Influence of Drying Methods on the Morphological Features, Microstructural Properties, and Antioxidant Performance of <i>Floccularia luteovirens</i>: A Metabolomic Analysis by Mengjun Xiao, Tao Wang, Chuyu Tang, Min He, Xiaojian Pu, Tingjing Zhao, Yuling Li

“…A correlation analysis indicated a significant link between antioxidant capacity and lipid as well as lipid-like molecules. Metabolomic analysis identified 1617 metabolites across 15 superclasses, with lipids, lipid-like molecules, organic acids and derivatives, and organic heterocyclic compounds being the predominant metabolites in <i>F. luteovirens</i>. …”
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Plasma Levels of Free Fatty Acids in Women with Gestational Diabetes and Its Intrinsic and Extrinsic Determinants: Systematic Review and Meta-Analysis by Jose Rafael Villafan-Bernal, Mariana Acevedo-Alba, Rodrigo Reyes-Pavon, Guillermo Andres Diaz-Parra, Diana Lucia Lip-Sosa, Hilda Imelda Vazquez-Delfin, Martha Hernandez-Muñoz, Daniel Ely Bravo-Aguirre, Francesc Figueras, Raigam Jafet Martinez-Portilla

“…Free fatty acids, also known as nonesterified fatty acids, are proinflammatory molecules that induce insulin resistance in nonpregnant individuals. …”
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Prevention of H-Aggregates Formation in Cy5 Labeled Macromolecules by Jing Kang, Oliver Kaczmarek, Jürgen Liebscher, Lars Dähne

“…H-aggregate formation is caused by an inhomogeneous distribution of the Cy5 molecules on the polymer chain. The H-aggregates can be destroyed by conformational changes of the PAH induced by interactions with polyanions or in organic solvents. …”
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Identification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development by Katharina Weinhäupl, Louis Meuret, Sandy Desrat, Fanny Roussy, Nelly Morellet, Sandra Beaupierre, Catherine Guillou, Carine van Heijenoort, Olga Abian, Sonia Vega, Ian Wolf, Tatos Akopian, Olga Krandor, Eric Rubin, Adrian Velazquez-Campoy, Diego Gauto, Hugo Fraga

“…While the pharmacological properties of these natural product antibiotics prevent their use in the clinic, similar molecules binding to the same binding pockets can result in new drugs against Mtb. …”
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Flavonoid-membrane Interactions: A Protective Role of Flavonoids at the Membrane Surface? by Patricia I. Oteiza, Alejandra G. Erlejman, Sandra V. Verstraeten, Carl L. Keen, César G. Fraga

“…We suggest that interactions of polyphenols at the surface of bilayers through hydrogen bonding, can act to reduce the access of deleterious molecules (i.e. oxidants), thus protecting the structure and function of membranes.…”
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Macrophages in sepsis-induced acute lung injury: exosomal modulation and therapeutic potential by Kaiying Lv, Qun Liang

“…Exosomes, small extracellular vesicles released by various cells, carry bioactive molecules that influence macrophage polarization and immune responses. …”
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Photophysical, Photochemical, and BQ Quenching Properties of Zinc Phthalocyanines with Fused or Interrupted Extended Conjugation by Gülşah Gümrükçü, Gülnur Keser Karaoğlan, Ali Erdoğmuş, Ahmet Gül, Ulvi Avcıata

“…The group effects on peripheral position and the continual and intermittent conjugation of the phthalocyanine molecules on the photophysical and photochemical properties are also investigated. …”
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Reversible Shaping of Microwells by Polarized Light Irradiation by Federica Pirani, Angelo Angelini, Francesca Frascella, Emiliano Descrovi

“…In this work, we propose a polymeric pattern of soft-imprinted microwells containing azobenzene molecules. The shape of individual elements of the pattern can be controlled after fabrication by irradiation with properly polarized light. …”
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tRNA modifications: greasing the wheels of translation and beyond by Minjie Zhang, Zhipeng Lu

“…Both tRNAs and small fragments processed from them play many nonconventional roles in addition to translation. tRNA molecules undergo various types of chemical modifications to ensure the accuracy and efficiency of translation and regulate their diverse functions beyond translation. …”
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Inflammasomes in neurodegenerative diseases by Qianchen Wang, Songwei Yang, Xuan Zhang, Shanshan Zhang, Liping Chen, Wanxue Wang, Naihong Chen, Jiaqing Yan

