The Dependency of Diffusion Coefficients and Geometric Factor on the Size of the Diffusing Molecule: Observations for Different Clay-Based Materials by Elke Jacops, Marc Aertsens, Norbert Maes, Christophe Bruggeman, Rudy Swennen, Bernd Krooss, Alexandra Amann-Hildenbrand, Ralf Littke

“…We observed that, for unreactive gases in clayey materials, the effective diffusion coefficient varies with the size of the diffusing molecule and this variation can be described by an exponential or a power law function. …”
Get full text

Neurotransmitter-bound bestrophin channel structures reveal small molecule drug targeting sites for disease treatment by Aaron P. Owji, Jingyun Dong, Alec Kittredge, Jiali Wang, Yu Zhang, Tingting Yang

“…We further identified multiple small molecules as activators of the bestrophin channels. …”
Get full text

Inflammatory changes in the choroid plexus following subarachnoid hemorrhage: the role of innate immune receptors and inflammatory molecules by Peter Solár, Peter Solár, Václav Brázda, Václav Brázda, Martin Bareš, Alemeh Zamani, Parisa EmamiAref, Andrea Joukal, Lucie Kubíčková, Erik Kročka, Klaudia Hašanová, Marek Joukal

Get full text

On the Dual Role of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) in Human Malignancies by Andreea Calinescu, Gabriela Turcu, Roxana I. Nedelcu, Alice Brinzea, Anastasia Hodorogea, Mihaela Antohe, Carmen Diaconu, Coralia Bleotu, Daniel Pirici, Lucia B. Jilaveanu, Daniela A. Ion, Ioana A. Badarau

“…Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a glycoprotein belonging to the carcinoembryonic antigen (CEA) family that is expressed on a wide variety of cells and holds a complex role in inflammation through its alternate splicing and generation of various isoforms, mediating intricate mechanisms of modulation and dysregulation. …”
Get full text

ACE2 : S1 RBD Interaction-Targeted Peptides and Small Molecules as Potential COVID-19 Therapeutics by Lennox Chitsike, John Krstenansky, Penelope J. Duerksen-Hughes

“…We also assessed the possibility of reprofiling of candidate small molecules that previously have been shown to interfere with the viral entry of SARS-CoV. …”
Get full text

In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration by Georgios Petrogiannakis, Irene Guadagnino, Santiago Negueruela, Martina Di Guida, Elena Marrocco, Mariateresa Pizzo, Annalaura Torella, Mariateresa Zanobio, Marianthi Karali, Diego Luis Medina, Sabrina Carrella, Sandro Banfi

“…We demonstrate that the HCI in vitro assay we devised is a reliable screening method to select candidate molecules for mutation-independent therapeutic approaches for retinal disorders. …”
Get full text

Periradicular Tissue Responses to Biologically Active Molecules or MTA When Applied in Furcal Perforation of Dogs' Teeth by Anna Zairi, Theodoros Lambrianidis, Ourania Pantelidou, Serafim Papadimitriou, Dimitrios Tziafas

“…None of the biologically active molecules can be suggested for repairing furcal perforations, despite the fact that growth factors exerted a clear stimulatory effect on cementum formation and inhibited collagen capsule formation. …”
Get full text

Features of determining the parameters of crystal lattice of ice-like associates of water molecules during hydrate formation by N.A. Shostak

“…Dependences are proposed for calculating the heat of formation of the crystal lattice from ice-like associates of water molecules. It is shown that the process of restructuring the ice lattice into a hydrate lattice can be both exothermic and endothermic. …”
Get full text

Macrocycle Unidirectional Transport Along a Linear Molecule by a Two‐Step Chemical Reaction Sequence by Aldo C. Catalán, Lucio Peña‐Zarate, Ruy Cervantes, Alberto Vela, Jorge Tiburcio

“…Herein we present the functioning of a molecule capable of transporting a cyclic species in a preferential direction. …”
Get full text

Étude comparative de substances bioactives pour la protection des biens patrimoniaux contre les insectes ravageurs by Grazia Nicosia, Fabien Fohrer, Yoanna Dechezleprêtre, Virginia Gisel de Billerbeck

Subjects: Get full text

Bactericidal/Permeability-Increasing Protein (BPI), a Novel Antimicrobial Molecule in Human Breast Milk with Immune Potential by Alba Soledad Aquino-Domínguez, María de los Ángeles Romero-Tlalolini, Honorio Torres-Aguilar, Juan Carlos Rodríguez-Alba, Lucia Lourdes Martínez-Martínez, Francisco Javier Sánchez-Peña, María Teresa Hernández-Huerta, Jesús Elizarrarás-Rivas, Gabriela Tapia-Pastrana, Melisa Gómez-López, Elsa Cruz-Martínez, Uriel Eleazar Hernández-Corrales, Sergio Roberto Aguilar-Ruiz

