Serum Oxidative Stress-related Biomarkers in Ocular Hypertension and Glaucoma by Mine Esen Baris, Onur Furundaoturan, Meltem Kocamanoğlu, Seray Sahin, Yasemin Akçay, Suzan Güven Yılmaz

“… Purpose: To evaluate the serum levels of oxidative stress-related molecules in patients with ocular hypertension (OHT) and primary open-angle glaucoma (POAG) compared with healthy controls. …”
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Nano-MIP based SPR sensor for tetracycline analysis in milk sample by Monireh Bakhshpour-Yücel, Melike Küçük, Elif Tümay Özer, Bilgen Osman

“…The relationship between Tc molecules and the SPR sensor was analyzed at 0.5–20 mg/L Tc concentrations (pH 5.0). …”
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Extracellular Cold-Inducible RNA-Binding Protein and Hemorrhagic Shock: Mechanisms and Therapeutics by Naureen Rashid, Zhijian Hu, Asha Jacob, Ping Wang

“…Hypoxia and hypoperfusion lead to the release of molecules that act as danger signals known as damage-associated molecular patterns (DAMPs). …”
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Mature tertiary lymphoid structure associated CD103+ CD8+ Trm cells determined improved anti-tumor immune in breast cancer by Qin Fang, Shuru Chen, Xiaoyue Chen, Wei Zou, Di Chen, Yukang Huang, Chucheng Wu

“…Furthermore, the secretion function of effector molecules by CD8+ CD103+ Trm cells and NK cells within TLSs was significantly enhanced, indicating a strong correlation between the effector function of CD103+ CD8+ Trm and NK cells and the maturity of TLSs.ConclusionOur study identifies potential additional prognostic information for the clinical prognosis of breast cancer patients, underscoring the prognostic significance of immune cells within TLS, with a particular focus on CD103+ CD8+ Trm cells and NK cells.…”
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Investigation of biometabolites and novel antimicrobial peptides derived from promising source Cordyceps militaris and effect of non-small cell lung cancer genes computationally. by Muhammad Afzal, Mai Abdel Haleem A Abusalah, Neelum Shehzadi, Muhammad Absar, Naveed Ahmed, Sarmir Khan, Yalnaz Naseem, Noshaba Mehmood, Kirnpal Kaur Banga Singh

“…Computational analysis on non-small cell lung cancer genes (NSCLC) was performed on quantified compounds to interpret the biometabolites from C. militaris that could be potential drug candidate molecules with high specificity and potency. A total of 34 compounds representing 100% of total detected constituents identified were identified using GCMS analysis and 20 compounds using LC-MS which showed strong biological activities. …”
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Synthesis and Characterization of Bioactive Acylpyrazolone Sulfanilamides and Their Transition Metal Complexes: Single Crystal Structure of 4-Benzoyl-3-methyl-1-phenyl-2-pyrazolin-... by Omoruyi G. Idemudia, Alexander P. Sadimenko, Anthony J. Afolayan, Eric C. Hosten

“…On the basis of elemental analysis, spectroscopic and TGA results, transition metal complexes, with octahedral geometry having two molecules of the bidentate keto-imine ligand each, have been proposed. …”
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Development of a novel, high-throughput imaged capillary isoelectric focusing-Western method to characterize charge heterogeneity of monoclonal antibody heavy and light chains by Gangadhar Dhulipala, Alanna Broszeit, Kun Lu, Nisha Palackal, Erica Pyles

“…It can impact the stability, efficacy, and safety of products, but it can also affect the pharmacokinetics, binding affinity, and overall biological activity of the molecules. Given the substantial size and complexity of antibodies, subtle variations or specific modifications that result in charge heterogeneity might be concealed when mAbs are analyzed under native conditions. …”
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The impact of KRAS mutations on the tumour microenvironment and treatment response in non-small cell lung cancer by Guomin Gu, Chunling Liu, Yan Yang, Yan Zhao, Xiaodan Zhu, Gang Sun

“…A total of 1323 DEGs were predominantly enriched in the PI3K-Akt signalling pathway, cell adhesion molecules, and metabolism of xenobiotics by cytochrome P450. …”
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Multiscale Physics of Atomic Nuclei from First Principles by Z. H. Sun, A. Ekström, C. Forssén, G. Hagen, G. R. Jansen, T. Papenbrock

“…The techniques developed in this work clarify how microscopic nuclear forces generate the multiscale physics of nuclei spanning collective phenomena as well as short-range correlations and allow one to capture emergent and dynamical phenomena in finite fermion systems such as atom clusters, molecules, and atomic nuclei.…”
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Cu-Ag/SBA-15 nano catalysts for the control of microorganisms in water by Saidulu Ganji, Ramesh Kola, Kumaraswamy Gullapelli, Ramesh Martha

