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  1. 3121

    WASTEWATER TREATMENT OF PIGMENT PRODUCTION PLANTS IN TWO STAGES: PREPARED ACTIVATED CARBON AND ELECTRODIALYSIS PROCESS by Mohammed Q. Gubari, Bilal S. Taha

    Published 2023-07-01
    “…Pigments are available in a wide range of colors, consisting of small molecules practically insoluble in the medium and known to be unique compounds for many industries. …”
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    Article
  2. 3122

    Human Endogenous Retroviruses and Their Putative Role in Pathogenesis of Alzheimer’s Disease, Inflammation, and Senescence by Patrycja Kozubek, Julia Kuźniar, Magdalena Czaja, Hanna Sitka, Urszula Kochman, Jerzy Leszek

    Published 2024-12-01
    “…They have been shown to affect carcinogenesis by modifying the expression of host genes through their functions as enhancers and promoters. Additionally, some molecules derived from HERVs may stimulate the immune system. …”
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    Article
  3. 3123

    Sulfurous Gases As Biological Messengers and Toxins: Comparative Genetics of Their Metabolism in Model Organisms by Neal D. Mathew, David I. Schlipalius, Paul R. Ebert

    Published 2011-01-01
    “…Gasotransmitters are biologically produced gaseous signalling molecules. As gases with potent biological activities, they are toxic as air pollutants, and the sulfurous compounds are used as fumigants. …”
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  4. 3124

    Study on the Utilization of Catechins from Gambir (Uncaria Gambir Roxb) Leaves as Antioxidants Cooking Oil by Daimon Syukri, Fauzan Azima, Rivan Aprialdho

    Published 2023-09-01
    “… Catechins are flavonoid molecules that act as antioxidants in the body. The degradation of palm oil with catechin treatment (400, 200, 100, 50, 0) was investigated in this work (ppm). …”
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    Article
  5. 3125

    Endothelial Progenitor Cell Migration-Enhancing Factors in the Secretome of Placental-Derived Mesenchymal Stem Cells by Witchayaporn Kamprom, Pakpoom Kheolamai, Yaowalak U-Pratya, Aungkura Supokawej, Methichit Wattanapanitch, Chuti Laowtammathron, Sittiruk Roytrakul, Surapol Issaragrisil

    Published 2016-01-01
    “…We recommend that the strategy developed in our study could be used to systematically identify therapeutically useful molecules in the secretomes of other MSC sources for the clinical applications.…”
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    Article
  6. 3126

    Nutrigenomic Functions of PPARs in Obesogenic Environments by Soonkyu Chung, Young Jun Kim, Soo Jin Yang, Yunkyoung Lee, Myoungsook Lee

    Published 2016-01-01
    “…Next, we discuss the interactions of dietary bioactive molecules, such as fatty acids and phytochemicals, with PPARs for the modulation of PPAR-dependent transcriptional activities and metabolic consequences. …”
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    Article
  7. 3127

    Role of Mitogen-Activated Protein Kinase Pathways in Multifactorial Adverse Cardiac Remodeling Associated with Metabolic Syndrome by Mohamed Asrih, François Mach, Alessio Nencioni, Franco Dallegri, Alessandra Quercioli, Fabrizio Montecucco

    Published 2013-01-01
    “…This pathological remodeling has been described to result from the cardiac adaptive response to clinical mechanical conditions (such as hypertension, dyslipidemia, and hyperglycemia), soluble inflammatory molecules (such as cytokines and chemokines), as well as hormones (such as insulin), characterizing the pathophysiology of metabolic syndrome. …”
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  8. 3128

    Synthesis of Some Pyrimidine, Pyrazole, and Pyridine Derivatives and Their Reactivity Descriptors by Nour E. A. Abd El-Sattar, Eman H. K. Badawy, M. S. A. Abdel-Mottaleb

    Published 2018-01-01
    “…Reactivity indices and electrostatic surface potential maps (ESP maps) allow us to establish trends that enable making predictions about chemical characteristics of the newly synthesized molecules and their proton transfer tautomers. Proton transfer is generally more favored in solution than in the gas phase. …”
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  9. 3129

    The Inhibitory Role of B7-H4 in Antitumor Immunity: Association with Cancer Progression and Survival by Changjun He, Haiquan Qiao, Hongchi Jiang, Xueying Sun

    Published 2011-01-01
    “…B7-H4 is one of the most recently identified members of B7 superfamily of costimulatory molecules serving as an inhibitory modulator of T-cell response. …”
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    Article
  10. 3130

    Cytokine Reduction in the Treatment of Joint Conditions by J. D. Sipe, J. Martel-Pelletier, I. G. Otterness, J.-P. Pelletier

    Published 1994-01-01
    “…Potential agents for cytokine reduction include selective anti-cytokine antibodies, anticytokine receptor antibodies, cytokine receptor antagonist proteins, and soluble and chimeric cytokine receptor molecules. Pharmacologic regulation of IL-1 and TNFα remain primary targets for treatment of arthritis, and results of early clinical trials are promising. …”
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    Article
  11. 3131

    Study on the Utilization of Catechins from Gambir (Uncaria Gambir Roxb) Leaves as Antioxidants Cooking Oil by Daimon Syukri, Fauzan Azima, Rivan Aprialdho

