Adenosine Inhibits the Release of Arachidonic Acid in Activated Human Peripheral Mononuclear Cells. A Proposed Model for Physiologic and Pathologic Regulation in Systemic Lupus Ery... by Sándor Sipka

“…In the current work, the pathways are presented and reviewed showing how adenosine acts on the production and release of arachidonic acid (AA) in activated human monocytes by the involvement of various phospholipase A2 (PLA2) and protein kinase C (PKC) enzymes in physiological (normal) conditions and in a pathologic state in systemic lupus erythematosus (SLE). Two molecules of activated monocytes mainly determine the actual amounts of AA released: (1) interleukin-1β (IL-1β) increasing and (2) adenosine (Ado) suppressing this process. …”
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Removal of Chromium from Aqueous Solution Using Modified Pomegranate Peel:Mechanistic and Thermodynamic Studies by Tariq S. Najim, Suhad A. Yassin

“…∆S˚ values showed that the process is accompanied by increase in disorder and randomness at the solid solution interface due to the reorientation of water molecules and Cr(VI) ions around the adsorbent surface. …”
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Usefulness of the Vitreous Fluid Analysis in the Translational Research of Diabetic Retinopathy by Olga Simó-Servat, Cristina Hernández, Rafael Simó

“…In this paper we will focus on the vitreous fluid as a tool for exploring the mediators of DR and in particular the molecules related to inflammatory pathways. In addition, their role in the pathogenesis of DR will be discussed. …”
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Gene regulation and signaling transduction in mediating the self-renewal, differentiation, and apoptosis of spermatogonial stem cells by Cai-Mei He, Dong Zhang, Zuping He

“…Significant achievement has recently been made in demonstrating the signaling molecules and pathways mediating the fate decisions of mammalian SSCs. …”
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Features of water crystallization by V. Yu. Stetsenko

“…The peculiarities of water crystallization can be explained on the basis of its nanostructural structure and nanostructural crystallization. Atmospheric air molecules dissolve well in water and are adsorbed by its nanocrystals. …”
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Effect of Counterion on the Solvatochromic Properties of Heteroleptic Chelate Copper(II) Complexes by Hamid Golchoubian, Hakimeh Fazilati

“…To explore the mechanism of interaction between solvent molecules and the complexes, different solvent parameters such as DN, AN, α, ET(30), π*, and β using stepwise multiple linear regression (SMLR) method were employed. …”
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The Influence of the Chemistry of an Organosilica Surface on the Adsorption of Proteins from Water—Salt Solutions by T.I. Denisova, G.F. Karpenko, T.A. Khalyavka, D.I. Shvetz

“…It has been shown that the principal surface chemical features of the organosilica which influence the adsorption of protein molecules on its surface are the ratio of alternating hydrophilic and hydrophobic groups present, the ampholitic character of the silanol groups, the pH value of the point of zero charge (pzc), the pH of the medium, the concentration of the modifying reagent (Cu π ion) employed, the contact time and the solid/liquid phase ratio of the system. …”
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Molecular profiling and detection methods of microRNA in cancer research by Nurul-Syakima Ab Mutalib, Imilia Ismail, Hooi-Leng Ser

“…Years after that, researchers then realized that these miRNAs are actually important regulatory molecules — controlling cell division signaling, apoptosis and so on. …”
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Apparent Molecular Weight Distributions for Investigating Aging in Polymer-Modified Bitumen by Miriam Cappello, Sara Filippi, Yvong Hung, Massimo Losa, Giovanni Polacco

“…Polymer degradation significantly damages the elastomeric network, yet the residual polymer chains still interact with the bitumen molecules and reduce their oxidative aging. The apparent molecular weight distributions were deconvoluted to create an aging index specifically developed for polymer-modified bitumen.…”
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Transcriptional Regulators of Claudins in Epithelial Tight Junctions by Niamat Khan, Abdul R. Asif

