Visualizing stepwise evolution of carbon hybridization from sp 3 to sp 2 and to sp by Wei Xiong, Guang Zhang, De-Liang Bao, Jianchen Lu, Lei Gao, Yusen Li, Hui Zhang, Zilin Ruan, Zhenliang Hao, Hong-Jun Gao, Long Chen, Jinming Cai

“…Our work expands the scope of carbon hybridization evolution and serves as an advance in flexibly engineering carbon-material by employing cyanomethyl-substituted molecules.…”
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Magnetic Solid-Phase Extraction Based on β-Cyclodextrins/Acrylic Acid Modified Magnetic Gelatin for Determination of Moxidectin in Milk Samples by Yinzhu Shang, Jing Luo, Peng Wang, Xiaoya Zhao, Cheng Ye, Shaofei Guo

“…Due to the rigidity of hydrophobic cavity of β-cyclodextrins and carboxyl groups of acrylic acid, magnetic composites are prepared to form a complex with target molecules through various kinds of chemical reactions and then showed excellent extraction performance. …”
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Predicting immunotherapy efficacy in endometrial cancer: focus on the tumor microenvironment by Liubov A. Tashireva, Irina V. Larionova, Irina V. Larionova, Nikita A. Ermak, Anastasia A. Maltseva, Ekaterina I. Livanos, Anna Yu. Kalinchuk, Marina N. Stakheyeva, Larisa A. Kolomiets

“…The resistance to immunotherapy is multifactorial mechanism, encompassed genetic and epigenetic alterations in tumor cells modulating immune checkpoint molecules, resulted in escaping immune surveillance. …”
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Anticancer Activity of Ferulic Acid-Inorganic Nanohybrids Synthesized via Two Different Hybridization Routes, Reconstruction and Exfoliation-Reassembly by Hyoung-Jun Kim, Kitae Ryu, Joo-Hee Kang, Ae-Jin Choi, Tae-il Kim, Jae-Min Oh

“…Therefore we could conclude that the nanohybrids of ferulic acid and layered double hydroxide had cellular delivery property of intercalated molecules on cancer cell lines.…”
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A New Activated Carbon for CO Capture from Coal-Fired Boiler Flue Gas by J. Don Carruthers, Melissa A. Petruska, Gopala Krishnan, Marc Hornbostel, Jianer Bao

“…With the current environmental interest in controlling greenhouse gases, there is a new focus on materials that can discriminate between gas molecules by capturing those gases that must be curtailed and releasing those that pose no adverse effects to the atmosphere. …”
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An Emerging New Paradigm in Opioid Withdrawal: A Critical Role for Glia-Neuron Signaling in the Periaqueductal Gray by Handong Ouyang, Shue Liu, Weian Zeng, Roy C. Levitt, Keith A. Candiotti, Shuanglin Hao

“…Accumulating evidence suggests that glial activation leading to the release of proinflammatory molecules acting on neurons is important in the complex syndrome of opioid dependence and withdrawal. …”
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Hijacking of the nervous system in cancer: mechanism and therapeutic targets by Yu Zhang, Qili Liao, Xuyang Wen, Jiayan Fan, Tifei Yuan, Xuemei Tong, Renbing Jia, Peiwei Chai, Xianqun Fan

“…Consequently, targeting specific signaling molecules within neuro-oncological regulatory pathways could potentially suppress tumor development. …”
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Immunotherapy of Ovarian Cancer: The Role of Checkpoint Inhibitors by Francesca De Felice, Claudia Marchetti, Innocenza Palaia, Daniela Musio, Ludovico Muzii, Vincenzo Tombolini, Pierluigi Benedetti Panici

“…In this review we will explore the rationale of immunotherapy in ovarian cancer with a special focus on these emerging molecules.…”
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Microcystins Induces Vascular Inflammation in Human Umbilical Vein Endothelial Cells via Activation of NF-κB by Jun Shi, Jie Zhou, Min Zhang

“…Furthermore, MC-LR also increased cell adhesion molecules (ICAM-1 and VCAM-1) expression in HUVECs. …”
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Marine Diterpenoids as Potential Anti-Inflammatory Agents by Yisett González, Daniel Torres-Mendoza, Gillian E. Jones, Patricia L. Fernandez

“…This review is a compilation of marine diterpenoids, mainly isolated from corals, which have been described as potential anti-inflammatory molecules.…”
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Ignition delay prediction for fuels with diverse molecular structures using transfer learning-based neural networks by Mo Yang, Dezhi Zhou

