Investigation of Functional Activity of Cells in Granulomatous Inflammatory Lesions from Mice with Latent Tuberculous Infection in the New Ex Vivo Model by Elena Ufimtseva

“…The colocalization of the phagocytic receptors and costimulatory molecules in the surface microdomains of granuloma cells (with and without acid-fast BCG-mycobacteria) has also been detected. …”
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A novel necroptosis-related gene signature predicts the prognosis and immunotherapeutic response in breast cancer through immune infiltration by Dezhi Lu, Sifang Qiu, Zhiqiang Zeng

“…High NecroptosisScore were characterized by elevated expression levels of MHC molecules, stimulated infiltration of immune cells and lengthened survival. …”
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Neuroimmunology of psoriasis: Possible roles for calcitonin gene-related peptide in its pathogenesis by Joshua Kotlyar, Richard D. Granstein

“…This allows it to play a role in a variety of cutaneous inflammatory disorders such as psoriasis, exerting effects on various immune cells via effector molecules such as neuropeptides. In this review, we discuss the role of calcitonin gene-related peptide in modulating the immune system and inflammation, with a focus on psoriasis.…”
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Evaluation of extra virgin olive oil compounds using computational methods: in vitro, ADMET, DFT, molecular docking and human gene network analysis study by Velid Unsal, Reşit Yıldız, Aziz Korkmaz, Başak Doğru Mert, Cemile Gunbegi Calıskan, Erkan Oner

“…KEGG enrichment analysis further linked key molecules like oleuropein and apigenin with pathways related to lipid metabolism and atherosclerosis, underscoring their potential bioactivity and relevance in health-related applications.…”
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Schwann cells in regeneration and cancer by Lan Zhang, Jiale Xie, Wenyu Dai, Bing Lu, Sheng Yi

“…Transplantation of Schwann cells and/or Schwann cell-derived molecules also serves as a helpful approach for the treatment of other injured tissues, such as the spinal cord, skin, digit tip, and bone. …”
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Synthesis, Crystal Structures, and DNA Binding Properties of Zinc(II) Complexes with 3-Pyridine Aldoxime by Konstantis F. Konidaris, Rigini Papi, Eugenia Katsoulakou, Catherine P. Raptopoulou, Dimitrios A. Kyriakidis, Evy Manessi-Zoupa

“…The ZnII ion is five-coordinated, surrounded by four oxygen atoms of two acac- moieties and by the pyridyl nitrogen atom of the (3-py)CHNOH ligand. Molecules of 1 interact with the water lattice molecules forming a 2D hydrogen-bonding network. …”
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Altered Phenotype of Circulating Dendritic Cells and Regulatory T Cells from Patients with Acute Myocarditis by Paola del Carmen Guerra-de-Blas, Daniela Cruz-González, Elena B. Martínez-Shio, Roberto González-Amaro, Héctor González-Pacheco, Esther Layseca-Espinosa, Carlos D. Escobedo-Uribe, Adriana E. Monsiváis-Urenda

“…DCs from myocarditis patients showed a higher expression of costimulatory molecules while a diminished expression of the inhibitory receptors, ILT2 and ILT4. …”
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Mesenchymal Stromal Cells Are More Immunosuppressive In Vitro If They Are Derived from Endometriotic Lesions than from Eutopic Endometrium by Fawaz Abomaray, Sebastian Gidlöf, Cecilia Götherström

“…Then, ESC were phenotypically examined for protein and gene expression of immunosuppressive and immunostimulatory molecules. Finally, ESC were functionally examined for their effects on monocyte differentiation into macrophages. …”
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A comprehensive review on multifunctional bioactive properties of elm oyster mushroom Hypsizygus ulmarius (Bull.) Redhead (Agaricomycetes): Current research, challenges and future... by Aditya, Neeraj, J.N. Bhatia, Ajar Nath Yadav

“…Mushrooms have evolved as a nutritional powerhouse, harnessing a diverse spectrum of bioactive molecules to fortify human health. Hypsizygus ulmarius represents a pioneering species within the oyster mushrooms distinguished by its unique characteristics and potential abilities. …”
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Coactivators in PPAR-Regulated Gene Expression by Navin Viswakarma, Yuzhi Jia, Liang Bai, Aurore Vluggens, Jayme Borensztajn, Jianming Xu, Janardan K. Reddy

“…In the nucleus, PPARs exist as heterodimers with retinoid X receptor-α bound to DNA with corepressor molecules. Upon ligand activation, PPARs undergo conformational changes that facilitate the dissociation of corepressor molecules and invoke a spatiotemporally orchestrated recruitment of transcription cofactors including coactivators and coactivator-associated proteins. …”
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Sulfur chains glass formed by fast compression by Kaiyuan Shi, Xiao Dong, Zhisheng Zhao, Lei Su, Cheng Ji, Bing Li, Jiaqing Zhang, Xingbang Dong, Pu Qiao, Xin Zhang, Haotian Yang, Guoqiang Yang, Eugene Gregoryanz, Ho-kwang Mao