“…Breast milk is a fluid of vital importance during the first stages of life of the newborn since, in addition to providing nutrients, it also contains cells and molecules of the immune system, which protect the neonate from infection and, at the same time, modulate the establishment of the microbiota. …”
Get full text

Novel Terthiophene-Substituted Fullerene Derivatives as Easily Accessible Acceptor Molecules for Bulk-Heterojunction Polymer Solar Cells by Filippo Nisic, Alessia Colombo, Claudia Dragonetti, Alessandra Cominetti, Andrea Pellegrino, Nicola Perin, Riccardo Po, Alessandra Tacca

Get full text

Bioactive molecules from soybeans (Glycine max) with anti-type 2 diabetes activity: a systematic review by Adekunle Babajide Rowaiye, Lorretha Chinonye Emenyonu, Ezinne Janefrances Nwonu, Okiemute Ajiroghene Okpalefe, Joseph Akwoba Ogugua, Victor Oluwatoyin Akinseye, Gordon Chukwuma Ibeanu

“…This study examined how bioactive molecules from soybeans modulate key enzymes that affect T2D. …”
Get full text

Diffusion and Friction Dynamics of Probe Molecules in Liquid n-Alkane Systems: A Molecular Dynamics Simulation Study by Song Hi Lee

“…As the molecular weight of n-alkane increases, the ratio of Dself/DMY2 becomes less than 1 and the probe molecules encounter, in turn, two different microscopic frictions depending on MMY/Mmatrix and the temperature. …”
Get full text

Spinorphin Molecules as Opportunities for Incorporation into Spinorphin@AuNPs Conjugate Systems for Potential Sustained Targeted Delivery to the Brain by Stela Georgieva, Petar Todorov, Jana Tchekalarova

“…<b>Background:</b> This study explores the potential for the synthesis of peptide nanosystems comprising spinorphin molecules (with rhodamine moiety: Rh-S, Rh-S5, and Rh-S6) conjugated with nanoparticles (AuNPs), specifically peptide Rh-S@AuNPs, peptide Rh-S5@AuNPs, and peptide Rh-S6@AuNPs, alongside a comparative analysis of the biological activities of free and conjugated peptides. …”
Get full text

Tailoring pyridine bridged chalcogen-concave molecules for defects passivation enables efficient and stable perovskite solar cells by Muhammad Azam, Yao Ma, Boxue Zhang, Xiangfeng Shao, Zhongquan Wan, Huaibiao Zeng, Haomiao Yin, Junsheng Luo, Chunyang Jia

“…The uncoordinated Pb2+ and iodine vacancy defects can interact with chalcogen-concave group and pyridine group through the formation of the Lewis acid-base adduct, particularly both the defects can be surrounded by concave molecules, resulting in effective suppression charge recombination. …”
Get full text

Potential inhibition of CXCL12/SDF-1 by small molecule Hesperetin in management of tobacco associated oral cancer by G. Radha, Ramya Ramadoss, Pradeep Kumar Yadalam, Rajeshkumar Shanmugam

“…Discussion: Binding energy score between CXCL12/SDF-1 and small molecule Hesperetin is indicative of a strong and stable interaction, significative of a high affinity for the chemokine. …”
Get full text

Pharmacokinetic and Biodistribution Assessment of a Near Infrared-Labeled PSMA-Specific Small Molecule in Tumor-Bearing Mice by Joy L. Kovar, Lael L. Cheung, Melanie A. Simpson, D. Michael Olive

“…To facilitate preclinical testing of such outcomes, here we developed and characterized a PSMA-targeted small molecule, YC-27. IRDye 800CW was conjugated to YC-27 or an anti-PSMA antibody used for reference. …”
Get full text

Adsorption model of non-additive binary gas mixture on square lattice: attraction between molecules of different types by A. V. Myshlyavtsev, M. D. Myshlyavtseva, V. F. Fefelov

“…We have done complete analysis of the ground-state phase diagram for this model on a square lattice taking into account nearest-neighbor attraction between molecules of different types and arbitrary interactions between one type molecules. …”
Get full text

Caffeine as an Active Molecule in Cosmetic Products for Hair Loss: Its Mechanisms of Action in the Context of Hair Physiology and Pathology by Ewelina Szendzielorz, Radoslaw Spiewak

“…Molecules…”
Get full text