Microanalysis of Organic Pigments in Ancient Textiles by Surface-Enhanced Raman Scattering on Agar Gel Matrices by Marilena Ricci, Cristiana Lofrumento, Emilio Castellucci, Maurizio Becucci

“…This analytical method has been found to be extremely safe for the analyzed substrates, thus being a promising procedure for the selective analysis and detection of molecules at low concentration in the field of artworks conservation.…”
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A modular approach to catalytic stereoselective synthesis of chiral 1,2-diols and 1,3-diols by Sheng Xu, Yuanyuan Ping, Yinyan Su, Haoyun Guo, Aowei Luo, Wangqing Kong

“…The late-stage functionalization of biological active compounds and the expedient synthesis of chiral ligands and pharmaceutically relevant molecules further highlight the synthetic potential of this protocol.…”
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Innovative cross-linked electrospun PVA/MOF nanocomposites for removal of cefixime antibiotic by Razieh Mirzaei, Shahram Tangestaninejad, Afsaneh Marandi, Majid Moghadam, Iraj Mohammadpoor-Baltork, Reihaneh Kardanpour, Hossein Abdolvand

“…ZIF-67 and HKUST contribute to the high adsorption efficiency of the composites by providing a porous structure with high surface area, facilitating interactions with CFX molecules, and enhancing the overall stability of the composite material in the removal process. …”
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CircRNAs as Possible Potential Biomarkers for Breast Cancer Prognosis and Chemotherapy Response: A Comprehensive Study by Saba Mirzaei, Mahdieh Salimi, Hossein Mozdarani

“…Recently, circular RNAs (circRNAs), as closed-loop RNA molecules generated through reverse splicing, have emerged as promising biomarkers for cancer development.  …”
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Beyond gluten-free diet: a critical perspective on phase 2 trials on non-dietary pharmacological therapies for coeliac disease by Davide Scalvini, Chiara Scarcella, Giulia Mantica, Erica Bartolotta, Stiliano Maimaris, Erica Fazzino, Federico Biagi, Federico Biagi, Annalisa Schiepatti, Annalisa Schiepatti

“…The identification of new pathogenetic targets in the last years has enabled the development of several candidates molecules, many of which have been investigated in phase 2/3 clinical trials. …”
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Comparative Analysis of miRNA Expression Profiles of Yak Milk-Derived Exosomes at Different Altitudes by Wenwen Ren, Yongfu La, Xiaoming Ma, Xiaoyun Wu, Xian Guo, Min Chu, Ping Yan, Xianyong Lan, Chunnian Liang

“…Milk-derived exosomes, tiny vesicles containing various biological molecules, play crucial roles in numerous pathological and physiological processes, including cell growth, development, and immune regulation. …”
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Photofunctional Co-Cr Alloy Generating Reactive Oxygen Species for Photodynamic Applications by Kang-Kyun Wang, Bong-Jin Kim, Mi Hee Lee, Byeong-Ju Kwon, Dong Hoon Choi, Jong-Chul Park, Yong-Rok Kim

“…The results suggest that the immobilized photosensitizer molecules on the surface of Co-Cr alloy plate still possess their optical and functional properties including reactive oxygen generation. …”
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Analysis of the Spatial-Frequency Characteristics of the Photo-Assisted Method of a Quartz Rough Surface Nano-Polishing by Vasyl Kanevskii, Serhii Kolienov, Valerii Grygoruk, Oleksandr Stelmakh, Hao Zhang

“…The numerical determination of the evanescent field optimal configuration formed near the quartz rough surface in the gaseous medium saturated with chlorine molecules when illuminated from the quartz side has been considered. …”
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Anti-Biofilm Agents to Overcome <i>Pseudomonas aeruginosa</i> Antibiotic Resistance by Marie Hanot, Elodie Lohou, Pascal Sonnet

“…This review aims to highlight the design strategy and critical features of these molecules to pave the way for further discoveries of highly potent compounds.…”
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The Effects of Activation Energy and Thermophoretic Diffusion of Nanoparticles on Steady Micropolar Fluid along with Brownian Motion by Zulqurnain Sabir, Assad Ayub, Juan L. G. Guirao, Saira Bhatti, Syed Zahir Hussain Shah

“…Thermophoresis is responsible for shifting the molecules within the fluid, and due to this, an increment in boundary layer thickness is found, so by a greater value of Nt, the concentration profile decreases and temperature profile goes down.…”
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Comparative In Vitro Immune Stimulation Analysis of Primary Human B Cells and B Cell Lines by Kristien Van Belle, Jean Herman, Louis Boon, Mark Waer, Ben Sprangers, Thierry Louat

