Preventive but Not Curative Efficacy of Celecoxib on Bladder Carcinogenesis in a Rat Model by José Sereno, Belmiro Parada, Flávio Reis, Fernanda X. Cunha, Edite Teixeira-Lemos, Patrícia Garrido, Rui Pinto, Petronila Rocha-Pereira, Paula Neto, José Ruivo, Paulo Rodrigues-Santos, Sara Nunes, Alfredo Mota, Arnaldo Figueiredo, Frederico Teixeira

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Investigation of Novel Aronia Bioactive Fraction-Alginic Acid Nanocomplex on the Enhanced Modulation of Neuroinflammation and Inhibition of Aβ Aggregation by Bong-Keun Jang, Soo Jung Shin, Hyun Ha Park, Vijay Kumar, Yong Ho Park, Jeom-Yong Kim, Hye-Yeon Kang, Sunyoung Park, Youngsun Kwon, Sang-Eun Shin, Minho Moon, Beom-Jin Lee

“…To solve the instability of anthocyanins, we combined aronia bioactive factions (ABFs) and alginic acid via electrostatic molecular interactions and created an ABF–alginic acid nanocomplex (AANCP). …”
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The Long-Term Immunity of a Microneedle Array Patch of a SARS-CoV-2 S1 Protein Subunit Vaccine Irradiated by Gamma Rays in Mice by Eun Kim, Muhammad S. Khan, Juyeop Shin, Shaohua Huang, Alessandro Ferrari, Donghoon Han, Eunjin An, Thomas W. Kenniston, Irene Cassaniti, Fausto Baldanti, Dohyeon Jeong, Andrea Gambotto

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Effects of pesticide dichlorvos on liver injury in rats and related toxicity mechanisms by Pengcheng Zhang, Zixian Zhou, Jiaqi Yao, Yuhong Jiang, Hang Lei, Zhijun Xie, Juan Li, Xianlin Zhao, Lv Zhu, Meihua Wan, Ling Liu, Wenfu Tang

“…Our study offers new insights into the molecular mechanisms of liver injury following organophosphate poisoning and suggests that IRGM may represent a novel therapeutic target for DDVP-induced liver injury.…”
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Development of an Efficient and Generalized MTSCAM Model to Predict Liquid Chromatography Retention Times of Organic Compounds by Mengdie Fan, Chenhui Sang, Hua Li, Yue Wei, Bin Zhang, Yang Xing, Jing Zhang, Jie Yin, Wei An, Bing Shao

“…Then, data augmentation was performed within each category using simplified molecular input line entry system (SMILES) enumeration combined with structural similarity expansion. …”
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Metal complexes in cells: from design of catalytic antioxidants to imaging metal ions and designing metal-based probes in X-ray fluorescence and IR-imaging, a multidisciplinary col... by Policar, Clotilde, Delsuc, Nicolas, Bertrand, Hélène Charlotte

“…Starting from the description of the main features of an antioxidant cell-protecting metalloenzyme, the superoxide dismutase (SOD), we will delineate the main parameters to be controlled to design low-molecular weight (LMW) metal complexes meant to mimic its activity: choice of the metal cation, tuning of the redox potential, and modulation of the charge. …”
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Development of antibacterial magnetic clay-based nanocomposites for water treatment by Horue, Manuel, Barraqué, Facundo, Montes, María Luciana, Zelaya-Soulé, María Emilia, Morantes, César Fernández, Urruchua, Florencia Camila, Correa, Hilda Edith, Castro, Guillermo Raul, Fernandez, Mariela Alejandra

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The bacterial microbiome of symbiotic and menthol-bleached polyps of long-term aquarium-reared Galaxea fascicularis by Puntin, Giulia, Wong, Jane C. Y., Röthig, Till, Baker, David M., Sweet, Michael, Ziegler, Maren

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Nationwide cervical precancer screening in Ghana: concurrent HPV DNA testing and visual inspection under an expanded hub-and-spoke model by Kofi Effah, John Allotey, Ethel Tekpor, Comfort Mawusi Wormenor, Joseph Emmanuel Amuah, Ernest Antwi-Boasiako, Erasmus Nikoi Kotey, Seyram Kemawor, Isaac Gedzah, Helena Maame Ama Frempong, Stephen Danyo, Edna Sesenu, Bernard Hayford Atuguba, Nana Owusu Mensah Essel, Patrick Kafui Akakpo

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Dynamics of blood microsatellite instability (bMSI) burden predicts outcome of a patient treated with immune checkpoint inhibitors: a case report of hyperprogressive disease by Daria Kravchuk, Alexandra Lebedeva, Alexandra Lebedeva, Olesya Kuznetsova, Olesya Kuznetsova, Alexandra Kavun, Anastasiia Taraskina, Ekaterina Belova, Ekaterina Belova, Ekaterina Belova, Tatiana Grigoreva, Tatiana Grigoreva, Egor Veselovsky, Vladislav Mileyko, Vladislav Mileyko, Vladislav Nikulin, Lidia Nekrasova, Alexey Tryakin, Mikhail Fedyanin, Mikhail Fedyanin, Mikhail Fedyanin, Maxim Ivanov, Maxim Ivanov

“…Microsatellite instability (MSI) is a widely studied molecular signature, which is associated with long-term benefit in patients treated with immune checkpoint inhibitor therapy. …”
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Structure of mycoses of the skin and its appendices in HIV-infected patients by V.D. Moskaliuk, I.I. Kravchuk, Yu.O. Randiuk, I.V. Balaniuk