    Published 2023-09-01
    “… Catechins are flavonoid molecules that act as antioxidants in the body. The degradation of palm oil with catechin treatment (400, 200, 100, 50, 0) was investigated in this work (ppm). …”
    Get full text
    Article
  12. 3132

    Toll-Like Receptor-Based Strategies for Cancer Immunotherapy by Saghar Pahlavanneshan, Ali Sayadmanesh, Hamidreza Ebrahimiyan, Mohsen Basiri

    Published 2021-01-01
    “…There are plenty of data on the pharmacological targeting of TLR signaling using agonist molecules that boost the antitumor immune response. …”
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    Article
  13. 3133

    Metabolic stability and its role in the discovery of new chemical entities by Słoczyńska Karolina, Gunia-Krzyżak Agnieszka, Koczurkiewicz Paulina, Wójcik-Pszczoła Katarzyna, Żelaszczyk Dorota, Popiół Justyna, Pękala Elżbieta

    Published 2019-09-01
    “…One of the main challenges of medicinal chemistry is not only to design compounds demonstrating beneficial activity, but also molecules exhibiting favourable pharmacokinetic parameters. …”
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    Article
  14. 3134

    Bacterial Exopolysaccharides: From Production to Functional Features by Chouhra Talbi, Salma Elmarrkechy, Mourad Youssfi, Sarah Bouzroud, Meryem Belfquih, Aicha Sifou, Nezha Bouhaddou, Bouabid Badaoui, Abdelaali Balahbib, Abdelhakim Bouyahya, Ilhame Bourais

    Published 2023-11-01
    “…The review also unravels the main extraction, purification, and identification techniques and highlights the key functional features of these complex molecules. …”
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    Article
  15. 3135

    The Strong Inhibition of Pancreatic Lipase by Selected Indonesian Medicinal Plants as Anti-Obesity Agents by Min Rahminiwati, Dyah Iswantini, Trivadila, Rut Novalia Rahmawati Sianipar, Rani Melati Sukma, Susi Indariani, Anggia Murni

    Published 2025-01-01
    “…Pancreatic lipase, an enzyme responsible for converting 50–70% of dietary fat into monoglycerides, free fatty acids, and various other smaller molecules, plays a crucial role in fat metabolism. …”
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  16. 3136

    A 2D cell segmentation protocol for monitoring multiple STAT signaling pathways by fluorescence microscopy by Gergő Szanda, Éva Wisniewski, László Barna, Gábor Turu, Ken Mackie

    Published 2025-03-01
    “…The protocol can be adapted to other signaling molecules undergoing nucleo-cytoplasmic shuttling and to high-throughput applications.This protocol enables simultaneous monitoring of two STAT isoforms using only conventional techniques and equipment and improves upon the assay published in Szanda et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
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  17. 3137

    Two Faces of Protein Kinase Cδ: The Contrasting Roles of PKCδ in Cell Survival and Cell Death by Alakananda Basu, Deepanwita Pal

    Published 2010-01-01
    “…The function of PKCδ depends on various factors, including its localization, tyrosine phosphorylation, and the presence of other pro- and antiapoptoic signaling molecules. This review discusses the current literature on the contrasting roles of PKCδ in cell survival and cell death.…”
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  18. 3138

    A Thermodynamics Study on the Tetrahydrofuran Effect in Exfoliated Graphite Nanoplatelets and Activated Carbon Mixtures at Temperatures between 293.15 and 308.15 K by Florinela Sirbu, Alina Catrinel Ion, Luiza Capra, Ion Ion

    Published 2018-01-01
    “…The identified possible molecular interactions between the edges and the surface of exfoliated graphite nanoplatelets and tetrahydrofuran molecules, which include modifications in the structure of exfoliated nanostructured materials in tetrahydrofuran solvent and the influence of the temperature, and of the solute concentration have been calculated based on the obtained experimental values.…”
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  19. 3139

    Ni(II), Cu(II), Mn(II), and Fe(II) Metal Complexes Containing 1,3-Bis(diphenylphosphino)propane and Pyridine Derivative: Synthesis, Characterization, and Antimicrobial Activity by Maged S. Al-Fakeh, Gadah A. Allazzam, Naeema H. Yarkandi

    Published 2021-01-01
    “…Four of the coordination compounds of the general formula, [M(DPPP)(APY)(H2O) Cl2].xH2O, where M = Ni(II), Cu(II), Mn(II), and Fe(II) and x = 0, 1, or 2 molecules of H2O, DPPP = 1,3-bis(diphenylphosphino)propane, and APY = 2-aminopyridine, have been prepared and characterized. …”
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    Article
  20. 3140

    The natural herbicide rhein targets photosystem I by Alyssa Twitty, Hamlin Barnes, Noa Levy, Yaniv Mizrahi, Yosef Geva, Yael Phillip, Franck E. Dayan

    Published 2024-12-01
    “…Abstract The natural anthraquinone rhein has been identified as a novel herbicide with a potentially new mode of action using a generative AI system for functional molecules discovery. Its herbicidal activity was light-dependent and resulted in rapid burndown symptoms on leaves of treated plants. …”
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