One-step introduction of the hexafluoroisobutyl group, synthesis of (S)-5,5,5,5',5',5'-hexafluoroleucine, and its incorporation into peptides and proteins by Delamare, Aline, Naulet, Guillaume, Mummadi, Sandeep, Guichard, Gilles, Compain, Guillaume

“…This modification has been overlooked due to the absence of general, simple, and/or efficient synthetic methods for introducing such a group into small molecules, amino acids, peptides, and proteins. In this account, we review our latest contributions to this field, highlighting the development of a general one-step method to incorporate the hexafluoroisobutyl group using a liquid fluorinated reagent. …”
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Synthesis and Evaluation of In Vitro Antibacterial and Antitumor Activities of Novel N,N-Disubstituted Schiff Bases by Heng Luo, Yu-fen Xia, Bao-fei Sun, Li-rong Huang, Xing-hui Wang, Hua-yong Lou, Xu-hui Zhu, Wei-dong Pan, Xiao-dong Zhang

“…We used the reaction between salicylaldehyde and different diamine compounds, including diamine, ethanediamine, and o-phenylenediamine, determining the structure of obtained molecules by nuclear magnetic resonance spectroscopy and electrospray ionization mass spectroscopy. …”
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A tandem approach for the synthesis of 1-phenyl-pyrazolo-quinolinones by Fe3O4@MWCNT nanocomposite as heterogeneous catalyst by Adapaka Venkateswara Rao, Suresh Maddila, Nagaraju Kerru, Sreekantha B. Jonnalagadda

“…All the synthesized target molecules were characterized and confirmed by various spectroscopic techniques such as 1H-NMR, 15N-NMR, 13C-NMR, and HRMS. …”
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Characterization of Binary Organogels Based on Some Azobenzene Compounds and Alkyloxybenzoic Acids with Different Chain Lengths by Yongmei Hu, Qingshan Li, Wei Hong, Tifeng Jiao, Guangzhong Xing, Qilong Jiang

“…Morphological characterization showed that these gelator molecules have the tendency to self-assemble into various aggregates from lamella, wrinkle, and belt to dot with change of solvents and gelator mixtures. …”
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The Effect of Nitrogen and Phosphorus Limitations at Different Salt Ratios on Growth and Biochemical Composition of Tetraselmis suecica (Chlorodendrophyceae) by Cananur Sisalan Pihava, Leyla Uslu

“…Algae are plant organisms that produce organic molecules in the aquatic environment and absorb carbon. …”
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Comparative mitogenome analysis of two ectomycorrhizal fungi (Paxillus) reveals gene rearrangement, intron dynamics, and phylogeny of basidiomycetes by Qiang Li, Yuanhang Ren, Dabing Xiang, Xiaodong Shi, Jianglin Zhao, Lianxin Peng, Gang Zhao

“…The two mitogenomes of Paxillus involutus and P. rubicundulus comprised circular DNA molecules, with the size of 39,109 bp and 41,061 bp, respectively. …”
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Recognition mechanism and sequence optimization of organophosphorus pesticides aptamers for better monitoring contaminations in food by Pengfei Chen, Chaoqiong Hu, Xuan Tao, Zheng Zhou, Lijun Wang, Xiao Yang, Zhenming Che, Xianggui Chen, Yukun Huang

“…Aptamers as a kind of biological recognition element have shown great potential in monitoring and the rapid quantification of organophosphorus pesticides (OPPs). However, molecules of OPPs are structurally similar and original aptamers selected by systematic evolution of ligands by exponential enrichment are usually long-chain bases, which hamper the further application under OPPs-aptamer recognition. …”
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Morinda citrifolia (Noni) Fruit Juice Reduces Inflammatory Cytokines Expression and Contributes to the Maintenance of Intestinal Mucosal Integrity in DSS Experimental Colitis by Beatriz Coutinho de Sousa, Juliana Reis Machado, Marcos Vinicius da Silva, Thiago Alvares da Costa, Javier Emilio Lazo-Chica, Thatiane do Prado Degasperi, Virmondes Rodrigues Junior, Helioswilton Sales-Campos, Elizabeth Uber Bucek, Carlo José Freire Oliveira

“…These results may point to noni fruit as an important source of anti-inflammatory molecules with a great potential to inhibit the progression of inflammatory diseases, such as inflammatory bowel disease.…”
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Evaluation of Early Markers of Nephropathy in Patients with Type 2 Diabetes Mellitus by Pierina De Muro, Antonio Junior Lepedda, Gabriele Nieddu, Michela Idini, Hai Quy Tram Nguyen, Omar Lobina, Pietro Fresu, Marilena Formato

