A stumbling block in pancreatic cancer treatment: drug resistance signaling networks by Jinming Liu, Biao Zhang, Bingqian Huang, Kexin Zhang, Fujia Guo, Zhizhou Wang, Dong Shang, Dong Shang

“…The primary node molecules in the cell signaling network in cancer tissues are maladjusted and mutated in comparison to normal tissues, which promotes the occurrence and progression of cancer. …”
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Serum Levels of Soluble IL-2R, CD4 and CD8 in Chronic Active HCV Positive Hepatitis by C. Caruso, G. Candore, D. Cigna, S. Tripi, G. Di Gaetano, G. Migneco, G. Montalto, I. Ruggieri, A. Notarbartolo

“…No correlations were found for both sIL-2R and sCD8 and these two molecules with other parameters of liver function. …”
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Neutrophil adhesion to vessel walls impairs pulmonary circulation in COVID-19 pathology by Hiroshi Ueki, I-Hsuan Wang, Maki Kiso, Kenta Horie, Shun Iida, Sohtaro Mine, Michiko Ujie, Hung-Wei Hsu, Chen-Hui Henry Wu, Masaki Imai, Tadaki Suzuki, Wataru Kamitani, Eiryo Kawakami, Yoshihiro Kawaoka

“…In the lungs of SARS-CoV-2-infected mice, increased expression of adhesion molecules in intravascular neutrophils prolonged adhesion time to the vessel wall, resulting in platelet aggregation and impaired lung perfusion. …”
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Adipose Tissue-Derived Extracellular Vesicles: A Promising Biomarker and Therapeutic Strategy for Metabolic Disorders by Wenhui Liu, Tianyan Liu, Qingyu Zhao, Junqiu Ma, Jiajia Jiang, Hui Shi

“…Extracellular vesicles (EVs) are recognized as novel medium for remote intercellular communication by transferring various bioactive molecules from parental cells to distant target cells. …”
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Recent Advances in Underlying Pathologies Provide Insight into Interleukin-8 Expression-Mediated Inflammation and Angiogenesis by Basit Saleem Qazi, Kai Tang, Asma Qazi

“…Several cell types express the receptor for the cytokine IL-8 and upon its recognition produce molecules that are active both locally and systemically. …”
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Synthesis of Kojic Ester Derivatives as Potential Antibacterial Agent by Carolynne Zie Wei Sie, Zainab Ngaini, Nurashikin Suhaili, Eswaran Madiahlagan

“…The presence of C=C and N=N reactive moieties in both chalcone and azo molecules contributed to the potential biological activities of the kojic acid ester.…”
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Investigation on Microstructure of Potassium Nitrate/Sodium Nitrate Composites for Solar Storage System by Qianjun Mao, Ning Liu, Li Peng, Hongjun Wu

“…., the composition of the material elements of the atomic structure, the molecular structure, and atoms or molecules in space arrangement and the aggregation characteristics. …”
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Angiogenesis in Spontaneous Tumors and Implications for Comparative Tumor Biology by C. Benazzi, A. Al-Dissi, C. H. Chau, W. D. Figg, G. Sarli, J. T. de Oliveira, F. Gärtner

“…Angiogenesis is a prognostic indicator for a variety of tumors, and it coincides with increased shedding of neoplastic cells into the circulation and metastasis. Several molecules such as cell surface receptors, growth factors, and enzymes are involved in this process. …”
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DFT and TD-DFT Study of Structure and Properties of Semiconductive Hybrid Networks Formed by Bismuth Halides and Different Polycyclic Aromatic Ligands by Y. Belhocine, M. Bencharif

“…The structure and spectroscopic properties of polycyclic aromatic ligands of 2,3,6,7,10,11-hexakis (alkylthio) triphenylene (alkyl: methyl, ethyl, and isopropyl; corresponding to the abbreviations of the molecules: HMTT, HETT and HiPTT) were studied using density functional theory (DFT) and time dependent density functional theory (TD-DFT) methods with triple-zeta valence polarization (TZVP) basis set. …”
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The potential role of nanobodies in asthma therapy by Baraa Khalid Salah Al-Sheakly, Fatemeh Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Narjes Saheb Sharif-Askari, Narjes Saheb Sharif-Askari, Jennifer E. Hundt, Rabih Halwani, Rabih Halwani

