Prenatal Three-Dimensional Ultrasound Detection of Adducted Thumbs in X-Linked Hydrocephaly: Two Case Reports with Molecular Genetic Studies by Edgardo Corral, Andres Barrios, Monica Isnard, Pascale Saugier-Veber, Sophie M. Fortier, Sarah Durrin, Waldo Sepulveda

“…We describe two cases of X-linked hydrocephaly with associated adducted thumbs that were diagnosed prenatally with the combined use of three-dimensional (3D) ultrasound and fetal blood sampling for cytogenetic and molecular analyses. This report suggests that 3D ultrasound can facilitate the identification of adducted thumbs in fetuses affected by X-linked hydrocephaly and supports evaluation of the fetal hands as an integral part of the ultrasound anatomical assessment in male fetuses with hydrocephaly secondary to aqueductal stenosis.…”
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Computational evaluation on spectroscopic (FT-IR, Raman), electronic and biological, and NLO properties of cirsilineol by DFT, ADMET, and molecular docking method by Tirth Raj Paneru, Poonam Tandon, Bhawani Datt Joshi

“…Spectral measurement for IR and Raman provided evidence of intra-molecular hydrogen bonding of the OH group in ring R1. …”
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Recent advances in immunohistochemical and molecular profiling for differential diagnosis between giant cell-rich lesions and tenosynovial giant cell tumors by Jiro Ichikawa, Tomonori Kawasaki, Satoshi Ochiai, Masanori Wako, Tetsuo Hagino, Kaoru Aoki, Kojiro Onohara

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Investigation of survival and prognostic factors in triple negative molecular subtype male breast cancer patients: A population-based study by Ahmet Necati Sanli, Bilal Turan

“…It is encouraging that triple negative molecular subtype breast cancer, which is an aggressive tumor, is less common in men. …”
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Corrigendum to “Antitumor Molecular Mechanism of Chlorogenic Acid on Inducting Genes GSK-3β and APC and Inhibiting Gene β-Catenin” by Ruoshi Xu, Qiumei Kang, Jie Ren, Zukun Li, Xiaoping Xu

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GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease by Wang Y, Fang J, Yuan Q, Yu J, Hu J

“…Finally, the expression of hub genes was further validated in a mouse model of TBI induced by controlled cortical impact (CCI).Results: Shared transcriptional signatures between TBI and PD were uncovered, highlighting overlapping molecular networks and pathways. The glutathione peroxidase 3 (GPX3) gene emerged as a pivotal hub gene, with its expression significantly altered in both TBI and PD datasets.Conclusion: This study underscores the critical role of GPX3 in the molecular intersection of TBI and PD, suggesting it as a novel and potential therapeutic target, offering new insights into potential therapeutic strategies.Keywords: traumatic brain injury, Parkinson’s disease, bioinformatics, oxidative stress, mitochondrial dysfunction, neurodegenerative diseases…”
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Molecular cloning and expression dynamics of Atrogin-1 in muscle tissue of Russian sturgeon (Acipenser gueldenstaedtii) under high salt stress by Yong-Juan Mo, Yi-Li Gao, Shi-Jjian Xu, Bin Wang, Jingping Wu, Peng Yu, Ming Li, Xiangtao Kang, Zhi-Qiang Han

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Multiple machine learning-based integrations of multi-omics data to identify molecular subtypes and construct a prognostic model for HNSCC by Xiaoqin Luo, Chao Li, Gang Qin

“…Developing personalized treatment strategies based on the molecular heterogeneity of HNSCC is essential to enhance therapeutic efficacy and prognosis. …”
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Effect of High, Medium, and Low Molecular Weight Hyaluronan on Inflammation and Oxidative Stress in an In Vitro Model of Human Nasal Epithelial Cells by Giusy Daniela Albano, Anna Bonanno, Luca Cavalieri, Eleonora Ingrassia, Caterina Di Sano, Liboria Siena, Loredana Riccobono, Rosalia Gagliardo, Mirella Profita

“…Hyaluronan (HA) in its high molecular weight form (HMW-HA) shows anti-inflammatory responses in contrast to low and medium molecular weight HA (LMW-HA and MMW-HA). …”
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Orientin Reduces the Effects of Repeated Procedural Neonatal Pain in Adulthood: Network Pharmacology Analysis, Molecular Docking Analysis, and Experimental Validation by Dong-Dong Guo, Hai-Yan Huang, Hai-E. Liu, Kun Liu, Xing-Jing Luo

“…The aim of this study was to systematically explore the effect of orientin on repeated procedural neonatal pain using network pharmacology, molecular docking analysis, and experimental validation. …”
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Reconstruction of Alzheimer’s Disease Cell Model In Vitro via Extracted Peripheral Blood Molecular Cells from a Sporadic Patient by Sijun Liu, Yuying Zhao, Xiaoying Su, Chengcheng Zhou, Peifen Yang, Qiusan Lin, Shijun Li, Hanxu Tan, Qi Wang, Changjun Wang, Qingguang Wu