“…Intercellular junctions, among epithelial cells, such as desmosomes, adherens, gap, and tight junctions (TJs), not only provide mechanical integrity but also limit movement of molecules across the monolayer. TJ is a complex structure composed of approximately 35 different proteins that interact with each other at the apical side of two adjacent epithelial cells. …”
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Probiotic Bacteria Influence the Composition and Function of the Intestinal Microbiota by Paul W. O'Toole, Jakki C. Cooney

“…Mechanistic insights should be provided by metabolomics and other analytical techniques for small molecules. Rigorous characterization of interactions between the diet, microbiota, and probiotic bacteria will provide new opportunities for modulating the microbiota towards improving human health.…”
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Effect of Functional Groups and pH on the Affinity and Adsorption Capacity of Activated Carbon: Comparison of Homogeneous and Binary Langmuir Model Parameters by Sirous Nouri

“…The influence of pH must be considered in terms of its combined effect on the carbon surface and on the solute molecules. It was confirmed that the uptake of the molecular forms of the aromatic solutes was dependent on the substituents attached to the aromatic ring. …”
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Platinum Nanoparticles Loaded on Activated Carbon as Novel Adsorbent for the Removal of Congo Red by M. Ghaedi, S. J. Hossaini, S. Ramezani

“…The estimated values of enthalpy and entropy both show the positive sign, which indicate that the adsorption process is endothermic and the dye molecules are organized on the adsorbent surface in more randomly fashion than in solution. …”
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Pouchitis unveiled: exploring clinical features, diagnosis, and cutting-edge treatments by Francesca Lusetti, Camilla Almeida Martins Helfenberger, Munique Kurtz de Mello, Natália Sousa Freitas Queiroz

“…Currently, there is still no consensus on the optimal management for CP, though recent progress in understanding the pathophysiology of pouchitis has paved the way for innovative therapeutic approaches, based on biological therapies and small molecules. This review aims to discuss the recent advanced therapies available for pouchitis and provide a comprehensive review on the topic to guide physicians in their clinical practice.…”
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Microbiota and metabolic dysfunction associated with steatotic liver disease by Q. Zhu, S. Francque, W. Kwanten

“…The gut and liver interact bidirectionally through multiple molecules and products, such as nutrients, microbial antigens, metabolites, and bile acids (BAs), which affect both metabolism and immunity, thus controlling both gastrointestinal and liver health and disease. …”
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The Role of Sialic Acid-Binding Receptors (Siglecs) in the Immunomodulatory Effects of Trypanosoma cruzi Sialoglycoproteins on the Protective Immunity of the Host by Alexandre Morrot

“…Most of the immunomodulatory mechanisms associated with this parasitic infection have been attributed to mucin-like molecules on the T. cruzi surface. Mucins are high molecular weight glycoproteins that are involved in regulating diverse cellular activities in both normal and pathological conditions. …”
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Pearson's Hard-Soft Acid-Base Principle as a Means of Interpreting the Reactivity of Carbon Materials by M. Wiśniewski, P.A. Gauden

“…To test the reactivity of adsorption sites as probe molecules, we have used the chloride anion (Cl − ), cation (Cl + ) and radical (Cl 0 ), respectively. …”
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miRNAomic Approach to Plant Nitrogen Starvation by Peerzada Yasir Yousuf, Peerzada Arshid Shabir, Khalid Rehman Hakeem

“…One of the important and recently discovered groups of regulatory molecules acting at the posttranscriptional and translational levels are microRNAs (miRNAs). miRNAs are known to play critical roles in the regulation of gene expression in plants under different stress conditions including N stress. …”
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Environment, Leptin Sensitivity, and Hypothalamic Plasticity by Marco Mainardi, Tommaso Pizzorusso, Margherita Maffei

“…Use of these protocols can, in turn, be exploited to isolate key molecules with translational potential. In the present review, we summarize present knowledge about the mechanisms of plasticity induced by the environment in the ARC. …”
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Machine learning approaches for predicting protein-ligand binding sites from sequence data by Orhun Vural, Leon Jololian

“…These sites enable proteins to bind with other molecules, facilitating key biological functions. Accurate prediction of these binding sites is pivotal in computational drug discovery, helping to identify therapeutic targets and facilitate treatment development. …”
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