“…The pathophysiology of asthma involves a complex interplay of immune cells and mediators, including cytokines, chemokines, and other inflammatory molecules. Despite advances in asthma management, many patients continue to experience symptoms due to the limitations of current therapies. …”
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Phytosomes – an Effective Drug-Delivery System. Development, Technology, Application. by I.A. Khabarov, S.D. Sergazy, A.S. Maikenova, A.N. Zhabayeva, O.V. Maslova, S.M. Adekenov

“…A review of various studies on the production and application of phytosomal medical forms, which are in the form of hybrid molecules with high solubility in lipid and aqueous environments, is presented in this article. …”
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Exploring the Ruthenium-Ligands Bond and Their Relative Properties at Different Computational Methods by Adebayo A. Adeniyi, Peter A. Ajibade

“…It is observed that optimization of molecules of many light atoms with different functional methods results in significant geometrical variation in the values and order of the computed properties. …”
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Screening hepatoprotective effective components of Lonicerae japonica Flos based on the spectrum-effect relationship and its mechanism exploring by Song Wang, Lin Yang, Ajiao Hou, Songtao Liu, Liu Yang, Haixue Kuang, Hai Jiang

“…Molecular docking is used to explore the interaction between small molecules and proteins. This work provided a general model of the combination of UPLC-PDA and hepatoprotective effect to study the spectrum-effect relationship of LF, which can be used to considerable methods and insight for the fundamental research of the material basis of similar healthcare food.…”
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Role of Zinc Signaling in the Regulation of Mast Cell-, Basophil-, and T Cell-Mediated Allergic Responses by Keigo Nishida, Ryota Uchida

“…The intracellular zinc signaling regulates immune reactions. Although many molecules involved in these processes have zinc-binding motifs, the molecular mechanisms and the role of zinc in immune responses have not been elucidated. …”
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Characterization of extracellular vesicles by capillary zone electrophoresis: A novel concept for characterization of a next-generation drug delivery platform by Aleksandra Steć, Andrea Heinz, Szymon Dziomba

“…Their ability to penetrate biological barriers and to transfer molecules between cells shows their potential as a novel class of drug delivery platform. …”
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Strong toxic gas detection on penta-BCP monolayers: Insights from DFT calculations by Thanasee Thanasarnsurapong, Suchanuch Sringamprom, Pakpoom Reunchan, Weekit Sirisaksoontorn, Sirichok Jungthawan, Piyanooch Nedkun, Jariyanee Prasongkit, Adisak Boonchun

“…Penta-BCP exhibits strong and selective interactions with specific toxic gas molecules, including CO, NO, and NO2. This results in the remarkable ability to readily capture these harmful gases while demonstrating minimal interaction with non-toxic counterparts such as H2, N2, CO2, and CH4, underlining its exceptional selectivity. …”
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Axon Guidance Mechanisms for Establishment of Callosal Connections by Mitsuaki Nishikimi, Koji Oishi, Kazunori Nakajima

“…Midline populations express and secrete guidance molecules, and “pioneer” axons as well as interactions between the medial and lateral axons are also involved in the axon pathfinding of the callosal neurons. …”
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WHEAT ANTIMICROBIAL PEPTIDES by T. I. Odintsova, T. V. Korostyleva, L. L. Utkina, Ya. A. Andreev, A. A. Slavokhotova, E. A. Istomina, V. A. Pukhal’skii, T. A. Egorov

“…Most of them belong to cysteine-rich peptides; their molecules contain even numbers of cysteine residues involved in the formation of disulphide bonds, which stabilize the peptide structure. …”
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SELF-ASSEMBLY OF NANOSCALE POLYMER DOMAINS IN MICROSTRUCTURE TEMPLATE MADE BY AFM MICROMACHINING TECHNIQUE by ZOU XinYu, HUANG YiJun, CONG YanRu, HE YongLing, PAN YuChen, MIAO ZhiBin

“…Furthermore,pairing bottom-up and top-down methods is a bright,and perhaps basic,bridge between the parallel self-assembly of molecules and the morphological constraint of prevailing technology.…”
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Inflammatory Mechanisms of Organ Crosstalk during Ischemic Acute Kidney Injury by Laura E. White, Heitham T. Hassoun

“…Evidence from preclinical models cites mechanisms of organ crosstalk during ischemic AKI including the expression of cellular adhesion molecules, lymphocyte trafficking, release of proinflammatory cytokines and chemokines, and modification of the host innate and adaptive immune response systems. …”
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