Frequency and Prognostic Impact of CDKN2A/B Alteration in Oligodendrogliomas: Systematic Review and Meta-analysis by Satoshi NAKASU, Shoichi DEGUCHI, Yoko NAKASU

“…This study systematically reviewed and meta-analyzed the literature on molecularly defined oligodendrogliomas (mOlig) to find the frequency and prognostic significance of CDKN2A/B gene alterations. …”
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Algunas especificidades en torno al cáncer de pulmón by Ana María Nazario Dolz, Dunia Álvarez Matos, Luis Castillo Toledo, María Victoria Miyares Peña, Anabell Garbey Nazario

“…Conclusiones: El cáncer de pulmón de células no pequeñas es el más frecuente y mortal  a escala mundial, en una población ya envejecida, donde los factores moleculares, genéticos y ambientales juegan un papel en su desarrollo y continúan siendo objeto de estudios, de ahí que la estadificación TNM sea  de vital importancia al determinar las decisiones del tratamiento y del pronóstico. …”
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Highly proliferating cancer cells function as novel prognostic biomarkers for lung adenocarcinoma with particular usefulness for stage IA risk stratification by Yanlu Xiong, Yongfu Ma, Jie Lei, Jianfei Zhu, Nianlin Xie, Feng Tian, Qiang Lu, Miaomiao Wen, Qian Zheng, Yong Han, Tao Jiang, Yang Liu

“…Abstract Background The refinement of risk stratification in lung adenocarcinoma (LUAD) plays a pivotal role in advancing precision medicine; however, the current staging classification falls short of comprehensiveness, particularly in the case of stage IA patients. We aimed to molecularly stratify LUAD patients especially for stage IA. …”
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Algunas consideraciones en torno al cáncer de esófago by José Antonio Suárez Rodríguez, Ana María Nazario Dolz, Lázaro Ibrahim Romero García, Gilberto Carlos Falcón Vilariño, Grethel Odalys Rivero Reyes

“…Conclusiones: En la etiología del cáncer de esófago, los factores moleculares, genéticos y ambientales juegan un papel importante. …”
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Von Hippel-Lindau (VHL) inactivation in sporadic clear cell renal cancer: associations with germline VHL polymorphisms and etiologic risk factors. by Lee E Moore, Michael L Nickerson, Paul Brennan, Jorge R Toro, Erich Jaeger, Jessica Rinsky, Summer S Han, David Zaridze, Vsevolod Matveev, Vladimir Janout, Hellena Kollarova, Vladimir Bencko, Marie Navratilova, Neonilia Szeszenia-Dabrowska, Dana Mates, Laura S Schmidt, Petra Lenz, Sara Karami, W Marston Linehan, Maria Merino, Stephen Chanock, Paolo Boffetta, Wong-Ho Chow, Frederic M Waldman, Nathaniel Rothman

“…Renal tumor heterogeneity studies have utilized the von Hippel-Lindau VHL gene to classify disease into molecularly defined subtypes to examine associations with etiologic risk factors and prognosis. …”
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Diagnóstico y tratamiento de toxoplasmosis congénita by María Teresa Díaz Armas, Izaida Lis Montero López, Jorge Luis Sagué Larrea

“…El diagnóstico se basa en pruebas serológicas, cultivos en modelos animales o líneas celulares o métodos moleculares como la reacción en cadena de la polimerasa (PCR). …”
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Tratamiento del cáncer de pulmon portador de la mutación del receptor del factor de crecimiento epidérmico by Yoanna Ivette Flores Vega, Diana Laura Páramo González, Alejandro Perez Fonteboa, Daniel Ricardo Martínez Ávila

“…En el carcinoma de pulmón de células no pequeñas se han identificado la presencia de una serie de alteraciones moleculares entre ellas, la mutación del receptor del factor de crecimiento epidérmico. …”
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Gliomas Difusos do Adulto: Prevalência da Mutação IDH1 em um Hospital Universitário by Vitor Bonk Rizzo, Michelle Arrata Ramos, Eduardo Morais de Castro, Pedro Helo dos Santos Neto, Samya Hamad Mehanna

“…São classificados pelo padrão de infiltração, grau histopatológico e alterações moleculares. Mutações na enzima isocitrato desidrogenase (IDH), identificada em alguns tumores gliais, marcam o início da carcinogênese, aumentando a funcionalidade das enzimas metabólicas IDH1 e IDH2. …”
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Inflamación crónica y enfermedades degenerativas by Alvaro Paul Moina-Veloz, Patricio Gabriel Cargua-Inca, Darwin Bladimir Tinillo-Tapia, Bryan Alexander Cueva-Jara

“…Desarrollo: las respuestas inflamatorias se activan por patrones moleculares que se asocian al daño, estas liberan las sustancias nocivas física s coma químicas o aquellos estímulos metabólicos que son agentes estériles durante el estrés celular, posterior a la infección se producen lipoxinas, reoslvinas, maresina y proteínas afines a la inflamación. …”
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Improving natural red pigment production by Streptomyces phaeolivaceus strain GH27 for functionalization of textiles with in silico ADME prediction by Gehad H. El Sayed, Mohamed Fadel, Rasha Fouad, Hend M. Ahmed, Ahmed A. Hamed

“…Abstract The red pigment was recovered from the S. phaeolivaceus GH27 isolate, which was molecularly identified using 16S rRNA gene sequencing and submitted to GenBank as OQ145635.1. …”
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Whole-Genome Sequencing and Comparative Genome Analysis Provided Insight into the Predatory Features and Genetic Diversity of Two Bdellovibrio Species Isolated from Soil by Omotayo Opemipo Oyedara, Aldo Segura-Cabrera, Xianwu Guo, Temidayo Oluyomi Elufisan, Rafael Alejandro Cantú González, Mario A. Rodríguez Pérez