“…These data suggest that the assessed molecules could represent useful markers to detect early renal impairment in patients with T2DM.…”
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Citrate coated iron oxide nanoparticles: Synthesis, characterization, and performance in protein adsorption by Denise Arrozarena Portilla, Arturo A. Velázquez López, Rosalva Mora Escobedo, Hernani Yee Madeira

“…Surface modification of MNPs not only enhances their stability and biocompatibility but also increases affinity with certain molecules, allowing them to be used in protein separation and adsorption processes. …”
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Non-targeted Metabolomic Analysis of Differences in the Composition of Different Rice Varieties for Baijiu Production by LIU Maoke, TIAN Xinhui, LIU Yao, TANG Yuming, QIN Jian, FENG Jun, LIU Chengyuan

“…A total of 4 159 metabolites were detected in both rice samples, mainly including lipids and lipid-like molecules, organoheterocyclic compounds, organic acids and their derivatives. …”
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Application of Hansen solubility parameters in the eutectic mixtures: difference between empirical and semi-empirical models by Cláudio C. Fernandes, Alexandre Paiva, Reza Haghbakhsh, Ana Rita C. Duarte

“…Although these theoretical models are designed and recommended mostly for simple molecules or simple solutions, they are still being used in eutectic systems studies, mainly empirical ones. …”
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Effects of nitrogen vacancy sites of oxynitride support on the catalytic activity for ammonia decomposition by Kazuki Miyashita, Kiya Ogasawara, Masayoshi Miyazaki, Hitoshi Abe, Yasuhiro Niwa, Hideki Kato, Hideo Hosono, Masaaki Kitano

“…Furthermore, NH3 temperature-programmed surface reactions and density functional theory (DFT) calculations revealed that NH3 molecules are preferentially adsorbed on the nitrogen vacancy sites on the support surface rather than on the Ni surface. …”
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Therapeutic Potential of Dietary Phenolic Acids by Venkata Saibabu, Zeeshan Fatima, Luqman Ahmad Khan, Saif Hameed

“…Based on the available information in the literature, it is suggested that use of PAs as drugs is very promising; however more research and clinical trials are necessary before these bioactive molecules can be made for treatment. Finally this review provides greater awareness of the promise that natural PAs hold for use in the disease prevention and therapy.…”
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Broadening horizons: molecular mechanisms and disease implications of endothelial-to-mesenchymal transition by Cheng Qian, Guanglu Dong, Chunmei Yang, Weiwei Zheng, Chongjin Zhong, Qiuhong Shen, Yin Lu, Yang Zhao

“…During EndMT, reduced expression of endothelial adhesion molecules disrupts intercellular adhesion, triggering cytoskeletal reorganization and mesenchymal transition. …”
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Ammonia Diffusion through Nalophan Double Bags: Effect of Concentration Gradient Reduction by Selena Sironi, Lidia Eusebio, Laura Capelli, Emanuela Boiardi, Renato Del Rosso

“…The losses observed for storage conditions and times as allowed by the reference standard for dynamic olfactometry (EN 13725:2003) indicate that odour concentration values due to the presence of small molecules may be significantly underestimated if samples are not analysed immediately after sampling. …”
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Inferring causal protein signalling networks from single‐cell data based on parallel discrete artificial bee colony algorithm by Jinduo Liu, Jihao Zhai, Junzhong Ji

“…However, current BN methods may exhibit high computational complexity and ignore interactions among protein signalling molecules from different single cells. A novel BN method is presented for learning causal protein signalling networks based on parallel discrete artificial bee colony (PDABC), named PDABC. …”
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Structure Diversity and Properties of Some Bola-like Natural Products by Valentin A. Stonik, Tatyana N. Makarieva, Larisa K. Shubina, Alla G. Guzii, Natalia V. Ivanchina

“…In their shapes, molecules of some bipolar metabolites resemble the so-called bola, a hunting weapon of the South American inhabitants, consisting of two heavy balls connected to each other by a long flexible cord. …”
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Cationic Polymers Inhibit the Conductance of Lysenin Channels by Daniel Fologea, Eric Krueger, Steve Rossland, Sheenah Bryant, Wylie Foss, Tyler Clark

“…The lysenin channels exhibit unique regulation capabilities, which open unexplored possibilities to control the transport of ions and molecules through artificial and natural lipid membranes. …”
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MOX Nanosensors to Detect Colorectal Cancer Relapses from Patient’s Blood at Three Years Follow-Up, and Gender Correlation by Michele Astolfi, Giulia Zonta, Cesare Malagù, Gabriele Anania, Giorgio Rispoli

“…To this aim, a device equipped with nanostructured gas sensors has been employed to detect the airborne molecules of blood samples collected from healthy subjects, and from colorectal cancer affected patients at different stages of their pre- and post-surgery therapeutic path. …”
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