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  1. 3201

    Role of MicroRNA in Governing Synaptic Plasticity by Yuqin Ye, Hongyu Xu, Xinhong Su, Xiaosheng He

    Published 2016-01-01
    “…Although synaptic plasticity in neural circuits is orchestrated by an ocean of genes, molecules, and proteins, the underlying mechanisms remain poorly understood. …”
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  2. 3202

    Age-Related Macular Degeneration: Insights into Inflammatory Genes by Raffaella Cascella, Michele Ragazzo, Claudia Strafella, Filippo Missiroli, Paola Borgiani, Francesco Angelucci, Luigi Tonino Marsella, Andrea Cusumano, Giuseppe Novelli, Federico Ricci, Emiliano Giardina

    Published 2014-01-01
    “…Several genetic and molecular studies have indicated the participation of inflammatory molecules (cytokines and chemokines), immune cells (macrophages), and complement proteins in the development and progression of the disease. …”
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  3. 3203

    Pathological Role of Tonsillar B Cells in IgA Nephropathy by Yusuke Suzuki, Hitoshi Suzuki, Junichiro Nakata, Daisuke Sato, Tadahiro Kajiyama, Tomonari Watanabe, Yasuhiko Tomino

    Published 2011-01-01
    “…It is now widely accepted that abnormally glycosylated IgA1 and its related immune complex (IC) are probably key molecules for the pathogenesis, and are thus considered possible noninvasive biomarkers for this disease. …”
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  4. 3204

    CO- and H2S-adsorbed one-dimensional AlSi structures for gas sensing applications by Hoang Van Ngoc

    Published 2025-01-01
    “…This study investigates the properties of one-dimensional AlSi monolayers, specifically AlSi nanoribbons, and their adsorption behaviour with CO and H2S molecules. The electronic, magnetic and optical properties of these systems are calculated using density functional theory and the Vienna Ab initio Simulation Package. …”
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  5. 3205

    Biological therapy for inflammatory bowel disease: cyclical rather than lifelong treatment? by Christian Philipp Selinger, Konstantina Rosiou, Marco V Lenti

    Published 2024-06-01
    “…There are now multiple biologics and increasingly novel small molecules licensed for the treatment of IBD. Treatment guidelines highlight the need for effective control of inflammation and early escalation to advanced therapies to avoid long-term complications. …”
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  6. 3206

    Possible Involvement of Smad Signaling Pathways in Induction of Odontoblastic Properties in KN-3 Cells by Bone Morphogenetic Protein-2: A Growth Factor to Induce Dentin Regenerati... by Ayako Washio, Chiaki Kitamura, Takahiko Morotomi, Masamichi Terashita, Tatsuji Nishihara

    Published 2012-01-01
    “…After treatment with BMP-2, the cell morphology, growth, alkaline phosphatase (ALP) activity, and the activation and expression of BMP-induced intracellular signaling molecules, such as Smad1/5/8 and Smad6/7, as well as activities of dentin sialoprotein (DSP) and dentin matrix protein 1 (DMP1), were examined. …”
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  7. 3207

    Molecular mechanism of aberrant decidualization in adenomyosis leading to reduced endometrial receptivity by Yuanquan Dai, Zheng Yuan, Weisen Fan, Zhiheng Lin

    Published 2025-01-01
    “…Correcting the abnormal expression of molecules in endometrial stromal cells in the endometrium of patients with adenomyosis may become the focus of research to improve endometrial receptivity and increase the pregnancy rate.…”
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  8. 3208

    The Role of Noncoding RNA in Airway Allergic Diseases through Regulation of T Cell Subsets by Shenghao Cheng, Qingping Tang, Shaobing Xie, Sihui Wen, Hua Zhang, Zhihai Xie, Weihong Jiang

    Published 2022-01-01
    “…Noncoding RNAs (ncRNAs) are a class of transcribed RNA molecules that cannot be translated into polypeptides and consist of three major categories, microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs). …”
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  9. 3209

    Toxicological Review of Anticancer Plants Used in Traditional Medicine in Morocco by Soufiane Drioua, Abha Cherkani-Hassani, Otman El-Guourrami, Mouna Ameggouz, Ahmed Zahidi, Abdelhakim Bouyahaya, Sayyed Ibrahim Shah, Yaser Mohammed Al-Worafi, Long Chiau Ming, Hanane Benzaied, Anass Doukkali

    Published 2023-05-01
    “…Further research may be able to explore and discover the potential therapeutic effects of these plants' bioactive molecules with antioxidant and anticancer properties. …”
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  10. 3210

    Platelets tune fear memory in mice by Stefano Garofalo, Alessandro Mormino, Letizia Mazzarella, Germana Cocozza, Arianna Rinaldi, Erika Di Pietro, Maria Amalia Di Castro, Eleonora De Felice, Laura Maggi, Giuseppina Chece, Diego Andolina, Rossella Ventura, Donald Ielpo, Roberto Piacentini, Myriam Catalano, Lucia Stefanini, Cristina Limatola

    Published 2025-02-01
    “…Summary: Several lines of evidence have shown that platelet-derived factors are key molecules in brain-body communication in pathological conditions. …”
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  11. 3211

