as Tocolytic Agents by Nikolaos Vrachnis, Fotodotis M. Malamas, Stavros Sifakis, Efthymios Deligeoroglou, Zoe Iliodromiti

“…However, the quest for oxytocin receptor antagonists with a better pharmacological profile has led to the synthesis of peptide and nonpeptide molecules such as barusiban, retosiban, L-368,899, and SSR-126768A. …”
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Evaluation of the immunological functions of placental alkaline phosphatase in vivo using ALPP transgenic mice by Tse-Ching Chen, Kwai-Fong Ng, Ning Chen, Yi-Ling Pan, Chun-An Cheng, Hsiao-Chun Wu, Yi-Jen Hsueh, Nien-Yi Chiang, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin

“…ALP is also considered as an anti-inflammatory protein due to its ability to dephosphorylate and inactivate inflammation-triggering molecules such as lipopolysaccharide (LPS). Placental alkaline phosphatase (ALPP) is one of tissue-specific ALP isozymes expressed mostly during pregnancy, however it was found to be differentially upregulated in certain hepatocellular carcinomas by us recently. …”
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A Review of the Utility of Established Cell Lines for Isolation and Propagation of the Southern African Territories Serotypes of Foot-and-Mouth Disease Virus by Kitsiso Gaboiphiwe, Tshephang Iris Kabelo, Petronella Thato Mosholombe, Joseph Hyera, Elliot Mpolokang Fana, Kabo Masisi, Kebaneilwe Lebani

“…This review highlights how different receptors and molecules—integrins, heparan sulphate (HS), and the Jumonji C-domain containing Protein 6 (JMJD6)—found on the surface of different cell types contribute to differences experienced with susceptibility and sensitivity of the cells to infection with different serotypes of FMDV. …”
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Synthesis and Experimental Validation of New PDI Inhibitors with Antiproliferative Activity by Mariateresa Badolato, Gabriele Carullo, Francesca Aiello, Antonio Garofalo

“…Besides acting as a protein folding catalyst, several evidences have suggested that PDI can bind small molecules containing, for example, a phenolic structure, which includes the estrogenic one. …”
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Application of a Plug-and-Play Immunogenicity Assay in Cynomolgus Monkey Serum for ADCs at Early Stages of Drug Development by Montserrat Carrasco-Triguero, Helen Davis, Yuda Zhu, Daniel Coleman, Denise Nazzal, Paul Vu, Surinder Kaur

“…This assay showed good sensitivity, drug tolerance, and reproducibility across a variety of antibody-derived biotherapeutics without the need for optimization across molecules.…”
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