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441
Combining and congruence evaluation of phylogenetic signals from different genes based on geometric approach
Published 2017-02-01“…A new Euclidean distance based algorithm is used for analysis of congruence and combining molecular genetic data. This approach is called geometric, since Euclidean distance satisfies all metric axioms and the points representing the sequences can be placed in a geometric space without distorting the mutual distances and can be endowed with the coordinates in this space. …”
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442
Role of apoptosis genes in aggression revealed using combined analysis of ANDSystem gene networks, expression and genomic data in grey rats with aggressive behavior
Published 2018-01-01“…It was shown that polymorphic and differentially expressed genes were statistically significantly overrepresented among ge nes interacting with neuronal apoptosis genes (p value < 0.01). Three moleculargenetic chains describing connections between polymorphic and neuronal apoptosis genes mediated by differentially expressed genes were reconstructed. …”
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443
Analysis of a Family with Brugada Syndrome and Sudden Cardiac Death Caused by a Novel Mutation of SCN5A
Published 2022-01-01“…The newly discovered mutation site c.4313dup(p.Trp1439ValfsTer32) in exon 25 of SCN5A may be the molecular genetic basis of the family with Brugada syndrome.…”
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444
Perspectives of using Illumina MiSeq for identification of arbuscular mycorrhizal fungi
Published 2020-04-01“…In our work, we have successfully used universal primers ITS3 and ITS4 for the sequencing in Illumina MiSeq of the 5.8S rDNA – ITS2 region of the 35S rRNA genes, which contain both a conservative and variable regions. The molecular genetic approach for AMF identification was quite effective and allowed us to reliably identify eight of nine isolates to the species level: five isolates of Rhizophagus irregularis, and one isolate of R. invermaius, Paraglomus laccatum, and Claroideoglomus etunicatum, respectively. …”
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445
Genetic diversity assessment in pea cultivars and lines using the SSR analysis
Published 2020-10-01“…However, the distribution of a number of microsatellite alleles in the genotypes of specific lines and cultivars of this valuable pulse crop remains practically unexplored.Materials and methods. Molecular genetic polymorphism was studied in 40 pea cultivar accessions of different ecological and geographical origin from the Vavilov Institute’s genebank of plant genetic resources or developed at regional breeding centers. …”
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446
Computer analysis of regulation of hepatocarcinoma marker genes hypermethylated by HCV proteins
Published 2023-01-01“…Epigenetic changes are known to play an important role in the molecular genetic mechanisms of virus-induced oncogenesis. …”
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447
Clinical manifestations in Egyptian Pompe disease patients: Molecular variability and enzyme replacement therapy (ERT) outcomes
Published 2025-01-01“…The diagnosis was confirmed by molecular genetic testing using PCR amplification and sequencing of the acid alpha-glucosidase (GAA) gene. …”
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448
Using achievements of fruit crop genetics and breeding: a contribution from the Michurinsk Department of the Vavilov Society of Geneticists and Breeders
Published 2016-09-01“…On the basis of molecular-genetic analysis of apple initial forms and hybrid seedlings, there were identified targeted alleles of monogenic scab resistance genes including dominant homozygous genotype (Rvi6Rvi6) and also alleles of genes involved in the control of the biosynthesis of ethylene (Md-ACS1 and Md-ACO1) and expansin (Md-Exp7) controlling fruit long shelf life and pulp firmness.…”
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449
Problems of mini-pig breeding
Published 2021-06-01“…In addition, in the breeding of foreign mini-pigs, molecular genetic methods are used to monitor heterozygosity. …”
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450
Molecular basis and genetics of hypohidrotic ectodermal dysplasias
Published 2023-11-01“…The domain structures of the corresponding proteins are considered, as well as the molecular genetic pathways in which they are involved. …”
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451
NGS sequencing in barley breeding and genetic studies
Published 2020-07-01“…Molecular markers have also been used extensively for molecular genetic mapping and QTL analysis. In 2012, the barley genome sequencing was completed, which provided a broad range of new opportunities – from a more efficient search for candidate genes controlling economically important traits to genomic selection. …”
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452
ON THE EQUIVALENCE OF DELAYED ARGUMENTS AND TRANSFER EQUATIONS FOR MODELING DYNAMIC SYSTEMS
Published 2018-03-01“…This property is extremely important for the modeling of molecular genetic systems in which processes of DNA, RNA, and protein synthesis proceed at variable rates and need to be considered in certain problems, what can easily be done in models constructed using the mathematical tool of partial derivatives.…”
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453
Direct and Indirect Methods for Studying Human Gut Microbiota
Published 2022-08-01“…Aim: To review the main methods of intestinal microbiota studying.Key points. Currently, molecular genetic methods are used mainly for basic research and do not have a unified protocol for data analysis, which makes it difficult to implement them in clinical practice. …”
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454
Reconstruction and computational analysis of the microRNA regulation gene network in wheat drought response mechanisms
Published 2025-01-01“…Wheat adaptation to water deficit is ensured by complex molecular genetic mechanisms, including the coordinated work of multiple genes regulated by transcription factors and signaling non-coding RNAs, particularly microRNAs (miRNAs). miRNA-mediated regulation of gene expression is considered one of the main mechanisms of plant resistance to abiotic stresses. …”
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455
MOLECULAR TYPING OF METHICILLIN-SUSCEPTIBLE STAPHYLOCOCCUS AUREUS (MSSA), ISOLATED FROM MONKEYS, BASED ON COAGULASE GENE POLYMORPHISM
Published 2019-10-01“…The present study is devoted to the study of the polymorphism of a variable region of the coagulase gene and to the typing of Staphylococcus aureus isolates from monkeys of different species kept at Adler monkey farm. 115 Staphylococcus aureus isolates were studied using phenotypic and molecular genetic methods. Genotyping was performed using PCR, real-time PCR and PCR with subsequent restriction fragment length polymorphism analysis (PCR-RFLP). …”
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456
Association of autistic personality traits with the EEG scores in non-clinical subjects during the facial video viewing
Published 2025-01-01“…The software module we are developing can be integrated with modules that allow identifying molecular genetic markers of personality traits, including traits that determine the predisposition to mental pathologies.…”
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457
Efficiency of using SNP markers in the <i>MSTN</i> gene in the selection of the Pushkin breed chickens
Published 2020-01-01“…Traditional selection based on phenotypic evaluation is characterized by low efficiency with a low character inheritance ratio and is difficult to apply in small groups of animals and birds bred in bioresource collections. The use of molecular genetic markers associated with economically important traits makes it possible to carry out early selection of birds. …”
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458
Genetics and pathophysiology of low-renin arterial hypertension
Published 2019-01-01“…Genetic studies of some recent decades using both family analysis and modern molecular genetic technologies have revealed the main mechanisms underlying low-renin hypertension, which can be classifed as certain syndromes with well-defned genetic and clinical features. …”
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459
Genotypic variability of Pinus sylvestris L. on the drought-resistance attribute
Published 2019-02-01“…The results of vegetative and generative sphere analysis of individual Scotch pine trees with the help of biotechnology, molecular-genetic and cytogenetic method are given in this study. …”
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460
Polymorphism of RAPD and ISSR markers in grain amaranth species
Published 2017-04-01“…Different molecular genetic markers are effectively used in agricultural genetic selection programs. …”
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