    Calculation of Free Energy Consumption in Gene Transcription with Complex Promoter Structure by Lifang Huang, Peijiang Liu, Kunwen Wen, Jianshe Yu

    Published 2020-01-01
    “…On the other hand, regulatory molecules present on the core promoter of a gene interact often in a dynamic, highly combinatorial, and possibly energy-dependent manner, leading to a complex promoter structure. …”
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  12. 3212

    Improvement of Landfill Leachate Biodegradability with Ultrasonic Process by Mahvi Amirhossein, Roodbari Aliakbar, Nabizadeh Nodehi Ramin, Naseri Simin, Dehghani Mohammadhadii, Alimohammadi Mahmood

    Published 2012-01-01
    “…Leachate from mature landfills is typically characterized by high ammonium (NH4+) content, low biodegradability (low BOD5/COD ratio) and high fraction of refractory and large organic molecules such as humic and fulvic acids. Mature leachate effluents are known to contain recalcitrant and/or non-biodegradable organic substances and biological processes are not efficient in these cases. …”
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  13. 3213

    A tunable multi-resonance 2D V-groove metasurface by Zhengqing Qi, Yipin Chen, Tianjing Zhao, Peng Chen, Huizhen Yang

    Published 2025-01-01
    “…The inclined plane serves as a “trap” and ensures the target molecules fall into the “hot line.” Theoretically, the EF of SERS can reach up to 5.12 × 1011, surpassing that of traditional nanoparticle antennas. …”
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  14. 3214

    Involvement of Nitric Oxide in a Rat Model of Carrageenin-Induced Pleurisy by Masahiro Iwata, Shigeyuki Suzuki, Yuji Asai, Takayuki Inoue, Kenji Takagi

    Published 2010-01-01
    “…L-arginine and NOC-18 reversed the proinflammatory effects of NO synthase inhibitors, perhaps by reducing the expression of adhesion molecules on endothelial cells. Thus, our results indicate that NO is involved in blunting—not enhancing—the inflammatory response.…”
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  15. 3215

    Supramolecular Biopolymers for Tissue Engineering by Rosario Pérez-Pedroza, Alan Ávila-Ramírez, Zainab Khan, Manola Moretti, Charlotte A. E. Hauser

    Published 2021-01-01
    “…These characteristics are vital for the further development of current trends in TE, such as the use of pluripotent cells for organoid generation, cell-free scaffolds for tissue regeneration, patient-derived organ models, and controlled delivery systems of small molecules. In this review, we will analyse the 3 subtypes of SBPs: peptide-, nucleic acid-, and oligosaccharide-derived. …”
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  16. 3216

    Crystal structure and Hirshfeld surface analysis of 2-methylquinazolin-4(3H)-one hydrochloride by Muzaffar Davlatboev, Sevara Allabergenova, Fazliddin Zulpanov, Ubaydullo Yakubov, Akmaljon Tojiboev, Tulkinjon Sattarov

    Published 2025-02-01
    “…Except for two methyl H atoms, all atoms of the molecular cation are located about a mirror plane, making the quinazolinium moiety exactly planar. Individual molecules are arranged in (001) layers in the crystal. …”
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  17. 3217

    A Theoretical Study on the Influence of the Functional Group Electronic Effect on the Electron Mobility of Cross-Linked Polyethylene by Yang Du, Hui Zhang, Xia Du, Yan Shang, Xuan Wang, Qingguo Chen, Zesheng Li

    Published 2025-01-01
    “…The results show that the electron mobility of grafting nitrobenzene (Ebnb) to polyethylene is the smallest among the studied molecules. As the ability of electron-donating groups increases, the electron mobility gradually increases, while the addition of the electron-withdrawing group reduces the electron mobility and the electron mobility gradually increases with increasing temperature. …”
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  18. 3218

    Photocatalytic Degradation and Hydrogen Production of TiO2/Carbon Fiber Composite Using Bast as a Carbon Fiber Source by Guomei Tang, Asim Abas, Shanpeng Wang

    Published 2018-01-01
    “…The results indicate that 90% RhB molecules could be attacked in 60 min under UV light irradiation, and the hydrogen production rate of water splitting is up to 338.51 μmol/h. …”
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  19. 3219

    The tetracycline resistome is shaped by selection for specific resistance mechanisms by each antibiotic generation by Kevin S. Blake, Yao-Peng Xue, Vincent J. Gillespie, Skye R. S. Fishbein, Niraj H. Tolia, Timothy A. Wencewicz, Gautam Dantas

    Published 2025-02-01
    “…Abstract The history of clinical resistance to tetracycline antibiotics is characterized by cycles whereby the deployment of a new generation of drug molecules is quickly followed by the discovery of a new mechanism of resistance. …”
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  20. 3220

    Intestinal Permeability Assays: a Review by A. A. Iakupova, S. R. Abdulkhakov, R. K. Zalyalov, A. G. Safin, R. A. Abdulkhakov

    Published 2021-04-01
    “…The intestinal barrier integrity and permeability assays differ by the application setting (in vivo or ex vivo), subject (human or animal), marker molecules used to assess permeability (ions, various size carbohydrates, macromolecules, antigens, bacterial products and bacteria), biomaterial for the marker concentration assays (peripheral blood, portal venous blood, urine, stool). …”
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