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  1. 3701

    The Global Assessment of Oilseed Brassica Crop Species Yield, Yield Stability and the Underlying Genetics by Jaco D. Zandberg, Cassandria T. Fernandez, Monica F. Danilevicz, William J. W. Thomas, David Edwards, Jacqueline Batley

    Published 2022-10-01
    “…The family of Brassicaceae crops are no exception, typically harvested as a valuable source of oil, rich in beneficial molecules important for human health. The global capacity for improving <i>Brassica</i> yield has steadily risen over the last 50 years, with the major crop <i>Brassica napus</i> (rapeseed, canola) production increasing to ~72 Gt in 2020. …”
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  2. 3702

    Effect of plasma free fatty acids on lung function in male COPD patients by Rostam Yazdani, Hossein Fallah, Shirin Yazdani, Beydolah Shahouzehi, Behnaz Danesh

    Published 2025-01-01
    “…Free fatty acids (FFA) as signaling molecules through a series of G-proteins coupled receptors, play an important role in regulation of the immune system and oxidative stress. …”
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  3. 3703

    Frontiers in Vitamin Research: New Antibodies, New Data by Rafael Coveñas, Arturo Mangas, Dominique Bodet, Sébastien Duleu, Pilar Marcos, Begum Karakas, Michel Geffard

    Published 2011-01-01
    “…At present, there are insufficient data to elucidate the roles played by vitamins in the brain, but the anatomical distribution of these compounds in the monkey brain provides a general idea (although imprecise and requiring much more study) about the possible functional implications of these molecules. In this sense, here the possible functional roles played by vitamins are discussed.…”
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  4. 3704

    Improving ferroptosis-mediated immunotherapy for colorectal cancer through lysosome-targeted photodynamic therapy by Zhian Chen, Yutong Wang, Zhenhao Li, Meijuan Chen, Yingshi Li, Chuyue Lu, Zhenyu Lin, Hua Zheng, Lujia Chen, Qianbing Zhang

    Published 2025-04-01
    “…Subsequently, the cancer cells were suffered from ferroptosis through triggering cell-intrinsic Fenton chemistry and mitochondrial dysfunction, which would release damage-associated molecular pattern molecules (DAMPs) to induce immunogenic cell death and remodel immunosuppressive tumor microenvironment. …”
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  5. 3705

    Inflammation and Inflammasomes: Pros and Cons in Tumorigenesis by Liliana R. Balahura, Aida Selaru, Sorina Dinescu, Marieta Costache

    Published 2020-01-01
    “…Additionally, microRNAs (miRNAs), evolutionary conserved noncoding molecules, have emerged as pivotal players during numerous biological events by regulating gene and protein expression. …”
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  6. 3706

    Synthetic Peptides as Potential Antigens for Cutaneous Leishmaniosis Diagnosis by Juliana Seger Link, Silvana Maria Alban, Carlos Ricardo Soccol, Gilberto Vinicius Melo Pereira, Vanete Thomaz Soccol

    Published 2017-01-01
    “…These results show a new route for discovering molecules for diagnosis or for immunoprotection against leishmaniosis.…”
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  7. 3707

    Highly sensitive, responsive, and selective iodine gas sensor fabricated using AgI-functionalized graphene by Zhuo Chen, Qiong Lei, Yinchang Ma, Jinrong Wang, Yuan Yan, Jun Yin, Jiaqiang Li, Jie Shen, Guanxing Li, Tingting Pan, Xinglong Dong, Bambar Davaasuren, Yaping Zhang, Jefferson Zhe Liu, Jun Tao, Yu Han

    Published 2025-01-01
    “…The AgI particles enable reversible adsorption and conversion of I2 molecules into polyiodides, inducing substantial charge density variation in rGO. …”
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  8. 3708

    Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation by Adam Aguirre, Carola J. Maturana, Paloma A. Harcha, Juan C. Sáez

    Published 2013-01-01
    “…Mastocytes and glial cells express different toll-like receptor (TLR) family members, and their activation via proinflammatory molecules can increase the expression of connexin hemichannels and pannexin channels in glial cells. …”
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  9. 3709

    MAGEB2-Mediated Degradation of EGR1 Regulates the Proliferation and Apoptosis of Human Spermatogonial Stem Cell Lines by Xueheng Zhao, Zenghui Huang, Yongzhe Chen, Qianyin Zhou, Fang Zhu, Huan Zhang, Dai Zhou

    Published 2023-01-01
    “…Understanding the mechanisms underlying SSC fate decisions is critical for controlling spermatogenesis and male fertility. However, the key molecules and mechanisms responsible for regulating human SSC development are not clearly understood. …”
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  10. 3710

    <i>Pneumocystis</i> Pneumonia Severity Is Associated with Taxonomic Shifts in the Respiratory Microbiota by Valentina Del Prete, Antonia Piazzesi, Matteo Scanu, Francesca Toto, Stefania Pane, Federica Berrilli, Giovangiacinto Paterno, Lorenza Putignani, David di Cave

    Published 2025-01-01
    “…Functionally, severe PCP was associated with a decrease in metabolic pathways of molecules with anti-inflammatory and antimicrobial properties. …”
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  11. 3711

    Cytokine-armed pyroptosis induces antitumor immunity against diverse types of tumors by Sara Orehek, Taja Železnik Ramuta, Duško Lainšček, Špela Malenšek, Martin Šala, Mojca Benčina, Roman Jerala, Iva Hafner-Bratkovič