“…Abstract Inflammasomes represent a crucial component of the innate immune system, which respond to threats by recognizing different molecules. These are known as pathogen-associated molecular patterns (PAMPs) or host-derived damage-associated molecular patterns (DAMPs). …”
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A Review of the Physiological and Immunological Functions of Biliary Epithelial Cells: Targets for Primary Biliary Cirrhosis, Primary Sclerosing Cholangitis and Drug-induced Ductop... by Chih-Te Wu, Paul A. Davis, VelImir A. Luketic, M. Eric Gershwin

“…BEC transports IgA as well as IgM into bile, synthesizes and secretes various chemokines, cytokines, and expresses adhesion molecules involved in cell interaction and signal transduction. …”
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The possible therapeutic role of advanced glycation end-product inhibitors in ischemic stroke by Nada H. Aljarba, Hayder M. Al-Kuraishy, Ali I. Al-Gareeb, Mustafa M. Shokr, Marios Papadakis, Athanasios Alexiou, Mubarak Alruwaili, Mohammed Alrouji, Mohammed S. Alshammari, Gaber El-Saber Batiha

“…The advanced glycation end-products (AGEs) are toxic molecules result from non-enzymatic interactions of sugar with lipids or proteins. …”
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Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: An update since 2020 by Yanqing Liu, Jie Chen, Xiang Li, Yu Fan, Cheng Peng, Xiaochun Ye, Yingshuang Wang, Xin Xie

“…RAS proteins, as pivotal signal transduction molecules, are frequently mutated and hyperactivated in various human cancers, closely associated with tumor cell proliferation, survival, and metastasis. …”
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Thermophysical investigation of glycol ethers in mannitol solutions at various temperatures by Chakraborty Nabaparna, Thakur Priya, Juglan Kailash Chandra, Syed Abrar Hussain

“…Analysis was done on the interactions between the molecules in the ternary mixture of D-mannitol and glycol ethers in aqueous medium.…”
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Structural information in therapeutic peptides: Emerging applications in biomedicine by Valentín Iglesias, Oriol Bárcenas, Carlos Pintado‐Grima, Michał Burdukiewicz, Salvador Ventura

“…This trend stems from their cost‐effectiveness and reduced immunogenicity, compared to antibodies or recombinant proteins, but also from their ability to dock and interfere with large protein–protein interaction surfaces, and their higher specificity and better biocompatibility relative to organic molecules. Many tools have been developed to understand, predict, and engineer peptide function. …”
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Paclitaxel-induced Hypersensitivity Reaction by Cyril Sajan, Elizabeth Jacob, Varunsingh Saggu, Rajesh Hadia, Hemraj Singh Rajput

“…The mechanism of this reaction is not known exactly, but it is believed that the reaction may be occurring due to paclitaxel itself or its vehicle castor oil IP (Cremophor ELP). Molecules present in Cremophor ELP are found to be similar in structure to certain nonionic block copolymers that activate complement proteins (the proteins involved in various immune processes).…”
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Curcumin as a Therapeutic Agent in Dementia: A Mini Systematic Review of Human Studies by Natascia Brondino, Simona Re, Annalisa Boldrini, Antonella Cuccomarino, Niccolò Lanati, Francesco Barale, Pierluigi Politi

“…A growing interest has recently risen on the potential use of natural molecules in this condition. Curcumin is a polyphenolic compound traditionally used in Indian medicine. …”
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Current Perspectives regarding Stem Cell-Based Therapy for Alzheimer’s Disease by Kyeong-Ah Kwak, Seung-Pyo Lee, Jin-Young Yang, Young-Seok Park

“…Many unsuccessful attempts have been made to develop new small molecules or antibodies to intervene in the disease’s pathogenesis. …”
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The Role of Toll-Like Receptor Signaling in the Progression of Heart Failure by Lili Yu, Zhiwei Feng

“…More and more emerging data indicate that TLR signaling pathway molecules are involved in the progression of HF. Herein, we present new data with regard to the activation of TLRs in the failing heart, focusing on TLR2, TLR3, TLR4, and TLR9, and suggest the potential use of TLRs in target therapy.…”
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High order harmonic generation-based attosecond light sources and applications to quantum phenomena by E. Constant, S. Nandi, C. Picot, E. Prost, S. Palakkal, F. Lépine, V. Loriot

“…In this perspective article, we present some of the current developments in high harmonic generation sources, as well as related applications in quantum and attosecond dynamics in atoms and molecules.…”
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