“…Abstract Because of their uniform and regular channels, adjustable pore size, large surface area, controllable wall composition, high hydrothermal stability, ease of functional modification, and good accessibility of larger reactant molecules, mesoporous siliceous SBA-15 is of excellent catalyst carrier that is highly versatile and has been used extensively to prepare a variety of supported catalysts with ideal catalytic properties. …”
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A Review on the Role of Human Solute Carriers Transporters in Cancer by Md. Shafiul Hossen, Mohammed Shafin Ul Islam, Mohammad Yasin, Mohammed Ibrahim, Abhijit Das

“…As solute carriers (SLC) transporters are capable of transporting different amino acids, cancer may develop as a result of these transporters' over‐expression due to their complex formation with other biological molecules. Therefore, this review investigated the role of SLC transporters in the progression of cancer. …”
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Nitroxyl protects H9C2 cells from H/R-induced damage and inhibits autophagy via PI3K/Akt/mTOR pathway. by Li Li, Zhixin Wang, Yaxuan Lyu, Yanqing Guo

“…HNO also inhibited autophagy and regulated expressions of key autophagy-related molecules, including LC3II, p62 and Beclin1. Further experiments demonstrated that the effects of HNO were mediated through upregulation of PI3K/Akt/mTOR pathway. …”
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Etoricoxib–NLC Mitigates Radiation-Induced Ovarian Damage in Rats: Insights into Pro-Inflammatory Cytokines, Antioxidant Activity, and Hormonal Responses by Sahar Khateeb

“…Histopathological evaluations and oxidative stress biomarker assessments were conducted, including ELISAs for reactive oxygen species (ROS), pro-inflammatory cytokines (IL-1β, TNF-α), and signaling molecules (PI3K, AKT, P38MAPK, AMH). Serum levels of estrogen, FSH, and LH were measured, and gene expression analysis for <i>TGF-β</i> and <i>Nrf2</i> was performed using qRT-PCR. …”
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A Phage‐Based Approach to Identify Antivirulence Inhibitors of Bacterial Type IV Pili by Tori M. Shimozono, Nancy J. Vogelaar, Megan T. O'Hara, Zhaomin Yang

“…Antivirulants are small molecules designed to target virulence factors, thereby attenuating the virulence of infectious microbes. …”
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Synthesis, In Silico, and Biological Applications of Novel Heteroleptic Copper (II) Complex of Natural Product-Based Semicarbazone Ligands by Fekadu Muleta, Tegene Desalegn

“…Furthermore, the docking result of prepared compounds on S. aureus gyrase confirms the ligands (L1 and L2) and the complex potential molecules possess the smallest binding potential of −8.0 to −8.4 kcal/mol. …”
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DICER1: The Argonaute Endonuclease Family Member and Its Role in Pediatric and Youth Pathology by Consolato M. Sergi, Fabrizio Minervini

“…It has been determined that the function of RNase III proteins is set to identify and degrade double-stranded molecules of RNA. <i>DICER1</i> is a vital “housekeeping” gene. …”
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Drought Tolerance in Modern and Wild Wheat by Hikmet Budak, Melda Kantar, Kuaybe Yucebilgili Kurtoglu

“…Therefore, identification of candidate molecules or loci involved in drought tolerance is necessary, which is undertaken by “omics” studies and QTL mapping. …”
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Water Clustering in Wheat Flour and Its Role in Water Diffusion: Observation Based on Sorption Isotherm by ZHAO Xuewei, WEI Xiaoxiao, GUO Yu, WANG Hongwei, ZHANG Hua

“…Furthermore, based on thermodynamic factor and self-diffusivity, it was found that water molecules were more likely to interact with themselves, leading to water clustering, which could be the major contributor to the sharp decrease of water diffusivity. …”
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A Study of Serum Adiponectin Levels in Patients with Polycystic Ovarian Syndrome and its Correlation with Various Cardiometabolic Risk Markers by G. Surendra Prasad, Uma Kaimal Saikia, Ashok Krishna Bhuyan, Abhamoni Baro

“…Background: Polycystic ovarian syndrome (PCOS) is the most common metabolic disorder in the reproductive age group, the pathogenesis of which is constantly evolving with the discovery of novel molecules and the lookout for potential therapeutic targets. …”
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Identification of Key Genes and Pathways Associated with Age-Related Macular Degeneration by Junyu Zhang, Yu Zhou

“…As expected, several ophthalmic disease-related molecules, including RHO, PDE6A, 3′,5′-cyclic-GMP phosphodiesterase, and G protein alpha, were in the central nodes of disease network. …”
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