Investigation and Identification of let-7a Related Functional Proteins in Gastric Carcinoma by Proteomics by Yimin Zhu, Xingyuan Xiao, Lairong Dong, Zhiming Liu

“…MicroRNAs are small noncoding RNA molecules that control expression of target genes. …”
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lncRNAs: the unexpected link between protein synthesis and cancer adaptation by Mila Gugnoni, Manoj Kumar Kashyap, Kishore K. Wary, Alessia Ciarrocchi

“…Their capacity to establish multiple and highly dynamic interactions with proteins and other transcripts makes these molecules able to play a central role across all phases of protein synthesis. …”
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Development of a Duplex PCR-NALFIA Assay for the Simultaneous Detection of <i>Macrophomina phaseolina</i> and <i>Verticillium dahliae</i> Causal Agents of Crown and Root Rot of Str... by Viola Papini, Angelo Meloni, Susanna Pecchia

“…In this work, we developed a duplex PCR-NALFIA assay using two pairs of species-specific primers labeled at the 5′ end with different molecules for the simultaneous identification of <i>Mp</i> and <i>Vd</i>. …”
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Discharge and Optical Emission Spectrum Characteristics of a Coaxial Dielectric Barrier Discharge Plasma-Assisted Combustion Actuator by Pengfei Liu, Liming He, Bingbing Zhao

“…In addition, numerous second positive system (SPS) excited nitrogen molecules were detected from the OES signals. The intensity of the spectral lines (297.54 nm, 315.76 nm, 336.96 nm, and 357.56 nm) first increased, then maintained, and then increased rapidly with the increased radius; however, the intensity of the spectral lines (380.34 nm, 405.80 nm, and 434.30 nm) basically remained unchanged, then increased, and finally decreased with the increased radius. …”
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Molecular Signatures of Humic Acids from Different Sources as Revealed by Ultrahigh Resolution Mass Spectrometry by Shuai Qin, Chengbin Xu, Yingzi Xu, Yingchen Bai, Fei Guo

“…Regardless of unsaturation, molecules of River HA have a homogeneous molecular mass distribution and contain many plant-derived lignin- and tannin-like compounds, which are more stable than lipid and more labile than condensed aromatics. …”
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Combinations of TLR Ligands: A Promising Approach in Cancer Immunotherapy by Saskia Stier, Claudia Maletzki, Ulrike Klier, Michael Linnebacher

“…Toll-like receptors (TLRs), a family of pattern recognition receptors recognizing molecules expressed by pathogens, are typically expressed by immune cells. …”
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TopoQual polishes circular consensus sequencing data and accurately predicts quality scores by Minindu Weerakoon, Sangjin Lee, Emily Mitchell, Haynes Heaton

“…This is achieved by sequencing circularized DNA molecules multiple times and combining them into a consensus sequence. …”
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Crystal Chemistry and Structural Complexity of the Uranyl Vanadate Minerals and Synthetic Compounds by Ivan V. Kuporev, Sophia A. Kalashnikova, Vladislav V. Gurzhiy

“…This tendency similarly works for organic molecules, which are incorporated into the uranyl vanadate frameworks. …”
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Jamblang (Syzygium cumini) leaf extract decreased hydrogen peroxide in lead acetate-induced rats by Rauza Sukma Rita, Elmatris Sy, Endrinaldi

“… Background: Free radicals are atoms or molecules with one or more unpaired electrons. Lead acetate has been reported to increase the presence of free radicals in the body. …”
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Molecular Structure and Electronic Properties of Porphyrin-Thiophene-Perylene Using Quantum Chemical Calculation by Tatiya Chokbunpiam, Patchanita Thamyongkit, Oraphan Saengsawang, Supot Hannongbua

“…The structural and electronic properties of the molecules, and the effects of mono- and di-substituents R on C3 and R′ on C4 of the thiophene ring were investigated using a quantum calculation approach. …”
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Fitting and comparison of calcium-calmodulin kinetic schemes to a common data set using non-linear mixed effects modelling. by Domas Linkevicius, Angus Chadwick, Guido C Faas, Melanie I Stefan, David C Sterratt

“…We conclude that more attention should be given to validation and comparison of models of individual molecules.…”
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Borassus aethiopum (Mart.) ethanol fruit extract reverses alloxan-treatment alterations in experimental animals by Moses Dele, Adams, Ejike, Daniel Eze

“…While alloxan substantially (p < 0.05) increased the levels of some biological molecules and enzyme activity, it lowered those of others. …”
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Investigation of metabolic features of glioblastoma tissue and the peritumoral environment using targeted metabolomics screening by LC-MS/MS and gene network analysis by N. V. Basov, A. V. Adamovskaya, A. D. Rogachev, E. V. Gaisler, P. S. Demenkov, T. V. Ivanisenko, A. S. Venzel, S. V. Mishinov, V. V. Stupak, S. V. Cheresiz, O. S. Oleshko, E. A. Butikova, A. E. Osechkova, Yu. S. Sotnikova, Y. V. Patrushev, A. S. Pozdnyakov, I. N. Lavrik, V. A. Ivanisenko, A. G. Pokrovsky

