Metabolomics to Identify Unclassified Uremic Toxins: A Comprehensive Literature Review by Raymond Vanholder, Griet Glorieux, Angel Argiles, Stéphane Burtey, Gerald Cohen, Flore Duranton, Laetitia Koppe, Ziad A. Massy, Alberto Ortiz, Rosalinde Masereeuw, Dimitrios Stamatialis, Joachim Jankowski

“…A comprehensive review of known uremic retention molecules goes back to more than 10 years ago and did not consider metabolomic analyses. …”
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Network analysis uncovers the master role of WRKY transcription factors in Arabidopsis thaliana response to N-acyl homoserine lactones by Yongming Duan, Min Han, Maja Grimm, Adam Schikora

“…Abstract Background Plants can perceive bacterial molecules such as the quorum sensing signals N-acyl homoserine lactones (AHL), thus modifying their fitness in response to environmental factors. …”
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Follicular Helper CD4+ T Cells in Human Neuroautoimmune Diseases and Their Animal Models by Xueli Fan, Chenhong Lin, Jinming Han, Xinmei Jiang, Jie Zhu, Tao Jin

“…TFH cells can be identified by a combination of markers, including the chemokine receptor CXCR5, costimulatory molecules ICOS and PD-1, transcription repressor Bcl-6, and cytokine IL-21. …”
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Current Views of Toll-Like Receptor Signaling Pathways by Masahiro Yamamoto, Kiyoshi Takeda

“…Recent studies have demonstrated that Toll-like receptors (TLRs) play crucial roles in innate responses that lead not only to the clearance of pathogens but also to the efficient establishment of acquired immunity by directly detecting molecules from microbes. In terms of intracellular TLR-mediated signaling pathways, cytoplasmic adaptor molecules containing Toll/IL-1R (TIR) domains play important roles in inflammatory immune responses through the production of proinflammatory cytokines, nitric oxide, and type I interferon, and upregulation of costimulatory molecules. …”
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Synthesis and Experimental Validation of New Designed Heterocyclic Compounds with Antiproliferative Activity versus Breast Cancer Cell Lines MCF-7 and MDA-MB-231 by Vincenza Barresi, Carmela Bonaccorso, Domenico A. Cristaldi, Maria N. Modica, Nicolò Musso, Valeria Pittalà, Loredana Salerno, Cosimo G. Fortuna

“…In the present paper, in order to further verify the robustness of this model, we report the results of the projection of more than 150 known molecules and 9 newly synthesized compounds. We predict their activity versus MCF-7 cell line and experimentally verify the in silico results for some promising chosen molecules in two human breast cell lines, MCF-7 and MDA-MB-231.…”
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Biomarkers in Adult Dermatomyositis: Tools to Help the Diagnosis and Predict the Clinical Outcome by Charles Cassius, Hélène Le Buanec, Jean-David Bouaziz, Reyhan Amode

“…This article reviews molecules that could be used as biomarkers for diagnosis and monitoring dermatomyositis disease activity.…”
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Viral Response to Specifically Targeted Antiviral Therapy for Hepatitis C and the Implications for Treatment Success by Curtis L Cooper

“…Regardless, several STAT-C molecules are poised to become the standard of care for HCV treatment in the foreseeable future. …”
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In Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric Disorders by Harry Pantazopoulos, Sabina Berretta

“…Rapidly emerging evidence implicates perineuronal nets (PNNs) and extracellular matrix (ECM) molecules that compose or interact with PNNs, in the pathophysiology of several psychiatric disorders. …”
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Di-tert-butyldiisothiocyanatotin(IV) by Anne Kamrowski, Hans Reuter

“…The title compound, [Sn(C4H9)2(NCS)2], which crystallizes with one and a half molecules in the asymmetric unit, represents a new structure type for intermolecular sulfur...tin interactions, which is characterized by an antiparallel (A) arrangement of the dipole moments of the individual molecules. …”
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CCL-2 and CXCL-8: Potential Prognostic Biomarkers of Acute Kidney Injury after a Bothrops atrox Snakebite by Juliana Costa Ferreira Neves, Hiochelson Najibe Santos Ibiapina, Fábio Magalhães-Gama, Jacqueline Almeida Gonçalves Sachett, Iran Mendonça Silva, Kerolaine Fonseca Coelho, Eliane Campos Alves, Andréa Monteiro Tarragô, Luiz Carlos de Lima Ferreira, Adriana Malheiro, Wuelton Marcelo Monteiro, Allyson Guimarães Costa