“…A transfer learning framework was subsequently developed, enabling the models trained on smaller molecules (1–3 carbon atoms) to predict ignition delays for larger molecules (4 carbon atoms) with minimal additional data. …”
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Low-Cost and Portable Biosensor Based on Monitoring Impedance Changes in Aptamer-Functionalized Nanoporous Anodized Aluminum Oxide Membrane by Nianyu Jiang, Pranav Shrotriya

“…The biosensor is utilized to detect amodiaquine molecules using an amodiaquine-binding aptamer (OR7)-functionalized membrane. …”
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Potential common targets of music therapy intervention in neuropsychiatric disorders: the prefrontal cortex-hippocampus -amygdala circuit (a review) by Yuqin Dan, Ying Xiong, Danghan Xu, Yuqi Wang, Meng Yin, Pengwei Sun, Yi Ding, Ziyun Feng, Peng Sun, Weili Xia, Gongchang Yu, Gongchang Yu, Li Li, Li Li

“…This may be closely related to the release of signaling molecules such as monoamine neurotransmitters, the glutamatergic system, the gut-microbiota-brain axis, pro-inflammatory cytokines and the endogenous opioid peptide system. …”
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Computational Modeling of the Interaction of Silver Nanoparticles with the Lipid Layer of the Skin by Andrea Fabara, Sebastián Cuesta, Fernanda Pilaquinga, Lorena Meneses

“…Silver nanoparticles seemed to have very good clearance properties in our molecular dynamics simulation because over a certain period of time, the silver cluster got far away from the biological molecules.…”
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Physical Properties, Chemical Structure, and Microstructure of Thermoplastic Polyurethane Recycled Material-Modified Asphalt by Peng Yang, Peiliang Cong, Hongjie Hao, Pengfei Xiong

“…Thermal susceptibility was affected by the degree of swelling and dissolution of the TPRM particles, the composition of the asphalt, and the interface effect between the asphalt molecules and both the regular and slender–irregular TPRM particles. …”
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Regulation of pattern recognition receptor signaling by palmitoylation by Xiaocui Li, Xiaofang Hu, Hongjuan You, Kuiyang Zheng, Renxian Tang, Fanyun Kong

“…Summary: Pattern recognition receptors (PRRs), consisting of Toll-like receptors, RIG-I-like receptors, cytosolic DNA sensors, and NOD-like receptors, sense exogenous pathogenic molecules and endogenous damage signals to maintain physiological homeostasis. …”
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Cryogenic Hydrogen Adsorption onto H-, Li-, Na-Exchanged Zeolites with Various Si/Al Ratios by Masaru Kubo, Yoshihiro Kamimura, Keiji Itabashi, Tatsuya Okubo

“…Zeolites with narrower pore channel (2.6 ∞ 5.7 Å) exhibit higher initial Q st values than zeolites with wide pore channel (7.4 ∞ 7.4 Å), because of the strong dispersion interaction between hydrogen molecules and the surface of the pore channel. Li-exchanged zeolites exhibit high initial Q st values; however, the 6-membered ring zeolite frameworks adsorb less hydrogen at 77 K and 0.1 MPa than Na-exchanged zeolites, because Li cations, unlike larger Na cations, can penetrate the ring, and thus become less accessible to hydrogen molecules. …”
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Synthesis and crystal structures of 4,4′-methylenebis(2,6-diethylaniline) and 4,4′-methylenebis(3-chloro-2,6-diethylaniline) by Daniil E. Smirnov, Oleg S. Morozov, Ekaterina S. Afanasyeva, Viktor V. Avdeev

“…The presence of the chlorine substituent slightly affects the twist angle between the two aromatic components. The molecules of compound 1 form a network structure through intermolecular N—H...N bonds and C—H...π interactions, while in the crystal structure of compound 2, the molecules are assembled solely through N—H...π interactions. …”
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Haemophilus parasuis Subunit Vaccines Based on Native Proteins with Affinity to Porcine Transferrin Prevent the Expression of Proinflammatory Chemokines and Cytokines in Pigs by R. Frandoloso, S. Martínez-Martínez, E. F. Rodríguez-Ferri, S. Yubero, D. Rodríguez-Lázaro, M. Hernández, C. B. Gutiérrez-Martín

“…However, overexpression of all proinflammatory molecules was observed in CHG group, mainly in the target infection tissues (brain, lungs, and spleen). …”
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NLRP3 is a BMI-independent mediator of stable COPD by Yonca Gungor, Selin Ercan, Saliha Selin Özuygur Ermiş, Yiğit Kozalı, Gizem Kursunluoglu, Ceyda Sahan, Aylin Ozgen Alpaydin, Hulya Ayar Kayali

“…The expression levels of NLRP3 inflammasome molecules did not differ in terms of disease severity or BMI. …”
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