    Published 2024-12-01
    “…Careful selection of immunostimulatory molecules is, however, imperative as a combination of IL-1β and IL-18 antagonized the protective effect of pyroptosis by IFNγ-mediated upregulation of several immunosuppressive pathways. …”
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  12. 3712

    Exploring salinity induced adaptations in marine diatoms using advanced photonic techniques by Julijana Cvjetinovic, Yekaterina D. Bedoshvili, Nickolai A. Davidovich, Eugene G. Maksimov, Ekaterina S. Prikhozhdenko, Daria A. Todorenko, Daria V. Bodunova, Olga I. Davidovich, Igor S. Sergeev, Dmitry A. Gorin

    Published 2024-12-01
    “…Key findings include a systematic shift in the mean fluorescence lifetime from 570 ps at 20‰ to 940 ps at 80‰, indicating functional adaptations in chlorophyll molecules within light-harvesting complexes. At 60‰ salinity, anomalies are observed in the development of silica valves and polysaccharide layers, suggesting abnormalities in valve morphogenesis. …”
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  13. 3713

    Intestinal permeability and contractility in murine colitis by M. E. van Meeteren, J. D. van Bergeijk, A. P. M. van Dijk, C. J. A. M. Tak, M. A. C. Meijssen, F. J. Zijlstra

    Published 1998-01-01
    “…Distal colon segments were less permeable to 3H-mannitol and 14C-PEG 400 molecules compared with proximal colon and ileum. Intestinal permeability in control vs. 10% DSS mice was not altered, although histologic inflammation score and IFN-γ pro-inflammatory cytokine levels were significantly increased in proximal and distal colon. …”
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  14. 3714

    A New Hope in Immunotherapy for Malignant Gliomas: Adoptive T Cell Transfer Therapy by Dong-Sup Chung, Hye-Jin Shin, Yong-Kil Hong

    Published 2014-01-01
    “…Moreover, enhanced biologic functions of T cells generated by genetic engineering and modified immunosuppressive microenvironment of host by homeostatic T cell expansion and/or elimination of immunosuppressive cells and molecules can induce more potent antitumor T cell responses and make this strategy hold promise in promoting a patient response for malignant glioma treatment. …”
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  15. 3715

    Enter the Matrix: Fibroblast-immune cell interactions shape extracellular matrix deposition in health and disease. [version 2; peer review: 1 approved, 2 approved with reservations... by Anthony Altieri, Grace V. Visser, Matthew B. Buechler

    Published 2024-12-01
    “…Fibroblasts can directly and indirectly regulate immune responses by secreting ECM and ECM-bound molecules to shape tissue structure and influence organ function. …”
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  16. 3716

    Pathogenic Roles of Macrophage Migration Inhibitory Factor during Dengue Virus Infection by Yung-Chun Chuang, Hong-Ru Chen, Trai-Ming Yeh

    Published 2015-01-01
    “…The expression of both adhesion and coagulation molecules on MIF-stimulated monocytes and endothelial cells is also increased, which may contribute to inflammatory and anticoagulatory states during DHF/DSS. …”
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  17. 3717

    Flowers: precious food and medicine resources by Xuqiang Liu, Senye Wang, Lili Cui, Huihui Zhou, Yuhang Liu, Lijun Meng, Sitan Chen, Xuefeng Xi, Yan Zhang, Wenyi Kang

    Published 2023-07-01
    “…Flower plants are popular all over the world and important sources of ornamental plants, bioactive molecules and nutrients. Flowers have a wide range of biological activities and beneficial pharmacological effects. …”
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  18. 3718

    Interfacing exogenous stents with human coronary artery by self-assembled coating: designs, functionalities and applications by Feng Zhao, Feng Liu, Chenglong Gao, Guoqing Wang, Yinfeng Zhang, Fei Yu, Jiawei Tian, Kai Tan, Runhao Zhang, Kang Liang, Zhexun Lian, Junjie Guo, Biao Kong, Junbo Ge, Hui Xin

    Published 2024-05-01
    “…Additionally, we examine how self-assembled coatings have been used to release active molecules for anti-coagulation and deliver gene therapy. …”
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  19. 3719

    Synthesis of Surfactants Derived from 2-Mercaptobenzimidazole and Study of Their Acute Toxicity and Analgesic and Psychotropic Activities by Terence Nguema Ongone, Latyfa El Ouasif, Mostafa El Ghoul, Redouane Achour, Hind Chakchak, Meryem El Jemli, Yahia Cherrah, Katim Alaoui, Amina Zellou

    Published 2019-01-01
    “…The acute toxicity of these salts is evaluated according to OECD 423 Guidelines at the doses of 300 and 2000 mg/kg; their peripheral analgesic effect is studied using the Koster test at the therapeutic dose of 200 mg/kg and their sedative action is evaluated using Traction, Chimney, Hole-board, and Rotarod tests at the doses of 200 and 400 mg/kg. All synthesized molecules show no acute toxicity according to OECD Code 423 guidelines at doses ranging from 300 to 2000 mg/kg and do not cause any obesity or anorexia. …”
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  20. 3720

    Antioxidant Activity and Isolation of Luteoline from Centaurea behen L. Grown in Iran by Akbar Esmaeili, Zahra Mousavi, Maryam Shokrollahi, Ali Shafaghat

    Published 2013-01-01
    “…As their biological activities have an impact on human health, they serve as target molecules in the development of new drugs. The objective of this research was to study the antioxidant activity and chemical analysis of the luteoline from Centaurea behen L. …”
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