“…Here, we characterize the profile of these soluble immunological molecules as possible predictive biomarkers of the development of AKI. …”
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Finding the best column for polar basic analytes across reversed-phase and hydrophilic interaction liquid chromatography by József Simon, Márton Kovács, Pál T. Szabó

“…On the other hand, these types of molecules can behave vastly differently despite their similarities. …”
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Improved protocol for metabolite extraction and identification of respiratory quinones in extremophilic Archaea grown on mineral materials by Sebastian V. Gfellner, Sebastian V. Gfellner, Cyril Colas, Cyril Colas, Cyril Colas, Guillaume Gabant, Guillaume Gabant, Janina Groninga, Martine Cadene, Martine Cadene, Tetyana Milojevic, Tetyana Milojevic

“…Furthermore, we identified molecules involved in microbial interactions, i.e., cell surface interactions through biofilm formation and cell–cell interactions through quorum sensing, which relies on messenger molecules for microbial communication. …”
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Studies of the Accelerating Effect of Thiourea on the Reduction of Zn in Mixed Water–Organic Solvents at the Mercury Electrode by B. Marczewska

“…It was suggested that the dominant role in acceleration of the electrode process is played by the composition of the activated complex, which is presumably composed of solvent molecules and thiourea molecules adsorbed on to the electrode. …”
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A strategy to improve the adsorption capacity of OPs-dye pollutants from the aqueous environment using adsorbents based on 2D transition metal carbides (V2CTx) by Ali Bina, Heidar Raissi

“…Abstract Remediation of water pollution or removal of pollutant molecules by efficient substrates with long life is very important and challenging. …”
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CK2α-mediated phosphorylation of DUB3 promotes YAP1 stability and oncogenic functions by Lei Huang, Yalei Wen, Qin Guo, Caishi Zhang, Xiao Yang, Mei Li, YiXia Liu, Xinying Li, Jiaxin Tang, Xiaofeng Zhou, Qi Qi, Haoxing Zhang, Tongzheng Liu

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Crossing the Vascular Wall: Common and Unique Mechanisms Exploited by Different Leukocyte Subsets during Extravasation by Michael Schnoor, Pilar Alcaide, Mathieu-Benoit Voisin, Jaap D. van Buul

“…The endothelial adhesion molecules ICAM-1 and VCAM-1 are known as the central mediators of leukocyte adhesion to and transmigration across the endothelium. …”
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Radical Reactions in the Gas Phase: Recent Development and Application in Biomolecules by Yang Gao, Jiexun Bu, Zhou Peng, Biwei Yang

“…The majority of the molecules discussed in this review see limited fragmentation from conventional CID, and the gas phase radical reactions open up completely new dissociation channels for these molecules and therefore yield high fidelity confirmation of the structures of the target molecules. …”
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Nucleic-Acid-Binding Chromophores as Efficient Indicators of Aptamer-Target Interactions by Kwabena Sarpong, Bhaskar Datta

“…In particular, chromophore-functionalized aptamers offer a relatively simple format for detection and quantification of target molecules. We describe the use of nucleic-acid-staining reagents as an effective tool for detecting and signaling aptamer-target interactions. …”
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Structure and Stability of B10N14: Cages, Sheets, and Rings by Melanie Walker, Kelvin Jones, DaiQuan Noble, Marquavias Walker, Douglas L. Strout

“…In the current study, theoretical calculations are carried out on molecules of B10N14 to determine energetically favorable isomers. …”
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Quest and designing of organic molecular frameworks for efficient hole transport materials by Priya Singh, Aditya Kumar, Ajeet Singh

“…We have also performed time-dependant density functional theory (TD-DFT) calculations to investigate the optical, electronic and charge transport properties of designed molecules. Calculated results infer that the designed molecules display characteristic traits of a HTM. …”
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