“…Pathway analysis using the KEGG database, conducted with MetaboAnalyst 6.0, revealed a statistically sig­nificant overrepresentation of sphingolipid metabolism, suggesting a critical role of these lipid molecules in glio­blastoma pathogenesis. Using computational systems biology and artificial intelligence methods implemented in a cognitive platform, ANDSystem, molecular genetic regulatory pathways were reconstructed to describe potential mechanisms underlying the dysfunction of sphingolipid metabolism enzymes. …”
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The Expression Pattern and Functional Analysis of Extracellular Vesicle Long Non-Coding RNAs from Uterine Fluid During Implantation in Pig by Yijun Shang, Qiuping Zhang, Yue Ding, Yongzhong Wang, Shengchen Gu, Xupeng Zang, Zheng Xu, Sixiu Huang, Zicong Li, Zhenfang Wu, Ting Gu, Linjun Hong, Gengyuan Cai

“…Extracellular vesicles (EVs) in the uterine fluid (UF) can target and deliver maternal endometrial signalling molecules to embryonic trophoblast cells, exerting crucial regulatory effects during embryo implantation. …”
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Surface topography modulates initial platelet adhesion to titanium substrata by Cecilia Yan Guo, Raymond Mo, Hugh Kim

“…In addition, the secretion of critical molecules stored in platelet granules (platelet factor 4, PF4; soluble P-selectin, sCD62P; transforming growth factor-beta1, TGF-β1; platelet-derived growth factor-AB, PDGF-AB) was measured by enzyme-linked immunosorbent assay (ELISA) analysis of the supernatants. …”
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Inhibitory Effects of iPSC-MSCs and Their Extracellular Vesicles on the Onset of Sialadenitis in a Mouse Model of Sjögren’s Syndrome by Bo Hai, Taeko Shigemoto-Kuroda, Qingguo Zhao, Ryang Hwa Lee, Fei Liu

“…Extracellular vesicles (EVs) carry bioactive molecules in the same way as their originating cells and are more stable and considered much safer than cells for therapies. …”
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The role of lipids and lipids lowering drugs in human papillomavirus (HPV) and HPV-associated cancers by Ehsan Shabani, Aida Hasanzadi, Omer Qutaiba B. Allela, Radhwan Abdul Kareem, Riyad E. Abed, Ali M. Ali Al-Nuaimi, Zainab H. Athab, Shiva Khodarahmi

“…One of the most noticeable metabolic abnormalities in cancer is lipid metabolism reprogramming, in which cancer cells dysregulate lipid metabolism to obtain sufficient energy, building blocks for cell membranes, and signaling molecules necessary for invasion, metastasis, proliferation, and survival. …”
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Effects of Chinese Liquors on Cardiovascular Disease Risk Factors in Healthy Young Humans by Ju-Sheng Zheng, Jing Yang, Tao Huang, Xiao-Jie Hu, Ming Luo, Duo Li

“…Serum uric acid (P=0.004 for TFL, P=0.001 for TCL), glucose (P<0.001 for TFL, P<0.001 for TCL) and endothelial adhesion molecules (P<0.05) were significantly decreased after the intervention. …”
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Cell signaling communication within papillary craniopharyngioma revealed by an integrated analysis of single-cell RNA sequencing and bulk RNA sequencing by Xiaoyue Zhu, Yanfei Jia, Zicheng Zhao, Xiaoyu Zhang, Yunlong Zhao, Songbai Gui, Xiu-An Yang

“…Conclusion Through analyzing the communication of essential signaling pathways, ligands, and receptors among epithelial cells, fibroblasts, and neutrophils in PCP tumor tissues, we have identified certain molecules with promising prognostic and therapeutic potential.…”
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Tunning valence state of cobalt centers in Cu/Co-CoO1-x for significantly boosting water-gas shift reaction by Xing-Chi Li, Jun-Hao Wang, Tao-Tao Huang, Yang Hu, Xin Li, De-Jiu Wang, Wei-Wei Wang, Kai Xu, Chun-Jiang Jia, Hao Dong, Guangshe Li, Chen Li, Ya-Wen Zhang

“…Abstract Dual active sites with synergistic valence state regulation under oxidizing and reducing conditions are essential for catalytic reactions with step-wise mechanisms to modulate the complex adsorption sites of reactant molecules on the surfaces of heterogeneous catalysts with maximized catalytic performances, but it has been rarely explored. …”
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