“…Abstract Due to the sulfur’s atoms’ propensity to form molecules and/or polymeric chains of various sizes and configuration, elemental sulfur possesses more allotropes and polymorphs than any other element at ambient conditions. …”
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Dissolution and Pharmacokinetic Studies of Paracetamol-4,4′-Bipyridine Cocrystals Obtained Using Four Methods by Xiaoming Zhang, Yejia Huang, Jinliang Li, Yiying Chen, Jialing Lian

“…All featured strong hydrogen bonds formed between the paracetamol,4,4′-bipyridine and water molecules. An additional notable feature is the presence of π...π stacking interactions between the pyridine rings of adjacent 4,4′-bipyridine molecules. …”
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Mitochondrial DNA Structure in <i>Trypanosoma cruzi</i> by Alfonso Herreros-Cabello, Francisco Callejas-Hernández, Manuel Fresno, Núria Gironès

“…This kinetoplast is a network of concatenated circular molecules comprising a maxicircle (20–64 kb) and up to thousands of minicircles varying in size depending on the species (0.5–10 kb). …”
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Engineering amphiphilic alkenyl lipids for self-assembly in functional hybrid nanostructures by Raúl Gimeno-Ferrero, Victoria Valdivia, Inmaculada Fernández, María Luisa García-Martín, Manuel Pernia Leal

“…In this study, we explore the relationship between structure and self-assembly in novel low molecular weight amphiphilic molecules to produce stable and biocompatible hybrid nanostructures. …”
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Muscle-derived extracellular vesicles mediate crosstalk between skeletal muscle and other organs by Jiajie Jia, Jiajie Jia, Lu Wang, Lu Wang, Yue Zhou, Peng Zhang, Xiaoping Chen

“…Skeletal muscle (SKM) has crucial roles in locomotor activity and posture within the body and also functions have been recognized as an actively secretory organ. Numerous bioactive molecules are secreted by SKM and transported by extracellular vesicles (EVs), a novel class of mediators of communication between cells and organs that contain various types of cargo molecules including lipids, proteins and nucleic acids. …”
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Adipokines as Drug Targets in Diabetes and Underlying Disturbances by Vinícius Andrade-Oliveira, Niels O.S. Câmara, Pedro M. Moraes-Vieira

“…Adipokines are pleiotropic molecules that gather factors such as leptin, adiponectin, visfatin, apelin, vaspin, hepcidin, RBP4, and inflammatory cytokines, including TNF and IL-1β, among others. …”
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Binding of CXCL8/IL-8 to Mycobacterium tuberculosis Modulates the Innate Immune Response by Agnieszka Krupa, Marek Fol, Bozena R. Dziadek, Ewa Kepka, Dominika Wojciechowska, Anna Brzostek, Agnieszka Torzewska, Jaroslaw Dziadek, Robert P. Baughman, David Griffith, Anna K. Kurdowska

“…In summary, our data suggest that the association of IL-8 with M. tb molecules may modify and possibly enhance the innate immune response in patients with TB.…”
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Effect of SIS3 on Extracellular Matrix Remodeling and Repair in a Lipopolysaccharide-Induced ARDS Rat Model by Qiong Liang, Qiqing Lin, Yueyong Li, Weigui Luo, Xia Huang, Yujie Jiang, Chunyan Qin, Jin Nong, Xiang Chen, Suren Rao Sooranna, Liao Pinhu

“…Although it is clear that TGF-β1 can modulate the expression of the extracellular matrix (ECM) through intracellular signaling molecules such as Smad3, its role as a therapeutic target against ARDS remains unknown. …”
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Evaluating Medicinal Plants for Anticancer Activity by Elisha Solowey, Michal Lichtenstein, Sarah Sallon, Helena Paavilainen, Elaine Solowey, Haya Lorberboum-Galski

“…Most chemotherapeutic drugs for cancer treatment are molecules identified and isolated from plants or their synthetic derivatives. …”
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Germanyl triazoles as a platform for CuAAC diversification and chemoselective orthogonal cross-coupling by John M. Halford-McGuff, Thomas M. Richardson, Aidan P. McKay, Frederik Peschke, Glenn A. Burley, Allan J. B. Watson

“…The reaction is often high yielding, functional group tolerant, and compatible with complex molecules. The installation of the Ge moiety enables further diversification of the triazole products, including chemoselective transition metal-catalysed cross-coupling reactions using bifunctional boryl/germyl species.…”
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