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Advancing Food Security with Farmed Edible Insects: Economic, Social, and Environmental Aspects by José E. Aguilar-Toalá, Abraham M. Vidal-Limón, Andrea M. Liceaga

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Enhancing the performance of polyfarnesene-based bio-rubbers with surface-modified cellulose nanocrystals and nanofibers by Luis Valencia, Ilse Magaña, Marisol Gálvez, Francisco Javier Enríquez-Medrano, Teresa Córdova, Cristal Cabrera, José Luis Olivares Romero, Héctor Ricardo López-González, Ramón Díaz de León

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Identification of Potential Vectors and Detection of Rift Valley Fever Virus in Mosquitoes Collected Before and During the 2022 Outbreak in Rwanda by Isidore Nsengimana, Emmanuel Hakizimana, Jackie Mupfasoni, Jean Nepomuscene Hakizimana, Augustino A. Chengula, Christopher J. Kasanga, Gillian Eastwood

“…Of 238 pools collected during the outbreak, RVFV was detected molecularly from five pools (two pools of <i>Cx. quinquefasciatus</i>, two pools of <i>Anopheles ziemanni</i>, and one pool of <i>Anopheles gambiae</i> sensu lato), and RVFV was isolated from the two pools of <i>Cx. quinquefasciatus</i>, from Kayonza and Rwamagana districts, respectively. …”
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Propiedades fisicoquímicas de la leche de cabra en unidades productivas a pequeña escala by Luis Chel-Guerrero, Carolina Barrientos-Ávila, Arturo Castellanos-Ruelas, Santiago Gallegos-Tintoré, David Betancur-Ancona

“…El patrón electroforético de las caseínas mostró bandas más abundantes con pesos moleculares de 20 a 36 kDa. Conclusiones. La composición de la leche de cabra producida resultó ser superior, con ventajas nutricionales, y potenciales beneficios a la salud respecto a la leche de otras especies. …”
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Biopriming of Maize with their endophyte Aspergillus fumigatus reinforces their resistance to salinity stress and improves their physiological traits by Marwa A. Yassin, Nelly George, Lamis Shabaan, Yousra Gouda

“…The pattern of the endophytic fugal isolates was plausibly changed with the salt concentration for both plant types, Aspergillus fumigatus isolate was emerged with the higher NaCl concentration (400–500 mM), and their morphological identity was molecularly confirmed and deposited into Genbank with accession # PQ200673. …”
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Phase 3 Study of Talazoparib Plus Enzalutamide Versus Placebo Plus Enzalutamide as First‐Line Treatment in Patients With Metastatic Castration‐Resistant Prostate Cancer: TALAPRO‐2... by Nobuaki Matsubara, Hideaki Miyake, Hiroji Uemura, Atsushi Mizokami, Hiroaki Kikukawa, Takeo Kosaka, Kazuo Nishimura, Motonobu Nakamura, Kazuki Kobayashi, Atsushi Komaru, Yuko Mori, Shigeyuki Toyoizumi, Natsuki Hori, Yoshiko Umeyama, Hirotsugu Uemura

“…ABSTRACT Background In TALAPRO‐2, the poly(ADP‐ribose) polymerase inhibitor talazoparib plus the androgen receptor–signaling inhibitor enzalutamide improved radiographic progression‐free survival (rPFS) versus placebo plus enzalutamide (hazard ratio [HR] = 0.63; 95% CI, 0.51–0.78) in molecularly unselected patients with metastatic castration‐resistant prostate cancer (mCRPC). …”
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Degradação de ibuprofeno por eletrólise sob plasma elétrico de alta tensão e baixa corrente, com sistema multieletrodos by Rodrigo Marlière de Freitas, Efraim Lázaro Reis, César Reis, José Flávio Moreira, Alexsandro Antônio Matias, Odilaine Inácio de Carvalho Damasceno

“…Este é um processo eletrolítico não faradáico, onde o plasma é sustentado por descargas entre o ânodo e o eletrólito líquido no seu entorno, causando efeitos físicos e químicos variados, produzindo espécies químicas radicalares e moleculares, todos de alta reatividade. Na célula eletroquímica utilizada os ânodos de fios de platina ficam expostos cerca de 1,5 mm na solução enquanto o cátodo de grafite espectroscópico fica envolto por um tubo de plástico com furos laterais. …”
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Pathological variants in HPV-independent vulvar tumours by Sanja A. Farkas, Alvida Qvick, Gisela Helenius, Gabriella Lillsunde-Larsson

“…The main outcome of this study show that vulvar cancer harbour genetic variations of different types and specifically, HPV-independent tumours are molecularly very heterogeneous and harboured more SNVs while HPV-associated tumors more frequently presented with gene amplifications. …”
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Guía colombiana de tuberculosis genitourinaria by Jhonatan S. Santafé-Galvis, Paula A. Peña-Murcia, Liz K. Solano-Perdomo, Diego A. Riatiga-Ibáñez, Sofía E. Muñoz-Medina

“…Puede diagnosticarse por medio de pruebas bacteriol&oacute;gicas, serol&oacute;gicas, moleculares o histopatol&oacute;gicas. En cada caso se requiere una evaluaci&oacute;n imagenol&oacute;gica adecuada para determinar el compromiso org&aacute;nico o las secuelas, as&iacute; como la estrategia para el manejo quir&uacute;rgico. …”
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