“…Primary polyclonal human B cells underwent in vitro stimulation and their proliferation, production of immunoglobulins (Igs) and of cytokines, and expression of cell surface molecules were analysed using various stimuli. ODN2006, a toll-like receptor 9 (TLR9) agonist, was the most potent general B cell stimulus. …”
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A Multidisciplinary Investigation to Determine the Structure and Source of Dimeric Impurities in AMG 517 Drug Substance by Maria Victoria Silva Elipe, Zhixin Jessica Tan, Michael Ronk, Tracy Bostick

“…Analysis of data from initial LC-MS experiments indicated the presence of two dimer-like molecules. One impurity had an additional sulfur atom incorporated into its structure relative to the other impurity. …”
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Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR by Aixin Yu, Yiqi Wang, Chao Duan, Jun Qin, Miaomiao Liao, Haiyan Zhu, Junrong Lei, Jun Liu, Zehao Yang, Li Yu, Hui Gui, Jinxin Xin, Weiwei Tao, Wendai Bao, Zhiqiang Dong

“…The protein partners and downstream molecules were investigated by RNA-pulldown, mass spectrometry and RNA-seq. …”
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Mechanism of Inflammation in Age-Related Macular Degeneration by Francesco Parmeggiani, Mario R. Romano, Ciro Costagliola, Francesco Semeraro, Carlo Incorvaia, Sergio D’Angelo, Paolo Perri, Paolo De Palma, Katia De Nadai, Adolfo Sebastiani

“…Experimental and clinical evidences strongly indicate the pathogenetic role of immunologic processes in AMD occurrence, consisting of production of inflammatory related molecules, recruitment of macrophages, complement activation, microglial activation and accumulation within those structures that compose an essential area of the retina known as macula lutea. …”
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Simultaneous Determination of Caffeine and Chlorogenic Acids in Green Coffee by UV/Vis Spectroscopy by G. Navarra, M. Moschetti, V. Guarrasi, M. R. Mangione, V. Militello, M. Leone

“…The molar extinction coefficients for caffeine and chlorogenic acid in ethanol solution at 70% were calculated by using the chemical standards; the estimated values were ε(272 nm)=12159±97 M−1 cm−1 for caffeine and ε(330 nm)=27025±190 M−1 cm−1 for chlorogenic acids molecules, respectively. The estimate of concentration values was in agreement with the one obtained by High Performance Liquid Chromatography quantification. …”
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Metal‐based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy by Sunil Kumar, Monu Kumar Shukla, Abhishek Kumar Sharma, Gururaj K. Jayaprakash, Rajiv K. Tonk, Dinesh K. Chellappan, Sachin Kumar Singh, Kamal Dua, Faheem Ahmed, Sanjib Bhattacharyya, Deepak Kumar

“…Several of NMs can also be used for photothermal therapy to destroy cancer cells or enhance immune response to cancer by delivering immune‐stimulating molecules to immune cells or modulating the tumor microenvironment. …”
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Molecular Mechanisms of Phthalate-Induced Hepatic Injury and Amelioration by Plant-Based Principles by Lalit Kumar Singh, Rashmi Pandey, Nikhat Jamal Siddiqi, Bechan Sharma

“…The strategies to combat phthalate-induced toxicity include avoiding exposure to these compounds and using plant-based bioactive molecules such as polyphenols, which possess therapeutic potential as antioxidants, suppress inflammatory cascades, prevent oxidative damage, and stabilize cellular integrity. …”
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Genome Stability Pathways in Head and Neck Cancers by Glenn Jenkins, Kenneth J. O'Byrne, Benedict Panizza, Derek J. Richard

“…Targeted inhibition of signalling receptors has proven to be a clinically-validated therapy, and protein expression of other DNA repair and signalling molecules associated with cancer behaviour could potentially provide a more refined clinical model for prognosis and treatment prediction. …”
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Handling Imbalance Classification Virtual Screening Big Data Using Machine Learning Algorithms by Sahar K. Hussin, Salah M. Abdelmageid, Adel Alkhalil, Yasser M. Omar, Mahmoud I. Marie, Rabie A. Ramadan

“…It enables the discovery of molecules that bind to a specific protein to form a drug. …”
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Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity by Dwaine F. Emerich, Jeffrey H. Kordower, Yaping Chu, Chris Thanos, Briannan Bintz, Giovanna Paolone, Lars U. Wahlberg

“…Delivery of neurotrophic molecules such as GDNF using encapsulated cells has reached a technological point where clinical evaluation is justified. …”
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