“…The diagnosis of HIV infection was established according to the International Classification of Diseases of the 10th revision (ICD-10) and verified by the detection of specific serological and molecular biological markers of HIV. Mycological examination included micro­scopy of pathological material and cultural diagnosis. …”
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Improved Efficacy of a Predictive Model for Swallowing-Induced Breakthrough Pain Based on a Redefined Delineation Method in Locally Advanced Nasopharyngeal Carcinoma by Jian-Da Sun, MD, Ze-Kai Chen, MM, Shu-Peng Liu, PhD, Feng Ye, MD, Ting-Xi Tang, MD, Zhen-Hua Zhou, MD, Han-Bin Zhang, MM, Long-Shan Zhang, MD, Ting Xiao, BS, Lin-Lin Xiao, MM, Xiao-Qing Wang, MD, Jian Guan, MD

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DNMT3A Mutations in Patients with Acute Myeloid Leukemia in South Brazil by Annelise Pezzi, Lauro Moraes, Vanessa Valim, Bruna Amorin, Gabriela Melchiades, Fernanda Oliveira, Maria Aparecida da Silva, Ursula Matte, Maria S. Pombo-de-Oliveira, Rosane Bittencourt, Liane Daudt, Lúcia Silla

“…Acute myeloid leukemia (AML) is a complex and heterogeneous hematopoietic tissue neoplasm. Several molecular markers have been described that help to classify AML patients into risk groups. …”
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Spatiotemporal dynamics of early oogenesis in pigs by Wei Ge, Yi-Lin Niu, Yu-Kang Li, Li Li, Han Wang, Wen-Wen Li, Tian Qiao, Yan-Ni Feng, Yu-Qing Feng, Jing Liu, Jun-Jie Wang, Xiao-Feng Sun, Shun-Feng Cheng, Lan Li, Wei Shen

“…RNA velocity analysis with ST identifies the molecular characteristics and spatial dynamics of granulosa cell lineages originating from the cortical and medullary regions in pig ovaries. …”
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Metformin Increases Protein Phosphatase 2A Activity in Primary Human Skeletal Muscle Cells Derived from Lean Healthy Participants by Aktham Mestareehi, Xiangmin Zhang, Berhane Seyoum, Zaher Msallaty, Abdullah Mallisho, Kyle Jon Burghardt, Anjaneyulu Kowluru, Zhengping Yi

“…The primary effects of metformin include decreasing glucose production in the liver and decreasing insulin resistance in the skeletal muscle. However, the molecular mechanism of metformin’s action in skeletal muscle is not well understood. …”
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Hypoxia-tropic delivery of nanozymes targeting transferrin receptor 1 for nasopharyngeal carcinoma radiotherapy sensitization by Ruofei Zhang, Yanfang Shen, Xiaoying Zhou, Jianru Li, Hanqing Zhao, Zixia Zhang, Jun Zhao, Hongjun Jin, Shuanshuan Guo, Hui Ding, Guohui Nie, Zhe Zhang, Ying Wang, Xiyun Yan, Kelong Fan

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Artificial intelligence-enabled non-invasive ubiquitous anemia screening: The HEMO-AI pilot study on pediatric population by Daniel Gordon, Jason Hoffman, Keren Gamrasni, Yotam Barlev, Alex Levine, Tamar Landau, Ronen Shpiegel, Avishai Lahad, Ariel Koren, Carina Levin, Osnat Naor, Hannah Lee, Xin Liu, Shwetak Patel, Gilad Chayen, Michael Brandwein

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Room temperature self-assembly and nonenzymatic electrochemical sensing performance of transition metal-embedded wheel-shaped tungstophosphates by Wen-Da Liu, Hao-Tian Zhu, Xue Zhang, Fang Su, Xiao-Jing Sang, Xiao-Lan Zhang, Lan-Cui Zhang

“…Under heat-free conditions, three wheel-shaped [P8W48O184]40− ({P8W48})-based polyoxometalates (POMs) were controllably synthesized via the reaction of a hexavacant Dawson-type tungstophosphate, K12[H2P2W12O48]·24H2O (K-{P2W12}), with simple transition metal (TM) (TM = Mn, Co, and Ni) salts in room temperature aqueous solutions. The molecular formulas of the POMs were Na24[Mn8(H2O)32P8W48O184]·58H2O (1), K4Na16H4[Co8(H2O)32P8W48O184]·76H2O (2), and Na20H4[Ni8(H2O)32P8W48O184]·72H2O (3). …”
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Conjugated Polyvinyl Alcohol Modified SnO2 for Efficient Visible Light Photocatalytic Reduction of Cr(VI) by Shaojie Chen, Yuanyuan Luo, Yuhan Xu, Ying Chen, Yinxing Jiang, Zhao Li, Lin Tian, Furong Wang, Yuanyuan Liu, Jing Li

“…When CPVA/SnO2 was exposed to visible light, photogenerated electrons on the lowest unoccupied molecular orbital (LUMO) of CPVA were efficiently transferred to the surface of SnO2 through the CPVA/SnO2 heterojunction, reducing electron-hole recombination while also photosensitizing the photocatalyst and promoting efficient photocatalysis under visible light illumination. …”
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Improvement of crop production in controlled environment agriculture through breeding by Krishna Bhattarai, Andrew B. Ogden, Sudeep Pandey, Germán V. Sandoya, Ainong Shi, Amol N. Nankar, Murukarthick Jayakodi, Heqiang Huo, Tao Jiang, Pasquale Tripodi, Chris Dardick

“…The availability of published genomes and trait-linked molecular markers should enable rapid progress in the breeding of CEA-specific food crops that will help drive the growth of this industry.…”
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