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Molecular Targets of Shenqi Dihuang, A Traditional Chinese Herbal Medicine, and Its Potential Role in Renal Cell Carcinoma Therapy by Xinglin Chen, Tongtong Zhang, Xiangyang Zhan, Xinyue Zang, Xinyu Zhai, Zhong Wan, Minyao Ge, Mingyue Tan, Jianyi Gu, Dongliang Xu

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Molecular Characterization and Clinical Characteristics of m5C-Based RNA Methylation in Spinal Cord Injury: Validated by qPCR by Liang Cao, Wen Jun Pi, Qiang Zhang, Qing Li

“…Analysis of the correlation between the gene sets of m5C-based regulators of RNA modification and immune-cell infiltration and immune response revealed Dnmt1, DNA methyltransferases 3A (Dnmt3a), Mbd2, and Ung to be positive regulators of the immune microenvironment, and Zbtb4 may negatively regulate the immune environment. Then, two molecular subtypes were identified based on 16 m5C-regulated genes. …”
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Differentiation and Molecular Properties of Mesenchymal Stem Cells Derived from Murine Induced Pluripotent Stem Cells Derived on Gelatin or Collagen by Chizuka Obara, Kazuya Takizawa, Kenichi Tomiyama, Masaharu Hazawa, Ai Saotome-Nakamura, Takaya Gotoh, Takeshi Yasuda, Katsushi Tajima

“…The present study compared molecular properties and differentiation potential of derived mouse iPS-MSCs by deriving on gelatin or collagen-coated surfaces. …”
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Antifungal, Insecticidal, and Repellent Activities of Rosmarinus officinalis Essential Oil and Molecular Docking of Its Constituents against Acetylcholinesterase and β-Tubulin by Ghizlane Houzi, Youness El abdali, Ghada Beniaich, Mohamed Chebaibi, Mohamed Taibi, Amine Elbouzidi, Samiha Kaioua, Abdeslam Asehraou, Mohamed Addi, Khalid Chaabane, Rachid Flouchi, Aimad Allali, Soad Khal-Layoun

“…Repellent capacity and toxicity were evaluated through inhalation and contact tests on Callosobruchus maculatus. Molecular docking techniques were utilized to test the insecticidal and antifungal activities of rosemary EO. …”
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GENETIC COMPLEXITY AND CONTEXT SPECIFICITY OF TRAITS IMPROVING WHEAT YIELD UNDER DROUGHT CONDITIONS by V. A. Krupnov

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pH‐Dependent Assembly and Stability of Toll‐Like Receptor 3/dsRNA Signaling Complex: Insights from Constant pH Molecular Dynamics and Metadynamics Simulations by Penghui Li, Mingsong Shi, Yibo Wang, Qiong Liu, Xiubo Du, Xiaohui Wang

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Molecular Phylogeny and Morphology Reveal Four New Species of <i>Conocybe</i> (Bolbitiaceae, Agaricales) from the Qinghai-Xizang Plateau, China by Xi-Xi Han, Dorji Phurbu, Bin Cao, Jia-Xin Li, Xin-Yu Zhu, Lin-Hui Liu, Naritsada Thongklang, Kevin D. Hyde, Rui-Lin Zhao

“…Molecular analyses, utilizing multi-gene sequence data (ITS, nrLSU, and <i>tef-1α</i>), support the taxonomic position of these new species within this genus as new species. …”
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MORPHOLOGY, MOLECULAR IDENTIFICATION, PATHOGENICITY AND FIRST REPORT OF FUSARIUM EQUISETI ASSOCIATED WITH ROOT ROT AND WILT DISEASE OF CATHARANTHUS ROSEUS IN BAGHDAD, IRAQ by Lara B. Yasir, Bushra Subair Abdulsada Almaliky

“…Also, these fungi were diagnosed based on the microscopic and molecular characteristics. The results of the molecular identification showed that the three isolates FeL1, FeL2 and FeL9 belong to the F. equiseti and they showed a conformity ratio of 99.60, 99.39 and 95.97 respectively when compared with the nucleotide sequences of isolates of F. equiseti gene bank of Brazil JQ936262, Ghana OL998428 and China GU586830 respectively. …”
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Genotyping and Molecular Characterization of VP6 and NSP4 Genes of Unusual Rotavirus Group A Isolated from Children with Acute Gastroenteritis by Charilaos Dellis, Elizabeth-Barbara Tatsi, Dimitra-Maria Koukou, Filippos Filippatos, Evangelia-Eirini Vetouli, Emmanouil Zoumakis, Athanasios Michos, Vasiliki Syriopoulou

“…The aim of this study was to genotype the VP6 and NSP4 genes and molecularly characterize the NSP4 and VP6 genes of unusual RVA. …”
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